Development and validation of a nomogram model for prolonged length of stay in spinal fusion patients: a retrospective analysis by Linghong Wu, Xiaozhong Peng, Yao Lu, Cuiping Fu, Liujun She, Guangwei Zhu, Xianglong Zhuo, Wei Hu, Xiangtao Xie

“…Assessment of the models’ capability to improve classification efficiency was achieved using continuous net reclassification improvement (NRI) and integrated discrimination improvement (IDI). The Hosmer–Lemeshow method and calibration curve was utilised to assess the calibration degree, and decision curve to evaluate its clinical practicality. …”
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Elevated blood glucose and unfavourable tuberculosis treatment outcomes in a low-income setting: findings from a prospective cohort study in Eswatini by Diederick E Grobbee, Kerstin Klipstein-Grobusch, Kennedy Otwombe, Victor Williams, Alinda G Vos-Seda, Marianne Calnan, Colani S Ngwenya, Samson Haumba, Lindiwe Mdluli-Dlamini

“…Hypertension (AOR 4.84; 95% CI: 1.48, 15.7), unemployment (AOR 2.01; 95% CI: 1.08, 3.71) and high school education (AOR 0.32; 95% CI: 0.16, 0.64) were associated with unfavourable treatment outcome.Conclusion Our study shows the need to optimise care for patients receiving treatment for tuberculosis by integrating screening for and treatment of diabetes and hypertension, prioritising males, those aged ≥55 years and those with a reactive HIV status to limit unfavourable outcomes and death.…”
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Zero-BertXGB: An Empirical Technique for Abstract Classification in Systematic Reviews by Mohammad Shariful Islam, Mohammad Abu Tareq Rony, Md Rasel Hossain, Samah Alshathri, Walid El-Shafai

“…A novel Zero-BertXGB technique is introduced, integrating a transformer-based language model, zero-shot learning, and an ML classifier to enhance abstract screening and classification into “Include” or “Exclude” categories. …”
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MUC5B modulation of early oral biofilm glucose metabolism by Carolina Robertsson, Carolina Robertsson, Julia Davies, Gunnel Svensäter, Anders Bay Nord, Niclas Norrström, Claes Wickström

“…IntroductionSalivary mucin MUC5B has been suggested to support eubiosis in early oral biofilms by regulating the attachment of commensals, while downregulating dysbiotic activities related to dental caries development, such as microbial carbohydrate transport and metabolism.MethodsTo investigate how the metabolism of glucose, a potential driver for dental caries, in early mono- and dual-species biofilms of oral Actinomyces naeslundii and Streptococcus gordonii clinical isolates was affected by the presence of the complex salivary mucin MUC5B, this study employed nuclear magnetic resonance (NMR)-based metabolomics with the interpretation of network integration.Results and discussionMUC5B reduced early attachment in the presence of glucose compared with uncoated surfaces but maintained even species distribution. …”
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Exploring the Anti-PANoptosis Mechanism of Dachaihu Decoction Against Sepsis-Induced Acute Lung Injury: Network Pharmacology, Bioinformatics, and Experimental Validation by Yang Z, Kao X, Zhang L, Huang N, Chen J, He M

“…Zhen Yang,1,2 Xingyu Kao,1,2 Lin Zhang,3 Na Huang,1,2 Jingli Chen,2 Mingfeng He2 1The Eighth Clinical Medical College of Guangzhou University of Chinese Medicine, Foshan, Guangdong, People’s Republic of China; 2Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong, People’s Republic of China; 3Department of Cardiovascular, Integrated Hospital of Traditional Chinese Medicine, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence: Mingfeng He, Foshan Hospital of Traditional Chinese Medicine, Foshan, Guangdong, People’s Republic of China, Email he-mingfeng@foxmail.comBackground: Dachaihu decoction (DCHD) is a common Chinese medicine formula against sepsis-induced acute lung injury (SALI). …”
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Improving education for incarcerated children and young people: policy recommendations from three transnational projects in Europe by Adeela ahmed Shafi

“…From a practical perspective, these programmes and interventions have been designed to fit into existing structures and timetables with custodial and youth justice settings, making them easily integrated into business as usual. Originality/value – Planned and strategically delivered interventions by expert educators in a holistic way means there is real opportunity to better support justice involved children and young people to successful transitioning back into communities, thereby potentially reducing reoffending. …”
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Urinary human papillomavirus DNA as an indicator of gynaecological infection in young women in Schistosoma and HIV endemic South Africa by P. Pillay, H. N. Galappaththi-Arachchige, M. Taylor, B. Roald, B. Roald, E. F. Kjetland, E. F. Kjetland

“…There was no statistical association between urinary schistosomiasis and HPV or with any atypia.ConclusionUrine has the potential of being optimized as an alternative and possibly more acceptable sample for HPV detection among young adolescent populations at risk in comparison to CVL samples. An integrated targeted intervention incorporating Schistosoma in addition to HPV and HIV testing needs consideration among young women in this age group from endemic areas.…”
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Enhancing pathogens detection in suspected geriatric bloodstream infections using Nanopore-targeted sequencing by Menghui Zhao, Yan Ouyang, Junchi Mei, Hang Liu

“…This study highlights the need for further research to validate the routine clinical integration of NTS for managing BSIs in geriatric populations.IMPORTANCEBloodstream infections (BSIs) in elderly patients pose substantial diagnostic and therapeutic challenges due to the limitations of traditional blood culture methods, which are hampered by slow turnaround times and false-negatives. …”
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Irisin reshapes bone metabolic homeostasis to delay age-related osteoporosis by regulating the multipotent differentiation of BMSCs via Wnt pathway by Shangman Xing, Yifan Ma, Bing Song, Bing Song, Min Bai, Kexin Wang, Wenjing Song, Tingting Cao, Chao Guo, Yanying Zhang, Zhandong Wang, Yongfeng Wang, Yongfeng Wang

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Análisis constructivo y estructural de las baterías de costa en la playa La Chira (Perú) by Diego Javier Celis Estrada

“…Este estudio invita a la comunidad académica a explorar a fondo estas baterías de costa e insta a las autoridades culturales a actuar para preservarlas y reconocerlas oficialmente como parte integral del patrimonio del Perú. La falta de acción no solo arriesga la pérdida de estas estructuras históricas, sino también priva al país de una comprensión más completa de su pasado. …”
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Influence of Abutment Screw-Tightening Methods on the Screw Joint: Immediate and Long-Term Stability by Manlin Sun, Yusen Shui, Yuqiang Zhang, Ruiyang Ma, Yuwei Zhao, Hongyu Chen, Ping Yu, Zhi Li, Tingting Wu, Haiyang Yu

“…The operating time of method A was much longer than those of methods B and C (P<0.001). The structural integrity disruption of the screw thread was observed according to the SEM results in all postloading groups. …”
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Fabrication and In Vivo Evaluation of In Situ pH-Sensitive Hydrogel of Sonidegib–Invasomes via Intratumoral Delivery for Basal Cell Skin Cancer Management by Maha M. Ghalwash, Amr Gamal Fouad, Nada H. Mohammed, Marwa M. Nagib, Sherif Faysal Abdelfattah Khalil, Amany Belal, Samar F. Miski, Nisreen Khalid Aref Albezrah, Amani Elsayed, Ahmed H. E. Hassan, Eun Joo Roh, Shaimaa El-Housiny

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The Method of Situation Analysis of International Relations as A Forecasting Tool Under Conditions of Transforming World Order by V. G. Baranovsky, I. Ya. Kobrinskaya, S. V. Utkin, B. E. Frumkin

“…Its key innovation is understanding the international political situations under analysis as integral dynamic subsystems of international system. …”
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Vitamin D3/VDR alleviates double-stranded RNA virus -induced biliary epithelial cell damage by inhibiting autophagy by Na Liu, Pu Zhao, Ping Cao, JunPeng Hui, YongKang Pan, Jiwen Cheng

“…Vitamin D receptor (VDR) is thought to play a crucial role in maintaining the intrinsic immune balance and integrity of bile duct epithelial cells (BECs). To investigate the role of VDRs in the pathogenesis and progression of BA using in vitro and in vivo models. …”
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Schnittstellen zwischen performance und Analyse von Popmusik. Performative Produktionsprozesse in Pink Floyds Album Wish You Were Here und Jordan Rudessʼ Coverversion von Genesisʼ... by Hubertus Dreyer, Pascal Horn

“…. // The separation between a ‘work’ and its ‘interpretation’, which has been questioned in recent musical performance studies, is hardly applicable in pop music; performance (especially when it predominantly takes place in the studio) can be understood as an integral aspect of a song or album. The present article examines possible ‘interfaces’ between the analysis of performance and musical analysis of pop music. …”
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Genomic insights into ecological adaptation of oaks revealed by phylogenomic analysis of multiple species by Tian-Rui Wang, Xin Ning, Si-Si Zheng, Yu Li, Zi-Jia Lu, Hong-Hu Meng, Bin-Jie Ge, Gregor Kozlowski, Meng-Xiao Yan, Yi-Gang Song

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Using the WHO building blocks to examine cross-border public health surveillance in MENA by Laura Buback, Shayanne Martin, Esbeydy Pardo, Farah Massoud, Jesus Formigo, Atousa Bonyani, Noha H. Farag, Zayid K. Almayahi, Kenta Ishii, Susie Welty, Dana Schneider

“…Key challenges include delayed and incomplete data sharing, insufficient funding across sectors, inadequate training, inconsistent data definitions, and limited integration of health data for mobile populations. Recommendations emphasize strengthened governance and leadership to facilitate regional cooperation and information sharing, sustainable financing for implementing a One Health approach, utilizing innovative information systems, workforce development to enhance data collection and analysis, and secure supply chains for medicines and vaccines and equitable service delivery for all mobile populations. …”
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Collection and Determination of Clinical Problems and Outcome Indicators of Expert Consensus on Clinical Application of Ethnic Medicine in the Treatment of Palpitation (Arrhythmia-... by ZHANG Wenjie, LI Jun, CHEN Hengwen, TAN Yuqing, XIE Zicong, WU Ji, MENG Chao, LI Zhaoling, ZHANG Lesong

“…In April 2023, a series of one-on-one online interviews were conducted with 14 multi-ethnic medical experts. Following the integration of the interview results and expert experiences, the consensus steering committee and working group jointly drafted the initial proposals for clinical questions and outcome indicators, subsequently designing a survey questionnaire. …”
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Application of humanistic care for patients with abdominal aortic aneurysm (人文关怀护理在腹主动脉瘤患者中的应用) by WANG Qianqian (王倩倩), QI Jiaxin (齐加新), JIANG Zhenzhen (蒋真真)

“…Conclusion Humanistic care nursing and psychological counseling is implemented in AAA patients, which realizes the perfect combination of psychosomatic nursing, provides patients with satisfactory humanistic medical experience, increases patients’ treatment compliance and treatment effect, improves patients’ quality of life, and promotes patients’ early recovery and community integration. (目的 探讨人文关怀护理在腹主动脉瘤(AAA)患者中的应用效果。方法 79例AAA患者根据病区分为对照组38例和研究组41例。…”
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Safeguarding in Sport: The Performative Compliance of International Sports Federations by Carole Gomez, Lucie Schoch

“…Moreover, safeguarding is frequently conflated with broader integrity issues. Discussion/Conclusion In response to external pressures and heightened expectations from stakeholders, IFs—guided by IOC—have actively crafted policies aimed at athlete protection. …”
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