Obesity, Metabolic Health, and Diabetic Complications in People With Type 1 Diabetes by Yuanjie Mao, Jen‐Tzer Gau, Ning Jiang

“…Materials and Methods Insulin resistance was calculated by estimated glucose disposal rate (eGDR). …”
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Determination of Irisin, Body Mass Index, and Other Biochemical Parameters in a Sample of Iraqi Type II Diabetic Patients by Takwa Al Koloob Ali Chachan, Huda Farhan, Shatha Hamed

“… Evidence suggests that Irisin, a peptide hormone, may play a role in lipid metabolism, insulin resistance, and obesity. On the other hand, its role in type 2 diabetic Mellitus [T2DM] in humans is uncertain. …”
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C-Peptide: A New Mediator of Atherosclerosis in Diabetes by Dusica Vasic, Daniel Walcher

“…Diabetes type 2 and insulin resistance are the risk factors for cardiovascular disease. …”
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Hypercysteinemia, A Potential Risk Factor for Central Obesity and Related Disorders in Azores, Portugal by Ana Lima, Rita Ferin, Mafalda Bourbon, José Baptista, M. Leonor Pavão

“…Moreover, plasma Cys levels predicted waist circumference (β coefficient = 0.102, P=0.032) and concomitant central obesity and were also associated with insulin resistance. Nevertheless, hyperhomocysteinemia prevalence was similar in both groups, despite the fact that PDL subjects exhibited a higher rate of vitamin B12 deficiency compared to those from Lisbon (19% vs. 6%, P=0.003). …”
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Treatment with Lobeglitazone Attenuates Hepatic Steatosis in Diet-Induced Obese Mice by Sorim Choung, Kyong Hye Joung, Bo Ram You, Sang Ki Park, Hyun Jin Kim, Bon Jeong Ku

“…Nonalcoholic fatty liver disease (NAFLD) is strongly associated with insulin resistance. The peroxisome proliferator-activated receptor (PPAR) activators, thiazolidinediones, (TZDs), are insulin sensitizers used as a treatment for NAFLD. …”
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Effect of weight loss on the course of non-alcoholic fatty liver disease: results of 6-month follow-up by L. V. Chesnokova, I. M. Petrov, I. A. Troshina, M. V. Goncharova, I. V. Medvedeva

“…Weight loss for 5% and over at steatosis stage of NAFLD is characterized by decrease ofbiochemical cardio-vascular risk markers, in addition the group with 40 min/day physical exercises inefficacy had lower level of insulin resistance index and TNF-α along with higher levels of NO metabolites.…”
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Assessment of Zinc Alpha-2 Glycoprotein Level in Gestational Diabetes Woman in Respect to Glycemic Status with and without Treatment by Bara Nahdh Saleem, Manal Khalid Abdulridha, Hind Abdalkhaliq Showman, Manal Sabbar

“…It is distinguished by substantial insulin resistance induced by the secretion of placental hormone. …”
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Triglyceride Glucose Index Was a Predictor of 6-Month Readmission Caused by Pulmonary Infection of Heart Failure Patients by Licheng Shi, Jianan Liu, Xuanfeng Zhu, Tiantian Li, Jingli Wen, Xinyu Wang, Xu Qi

“…Objectives. Insulin resistance is associated with the prognosis of heart failure (HF) patients. …”
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Implications of the Intestinal Microbiota in Diagnosing the Progression of Diabetes and the Presence of Cardiovascular Complications by Alina Mihaela Leustean, Manuela Ciocoiu, Anca Sava, Claudia Florida Costea, Mariana Floria, Claudia Cristina Tarniceriu, Daniela Maria Tanase

“…Key factors that cause cardiovascular disease in people with diabetes include hyperglycemia, dyslipidemia, obesity, insulin resistance, inflammation, hypertension, autonomic dysfunction, and decreased vascular response capacity. …”
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L-Arginine Supplementation in Type II Diabetic Rats Preserves Renal Function and Improves Insulin Sensitivity by Altering the Nitric Oxide Pathway by Taylor Claybaugh, Sarah Decker, Kelly McCall, Yuriy Slyvka, Jerrod Steimle, Aaron Wood, Megan Schaefer, Jean Thuma, Sharon Inman

“…These results suggest the importance of the NO pathway in consequent renal dysfunction and in the development of insulin resistance in diabetic rats.…”
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Chronic Glucocorticoid-Rich Milieu and Liver Dysfunction by Hernán Gonzalo Villagarcía, Vanesa Sabugo, María Cecilia Castro, Guillermo Schinella, Daniel Castrogiovanni, Eduardo Spinedi, María Laura Massa, Flavio Francini

“…In conclusion adult MSG rats developed an insulin-resistant state and increased OS and serious hepatic dysfunction characterized by inflammation and metabolic signs suggesting increased lipogenesis. …”
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Protective Role of Picralima nitida Seed Extract in High-Fat High-Fructose-Fed Rats by Opeyemi Christianah De Campos, Daniel Ikpomwosa Osaigbovo, Titilayo Ifeoluwa Bisi-Adeniyi, Franklyn Nonso Iheagwam, Solomon Oladapo Rotimi, Shalom Nwodo Chinedu

“…APN caused a significant decrease (P<0.05) in weight gained, body mass index, insulin resistance, plasma glucose, and insulin levels. …”
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Metabolic Profile in a Cohort of Young Sicilian Patients with Klinefelter’s Syndrome: The Role of Irisin by Stefano Radellini, Valentina Guarnotta, Vincenzo Sciabica, Giuseppe Pizzolanti, Carla Giordano

“…Irisin blood levels of Klinefelter’s patients are higher than in healthy subjects and positively correlate with the degree of insulin resistance.…”
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Role of NKT Cells in the Pathogenesis of NAFLD by Kazuto Tajiri, Yukihiro Shimizu

“…NKT cells may have a protective role at the early stage with simple steatosis through modification of insulin resistance, whereas they act as a progression factor at the advanced stage with fibrosis. …”
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Thiazolidinediones and Fertility in Polycystic Ovary Syndrome (PCOS) by Pascal Froment, Philippe Touraine

“…The positive action of the insulin-sensitizing treatments could be explained by a decrease in the peripheral insulin resistance but also by a direct action at the ovarian level. …”
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Utilization of edible poultry slaughter residues: A chicken-liver hydrolysate with glucose-lowering ability and upregulating glycogenesis in type II diabetes by Yi-Ling Lin, Yu-Pei Chen, Sheng-Yao Wang, Yi-Feng Kao, Chompunut Lumsangkul, Yi-Chen Chen

“…In db/db mice, CLH supplementation improved insulin resistance, as shown by OGTT assay, HOMA-IR value and serum glucose levels, while also reducing serum lipids and liver damage indices (p<0.05). …”
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Pre-diabetes and cardiovascular risk factors in NAFLD patients: a retrospective comparative analysis by Azam Teimouri, Zahra Ebrahimpour, Awat Feizi, Bijan Iraj, Elahe Saffari, Mojtaba Akbari, Mozhgan Karimifar

“…ObjectivesInsulin resistance plays a critical role in the pathophysiology of diabetes mellitus and non-alcoholic fatty liver disease (NAFLD). …”
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The Use of SGLT-2 Inhibitors and GLP-1RA in Frail Older People with Diabetes: A Personalised Approach Is Required by Alan J. Sinclair, Ahmed H. Abdelhafiz

“…The frailty syndrome appears to span across a spectrum, from a sarcopenic obese phenotype at one end, characterised by obesity, insulin resistance, and prevalent cardiovascular risk factors, to an anorexic malnourished phenotype at the other end, characterised by significant weight loss, reduced insulin resistance, and less prevalent cardiovascular risk factors. …”
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Adipocyte DIO2 Expression Increases in Human Obesity but Is Not Related to Systemic Insulin Sensitivity by David Bradley, Joey Liu, Alecia Blaszczak, Valerie Wright, Anahita Jalilvand, Bradley Needleman, Sabrena Noria, David Renton, Willa Hsueh

“…Our results suggest that adipocyte-derived DIO2 may play a role in weight maintenance but is likely not a major contributor to obesity-related insulin resistance.…”
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Classic and Novel Sex Hormone Binding Globulin Effects on the Cardiovascular System in Men by Carla Basualto-Alarcón, Paola Llanos, Gerardo García-Rivas, Mayarling Francisca Troncoso, Daniel Lagos, Genaro Barrientos, Manuel Estrada

“…Circulating SHBG levels are influenced by metabolic and hormonal factors, and they are reduced in obesity and insulin resistance, suggesting that SHBG may have a broader clinical utility in assessing the risk for cardiovascular diseases. …”
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