Implications of prognostic nutritional index in predicting adverse outcomes of uncontrolled diabetic patients: a cohort study of the national health and nutrition examination surve... by Fei Liu, Zhili Jiang, Wei Luo, Yunxiao Yang, Shuai Guo, Jiayi Yi, Geng Shen, Wei Li, Lin Wang, Xiuhuan Chen, Zhaogong Zhi, Tian Liu, Xuedong Zhao, Chen Li, Hai Gao

“…Improvement of PNI could enhance the effective of antidiabetic therapy, especially the insulin therapy, and reduce DM-related mortality.…”
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Glucose level regulation via integral high-order sliding modes by Lela Dorel

“…Diabetes is a condition in which the body eitherdoes not produce enough insulin, or does not properly respond to it.This causes the glucose level in blood to increase. …”
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C-Peptide: A New Mediator of Atherosclerosis in Diabetes by Dusica Vasic, Daniel Walcher

“…Diabetes type 2 and insulin resistance are the risk factors for cardiovascular disease. …”
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Healthy Living: Diabetes by Linda B. Bobroff, Karla P Shelnutt, Paulina Wittkowsky

“… Diabetes is a serious health condition that occurs when a person’s body has difficulty making or using insulin, which results in high blood glucose (blood sugar) and can lead to other complications. …”
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Synaptosomal Protein of 25 kDa (Snap25) Polymorphisms Associated with Glycemic Parameters in Type 2 Diabetes Patients by Nasser M. Al-Daghri, Andrea S. Costa, Majed S. Alokail, Milena Zanzottera, Amal M. Alenad, Abdul Khader Mohammed, Mario Clerici, Franca R. Guerini

“…In these same patients, insulin levels were significantly decreased compared to the (AA) individuals (f=7.29, df=1, and p=0.009). …”
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Hypercysteinemia, A Potential Risk Factor for Central Obesity and Related Disorders in Azores, Portugal by Ana Lima, Rita Ferin, Mafalda Bourbon, José Baptista, M. Leonor Pavão

“…Moreover, plasma Cys levels predicted waist circumference (β coefficient = 0.102, P=0.032) and concomitant central obesity and were also associated with insulin resistance. Nevertheless, hyperhomocysteinemia prevalence was similar in both groups, despite the fact that PDL subjects exhibited a higher rate of vitamin B12 deficiency compared to those from Lisbon (19% vs. 6%, P=0.003). …”
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Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition by Yongkang Liu, Fan Yang, Sijing Wan, Xianzhong Wang, Liwen Guan, Yan Li, Caidi Xu, Binghua Xie, Shigui Wang, Xiao-Ling Tan, Bin Tang

“…The overlapping DEGs were implicated in various biological processes, including protein metabolism, fatty acid metabolism, AMPK signaling, mTOR signaling, insulin/insulin-like growth factor signaling (IIS), the tricarboxylic acid (TCA) cycle, oxidative phosphorylation, and the cellular process of meiosis in oocytes. …”
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Bovine milk consumption affects the transcriptome of porcine adipose stem cells: Do exosomes play any role? by Katherine Swanson, Jimmy Bell, David Hendrix, Duo Jiang, Michelle Kutzler, Brandon Batty, Melanie Hanlon, Massimo Bionaz

“…The downregulation of insulin resistance and inflammatory-related pathways in the ASC of milk-fed pigs should be further explored in relation to milk and human health. …”
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Admission Hyperglycemia and Acute Myocardial Infarction: Outcomes and Potential Therapies for Diabetics and Nondiabetics by Anjan K. Chakrabarti, Priyamvada Singh, Lakshmi Gopalakrishnan, Varun Kumar, Meagan Elizabeth Doherty, Cassandra Abueg, Weici Wang, C. Michael Gibson

“…Studies that specifically investigated intensive insulin therapy, including DIGAMI-2 and HI-5, also failed to improve clinical outcomes such as mortality. …”
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Severe Diabetic Ketoacidosis in Children with Type 1 Diabetes: Ongoing Challenges in Care by Simone Foti Randazzese, Mariarosaria La Rocca, Bruno Bombaci, Alessandra Di Pisa, Elèna Giliberto, Teresa Inturri, Daniel Militi, Fortunato Lombardo, Eloisa Gitto, Giuseppina Salzano, Stefano Passanisi

“…Pathogenesis is linked to insulin deficiency and an excess of counter-regulatory hormones, which disrupt glucose, protein, and lipid metabolism, causing hyperglycemia, ketosis, acidosis, dehydration, and electrolyte imbalances. …”
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Initial Assessment of β-Adrenoceptor-Activated Brown Adipose Tissue in Streptozotocin-Induced Type 1 Diabetes Rodent Model Using [F]Fluorodeoxyglucose Positron Emission Tomography/... by Aparna Baranwal, M. Reza Mirbolooki, Jogeshwar Mukherjee

“…Further studies are needed to evaluate the therapeutic role of β3-adrenoceptor agonists in insulin-resistant T1DM.…”
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Characterization of Novel Nonobese Type 2 Diabetes Rat Model with Enlarged Kidneys by Ayaka Domon, Kentaro Katayama, Yuki Tochigi, Hiroetsu Suzuki

“…Oral glucose tolerance tests showed glucose intolerance and decreased insulin secretion in response to glucose loading in affected males, features which were exacerbated with age. …”
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The hidden impact: social isolation and inflammation’s role in pancreatic cancer risk among those with diabetes by Lilu Ding, Jing Qian, Ruoqi Dai, Hui Zhang, Jingyou Miao, Jing Wang, Min Yu, Xiao Tan, Yingjun Li

“…Baseline characteristics, insulin use, and other relevant factors were analyzed. …”
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Comparative effects of pravastatin and rosuvastatin on carbohydrate metabolism in an experimental diabetic rat model by Kaya Hacer Kayhan, Demirtas Berjan, Yokus Beran, Kesim Dilek Aygün, Tasdemir Ezel, Sermet Abdurrahman

“…At the end of the experiment, body masses, the levels of fasting blood glucose, serum insulin, insulin resistance (HOMA-IR), liver glycogen, and liver enzymes related to carbohydrate metabolism were measured. …”
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Glucagon-Like Peptide-1 Triggers Protective Pathways in Pancreatic Beta-Cells Exposed to Glycated Serum by Alessandra Puddu, Roberta Sanguineti, Arianna Durante, Alessio Nencioni, François Mach, Fabrizio Montecucco, Giorgio L. Viviani

“…AGEs negatively affect pancreatic beta-cell function and the expression of transcriptional factors regulating insulin gene. Glucagon-like peptide-1 (GLP-1), an incretin hormone that regulates glucose homeostasis, might counteract the harmful effects of AGEs on the beta cells in culture. …”
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Effect of light fasting diet therapy on lipid metabolism and sex hormone levels in patients with polycystic ovary syndrome combined with infertility by Xiaomei Jiang, Yongfeng Wang, Hong Tang, Jin Ma, Heyue Li

“…Differences in general clinical data, anthropometric indicators, follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), progesterone (P), fasting plasma glucose (FPG), fasting insulin (FINS), Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), total cholesterol (TC), triglycerides (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C)) were compared between the two groups.Results After treatment, both groups showed significant reductions in FSH, LH, E2, and P levels compared to baseline (p < .05). …”
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Changes in Serum Lipids and Blood Glucose in Non Diabetic Patients with Metabolic Syndrome after Mixed Meals of Different Composition by Adriana Branchi, Adriana Torri, Cristina Berra, Emanuela Colombo, Domenico Sommariva

“…Blood sugar similarly increased in both groups (19%, 2 hours after the meal in MetS+ and 17% in MetS−) and plasma insulin increased more and remained high longer in MetS+ (73.5 and 52.3 μU/mL, 2 and 4:30 hours after the meal) than in MetS− (46.7 and 21.6 μU/mL). …”
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Effect of weight loss on the course of non-alcoholic fatty liver disease: results of 6-month follow-up by L. V. Chesnokova, I. M. Petrov, I. A. Troshina, M. V. Goncharova, I. V. Medvedeva

“…Weight loss for 5% and over at steatosis stage of NAFLD is characterized by decrease ofbiochemical cardio-vascular risk markers, in addition the group with 40 min/day physical exercises inefficacy had lower level of insulin resistance index and TNF-α along with higher levels of NO metabolites.…”
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Relevance of Plasma Obestatin and Early Arteriosclerosis in Patients with Type 2 Diabetes Mellitus by Peng-ying Gu, Dong-mei Kang, Wei-dong Wang, Yan Chen, Zhi-hong Zhao, Hui Zheng, Shan-dong Ye

“…We found that higher levels of fasting insulin (Fins), fasting blood glucose, 2 h OGTT glucose, homeostasis model assessment of insulin resistance (HOMA-IR), low density lipoprotein cholesterol, glycated haemoglobin, and C-reactive protein (CRP), as well as lower obestatin level and higher intima-media thickness level (IMT), existed in T2DM group compared with NGT group and IGT group (P<0.01). …”
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Prevalence and associated factors of proliferative diabetic retinopathy among adult diabetic patients in Northwest Ethiopia, 2023: A cross-sectional multicenter study. by Abebech Fikade Shumye, Mebratu Mulusew Tegegne, Biruk Lelisa Eticha, Matiyas Mamo Bekele, Asamere Tsegaw Woredekal, Lakew Asmare

“…Hypertension, peripheral neuropathy, nephropathy, ≥10 year's duration of diabetic mellitus, insulin use and poor adherence to diabetes mellitus medications were among the factors significantly associated with proliferative diabetic retinopathy.…”
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