Pathophysiology of Resistant Hypertension: The Role of Sympathetic Nervous System by Costas Tsioufis, Athanasios Kordalis, Dimitris Flessas, Ioannis Anastasopoulos, Dimitris Tsiachris, Vasilios Papademetriou, Christodoulos Stefanadis

“…Current clinical and experimental knowledge points towards an impact of several factors on SNS activation, namely, insulin resistance, adipokines, endothelial dysfunction, cyclic intermittent hypoxaemia, aldosterone effects on central nervous system, chemoreceptors, and baroreceptors dysregulation. …”
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The Association of COPD Exacerbations with New Onset Type 2 Diabetes among Medicare Patients by Joseph S. Marino, Cynthiya Ruban, Christopher M. Blanchette

“…Exacerbations of COPD are commonly treated with corticosteroids, a class of drug known to cause insulin resistance. The objective of this study was to assess the rate of exacerbations requiring emergency room visits, hospitalizations or any medical encounter (a combination of emergency room and hospitalizations) between COPD patients who did and did not develop type 2 diabetes. …”
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Case report: Looking for relationship between type 1 diabetes and chronic recurrent osteomyelitis: short literature review and case presentation by Ausra Snipaitiene, Laura Radzeviciute, Kristina Aleknaviciene, Rimante Dobrovolskiene, Ingrida Stankute

“…However, a stable clinical status was ultimately achieved upon the introduction of methotrexate, concomitant with insulin therapy for diabetes and the implementation of a gluten-free diet for celiac disease.ConclusionsOur case showed that the combination of autoimmune and autoinflammatory diseases, brought not only a challenging diagnostic process, but also complicated treatment.…”
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A High-Fat, High-Fructose Diet Induces Antioxidant Imbalance and Increases the Risk and Progression of Nonalcoholic Fatty Liver Disease in Mice by Kanokwan Jarukamjorn, Nattharat Jearapong, Charinya Pimson, Waranya Chatuphonprasert

“…Excessive fat liver is an important manifestation of nonalcoholic fatty liver disease (NAFLD), associated with obesity, insulin resistance, and oxidative stress. In the present study, the effects of a high-fat, high-fructose diet (HFFD) on mRNA levels and activities of the antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx), were determined in mouse livers and brains. …”
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Phytochemical constituent, α-amylase and α-glucosidase inhibitory activities of Black Soybean (Glycine soja (L.) Merr.) ethanol extract by Afifah Bambang Sutjiatmo, Suci Narvikasari, Ananda Khairunisa Solihat, Wahyu Widowati, Hanna Sari Widya Kusuma, Fadhilah Haifa Zahiroh

“… Diabetes is characterized as a hyperglycemic condition impacted by β-cell dysfunction and insulin deficiency. Black soybean (Glycine soja (L.) …”
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Destabilization signs in behavioral and somatovegetative parameters of rats selected for catatonia by T. A. Alekhina, N. A. Palchikova, R. V. Kozhemyakina, O. I. Prokudina

“…However, the strains did not differ in the concentration of insulin, which affects glucose transport through the cell membrane. …”
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Results of the Implementation of a Tool for the Stratification and Management of Diabetic Patients with Uncomplicated Acute Hyperglycemia in the Emergency Department by Luis Alberto Corona Martínez, Laydamí Rodríguez Amador

“…Adherence to the suggested initial procedures was low (57%), which was determined by the outcomes in the group two (13%) since most of the patients were not admitted to the observation ward. Adherence to insulin therapy was higher (67%). Adherence to the recommended follow-up was low due to early discharge of patients. …”
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A De Novo Whole GCK Gene Deletion Not Detected by Gene Sequencing, in a Boy with Phenotypic GCK Insufficiency by N. H. Birkebæk, J. S. Sørensen, J. Vikre-Jørgensen, P. K. A. Jensen, O. Pedersen, T. Hansen

“…After three years on neutral insulin Hagedorn (NPH) in a dose of 0.3 IU/kg/day haemoglobin A1c (HbA1c) was 6.8%. …”
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Tip 2 Diyabetes Mellituslu Hastaların Hastalıklarına Yönelik Tutum ve Davranışlarının İncelenmesi by Ahmet Kayabaşı, Yasemin Korkut

“…Klinik özelliklerin dağılımına göre,% 50.3'ü 10 yıl boyunca diyabet geçirirken,% 25.7'si tedavide insülin kullanıyordu,% 14.8'i diyabetik ayağı vardı. …”
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Effect of a high-fat diet and iron overload on erythropoiesis in mice by Joe Varghese, Jithu James Varghese, Molly Jacob

“…Background: Insulin and iron availability stimulate and regulate erythropoiesis, respectively. …”
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Alcohol Consumption and Risk of All-Cause and Cardiovascular Disease Mortality in Men by Erin K. Howie, Xuemei Sui, Duck-chul Lee, Steven P. Hooker, James R. Hébert, Steven N. Blair

“…The addition of other potential confounders and effect modifiers including blood pressure, insulin sensitivity, lipid levels, and psychological variables did not affect the magnitude of association. …”
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PPARγ and Its Agonists in Chronic Kidney Disease by Yuhua Ma, Manman Shi, Yuxin Wang, Jian Liu

“…Its agonists such as thiazolidinediones (TZDs) have been applied as effective antidiabetic drugs as they control insulin sensitivity in multiple metabolic tissues. …”
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Principles of management of patient with asymptomatic elevation of serum aminotransferases by Ye. N. German, M. V. Mayevskaya, Ye. O. Lyusina, V. T. Ivashkin

“…For treatment of nonalcoholic steatohepatitis it is rational to use as drugs of choice metformin (treatment of insulin resistance) and ursodeoxycholic acid (anti-oxidative properties).…”
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High-fat diet and neuroinflammation: The role of mitochondria by Mingxue Song, Yao Bai, Fuyong Song

“…More importantly, mitochondrial damage, neuroinflammation, and insulin resistance caused by HFD form a mutually reinforcing vicious cycle, ultimately leading to the death of neurons and promoting the progression of neurodegenerative diseases. …”
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Antihyperglycemic Activity of Houttuynia cordata Thunb. in Streptozotocin-Induced Diabetic Rats by Manish Kumar, Satyendra K. Prasad, Sairam Krishnamurthy, Siva Hemalatha

“…Oral administration of extract at 200 and 400 mg/kg dose level daily for 21 days showed a significant (P<0.05) decrease in fasting plasma glucose and also elevated insulin level in streptozotocin-induced diabetic rats. …”
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Visfatin/Nampt: An Adipokine with Cardiovascular Impact by Tania Romacho, Carlos F. Sánchez-Ferrer, Concepción Peiró

“…Visfatin was initially identified as a novel adipokine with insulin-mimetic properties in mice. This adipokine was identical to two previously described molecules, namely, pre-B cell colony-enhancing factor (PBEF) and the enzyme nicotinamide phosphoribosyltransferase (Nampt). …”
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Pituitary Macroadenoma and Severe Hypothyroidism: The Link between Brain Imaging and Thyroid Function by Silvia Ciancia, Silvia Cesari, Barbara Predieri, Sergio Bernasconi, Lorenzo Iughetti

“…We report the case of a 12-year-old boy who was evaluated for impaired growth velocity and increased body weight. Because of low insulin-like growth factor 1 levels and poor response to the growth hormone stimulation test, brain magnetic resonance imaging was performed and a pituitary macroadenoma was found. …”
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Anabolic androgenic steroids intake and its impact on male reproductive system - systematic review by Maja Mielczarek, Paulina Sroczyńska, Jan Sroczyński, Julia Lachowska, Karolina Senior, Jerzy Smandek

“…AAS bind to androgen receptors, promoting muscle growth by increasing protein synthesis and promoting the growth hormone-insulin-like growth factor 1 axis. AAS are commonly administered via intramuscular injection or oral ingestion. …”
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Differential Effects of Calorie Restriction and Exercise on the Adipose Transcriptome in Diet-Induced Obese Mice by Karrie E. Wheatley, Leticia M. Nogueira, Susan N. Perkins, Stephen D. Hursting

“…Relative to the DIO controls, both CR and EX reduced adiposity by 35–40% and serum leptin levels by 80%, but only CR increased adiponectin and insulin sensitivity. Gene expression microarray analysis of visceral white adipose tissue revealed 209 genes responsive to both CR and EX, relative to the DIO group. …”
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Nocturnal Light Pollution Synergistically Impairs Glucose Metabolism With Age and Weight in Monkeys by Shuxing Wang, Xuange Cheng, Zihao Liang, Zhenyi Chen, Jiankai Zhang, Qiang Xu

“…Data pertaining to the mortality rate of preexisting diabetes, incidence of light-induced diabetes and IGT, and alterations in insulin secretion were collected and analyzed. The results show that nocturnal light (1) caused premature deaths in individuals with preexisting diabetes; (2) intensity-dependently induced diabetes and IGT in previous healthy monkeys; (3) intensity-dependently reduced melatonin secretion; (4) had a synergistic impairing effect on glucose metabolism with aging and weight; and (5) although monkeys would eventually adapt to the environment, the disrupted glucose metabolism would not fully recover in most individuals. …”
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