Verification of Lactobacillus brevis tolerance to simulated gastric juice and the potential effects of postbiotic gamma-aminobutyric acid in streptozotocin-induced diabetic mice by Amro Abdelazez, Heba Abdelmotaal, Smith Etareri Evivie, Maha Bikheet, Rokayya Sami, Hassan Mohamed, Xiangchen Meng

“…One group was injected with insulin (INSSTZ). The body weight and hyperglycemia in the blood were assessed weekly, post-euthanasia blood plasma parameters, insulin, and histological examination were evaluated. …”
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Skipping Breakfast Is Associated with an Atherogenic Lipid Profile in Overweight and Obese Prepubertal Children by A. Blasetti, S. Franchini, V. Castorani, L. Comegna, E. Fornari, F. Daniele, G. Prezioso, C. Piona, V. Federico, D. Zona, I. Bresadola, F. Chiarelli, C. Maffeis

“…Hormones, in particular, insulin-like growth factor-1 (IGF-1), may potentially play a role in the metabolic profile of breakfast skippers. …”
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Effect of antioxidant capsule supplementation on oxidative stress markers in hypertensive patients by Novaes-Gaeta Ludmila N., Moraes Mariele C., Katayama Keyla Y., Sangaletti Carine T., Irigoyen Maria Claudia, Freitas Sarah, Viana Ariane, de Angelis Katia, Caldini Elia G., Lopes Heno F.

“…A significant intragroup difference in homeostatic model assessment of insulin resistance (HOMAir) was noted between normotensive and hypertensive individuals at different times. …”
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High-fat diet promotes gestational diabetes mellitus through modulating gut microbiota and bile acid metabolism by Lei Yao, Xuefei Zhou, Xianqi Jiang, Hao Chen, Yuanliang Li, Xiao Xiong, Yan Tang, Haogang Zhang, Pengfei Qiao

“…Body weight, average feed intake, blood glucose, insulin levels and oral glucose tolerance test was performed among each groups. …”
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Efek Latihan Fisik Terhadap Remodeling Jantung by Rita Hamdani, Finesa A Hasye

“…Latihan fisik teratur menurunkan risiko PKV dengan cara: mengurangi trigliserida, meningkatkan kolesterol HDL, menurunkan tekanan darah, meningkatkan metabolisme glukosa serta sensitivitas insulin, mengurangi berat badan dan mengurangi respon inflamasi. …”
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Comparative Effects of Sulforaphane and Allyl Isothiocyanate on 3T3-L1 Adipogenesis by Satoru Sakuma, Kana Yasuda, Risa Kitahara, Kaho Tsujimoto, Kishiko Yamashita, Naohiro Hoshino, Yohko Fujimoto, Keiichiro Okuhira

“…In the present study, we compared the effects of sulforaphane and allyl isothiocyanate on the differentiation of 3T3-L1 preadipocytes. A mixture of insulin, dexamethasone, and 3-isobutyl-1-methylxanthine was used to establish a differentiation medium. …”
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Epigenetic Modifications and Potential New Treatment Targets in Diabetic Retinopathy by Lorena Perrone, Carmela Matrone, Lalit P. Singh

“…Evidences have provided that after a period of poor glucose control insulin or diabetes drug treatment fails to prevent the development and progression of DR even when good glycemic control is reinstituted (glucose normalization), suggesting a metabolic memory phenomenon. …”
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Nonislet Cell Tumor Hypoglycemia in a Patient with Adrenal Cortical Carcinoma by Se Won Kim, Seung-Eun Lee, Young Lyun Oh, Seokhwi Kim, Sun Hee Park, Jae Hyeon Kim

“…Nonislet cell tumor hypoglycemia (NICTH) is a rare but serious paraneoplastic syndrome in which a tumor secretes incompletely processed precursors of insulin-like growth factor-II (IGF-II), causing hypoglycemia. …”
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Guiding the Differentiation Direction of Pancreatic Islet-Derived Stem Cells by Glycated Collagen by Gokhan Duruksu, Aysegul Aciksari

“…It was found that the mannose-modified collagen stimulated the adipogenic differentiation of stem cells, and rhamnose-modified collagen supports the differentiation into both osteogenic and insulin-producing cells. The low concentration of monosaccharides during glycation process improved the characteristics of the matrix protein in favor of stem cell differentiation. …”
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Management of a Dog with Poorly Regulated Diabetes Mellitus, Chronic Pancreatitis, and Suspected Atopy with Cyclosporine by Jörg M. Steiner, Brian J. Huber

“…Multiple adjustments of insulin therapy did not improve control of diabetes mellitus. …”
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DEZVOLTAREA UNEI ARHITECTURI DE MODEL BAZAT PE REȚELE NEURONALE PENTRU CALCULUL PERSONALIZAT AL DOZELOR DE INSULINĂ ÎN DIABETUL ZAHARAT DE TIP I by USM ADMIN

“… Diabetul zaharat de tip I este o boală cronică autoimună, caracterizată prin deficienţa hormonului insulin in organism, astfel că pacienții au nevoie de administrare externă a acestui hormon pentru a supraviețui. …”
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Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention by Andrew T. Ludlow, Stephen M. Roth

“…Several reports have recently associated telomeres and telomere-related proteins to diseases associated with physical inactivity and aging including cardiovascular disease, insulin resistance, and hypertension. Interestingly several reports have also shown that longer telomeres are associated with higher physical activity levels, indicating a potential mechanistic link between physical activity, reduced age-related disease risk, and longevity. …”
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Reverse epidemiology of obesity paradox: Fact or fiction? by Bellamkonda K. Kishore

“…Evidence suggests that the development of obesity and insulin resistance are influenced by genetic (or ethnic) make up and dietary habits (culture) of the individuals. …”
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Dietary Conjugated Linoleic Acid and Hepatic Steatosis: Species-Specific Effects on Liver and Adipose Lipid Metabolism and Gene Expression by Diwakar Vyas, Anil Kumar G. Kadegowda, Richard A. Erdman

“…The potential role of liver FA composition, insulin secretion and sensitivity, adipokine, and inflammatory responses are discussed as potential mechanisms behind CLA-induced hepatic steatosis.…”
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Adropin as an indicator of T2DM and its complications by Hu Zhang, Ning Chen

“…As a secreted peptide, adropin is identified as a useful regulator associated with insulin sensitivity and energy homeostasis. It has the potential for regulating metabolic diseases including obesity and T2DM. …”
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FGF21 as an Endocrine Regulator in Lipid Metabolism: From Molecular Evolution to Physiology and Pathophysiology by Yusuke Murata, Morichika Konishi, Nobuyuki Itoh

“…Serum FGF21 levels are increased in patients with metabolic diseases having insulin resistance, indicating that FGF21 is a metabolic regulator and a biomarker for these diseases.…”
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Nonalcoholic Fatty Liver Disease and Sarcopenia: Where Do We Stand? by Ivana Mikolasevic, Tajana Pavic, Tajana Filipec Kanizaj, Darija Vranesic Bender, Viktor Domislovic, Zeljko Krznaric

“…Crucial mechanisms involved in sarcopenia-nonalcoholic fatty liver disease (NAFLD) interplay are based on effects of insulin resistance, chronic inflammation, oxidative stress, and crosstalk between organs by secretion of cytokines (hepatokines, adipokines, and myokines). …”
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Triglyceride-Glucose Index and its Relationship to Erectile Dysfunction in Subjects without Heart Disease by Sudeep Jayaram, S Santhosh, Nikhil Vaidya, Arifa Bakerywala, Harsh Anadkat, Heena Shaikh

“…Conclusion: I n patients with erectile dysfunction, the TyG index—a simple test for insulin resistance (IR) —was found to be predictive.…”
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Bariatric Surgery, Polycystic Ovary Syndrome, and Infertility by James Butterworth, Jean Deguara, Cynthia-Michelle Borg

“…Visceral obesity and insulin resistance are key pathophysiological mechanisms behind PCOS. …”
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Endocrine Actions of Osteocalcin by Aurora Patti, Luigi Gennari, Daniela Merlotti, Francesco Dotta, Ranuccio Nuti

“…Recent provocative data from experimental observations in mice showed that the circulating undercarboxylated fraction of osteocalcin increases insulin secretion and sensitivity, lowers blood glucose, and decreases visceral fat in both genders, while it enhances testosterone production by the testes in males. …”
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