The Effect of Telenursing on Disease Outcomes in People with Type 2 Diabetes Mellitus: A Narrative Review by Mina AkbariRad, Mohsen Dehghani, Masoumeh Sadeghi, Ashkan Torshizian, Nikoo Saeedi, Mehrdad Sarabi, Mahdieh Sahebi, Mohammad Taghi Shakeri

“…Increasing patients’ knowledge about their drugs, insulin administration, and diabetes complications improves self-care behaviors and medical adherence. …”
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Evaluation of machine learning-based regression techniques for prediction of diabetes levels fluctuations by Badriah Alkalifah, Muhammad Tariq Shaheen, Johrah Alotibi, Tahani Alsubait, Hosam Alhakami

“…Unfortunately, these methods require the patient to identify their daily activities, which can be error-prone, such as meal intake, insulin injection, and emotional aspects. This paper suggests using continuous glucose monitoring (CGM) of 14733 patients, with three assistance factors to predict blood glucose levels independently of other parameters, hence reducing the burden on the patients. …”
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PPARβ/δ Agonism with GW501516 Increases Myotube PGC-1α Content and Reduces BCAA Media Content Independent of Changes in BCAA Catabolic Enzyme Expression by Caroline N. Rivera, Jason S. Hinkle, Rachel M. Watne, Trent C. Macgowan, Andrew J. Wommack, Roger A. Vaughan

“…Type 2 diabetes is characterized by reduced insulin sensitivity, elevated blood metabolites, and reduced mitochondrial metabolism with reduced expression of genes governing metabolism such as peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α). …”
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Autoantibodies to Zinc Transporter 8 and SLC30A8 Genotype in Type 1 Diabetes Childhood: A Pioneering Study in North Africa by Raouia Fakhfakh, Sana Kmiha, Safa Tahri, Sawsan Feki, Ferjeni Zouidi, Olfa Abida, Mongia Hachicha, Thouraya Kammoun, Hatem Masmoudi

“…Type 1 diabetes (T1D) occurs as a result of insulin deficiency due to destructive lesions of pancreatic β cells. …”
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Taenia crassiceps Antigens Control Experimental Type 1 Diabetes by Inducing Alternatively Activated Macrophages by Arlett Espinoza-Jiménez, Roberto De Haro, Luis I. Terrazas

“…Type 1 diabetes (T1D) is an autoimmune disease caused by the selective destruction of the pancreatic β-cells, causing inability to produce insulin. Proinflammatory cytokines such as IL-1β, IL-6, TNF-α, IFN-γ, IL-12, IL-17, and NO can be released by CD4 and CD8+ lymphocytes as well as by classically activated macrophages (CAMϕs), which are important in the development of T1D. …”
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Differential expression of plasma proteins and pathway enrichments in pediatric diabetic ketoacidosis by Paolo Spagnolo, Enis Cela, Maitray A. Patel, David Tweddell, Mark Daley, Cheril Clarson, Saverio Stranges, Gediminas Cepinskas, Douglas D. Fraser

“…Methods We conducted a proteome analysis of plasma samples from 17 matched pairs of pediatric patients with T1D; one cohort with severe DKA and another with insulin-controlled diabetes. Proximity extension assays were used to quantify 3072 plasma proteins. …”
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BMI trajectories are associated with NAFLD and advanced fibrosis via aging-inflammation mediation by Haiyang Peng, Zhibo Zhao, Jianping Gong, Kun He

“…This mediation on NAFLD was independent of insulin resistance (IR). The association between rapid ascending trajectory and advanced fibrosis was more pronounced among the male subgroup (p for interaction = 0.008). …”
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Blockade of Vascular Endothelial Growth Factor Receptor 1 Prevents Inflammation and Vascular Leakage in Diabetic Retinopathy by Jianbo He, Hong Wang, Ying Liu, Wen Li, Dorothy Kim, Hu Huang

“…Experimental models of diabetes were induced with streptozotocin (STZ) treatment or Insulin2 gene mutation (Akita) in mice. Protein expression and localization were examined by western blots (WB) and immunofluorescence (IF). mRNA expression was quantified by PCR array and real-time PCR. …”
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Acute Pancreatitis Induced by Diabetic Ketoacidosis with Major Hypertriglyceridemia: Report of Four Cases by Karama Bouchaala, Mabrouk Bahloul, Sabrine Bradii, Hela Kallel, Kamilia Chtara, Mounir Bouaziz

“…Our patients were admitted into our ICU where they received fluid resuscitation and intravenous insulin, and their triglycerides rates decreased gradually. …”
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Conditioned Medium from Adipose-Derived Stem Cell Inhibits Jurkat Cell Proliferation through TGF-β1 and p38/MAPK Pathway by Xiuxia Wang, Yinmin Wang, Xianyu Zhou, Fei Liu

“…The transcript abundance of TGF-β1, as well as that of insulin-like growth factor binding protein 3 (IGF-BP3), was evaluated using qRT-PCR on Jurkat cells cultured in ADSC-CM for 24 hours. …”
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Waist-to-Height Ratio Is a Better Anthropometric Index than Waist Circumference and BMI in Predicting Metabolic Syndrome among Obese Mexican Adolescents by Edel Rafael Rodea-Montero, María Lola Evia-Viscarra, Evelia Apolinar-Jiménez

“…WHtR ≥0.62 and WHtR ≥0.61 generate AUC of 0.737 (P=0.006) and AUC of 0.717 (P=0.014) for predicting hypertension and insulin resistance, respectively, in females. Conclusion. …”
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Detection of Amylin-β-amyloid Hetero-Oligomers by Enzyme-Linked Immunosorbent Assay by Noah Leibold, Deepak Kotiya, Nirmal Verma, Florin Despa

“…Amylin is an amyloidogenic neuroendocrine hormone co-synthesized and co-secreted with insulin from the pancreas. It readily crosses the blood–brain barrier and synergistically forms mixed amyloid plaques with β-amyloid (Aβ) in brain parenchyma. …”
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A Prediction Model for Prediabetes Risk in Middle-Aged and Elderly Populations: A Prospective Cohort Study in China by Jiahua Wu, Jiaqiang Zhou, Xueyao Yin, Yixin Chen, Xihua Lin, Zhiye Xu, Hong Li

“…In the univariate analyses, fasting plasma glucose (FPG), fasting serum insulin (FINS), 2 h plasma glucose (2hPG), HbA1c, serum uric acid (SUA), waist circumference (WC), smoking, and family history of diabetes (FHD) were found to be significantly correlated with prediabetes. …”
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Diabetic Polyneuropathy in Type 2 Diabetes Mellitus: Inflammation, Oxidative Stress, and Mitochondrial Function by Luis Miguel Román-Pintos, Geannyne Villegas-Rivera, Adolfo Daniel Rodríguez-Carrizalez, Alejandra Guillermina Miranda-Díaz, Ernesto Germán Cardona-Muñoz

“…Risk factors include age, male gender, duration of diabetes, uncontrolled glycaemia, height, overweight and obesity, and insulin treatment. Several diagnostic methods have been developed, and composite scores combined with nerve conduction studies are the most reliable to identify early DPN. …”
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The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity by Lynda Bourebaba, Anna Serwotka-Suszczak, Nabila Bourebaba, Magdalena Zyzak, Krzysztof Marycz

“…Hyperactivation of protein tyrosine phosphatase (PTP1B) has been associated with several metabolic malfunctions ranging from insulin resistance, metaflammation, lipotoxicity, and hyperglycaemia. …”
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Ranolazine Induced Bradycardia, Renal Failure, and Hyperkalemia: A BRASH Syndrome Variant by Syed Arsalan Akhter Zaidi, Danial Shaikh, Muhammad Saad, Timothy J. Vittorio

“…Laboratory studies were significant for a serum potassium level of 6.8 mEq/L and a serum creatinine level of 1.6 mg/dL. She was given insulin with dextrose, sodium polystyrene, and calcium gluconate in addition to fluids. …”
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Menopausal Hormone Therapy: Its Role in the Prevention of Cardiovascular Diseases and the Risk of Breast Cancer in Women by Tam Thai Thanh Tran, Thu Minh Phung, Anh Thi Mai Do, Quynh Tran Mai Ly, Tin Hoang Nguyen

“…Mechanism: Estrogen deficiency, altered energy homeostasis, adipocyte changes, inflammation, and insulin resistance are responsible for the development of metabolic syndrome and CVDs. …”
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Extent, causes, and consequences of small RNA expression variation in human adipose tissue. by Leopold Parts, Åsa K Hedman, Sarah Keildson, Andrew J Knights, Cei Abreu-Goodger, Martijn van de Bunt, José Afonso Guerra-Assunção, Nenad Bartonicek, Stijn van Dongen, Reedik Mägi, James Nisbet, Amy Barrett, Mattias Rantalainen, Alexandra C Nica, Michael A Quail, Kerrin S Small, Daniel Glass, Anton J Enright, John Winn, MuTHER Consortium, Panos Deloukas, Emmanouil T Dermitzakis, Mark I McCarthy, Timothy D Spector, Richard Durbin, Cecilia M Lindgren

“…Trunk fat mass, body mass index, and fasting insulin were associated with more than twenty small RNA expression levels each, while fasting glucose had no significant associations. …”
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Long-Term GAD-alum Treatment Effect on Different T-Cell Subpopulations in Healthy Children Positive for Multiple Beta Cell Autoantibodies by Falastin Salami, Lampros Spiliopoulos, Marlena Maziarz, Markus Lundgren, Charlotte Brundin, Rasmus Bennet, Magnus Hillman, Carina Törn, Helena Elding Larsson

“…The Diabetes Prevention–Immune Tolerance 2 (DiAPREV-IT 2) clinical trial enrolled 26 children between 4 and 13 years of age, positive for glutamic acid decarboxylase autoantibody (GADA) and at least one other autoantibody (insulin, insulinoma antigen-2, or zinc transporter 8 autoantibody (IAA, IA-2A, or ZnT8A)) at baseline. …”
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The type of diet consumed during prepuberty modulates plasma cholesterol, hepatic LXRα expression, and DNA methylation and hydroxymethylation during adulthood in male rats. by Ana Aguilar-Lozano, Berenice Palacios-González, Martha Guevara-Cruz, Armando R Tovar, Alam Palma-Guzman, Lilia G Noriega

“…The prepubertal CD prevented fat mass accumulation, lean mass loss and metabolic inflexibility, showed lower insulin, leptin and cholesterol concentrations in adulthood despite the chronic HFD. …”
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