Outcomes of Severe Sepsis and Septic Shock Patients on Chronic Antiplatelet Treatment: A Historical Cohort Study by Juan C. Valerio-Rojas, Insara J. Jaffer, Daryl J. Kor, Ognjen Gajic, Rodrigo Cartin-Ceba

Get full text

Hypothermia during Surgical Treatment of Type A Aortic Dissection: A 16 Years’ Experience by Francesco Macrina, Maria Cristina Acconcia, Luigi Tritapepe, Mizar D’abramo, Wael Saade, Alessandra Capelli, Fabio Miraldi

Get full text

Exploring Chronic Pain in Hemodialysis Patients: An Observational Study Based on the New IASP Classification for ICD-11 by Vittorio Schweiger, Martina Cacciapuoti, Marta Nizzero, Salvatore Simari, Gianmarco Lombardi, Leonardo Gottin, Lisa Stefani, Alvise Martini, Giustino Varrassi, Gabriele Finco, Enrico Polati, Giovanni Gambaro

Get full text

Evaluation of Non-Invasive Hemoglobin Monitoring in Perioperative Patients: A Retrospective Study of the Rad-67^TM (Masimo) by Philipp Helmer, Andreas Steinisch, Sebastian Hottenrott, Tobias Schlesinger, Michael Sammeth, Patrick Meybohm, Peter Kranke

Get full text

The Role of Rotational Thromboelastometry in Early Detection of the Hemostatic Derangements in Neonates with Systemic Candida Infection by Rozeta Sokou, Alexia Eleftheria Palioura, Aikaterini Konstantinidi, Alexandra Lianou, Maria Lampridou, Martha Theodoraki, Daniele Piovani, Stefanos Bonovas, Konstantina A. Tsante, Petros Ioannou, Nicoletta Iacovidou, Andreas G. Tsantes

“…Background: Systemic <i>Candida</i> infection (SCI) is the third most common cause of late-onset sepsis in Neonatal Intensive Care Units (NICU). While platelet involvement in fungal infections has been extensively studied, evaluation of the hemostatic mechanism in Candida infections, especially in neonates, has not been widely investigated. …”
Get full text

Correction: Surgical stabilization of rib fractures (SSRF): the WSES and CWIS position paper by Giacomo Sermonesi, Riccardo Bertelli, Fredric M. Pieracci, Zsolt J. Balogh, Raul Coimbra, Joseph M. Galante, Andreas Hecker, Dieter Weber, Zachary M. Bauman, Susan Kartiko, Bhavik Patel, SarahAnn S. Whitbeck, Thomas W. White, Kevin N. Harrell, Daniele Perrina, Alessia Rampini, Brian Tian, Francesco Amico, Solomon G. Beka, Luigi Bonavina, Marco Ceresoli, Lorenzo Cobianchi, Federico Coccolini, Yunfeng Cui, Francesca Dal Mas, Belinda De Simone, Isidoro Di Carlo, Salomone Di Saverio, Agron Dogjani, Andreas Fette, Gustavo P. Fraga, Carlos Augusto Gomes, Jim S. Khan, Andrew W. Kirkpatrick, Vitor F. Kruger, Ari Leppäniemi, Andrey Litvin, Andrea Mingoli, David Costa Navarro, Eliseo Passera, Michele Pisano, Mauro Podda, Emanuele Russo, Boris Sakakushev, Domenico Santonastaso, Massimo Sartelli, Vishal G. Shelat, Edward Tan, Imtiaz Wani, Fikri M. Abu-Zidan, Walter L. Biffl, Ian Civil, Rifat Latifi, Ingo Marzi, Edoardo Picetti, Manos Pikoulis, Vanni Agnoletti, Francesca Bravi, Carlo Vallicelli, Luca Ansaloni, Ernest E. Moore, Fausto Catena

Get full text

Tanshinone IIA Sodium Sulfonate Attenuates LPS-Induced Intestinal Injury in Mice by Xin-Jing Yang, Jin-Xian Qian, Yao Wei, Qiang Guo, Jun Jin, Xue Sun, Sheng-Lan Liu, Chun-Fang Xu, Guo-Xing Zhang

Get full text

Acute Kidney Injury Complicating Critical Forms of COVID-19: risk Factors and Prognostic Impact [version 3; peer review: 2 approved] by Ghadhoune Hatem, Yosra Yahia, Olfa Hammami, Hend Allouche, Insaf Trabelsi, Jihene Guissouma, Hana Ben Ali

“…Methods A retrospective descriptive case/control monocentric study conducted in a medical intensive care unit of a tertiary teaching hospital over a period of 18 months. …”
Get full text

Prostanoid Receptor Subtypes and Its Endogenous Ligands with Processing Enzymes within Various Types of Inflammatory Joint Diseases by Mohammed A. Al-Madol, Mohammed Shaqura, Thilo John, Rudolf Likar, Reham Said Ebied, Magdi M. Salih, Sascha Treskatsch, Michael Schäfer, Shaaban A. Mousa

Get full text

Parametrization of the dying brain: A case report from ICU bed-side EEG monitoring by Sebastian Zinn, Srdjan Z. Dragovic, Jan A. Kloka, Laurent M. Willems, Sebastian Harder, Stephan Kratzer, Kai D. Zacharowski, Gerhard Schneider, Paul S. García, Matthias Kreuzer

Get full text

Pharmacokinetic Characterisation and Comparison of Bioavailability of Intranasal Fentanyl, Transmucosal, and Intravenous Administration through a Three-Way Crossover Study in 24 He... by S. Nardi-Hiebl, J. W. Ndieyira, Y. Al Enzi, W. Al Akkad, T. Koch, G. Geldner, C. Reyher, L. H. J. Eberhart

“…While the intravenous formulation is primarily used for general anaesthesia and intensive care settings, the drug’s high lipophilic properties also allow various noninvasive routes of administration. …”
Get full text

LC-MS/MS assisted pharmacokinetic and tissue distribution study of ropivacaine and 3-OH-ropivacaine on rats after plane block anesthesia by Mihaela Butiulca, Mihaela Butiulca, Lenard Farczadi, Silvia Imre, Silvia Imre, Camil Eugen Vari, Laurian Vlase, Bogdan Cordos, Leonard Azamfirei, Leonard Azamfirei, Alexandra Elena Lazar, Alexandra Elena Lazar

Get full text

Opioid sparing anesthesia in patients with liver cirrhosis undergoing liver resection: a controlled randomized double-blind study by Eman Sayed Ibrahim, Ahmed A. Metwally, Mohamed Abdullatif, Essam A. Eid, Mahmoud G. Mousa, Amany A. Sultan

Get full text

Creatinine- and Cystatin C-Based Incidence of Chronic Kidney Disease and Acute Kidney Disease in AKI Survivors by Claire Rimes-Stigare, Bo Ravn, Akil Awad, Klara Torlén, Claes-Roland Martling, Matteo Bottai, Johan Mårtensson, Max Bell

“…A prospective cohort study was conducted in a Swedish intensive care unit (ICU) between 2008 and 2010. We included AKI patients alive at 90 days. …”
Get full text

Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

“…Abstract Background Pregnancy-associated atypical hemolytic uremic syndrome (aHUS) is a form of thrombotic microangiopathy (TMA) caused by uncontrolled activation of the complement system during pregnancy or the postpartum period. In the intensive care unit, aHUS must be differentiated from sepsis-related multiple organ dysfunction, thrombotic thrombocytopenic purpura (TTP), hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome. …”
Get full text

Downregulation of the immunoproteasome subunit PSMB8 attenuates sepsis-associated acute kidney injury through the NF-κB pathway by Min Li, Wenjia Tong, Chao Dai, Guoping Lu, Danqun Jin, Fang Deng

Get full text

Bortezomib-Induced Bronchiolitis Obliterans Organizing Pneumonia by E. Vandeix, F. Favard, N. Pichon, M. Delage-Corre, B. Melloni, M. Clavel

Get full text

Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency by Sílvia Bacalhau, Cristina Freitas, Rosalina Valente, Deolinda Barata, Conceição Neves, Katrin Schäfer, Annelie Lubatschofski, Ansgar Schulz, João Farela Neves

Get full text

Therapeutic Strategies for High-Dose Vasopressor-Dependent Shock by Estevão Bassi, Marcelo Park, Luciano Cesar Pontes Azevedo

“…Nearly 6% of critically ill patients will develop refractory shock, which accounts for 18% of deaths in intensive care unit. Mortality rates are usually greater than 50%. …”
Get full text

Fever and Shock in a Child: How 'good' is a Good Blood Test? by Nevin Kollannoor Chinnan, Pragnyadipta Mishra, GD Puri

“…After cardiac arrest, she was intubated and transferred to the intensive care unit. Two hours later, she started bleeding from the nasogastric tube and endotracheal tube. …”
Get full text