The highly prolific phenotype of Lacaune sheep is associated with an ectopic expression of the B4GALNT2 gene within the ovary. by Laurence Drouilhet, Camille Mansanet, Julien Sarry, Kamila Tabet, Philippe Bardou, Florent Woloszyn, Jérome Lluch, Grégoire Harichaux, Catherine Viguié, Danielle Monniaux, Loys Bodin, Philippe Mulsant, Stéphane Fabre

“…The reduced FecL locus contained only two genes, insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) and beta-1,4-N-acetyl-galactosaminyl transferase 2 (B4GALNT2), and we identified two SNP in complete linkage disequilibrium with FecL(L) . …”
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Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy by Yiji Tu, Zenggan Chen, Feng Zhang, Zhenglin Di, Junhui Zhang, Li Cai

“…DEGs from the 3 most highly connected clusters in the protein-protein interaction network were enriched for biological processes or pathways such as “cell division,” “cell cycle,” “protein phosphorylation,” “chemokine signaling pathway,” “neuropeptide signaling pathway,” “response to drug,” “cellular response to insulin stimulus,” “PPAR signaling pathway,” and “glycerophospholipid metabolism.” …”
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Detection and Quantification of the Relationship between the Ratio of Triglycerides over High-Density Lipoprotein Cholesterol and the Level of Serum Uric Acid: One Cross-Sectional... by Yuexi Li, Yuhan Luo, Qiaoli Wang, Xiaoqin Liu

“…It was previously reported that the ratio of triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) is not only an important marker of cardiovascular disease, stroke, atherosclerosis, and insulin resistance but is also associated with an elevated level of serum uric acid. …”
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Strategies to reduce hyperglycemia-related anxiety in elite athletes with type 1 diabetes: A qualitative analysis. by Alexandra Katz, Aidan Shulkin, Marc-André Fortier, Jane E Yardley, Jessica Kichler, Asmaa Housni, Meryem K Talbo, Rémi Rabasa-Lhoret, Anne-Sophie Brazeau

“…These strategies include managing insulin and nutrition intake, embracing social support networks, using technology, practicing relaxation techniques, establishing routines, performing pre-competition aerobic exercise, and maintaining adequate sleep hygiene. …”
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Promoting Immortalized Adipose-Derived Stem Cell Transdifferentiation and Proliferation into Neuronal-Like Cells through Consecutive 525 nm and 825 nm Photobiomodulation by Madeleen Jansen van Rensburg, Anine Crous, Heidi Abrahamse

“…Cells were exposed to induction type 1 (IT1): 3-isobutyl-1-methylxanthine (IBMX) (0.5 mM)+indomethacin (200 μM)+insulin (5 μg/ml) for 14 days, preinduced with β-mercaptoethanol (BME) (1 mM) for two days, and then incubated with IT2: β-hydroxyanisole (BHA) (100 μM)+retinoic acid (RA) (10-6 M)+epidermal growth factor (EGF) (10 ng/ml)+basic fibroblast growth factor (bFGF) (10 ng/ml) for 14 days and preinduced with β-mercaptoethanol (BME) (1 mM) for two days and then incubated with indomethacin (200 μM)+RA (1 μM)+forskolin (10 μM) for 14 days. …”
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Effect of probiotic-fermented milk containing Lactiplantibacillus pentoses strain HBUAS 53657 on serum glutathione peroxidase activity and pancreatic histopathology in hyperglycemi... by Rita Yaswir, Eti Yerizel, Netti Suharti, Cimi Ilmiawati

“… Background: Hyperglycemia is characterized by elevated blood glucose levels caused by impaired insulin production or function, leading to oxidative stress. …”
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A Critical Review of Proteomic Studies in Gestational Diabetes Mellitus by Tao Zhou, Lu Huang, Min Wang, Daozhen Chen, Zhong Chen, Shi-Wen Jiang

“…Functional analysis of all the combined significant proteins also showed that a small number of proteins are known to be involved in the regulation of insulin or indirect signaling pathways. However, many factors such as diagnostic criteria, sample processing, proteomic method, and statistical method can greatly affect the identification of reproducible and reliable protein candidates. …”
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Blood-based biomarkers in mild behavioral impairment: an updated overview by Efthalia Angelopoulou, Xenia Androni, Chiara Villa, Alexandros Hatzimanolis, Nikolaos Scarmeas, Sokratis Papageorgiou

“…In this context, MBI has been associated with lower plasma Aβ42/Αβ40 ratio, higher plasma phosphorylated tau at threonine 181 (p-tau181), increased neurofilament light chain (NfL) levels, as well as disturbances in metabolic markers, including homocysteine, insulin and ferritin, suggesting a multifaceted neurobiological basis for this syndrome. …”
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Regulation of Hypoxia-Induced Cell Death in Human Tenocytes by Min Liang, Hannah R. Cornell, Nasim Zargar Baboldashti, Mark S. Thompson, Andrew J. Carr, Philippa A. Hulley

“…As a protective strategy for tenocytes at risk of hypoxic death we added prosurvival growth factors insulin or platelet rich plasma (PRP). Both agents strongly protected tenocytes from hypoxia-induced death over 48 h, suggesting possible efficacy in the acute postrupture tendon or integrating graft.…”
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Evaluation of Adiponectin Hormone and its Gene Polymorphism in Obese Women with Polycystic Ovary Syndrome by Naznaz Othman, Kalthum Maulood, Suhaila Darogha

“…Results showed that adiponectin levels in PCOS decreased significantly, while leptin increased significantly when compared to control. HOMA-IR, Glucose, Insulin, and Testosterone parameters increased significantly in PCOS, while SHBG increased non-significantly. …”
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Intelligent Ensemble Deep Learning System for Blood Glucose Prediction Using Genetic Algorithms by Dae-Yeon Kim, Dong-Sik Choi, Ah Reum Kang, Jiyoung Woo, Yechan Han, Sung Wan Chun, Jaeyun Kim

“…To this end, this study proposes an intelligent ensemble deep learning system to predict BG values in 15, 30, and 60 min prediction horizons (PHs) based on historical BG values collected via continuous glucose monitoring devices as an endogenous factor and carbohydrate intake and insulin administration information (times) as exogenous factors. …”
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Transcriptomic signatures of subcutaneous adipose tissue in patients with diabetes and coronary artery disease: a pilot study by Ilias P. Doulamis, Bernard Pan, Aspasia Tzani, Jorge Plutzky, G. William Wong, Ahmet Kilic, Risa M. Wolf

“…SPI1 and MTF1 were two novel upstream transcription factors identified which have been suggested to be involved in the inflammatory cascade and insulin regulation in diabetes. Three miRNAs were differentially expressed between the two groups (miR-27a, miR-335 and miR-146). …”
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Impact of maternal prenatal stress by glucocorticoids on metabolic and cardiovascular outcomes in their offspring: A systematic scoping review. by Claudia Eberle, Teresa Fasig, Franziska Brüseke, Stefanie Stichling

“…However, maternal risk factor "stress", is clearly linked to adverse cardio-metabolic offspring outcomes, postnatally, such as obesity, hyperglycemia, insulin resistance, diabetes mellitus (DM), Metabolic Syndrome (MetS), cardiovascular disease (CD), hypertension, restricted fetal growth as well as reduced birth, adrenal, and pancreas weights.…”
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The Angiotensin-Melatonin Axis by Luciana A. Campos, Jose Cipolla-Neto, Fernanda G. Amaral, Lisete C. Michelini, Michael Bader, Ovidiu C. Baltatu

“…On the other hand, since melatonin is capable of ameliorating metabolic abnormalities in DM and insulin resistance, the beneficial effects of RAS blockade could be improved through combined RAS blocker and melatonin therapy. …”
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Excessive Weight Gain During Pregnancy Increased Ponoxarase 1 Level in Neonatal Cord Blood by Serhat Ege, Hasan Akduman, Ayşegül Aşır, Tuğcan Korak

“…Functional annotation analysis revealed significant enrichment in antioxidant and oxidoreductase activities, along with pathways involved in insulin resistance, AGE-RAGE signaling, and atherosclerosis. …”
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Impact of Hospitalization on Continuation of SGLT2 Inhibitors and GLP-1 Receptor Agonists for Comorbidities in Patients with Type 2 Diabetes by Bethany Murphy, Simran Chahal, Elleigh Shepherd, Nicole Taylor, Austin Camp

“…Because guidelines typically recommend insulin for inpatient treatment of T2DM, there is potential these therapies may be negatively impacted by hospitalization. …”
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Prospects of betulin application in broiler farming by M. V. Novikova, I. A. Lebedeva, L. I. Drozdova, A. V. Byuler

“…Histological studies of pancreatic tissue samples from broiler chickens showed increase in the mass of islets of Langerhans and insulin-producing cell complexes. The pancreas was activated due to effects of the betulin-based feed additive. …”
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Review: cell mechanisms in the control of inflammatory foundations of obesity and secondary metabolic disorders by Kristin Goldstone, Keelin Irwin, Ava O' Meara-Cushen, Cathy Brougham

“…Obesity-related inflammation can precipitate several diseases, such breast cancer, insulin resistance, type II diabetes and cardiovascular issues. …”
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Integrated transcriptome and metabolome analysis of liver reveals unsynchronized growth mechanisms in blunt-snout bream (Megalobrama amblycephala) by Qi Liu, Xue Zou, Ming Zhao, Qianqian Guan, Zhaoyang Xuan, Lusha Liu, Zexia Gao

“…KEGG and GO enrichment analysis indicated that the DEGs with higher expression level were significantly correlated with insulin signaling pathway, steroid hormone and lipid metabolism related pathway (PPAR signaling pathway and fatty acid degradation). …”
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Sex, Prescribing Practices and Guideline Recommended, Blood Pressure, and LDL Cholesterol Targets at Baseline in the BARI 2D Trial by Michelle F. Magee, Jacqueline E. Tamis-Holland, Jiang Lu, Vera A. Bittner, Maria Mori Brooks, Neuza Lopes, Alice K. Jacobs, BARI 2D Study Group

“…Women were less frequent on metformin or sulfonylurea and more likely to take insulin and to be on higher doses of hydroxymethylglutaryl-CoA reductase inhibitors (statins) than men. …”
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