Defining ecological thresholds to detect potential ecological risks of offshore wind power using macrobenthic biodiversity and indicator species in Cangnan, China by Wanhong Han, Chen Song, Yurong Zhang, Weiwei Zhou, Yushu Yang, Danyi Ke, Aoxiang Huang, Xiaobo Wang, Qingxi Han

“…Therefore, investigating the responses of macrobenthic diversity to the development and operation of wind farms and establishing ecological thresholds is crucial for safeguarding benthic ecological quality and promoting the sustainable development of offshore wind energy. To integrate the concept of ecological thresholds with empirical assessments to identify critical environmental limits for sustainable management, macrobenthic samples and water environmental factors were collected from 2021 to 2023 in the Cangnan offshore wind power area and an adjacent control area. …”
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Modeling Marine Geoid in the China Seas and Its Adjacent Ocean Based on Satellite Altimeter-Derived Gravity Anomaly Model by Huiying Zhang, Xin Liu, Zhen Li, Xiaotao Chang, Heping Sun, Hui Li, Jinyun Guo

“…The SDUST2022 GRA marine gravity anomaly model is the global marine gravity anomaly model constructed by integrating multi-source altimeter satellites, including ICEsat-2 laser altimeter satellite for the first time. …”
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Measuring Empathy among Dental Students and Interns: A Cross-Sectional Study from Dammam, Saudi Arabia by Muhammad Nazir, Muhanad Alhareky, Abdulrahman Alqahtani, Leenah Alsulaimi, Reema Alotaibi, Najwa Yousef, Fatimah Abushal, Jehan Alhumaid

“…Female gender, high GPA, and class years were associated with empathy. Empathy should be integrated into dental curricula for effective student learning and positive patient care outcomes.…”
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Metabolomic and proteomic profiling of a burn-hemorrhagic shock swine model reveals a metabolomic signature associated with fatal outcomes by Bin Wei, Jinguang Zheng, Jiake Chai, Jianxiang Huang, Hongjie Duan, Shaofang Han, Xiaolin Yang, Wenjia Zhang, Fangchao Hu, Yirui Qu, Xiangyu Liu, Tian Liu, Yushou Wu, Yunfei Chi

“…The metabolomic and proteomic data were processed through partial least squares–discriminant analysis (PLS–DA) and the KEGG enrichment etc. Furthermore, the integrate analysis of the metabolomic and proteomic data was generalized by canonical correlation discriminant analysis, and the correlation between metabolites and mortality of the swine model was predicted using a multiple linear regression model by Pearson analysis. …”
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Qualitative evaluation of the Rehabilitation Exercise and psycholoGical support After COVID-19 InfectioN (REGAIN) randomised controlled trial (RCT): ‘you are not alone’ by Gordon McGregor, Susanne Finnegan, Martin Underwood, Joyce Yeung, James Mason, Peter Heine, Nigel Edwards, Julie Bruce, Kate Seers, Harbinder Kaur Sandhu, Helen Atherton, Sharisse Alleyne, Katie Booth, Ranjit Lall, Vivien P Nichols, Stuart Ennis, Scott McGuire, Rachel Potter, Jessica Smith, Chen Ji, Shilpa Patel, Henry Nwankwo, Kate Evans, Susie Hennings, Alastair Canaway, Grace Lobley, David Mcwilliams, Christina Jones, Emma Padfield, David Montgomery, Beatriz Lara, Becky Haley, Francesca Denton, Bartholomew Sheehan, Mariam Ratna, Elaine Fairbrother, Zoe Noakes, Bogdan Zutic, Lee Austin, Tom Forsyth, Anne Bush, Alan Bush, Patrick Sawdon, Jonathon Prosser, Lee Tompkins, Jonathon Guck, Danielle Hale, Juwairia Said, Georgie Ray, Rowena Williams, Gail Evans, Thillini Hettiarachchi, Abeesh Panicker

“…Framework and thematic analysis were used to analyse the findings.Setting England and Wales, UK.Participants Adults discharged from National Health Service (NHS) hospitals at least 3 months previously after COVID-19, with ongoing physical and/or mental health sequelae.Results Twenty intervention participants, 20 control participants and five practitioners were interviewed.The themes from the group support sessions were: (1) you are not alone; (2) sharing experiences and addressing worries; (3) gaining new perspectives; (4) hope for progression; (5) peer support and bonding; (6) integration of facilitation skills; (7) modified activity pacing and goal setting, and (8) giving participants structure. …”
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A simple and efficient method to extract polar metabolites from guar leaves (Cyamopsis tetragonoloba (L.) Taub.) for GC-MS metabolome analysis by S. B. Teplyakova, A. L. Shavarda, T. V. Shelenga, E. A. Dzyubenko, E. K. Potokina

“…Thus, leaf tissues retain morphological integrity, and subsequent centrifugation, necessary for homogenization, is skipped. …”
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Use of inpatient palliative care in metastatic testicular cancer patients undergoing critical care therapy: insights from the national inpatient sample by Cristina Cano Garcia, Reha-Baris Incesu, Francesco Barletta, Simone Morra, Lukas Scheipner, Andrea Baudo, Stefano Tappero, Mattia Luca Piccinelli, Zhe Tian, Fred Saad, Shahrokh F. Shariat, Carlo Terrone, Ottavio De Cobelli, Luca Carmignani, Sascha Ahyai, Nicola Longo, Derya Tilki, Alberto Briganti, Severine Banek, Luis A. Kluth, Felix K. H. Chun, Pierre I. Karakiewicz

“…This could enhance the integration of IPC in the treatment of advanced cancer, potentially improving quality of life and care outcomes for survivors.…”
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Impact of pharmacist-led educational intervention on knowledge of self-management among asthmatic patients: a prospective cohort study by Ahmad Khan, Saima Mushtaq, Amjad Khan, Nafees Ahmad, Shahzadi Sidra Saleem, Rubina Aman, Shahzadi Sadia Saleem, Ayesha Bibi, Saifullah Mehsud, Ivan R Green, Sheikh Abdur Rashid, Kifayat Ullah Shah

“…This would suggest that education and self-management skills should be seen as an integral component of asthma management and should be incorporated in structured patient care to achieve optimal asthma control.…”
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Solar Energy Forecasting Framework Using Prophet Based Machine Learning Model: An Opportunity to Explore Solar Energy Potential in Muscat Oman by Mazhar Baloch, Mohamed Shaik Honnurvali, Adnan Kabbani, Touqeer Ahmed, Sohaib Tahir Chauhdary, Muhammad Salman Saeed

“…In this research, different models, named Linear Regression (LR), Support Vector Machine (SVR), KNN Regressor, Decision Forest Regressor, XGBoost Regressor, Neural Network (NN), Autoregressive Integrated Moving Average (ARIMA), Long Short-Term Memory (LSTM), Random Forest Regressor, Categorical Boosting (CatBoost), Deep Autoregressive (DeepAR), and Facebook Prophet, are trained and tested under both identical features and a training–testing ratio. …”
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Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model by Xing Tu, Zixing Zou, Jiahui Li, Simiao Zeng, Zhengchao Luo, Gen Li, Yuanxu Gao, Kang Zhang, Jing Ni

“…Our research indicates that all five candidates recommended by AI were able to protect the morphological integrity of RGC cells when exposed to hypoxia and glucose deficiency, and HG9-91-01 showed a higher cell survival rate compared to the other candidates. …”
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Clinical Characteristics of Virologically Confirmed Respiratory Syncytial Virus in English Primary Care: Protocol for an Observational Study of Acute Respiratory Infection by Uy Hoang, Utkarsh Agrawal, José Manuel Ordóñez-Mena, Zachary Marcum, Jennifer Radin, Andre Araujo, Catherine A Panozzo, Orsolya Balogh, Mihir Desai, Ahreej Eltayeb, Tianyi Lu, Catia Nicodemo, Xinchun Gu, Rosalind Goudie, Xuejuan Fan, Elizabeth Button, Jessica Smylie, Mark Joy, Gavin Jamie, William Elson, Rachel Byford, Joan Madia, Sneha Anand, Filipa Ferreira, Stavros Petrou, David Martin, Simon de Lusignan

“…In addition to using the POCT device, we provide suggestions about how to integrate POCT into primary care workflow and templates for high-quality data recording of diagnosis, symptoms, and signs. …”
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User-Oriented Requirements for Artificial Intelligence–Based Clinical Decision Support Systems in Sepsis: Protocol for a Multimethod Research Project by Pascal Raszke, Godwin Denk Giebel, Carina Abels, Jürgen Wasem, Michael Adamzik, Hartmuth Nowak, Lars Palmowski, Philipp Heinz, Silke Mreyen, Nina Timmesfeld, Marianne Tokic, Frank Martin Brunkhorst, Nikola Blase

“…The findings of this research project have the potential to facilitate the integration of AI-based CDSS into standard care in the long term. …”
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Clinical and genetic drivers of oligo-metastatic disease in colon cancer by Alessandro Ottaiano, Mariachiara Santorsola, Roberto Sirica, Annabella Di Mauro, Antonella Di Carlo, Monica Ianniello, Francesco Sabbatino, Rosa Castiello, Francesca Del Peschio, Marco Cascella, Francesco Perri, Maurizio Capuozzo, Nicola Martucci, Edoardo Mercadante, Valentina Borzillo, Rossella Di Franco, Francesco Izzo, Vincenza Granata, Carmine Picone, Antonella Petrillo, Massimiliano Berretta, Salvatore Stilo, Luca Tarotto, Anna Chiara Carratù, Gerardo Ferrara, Madhura Tathode, Alessia Maria Cossu, Marco Bocchetti, Michele Caraglia, Guglielmo Nasti, Giovanni Savarese

“…OMD patients exhibited distinct molecular characteristics, including lower frequencies of BRAF p.V600E (P=0.0315) and KRAS mutations (P=0.0456), as well as a higher frequency of high tumor mutational burden (P=0.0127). Additionally, by integrating data from public datasets and our case study, we hypothesize that some gene alterations (i.e.: BRAF, SMAD4, RAF1, and mTOR) may prevent OMD occurrence. …”
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Development of improved deep learning models for multi-step ahead forecasting of daily river water temperature by Mehdi Gheisari, Jana Shafi, Saeed Kosari, Samaneh Amanabadi, Saeid Mehdizadeh, Christian Fernandez Campusano, Hemn Barzan Abdalla

“…This study addresses the limited use of signal decomposition in hybrid WT prediction models by proposing three methods: namely ensemble empirical mode decomposition (EEMD) on AdaBoost, long short-term memory (LSTM), and gated recurrent unit (GRU). These models integrate ensemble empirical mode decomposition (EEMD) with machine learning techniques for forecasting WT across multiple time horizons (one, three, and five days). …”
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Saberes forestales y cambio climático en cacao (Theobroma cacao), majo (Oenocarpus bataua) y asaí (Euterpe precatoria), en el norte de La Paz by Yuri Sandoval-Montes, Javier Nuñez Villalba, Carla Machicado Sanchez, Leonardo Cabrera

“…Para ello, se llevó a cabo la recopilación de información mediante encuestas a 119 pobladores locales en el marco del proyecto Manejo Integral y Bioconservación Ambiental de Frutos del Bosque en el Norte Amazónico del Departamento de La Paz (Fase 1), financiado por FONABOSQUE para la gestión 2022-2024. …”
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Tear glucose is associated with the presence and severity of diabetic retinopathy by Ningyao Cao, Lili Feng, Wei Xu, Fanglin He, Caiwen Xiao, Yan Liu, Weirong Xu, Jingjing Cui, Yuqian Guo, Lianqing Yao, Wenwen Xia, Fei Chen, Yong Li, Chuandi Zhou, Xiaofang Xu

“…The area under the curve (AUC) of the model integrating TG, the duration of diabetes and HbA1c was 0.76 (95% CI 0.69–0.84), indicating a fair discriminative ability of DR. …”
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Single-cell RNA sequencing and immune microenvironment analysis reveal PLOD2-driven malignant transformation in cervical cancer by Zhiheng Lin, Fengxin Wang, Renwu Yin, Shengnan Li, Yuquan Bai, Baofang Zhang, Chenlin Sui, Hengjie Cao, Dune Su, Lianwei Xu, Honghong Wang

“…The validation of PLOD2 as a prognostic gene highlights its therapeutic potential, underscoring the critical need for integrating immunotherapy and targeted treatment strategies to enhance diagnostic and therapeutic approaches in cervical cancer.…”
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Assessing the determinants of out-of-pocket health expenditures among Cambodian households in informal employment using survey data by Andrea Hannah Kaiser, Sovathiro Mao, Jesper Sundewall, Marlaina Ross, Sokunthea Koy, Searivoth Vorn, Pichenda Koeut, Bjoern Ekman

“…Conclusions Our findings emphasize the necessity of integrating nonpoor informal workers and their dependents into formal prepayment schemes to reduce OOPE and enhance financial protection on Cambodia’s path toward universal health coverage. …”
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Efficacy, safety, and biomarker analysis of TACE combined with lenvatinib plus sintilimab in unresectable hepatocellular carcinoma: a real-world study by Lingzhan Meng, Hu Li, Yingjie Ji, Peng Yu, Zizheng Wang, Li Cao, Bin Shi, Yanling Shao, Jin Yan, Yinjie Gao, Zhenyu Zhu

“…Abstract Background The integration of transarterial chemoembolization (TACE) with systemic therapy has demonstrated improved survival outcomes in patients with unresectable hepatocellular carcinoma (HCC). …”
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Dependence of Water Vapour Adsorption on the Polarity of the Graphene Surfaces of Multi-Wall Carbon Nanotubes by Robert H. Bradley, Aurik Andreu, Kelby Cassity, Susan Osbeck, Rodney Andrews, Mark Meier, Colin Johnston

“…These values also reflect the difference in the integral net enthalpies of adsorption for the two hydrophilic surfaces: a value of ca. −35 mJ/m 2 being obtained for an oxygen-free (hydrophobic) surface. …”
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