Diabetic Ketoacidosis as First Presentation of Latent Autoimmune Diabetes in Adult by Omar Nadhem, Essam Nakhla, Roger D. Smalligan

“…She was successfully treated with insulin with clinical and laboratory improvement. …”
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Infant of a diabetic mother: clinical presentation, diagnosis and treatment by Magdalena Suda-Całus, Katarzyna Dąbrowska, Ewa Gulczyńska

“…Less common complications in IDMs are: persistent pulmonary hypertension, hyperbilirubinemia, renal vein thrombosis, small left colon syndrome, intrauterine death, polycythemia, and a predisposition to obesity, insulin resistance and diabetes later in life. This article presents current knowledge about pathological conditions and the recommended management for IDMs.…”
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Progress in the Relationship between Vitamin D Deficiency and the Incidence of Type 1 Diabetes Mellitus in Children by Lian-Ping He, Yu-Xin Song, Ting Zhu, Wei Gu, Chang-Wei Liu

“…Type 1 diabetes mellitus (T1DM) is an autoimmune disease, due to a large number of islet β cells damaged, resulting in an absolute lack of insulin, ultimately relying on insulin therapy. Vitamin D is a fat-soluble sterol derivative that not only participates in calcium and phosphorus metabolism but also acts as an immunomodulatory role by binding to nuclear vitamin D receptors to regulate the expression of transcription factors. …”
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Chronic Sleep Disturbance Impairs Glucose Homeostasis in Rats by R. Paulien Barf, Peter Meerlo, Anton J. W. Scheurink

“…Data show that both RS and DS reduce body weight without affecting food intake and also lead to hyperglycemia and decreased insulin levels during an IVGTT. Acute sleep disturbance also caused hyperglycemia during an IVGTT, yet, without affecting the insulin response. …”
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Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes by Bahadır Ersan, Mahmut Ok

“…Fasting serum glucose, fructosamine, insulin, haemoglobin HbA1c, total cholesterol, triglyceride, urea, aspartate amino transferase and alanin amino transferase levels were measured.…”
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Acute Psychosis in Withdrawal from Nicotine Vaping in a Young Man with Comorbid Diabetic Ketoacidosis and Cannabis Use by Kyle J. Rutledge, Dianne L. Plath

“…The current report presents the case of a young man with multiple medical comorbidities, including insulin-dependent diabetes mellitus on an insulin pump and presumed Gilbert’s disease, and chronic cannabis use who experienced acute agitation with hallucinations in the context of quitting his vape pen “cold turkey” or abruptly discontinuing use without a nicotine replacement. …”
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Impact of Telephonic Reinforcement on Glycemic Control in Pediatric Type 1 Diabetes Mellitus: A Prospective Interventional Study at a Tertiary Healthcare Center by Reemu Bansal, Ambi Katyayani, Bala C. Bethamcherla, Lakshiya Ramamoorthy, Rajiv Ranjan, Lakshmi Murugesan, Nithila Sivakumar, Darshan K. Raj, Rishabh Jain

“…Introduction: Type 1 Diabetes Mellitus (T1DM) is a prevalent endocrine disease in children, requiring consistent management of diet, physical activity, insulin delivery, and glucose monitoring. Telemedicine has shown benefits for adults with chronic diseases, but its effectiveness for pediatric T1DM in India is less explored. …”
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The Effects of 6 Common Antidiabetic Drugs on Anti-PD1 Immune Checkpoint Inhibitor in Tumor Treatment by Ze-Tao Zhan, Lu Liu, Ming-Zhen Cheng, Yi Gao, Wei-Jie Zhou

“…Here, by employing syngeneic mouse colon cancer model and melanoma model, we studied the effects of 6 common antidiabetic drugs on anti-PD1 immune checkpoint inhibitor in tumor treatment, including acarbose, sitagliptin, metformin, glimepiride, pioglitazone, and insulin. We found that acarbose and sitagliptin enhanced the tumor inhibition of anti-PD1, and metformin had no effect on the tumor inhibition of anti-PD1, whereas glimepiride, pioglitazone, and insulin weakened the tumor inhibition of anti-PD1. …”
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Mesenchymal Stem Cells Ameliorate Hyperglycemia in Type I Diabetic Developing Male Rats by Hany N. Yousef, Samia M. Sakr, Sahar A. Sabry

“…Diabetic rats showed marked impairment (p<0.05) in serum levels of glucose, insulin, C-peptide, glycosylated hemoglobin (HbA1c), malondialdehyde (MDA), total antioxidant status (TAS), and total oxidant status (TOS) in addition to disruption of the calculated values of homeostatic model assessment of insulin resistance (HOMA-IR), pancreatic β cell function (HOMA-β), and oxidative stress index (OSI). …”
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Revascularization of Transplanted Pancreatic Islets and Role of the Transplantation Site by Andrew R. Pepper, Boris Gala-Lopez, Oliver Ziff, A. M. James Shapiro

“…Subsequently, despite the majority of patients achieving insulin independence after transplant, a proportion of them recommence small, supplemental exogenous insulin over time. …”
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Steatotic liver disease diagnosed in a 24-year-old woman with Rett syndrome: a case report by Larissa Albino, Adil Adatia, Aducio Thiesen, Brendan Halloran, Victor Dong, Carlos Moctezuma-Velázquez

“…Laboratory investigations excluded secondary causes, including insulin resistance, metabolic syndrome, alcohol use, and new medications. …”
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The role of oxidative stress, glucocorticoid receptor and ARMC5 in lipid metabolism by Yosuke Okuno, Atsunori Fukuhara, Iichiro Shimomura

“…Using genetically modified mice in which oxidative stress was eliminated or augmented specifically in adipose tissues, we have been able to elucidate that obesity-induced oxidative stress inhibited healthy adipose expansion and ameliorated insulin sensitivity. Using adipocyte-specific glucocorticoid receptor knockout mice, we found that glucocorticoids also inhibited healthy adipose expansion and decreased insulin sensitivity. …”
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Systematic Review of the Relationship Between Handgrip Strength and Blood Glucose Levels in Young Adults and the Elderly by Lekan Sheriff Ojulari, Swabirah Eniamire Sulaiman, Olayide Sulaiman Agodirin, Mohammed Amali

“…The suggested mechanisms involve insulin resistance, Caspase-3 activation, and the mitochondrial impact. …”
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Physical Activity and Blood Lipids and Lipoproteins in Dialysis Patients by Hiroyuki Imamura, Keiko Mizuuchi, Reika Oshikata

“…Examining studies on the effects of physical activity on blood lipids and lipoproteins, the most consistent observation is the noted decrease in triglycerides and increase in high-density-lipoprotein cholesterol and insulin sensitivity in hemodialysis patients. The changes in lipids and lipoproteins in hemodialysis patients could be caused by changes in activity levels of lipoprotein lipase, insulin sensitivity, and/or glucose metabolism. …”
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Effects of Melatonin on Adrenal Cortical Functions of Indian Goats under Thermal Stress by Veerasamy Sejian, Rajendra Swaroop Srivastava

“…Melatonin treatment at 11:00 AM significantly (P≤.05) influenced plasma levels of glucose, total protein, total cholesterol, cortisol, aldosterone and insulin. Metyrapone treatment aggravated thermal stress although administration of melatonin could ameliorate the condition. …”
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Paradoxical Glucose-Sensitizing yet Proinflammatory Effects of Acute ASP Administration in Mice by Alexandre Fisette, Pegah Poursharifi, Katerina Oikonomopoulou, Mercedes N. Munkonda, Marc Lapointe, Katherine Cianflone

“…ASP supplementation increased whole-body glucose excursion, and this was accomplished with reduced concomitant insulin levels. However, ASP did not directly alter insulin sensitivity. …”
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Ex Vivo Expansion of Murine MSC Impairs Transcription Factor-Induced Differentiation into Pancreatic β-Cells by Dario Gerace, Rosetta Martiniello-Wilks, Rosaline Habib, Binhai Ren, Najah Therese Nassif, Bronwyn Anne O’Brien, Ann Margaret Simpson

“…Ex vivo expanded MSCs were transduced with the HMD lentiviral vector (MOI = 10) to express furin-cleavable human insulin (INS-FUR) and murine NeuroD1 and Pdx1. This was followed by the characterization of pancreatic transdifferentiation via reverse transcriptase polymerase chain reaction (RT-PCR) and static and glucose-stimulated insulin secretion (GSIS). …”
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Mutational Analysis of KCNQ1 Gene in Type 2 Diabetes Mellitus: A Case-control Study by Ankush Ganjewar, Ishwar B Bagoji, Sharan Badiger, Rudragouda B Bulagouda, Gurushnatappa Kadakol

“…KCNQ1 is also associated with impaired insulin secretion in Type 2 Diabetes Mellitus (T2DM), suggesting that this impairment might underlie the diabetes susceptibility conferred by rs151290, which is associated with 30-min C-peptide levels during an Oral Glucose Tolerance Test (OGTT) and first-phase insulin secretion. …”
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Prospective study of the association between chronotype and cardiometabolic risk among Chinese young adults by Tingting Li, Yang Xie, Shuman Tao, Liwei Zou, Yajuan Yang, Fangbiao Tao, Xiaoyan Wu

“…Results Cross-sectional association analysis showed that lower MEQ-5 scores were correlated with higher fasting insulin (β=-1.420, 95%CI: -2.386~-0.453), higher HOMA-IR (β=-0.301, 95%CI: -0.507~-0.095), and higher CM risk score (β=-0.063, 95%CI: -0.122~-0.003), even after adjustment for covariates. …”
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Serum Fibroblast Growth Factor 21 Levels Are Positively Associated with Metabolic Syndrome in Patients with Type 2 Diabetes by Ruo-Yao Gao, Bang-Gee Hsu, Du-An Wu, Jia-Sian Hou, Ming-Chun Chen

“…Female gender, hypertension, systolic blood pressure (SBP), diastolic blood pressure (DBP), waist circumference (WC), body weight (BW), body mass index (BMI), body fat mass, fasting glucose, glycated hemoglobin level (HbA1c), triglyceride level (TG), urine albumin-to-creatinine ratio (UACR), insulin level, homeostasis model assessment of insulin resistance (HOMA-IR), and FGF21 levels were higher, whereas high-density lipoprotein cholesterol level (HDL-C) and estimated glomerular filtration rate (eGFR) were lower in DM patients with MetS. …”
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