Exploring novel and potent glycogen synthase kinase-3β inhibitors through systematic drug designing approach by Shabir Ahmad Ganai, Suma Mohan, Shahid Ahmad Padder

“…Therefore, inhibiting GSK-3β activity through active-site fitting molecules may offer a favourable strategy for intercepting these disorders. This comprehensive study used multiple assays in tandem in order to explore the most potent GSK-3β inhibitor. …”
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Revising Transient-Pressure Solution for Vertical Well Intersected by a Partially Penetrating Fracture with Non-Darcy Flow Effect by Shuheng Cui, Jie Kong, Hongwei Yu, Cheng Chen, Junlei Wang

“…The principle purpose of this work is to formulate an accurate mathematical model to evaluate the transient pressure behavior of a well intercepted by a partially penetrating vertical fracture (PPVF) with non-Darcy flow effect. …”
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Performance Assessment of a Permeable Reactive Barrier on Reducing Groundwater Transport of Nitrate from an Onsite Wastewater Treatment System by Charles P. Humphrey Jr., Guy Iverson, Mike O’Driscoll

“…The implemented PRB directly influences the sampling results from a monitoring well, but it is not necessarily confirmed that it intercepts the entire groundwater flow or fully prevents aquifer contamination. …”
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A Technical Overview on Beta-Attenuation Method for the Monitoring of Particulate Matter in Ambient Air by Kritika Shukla, Shankar G. Aggarwal

“…Our review reveals that federal equivalent method (FEM) designated beta gauge monitors in various studies performed better (with slope < 1.5 and intercept < 2 µg m−3) during high RH ambient conditions against reference or federal reference method (FRM). …”
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Looking back to see forward: species diversity changes since 1980 on Bahamian reefs through diver photography by Kathleen Sullivan Sealey, Katherine Black

“…Historic photographs can be analyzed to form a complimentary timeline with more formal monitoring and sampling via benthic transects, point intercept and visual surveys. This timeline may be especially important to understand long-term trends and subtle changes associated with climate change. …”
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The Impact of R&D Input on Technological Innovation: Evidence from South Asian and Southeast Asian Countries by Lei Lv, Yuchen Yin, Yuanchang Wang

“…Through the fixed-effect intercepts of each country in the heteroscedasticity robust fixed-effect models, South Asian and Southeast Asian countries are divided into three levels, and each level lists a set of equations. …”
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Estimation of Soil Evaporation in Apple Orchards Based on Hydrogen and Oxygen Isotopes by Jialiang Huang, Yi Hua, Li Zhang, Chunxiu Yu, Kexin Chen, Linyun Gu, Yi Wu, Haoyan Wei, Min Li

“…The results indicated the following: All stable isotopic compositions of soil water fell within the lower right region of the Local Meteoric Water Line, and extreme precipitation reduced the intercept of the Evaporation Trend Line in apple orchards of varying ages. …”
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Dynamic Response of Graphitic Targets with Tantalum Cores Impacted by Pulsed 440-GeV Proton Beams by Pascal Simon, Philipp Drechsel, Peter Katrik, Kay-Obbe Voss, Philipp Bolz, Fiona J. Harden, Michael Guinchard, Yacine Kadi, Christina Trautmann, Marilena Tomut

“…The study comprises different graphite grades, such as polycrystalline, expanded and carbon-fiber reinforced graphite, and low-density graphitic foams, all candidates for beam-intercepting devices in high-power accelerators. The purpose of the tantalum core is to concentrate the large energy deposition in this high-density material that withstands the localized beam-induced temperature spike. …”
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The efficacy of a low-dose combination of febuxostat and benzbromarone versus each drug used alone for the treatment of gout by Caiyu Zheng, Caiyu Zheng, Qingwen Tong, Qingwen Tong, Zhijun Zhang, Chunmei Lin, Zhiyi Wang, Dongshu Kang, Yanmei Lin, Jianqing Tian

“…The null model without participant-specific benefits was a linear mixed model for ALT, AST, eGFR, TC, TG, LDL, UA, CRP, CA724, and 24-h uric acid with age, BMI, treatment period and treatment as fixed factors, and the intercept as a random factor by participant. The results indicated no significant differences on relevant indicators among the three treatment regimens.ConclusionOur study did not identify a difference in the efficacy of reducing uric acid excretion in gout patients when comparing conventional dose febuxostat and benzbromarone monotherapy versus low-dose combination therapy.…”
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Comparison between Hyperspectral Imaging and Chemical Analysis of Polyphenol Oxidase Activity on Fresh-Cut Apple Slices by Luna Shrestha, Boris Kulig, Roberto Moscetti, Riccardo Massantini, Elke Pawelzik, Oliver Hensel, Barbara Sturm

“…The Passing–Bablok regression had a slope of 0.8 and an intercept of 7.6. The slope of the Deming regression was 0.8 within the CI bands of 0.56 and 1.10. …”
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Daily walking habits can mitigate age-related decline in static balance: a longitudinal study among aircraft assemblers by Kazuhiko Watanabe, Shoko Iizuka, Tatsuya Kobayashi, Saki Tsushima, Sora Hirohashi, Tomohiro Yoshimi, Masayoshi Zaitsu

“…The coefficient (β) of one-leg standing time against aging was estimated using two-level multilevel linear regression with random intercepts. We also estimated the β of daily walking habits at least one hour per day. …”
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Moderating Effects of Park Accessibility and External Environment on Park Satisfaction in a Mountainous City by Hong Wu, Cong Gong, Rui Wang, Xiaoyue Niu, Yu Cao, Changhao Cao, Changjuan Hu

“…., the quality of neighborhood compound greenspaces, perceived home–park distance, walking difficulty, the convenience of coordinating other trips, external environmental quality, and perceived travel safety, in Chongqing, China. Based on an intercept survey of 301 residents, five factors significantly impacted park satisfaction. …”
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Outcome in patients undergoing postponed elective surgery during the COVID-19 pandemic (TRACE II): study protocol for a multicentre prospective observational study by Markus W Hollmann, Gert Jan Scheffer, Wolfgang Buhre, Sander van Kuijk, Seppe Koopman, Dianne de Korte-de Boer, Peter G Noordzij, Alice C Werger, Jennifer Breel, Carolien S E Bulte, Bas A in ‘t Veld, Carin G C L Wensing

“…Multivariable logistic mixed-effects regression analysis with a random intercept for hospital will be used to test group differences on the primary outcome.Ethics and dissemination Ethical approval was obtained from the Institutional Review Board of Maastricht University Medical Centre+ and Amsterdam UMC. …”
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Prevalence of Eating Disorders in Adults with Celiac Disease by V. Passananti, M. Siniscalchi, F. Zingone, C. Bucci, R. Tortora, P. Iovino, C. Ciacci

“…EDI-2 was different in pulse thinness, social insecurity, perfectionism, inadequacy, ascetisms, and interpersonal diffidence between CD and HC women, whilst only in interceptive awareness between CD and HC men. A higher EAT-26 score was associated with the CD group dependently with gastrointestinal symptoms. …”
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Assessment of temporal and spatial eutrophication index in a water dam reservoir by F. Esfandi, A.H. Mahvi, M. Mosaferi, F. Armanfar, M. Hejazi, S. Maleki

“…Due to the significant impact of suspended particles resulting from erosion of the surrounding lands on TSI value, there is an urgent need for mitigation measures to intercept eutrophication.…”
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No Modulatory Effects when Stimulating the Right Inferior Frontal Gyrus with Continuous 6 Hz tACS and tRNS on Response Inhibition: A Behavioral Study by Hannah Brauer, Navah Ester Kadish, Anya Pedersen, Michael Siniatchkin, Vera Moliadze

“…During that process, a “go” reaction is intercepted particularly by the right inferior frontal gyrus (rIFG) and presupplementary motor area (pre-SMA). …”
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Causal relationship between gastroesophageal reflux disease and chronic obstructive respiratory disease: A bidirectional Mendelian randomization study by Shan Lin, Dingfeng Lai, Wanmei He, Qingyuan Zhan

“…The absence of heterogeneity and pleiotropy was confirmed through the Cochran Q test, funnel plots, MR-Egger intercept test, and MR-PRESSO. Directional causality was further substantiated by Steiger testing. …”
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Determinants of Intraocular Pressure (IOP) of Glaucoma Patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia by Mitiku Wale Muluneh, Shewayiref Geremew Gebremichael

“…The estimated coefficient of fixed effect intercept was 25.1829, which indicates that the average IOP of the patients was 25.1829 mmHg at baseline time by excluding all covariates in the model (p value <0.0001), age (β=0.07, 95%CI 0.03, 0.11), urban residence (β = −1.60, 95%CI −2.84, −0.36), family history of glaucoma (β = 4.90, 95%CI 3.38–6.43), timolol and pilocarpine medication (β = −2.02, 95%CI −4.01, −0.03), cup-disk ratio >0.7 (β = 2.60, 95% CI 1.24–3.96), and follow-up time (β = −0.34, 95%CI −0.47, −0.21) were significantly associated with intraocular pressure of glaucoma patients. …”
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Particle Removal and Antibacterial of Nanofiber Doped with Metal and Ions Prepared by Electrospinning by Ying-Chi Jiang, Hope T. Cayron, Yu-Chen Cheng, Alvin R. Caparanga, Chang-Tang Chang

“…The nanofiber membranes prepared by electrospinning technology are easy to intercept submicron and nanoparticles. Furthermore, the electrospinning technology is simple to operate, makes fibers of various materials easy, and is convenient for assembly and replacement. …”
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Training Load and Current Soreness Predict Future Delayed Onset Muscle Soreness in Collegiate Female Soccer Athletes by Brett S. Pexa, Christopher J. Johnston, Jeffrey B Taylor, Kevin R. Ford

“…Separate linear mixed models were performed with the following day's DOMS as the outcome variable, training load and the current day's DOMS as predictor variables, and participants serving as random intercepts. # Results All training load variables significantly predicted change in DOMS, with number of decelerations (ρ=0.72, p \<0.001), minutes spent at greater than 80% of maximum heart rate (HRmax) (ρ=0.71 , p \<0.001), and distance (ρ=0.70 , p \<0.001) best correlating with change in DOMS. …”
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