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Increased interferon I signaling, DNA damage response and evidence of T-cell exhaustion in a patient with combined interferonopathy (Aicardi-Goutières Syndrome, AGS) and cohesinopathy (Cornelia de Lange Syndrome, CdLS)
Published 2025-01-01“…Conclusions A rare case of a patient bearing two genetic lesions (responsible for AGS/CdLS syndromes) exhibits distinctive features of genomic damage and interferon responses. Immune phenotype revealed granulocytic skewing and absence of activated T cells compatible with chronic antigenic stimulation and/or homing of these cells at sites of inflammation.…”
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Psychometric Validation of the Hepatitis C Symptom and Impact Questionnaire (HCV-SIQv4) in a Diverse Sample of Adults with Chronic Hepatitis C Virus Infection Treated with an Interferon-free Simeprevir-containing Regimen
Published 2019-02-01“…**Methods:** PRO data were pooled from three Phase IIb and III trials evaluating interferon-free simeprevircontaining regimens for treatment of chronic HCV infection. …”
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Biochemical Evolution and Histological Response of Patients with Hepatitis C Undergoing Antiviral Therapy.
Published 2011-07-01Subjects: Get full text
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Association study of the JAK/STAT signaling pathway with susceptibility to COVID-19 in moroccan patient and in-silico analysis of rare variants
Published 2025-01-01Subjects: Get full text
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Therapeutic potential of targeting the IRF2/POSTN/Notch1 axis in nucleus pulposus cells for intervertebral disc degeneration
Published 2025-01-01Subjects: Get full text
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Inflammatory Cytokines—The Link between Coronavirus Disease and Abortion: A Case‐Control Study
Published 2024-12-01Subjects: Get full text
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IFN-γ/TNF-α Synergism Induces Pro-Inflammatory Cytokine and Chemokine Production by In Vitro Canine Keratinocytes
Published 2025-01-01Subjects: Get full text
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Mendelian Susceptibility to Mycobacterial Diseases (MSMD) in a 13-Year-Old Ethiopian Girl with Autosomal Dominant Interferon Gamma Receptor 1(IFN-γ R1) Defect: A Clinical Diagnostic and Treatment Challenge
Published 2022-01-01“…Treatments constitute antimycobacterial, interferon-gamma, surgery, and hematopoietic stem cell transplantation (HSCT), which is the only known curative treatment. …”
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Inhibition of STING-mediated type I IFN signaling by African swine fever virus DP71L
Published 2025-02-01Subjects: Get full text
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Intricating connections: the role of ferroptosis in systemic lupus erythematosus
Published 2025-02-01Subjects: Get full text
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Efficacy and safety of new protease inhibitor faldaprevir in treatment of hepatitis C
Published 2013-12-01Subjects: “…treatment modes without interferon…”
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The effect of interleukin-10 and transforming growth factor β-1 on HLA-DR expression in colonic epithelial cells
Published 1998-01-01Subjects: Get full text
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Decoding mitochondrial DNA damage and repair associated with H. pylori infection
Published 2025-01-01Subjects: Get full text
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Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report
Published 2024-12-01Subjects: Get full text
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