A Rare Case of Persistent Lactic Acidosis in the ICU: Glycogenic Hepatopathy and Mauriac Syndrome by Kirsten S. Deemer, George F. Alvarez

“…This case demonstrates exacerbation of lactic acidosis in a patient with glycogenic hepatopathy treated for diabetic ketoacidosis with high dose insulin and dextrose.…”
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Nonalcoholic Fatty Liver Disease: A Clinical Approach and Review by Maitreyi Raman, Johane Allard

“…The primary abnormality or ‘first hit’ in patients with NAFLD is insulin resistance leading to hepatic steatosis. The second hit involves multiple proinflammatory cytokines resulting in non-alcoholic steatohepatitis. …”
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Pentraxin 3 Levels in Young Women with and without Polycystic Ovary Syndrome (PCOS) in relation to the Nutritional Status and Systemic Inflammation by Katarzyna Wyskida, Grzegorz Franik, Piotr Choręza, Natalia Pohl, Leszek Markuszewski, Aleksander Owczarek, Paweł Madej, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…Homeostatic model assessment of insulin resistance (HOMA-IR) was made. Results. Plasma PTX3, TNF-α, and IL-6 levels and HOMA-IR were higher in PCOS than in non-PCOS group p<0.001. …”
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Naringin prevents heart mitochondria dysfunction during diabetic cardiomyopathy in rats by Ilya Zavodnik, Tatsiana A. Kavalenia, Siarhei N. Kirko, Elena B. Belonovskaya, Irina A. Kuzmitskaya, Yulia V. Eroshenko, Elena A. Lapshina, Vyacheslav U. Buko

“…Experimental approach: Type 1 diabetes was induced by an intraperitoneal injection of streptozotocin (40 mg/kg) in rats and islet morphology, glucose and insulin levels, changes in heart mitochondria respiration, membrane potential, spontaneous and Ca2+ - induced mitochondrial permeability transition (MPT) pore opening were evaluated. …”
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Assessment of the hypoglycemic effect of Cyanthillium cinereum (L.) H. Rob. and its dual impact on uterine contraction in gestational diabetic rats by Sasitorn Kerdsuknirund, Arreeya Kosinan, Panida Khunkaewla, Pakanit Kupittayanant, Pattama Tongdee, Porntip Nimkuntod, Susan Wray, Sajeera Kupittayanant

“…Both treatments showed a trend toward increased insulin levels (P > 0.05) and significantly reduced lipids, AST, and ALP levels (P < 0.05). …”
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Fasting-Evoked En Route Hypoglycemia in Diabetes (FEEHD): An Overlooked Form of Hypoglycemia in Clinical Practice by Saleh Aldasouqi, Samia Mora, Gaurav Bhalla, Naveen Kakumanu, William Corser, George Abela, Mohammad Dlewati, Kathleen Estrada, Abdul Almounajed, Tarek Tabbaa, Jamal Hammoud, Cathy Newkirk

“…Of the 269 patients who were at higher risk of FEEHD (on insulin secretagogues or on insulin), 59 (21.9%) reported having experienced FEEHD. …”
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The Effect of Low Carbohydrate Diet on Polycystic Ovary Syndrome: A Meta-Analysis of Randomized Controlled Trials by Xiaoshuai Zhang, Yang Zheng, Yanan Guo, Zhiwen Lai

“…Based on the current evidence, LCD, particularly long-term LCD and low-fat/low-CHO LCD, may be recommended for the reduction of BMI, treatment of PCOS with insulin resistance, prevention of high LDL-C, increasing the levels of FSH and SHBG, and decreasing the level of T level. …”
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Combined Administration of Streptozotocin and Sucrose Accelerates the Appearance of Type 2 Diabetes Symptoms in Rats by Martha Isela Barragán-Bonilla, Juan Miguel Mendoza-Bello, Penélope Aguilera, Isela Parra-Rojas, Berenice Illades-Aguiar, Mónica Ramírez, Mónica Espinoza-Rojo

“…Type 2 diabetes is a disease with a high global prevalence, characterized by chronic hyperglycemia, insulin resistance, polyphagia, polydipsia, polyuria, and changes in body weight. …”
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Preterm Birth and Cardiometabolic Health Trajectories From Birth to Adulthood: The Avon Longitudinal Study of Parents and Children by Gemma L. Clayton, Laura D. Howe, Linda M. O'Keeffe, Adam J. Lewandowski, Deborah A. Lawlor, Abigail Fraser

“…There was no evidence of differences in glucose and insulin. Conclusions Few, modest differences in cardiometabolic health were found in those born preterm versus term. …”
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Ficus deltoidea standardized methanolic extract improves kidney structure and function against streptozotocin-induced diabetic nephropathy in rats by Nurdiana Samsulrizal, Noor Syaffinaz Noor Mohamad Zin, Nur Syimal`ain Azmi, Mohd Daud Bakar, Hafandi Ahmad, Yong-Meng Goh

“…Background: Oxidative stress and peripheral insulin resistance are the key pathogenesis of diabetic nephropathy. …”
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Association between dietary betaine intake and overweight or obesity by Maierheba Kuerbanjiang, Wenzhuo Yu, Ting Shang, Yuchen Liu, Dina Muheyati, Mei-Xia Lv, Muhairemu Jielili, Jia Han

“…A total of 492 subjects from a dietary survey were equally classified into four groups (Q1, Q2, Q3, and Q4) according to the quartiles of dietary betaine intake and further investigate the correlation of betaine intake with body weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), waist-to-hip ratio (WHR), triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), fasting blood glucose (FBG), fasting insulin (FINS), homeostasis model assessment of insulin resistance (Homa-IR), systolic blood pressure (SBP), and diastolic blood pressure (DBP). …”
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Optimization of the extraction methods and evaluation of the hypoglycemic effect of Adhatoda Zeylanica extracts on artificially induced diabetic mice by Md Fahim Ahmed, Khalid Hasan Raby, Nishat Tasnim, Md Tariful Islam, Mahbub Chowdhury, Zarin Tasnim Juthi, Md Ashik Mia, Lubna Jahan, A.K.M. Zakir Hossain, Shoeb Ahmed

“…These plant extracts regulate diabetes by restoring pancreatic function, enhancing insulin secretion, inhibiting intestinal glucose absorption, and facilitating insulin dependent metabolism. …”
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Assessment of diabetes-specific eating disorder risk in adult patients with diabetes by Afruz Babayeva, Shovket Alishova, Gunay Mammadova, Meric Coskun, Ethem Turgay Cerit, Alev Eroglu Altinova, Mujde Akturk, Fusun Balos Toruner, Mehmet Ayhan Karakoc, Mehmet Muhittin Yalcin

“…Our study aimed to investigate the prevalence of DEB in patients with T1D and T2D on intensive insulin therapy followed in our outpatient clinic. …”
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Investigating misclassification of type 1 diabetes in a population-based cohort of British Pakistanis and Bangladeshis using polygenic risk scores by Timing Liu, Alagu Sankareswaran, Gordon Paterson, Genes & Health Research Team, Diane P. Fraser, Sam Hodgson, Qin Qin Huang, Teng Hiang Heng, Meera Ladwa, Nick Thomas, David A. van Heel, Michael N. Weedon, Chittaranjan S. Yajnik, Richard A. Oram, Giriraj R. Chandak, Hilary C. Martin, Sarah Finer

“…Using linked health records from the Genes & Health cohort (n = 38,344) we defined two reference groups meeting stringent diagnostic criteria: 31 T1D cases, 1842 T2D cases, and after excluding these, two further groups: 839 insulin-treated diabetic individuals with ambiguous features and 5174 non-diabetic controls. …”
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4-Phenylbutyric Acid Attenuates Pancreatic Beta-Cell Injury in Rats with Experimental Severe Acute Pancreatitis by Yu-pu Hong, Wen-yi Guo, Wei-xing Wang, Liang Zhao, Ming-wei Xiang, Fang-chao Mei, Ablikim Abliz, Peng Hu, Wen-hong Deng, Jia Yu

“…Results showed that 4-PBA attenuated the following: (1) pancreas and islet pathological injuries, (2) serum TNF-α and IL-1β, (3) serum insulin and glucose, (4) beta-cell ultrastructural changes, (5) ER stress markers (BiP, ORP150, and CHOP), Caspase-3, and insulin expression in islet. …”
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The association between TyG index and cardiovascular mortality is modified by antidiabetic or lipid-lowering agent: a prospective cohort study by Changchang Fang, Nanqin Peng, Jiang Cheng, Xiyu Zhang, Wenli Gu, Zicheng Zhu, Xiaoping Yin, Zhiwei Yan, Jing Zhang, Peng Yu, Xiao Liu

“…Abstract Background The triglyceride-glucose (TyG) index is recognized as an alternative measure of insulin resistance (IR) and has been linked to the risks of cardiovascular disease (CVD) and mortality. …”
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Changes in Techno-Functional Characteristics of Cow Colostrum Powder Prepared by Freeze Drying by Anamika Das, Raman Seth, Ayon Tarafdar, Swarnima Dey, Yogesh Kumar, Ranjna Sirohi

“…In freeze-dried bovine skimmed colostrum powder (BSCP) and bovine colostrum whey powder (BCWP), IgG emerged as the highest fraction among immune factors, whereas in growth factors, insulin-like growth factor 1(IGF1) and transforming growth factor β2 (TGFβ2) were found in large proportion as compared to insulin-like growth factor 2 (IGF2) and transforming growth factor β1 (TGFβ1). …”
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Association between domain-specific physical activity and triglyceride‑glucose (TyG) index among US adults: Evidence from NHANES 2007–2018 by Kai Yao

“…Abstract Objectives The triglyceride-glucose (TyG) index is not only a reliable marker for insulin resistance, but also has broad applications in assessing the risk of various diseases, including cardiovascular disease, stroke, depression, and Alzheimer’s disease. …”
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Circulating Monocyte and Lymphocyte Populations in Healthy First-Degree Relatives of Type 2 Diabetic Patients at Fasting and during Short-Term Hyperinsulinemia by Michaela Šiklová, Eva Krauzová, Barbora Svobodová, Jana Kračmerová, Marek Štěpán, Michal Koc, Vladimír Štich, Lenka Rossmeislová

“…The CD4/CD8 ratio correlated with fat mass, insulin, and HOMA-IR in the entire group of subjects. …”
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Serological markers of exocrine pancreatic function are differentially informative for distinguishing individuals progressing to type 1 diabetes by Desmond Schatz, Laura Jacobsen, Todd M Brusko, Michael J Haller, Mark Atkinson, MacKenzie D Williams, Catherine Ramsey Grace, Amanda L Posgai, Kieran M McGrail, Maigan A Brusko, Rhonda Bacher, Clive H Wasserfall

“…AAb against ZnT8 (p&lt;0.01), GAD65 (p=0.021), or insulin (p=0.01) each independently favored ≥2AAb+ versus 1AAb+ classification. …”
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