Lipid-Induced Mechanisms of Metabolic Syndrome by Yulia K. Denisenko, Oxana Yu Kytikova, Tatyana P. Novgorodtseva, Marina V. Antonyuk, Tatyana A. Gvozdenko, Tatyana A. Kantur

“…Metabolic syndrome (MetS) has a worldwide tendency to increase and depends on many components, which explains the complexity of diagnosis, approaches to the prevention, and treatment of this pathology. Insulin resistance (IR) is the crucial cause of the MetS pathogenesis, which develops against the background of abdominal obesity. …”
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The Haematological Effects of Oleanolic Acid in Streptozotocin-Induced Diabetic Rats: Effects on Selected Markers by Charity M. Baloyi, A. Khathi, Ntethelelo H. Sibiya, Phikelelani S. Ngubane

“…Sustained hyperglycaemia leads to the development of haematological alterations which, if left untreated, is associated with cardiovascular complications. Insulin is the mainstay drug in type 1 diabetes mellitus (T1D); however, the use of insulin is associated with haematological alterations that could further worsen cardiovascular complications. …”
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Associated Factors with Biochemical Hypoglycemia during an Oral Glucose Tolerance Test in a Chinese Population by Xiaoling Cai, Xueyao Han, Xianghai Zhou, Lingli Zhou, Simin Zhang, Linong Ji

“…To find the association between biochemical hypoglycemia on a 2-hour screening oral glucose tolerance test (OGTT) and insulin resistance. Method. Subjects of this study were sampled from the China National Diabetes and Metabolic Disorders Study that was conducted during 2007 and 2008. …”
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Variations in Rodent Models of Type 1 Diabetes: Islet Morphology by Lesya Novikova, Irina V. Smirnova, Sonia Rawal, Abby L. Dotson, Stephen H. Benedict, Lisa Stehno-Bittel

“…Type 1 diabetes (T1D) is characterized by hyperglycemia due to lost or damaged islet insulin-producing β-cells. Rodent models of T1D result in hyperglycemia, but with different forms of islet deterioration. …”
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Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction by Zhen Wang, Chao Deng, Ying Zheng

“…As little is known about their role in insulin-secreting cells, this study is aimed at evaluating their contribution in the process of inflammation-induced β-cell damage. …”
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The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes by Basilio Pintaudi, Giacoma Di Vieste, Matteo Bonomo

“…Both myo-inositol and its isomer d-chiro-inositol showed insulin mimetic effects in conditions of insulin resistance. …”
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The Acute and Residual Effect of a Single Exercise Session on Meal Glucose Tolerance in Sedentary Young Adults by Kevin R. Short, Lauren V. Pratt, April M. Teague

“…There were strong test-retest correlations for the post-meal area under the curve (AUC) for glucose, insulin, and Cpeptide (r=0.73–0.83) and the Matsuda insulin sensitivity index (ISI, r=0.76), and between meal and IVGTT-derived ISI (r=0.83). …”
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Evaluation of the Association Metformin: Plantago ovata Husk in Diabetic Rabbits by Raquel Díez-Láiz, Juan J. García-Vieitez, M. José Diez-Liébana, Matilde Sierra-Vega, Ana M. Sahagún-Prieto, Ángela P. Calle-Pardo, Nélida Fernández-Martínez

“…We evaluated the use of Plantago ovata husk-metformin association in diabetic rabbits by determining its effects on glucose and insulin concentrations. Six groups of 6 rabbits were used. …”
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The impact of the novel starch-lipid complexes on the glucolipids metabolism, inflammation, and gut dysbiosis of type 2 diabetes mellitus rats by Yingshuang Lu, Renbing Qin, Jin Wang, Fengjuan Xiang, Yan Zhang, Bowei Zhang, Dancai Fan, Huan Lü, Xuemeng Ji, Shujun Wang, Shuo Wang

“…In addition, RS intake made an impact on phosphoinositide 3-kinase/protein kinase B signaling pathway that might contribute to the improvement of glucose metabolism, insulin resistance, and inflammatory responses.…”
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Therapeutic Potential of Ginger Ethanolic Extract, Ginger-Loaded Chitosan ‎Nanoparticles, and Chitosan Nanoparticles in Induced Type 2 Diabetes Mellitus in Dogss in Induced Type 2... by Rasema M Hameed, Alaa K Mahmood

“…Serum glycemic status (fasting serum glucose, insulin, and insulin resistance) was ‎recorded at baseline and on days 7, 14, 21, 28, 35, 42, and 45 post-treatments. ‎…”
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Possible Link between Metabolic Syndrome and Chronic Kidney Disease in the Development of Cardiovascular Disease by Kosaku Nitta

“…Visceral obesity and insulin resistance are two important features of MetS that may be associated with renal damage. …”
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High-Intensity Intermittent Exercise and Fat Loss by Stephen H. Boutcher

“…HIIE also significantly lowers insulin resistance and results in a number of skeletal muscle adaptations that result in enhanced skeletal muscle fat oxidation and improved glucose tolerance. …”
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Weight Considerations in Pharmacotherapy for Type 2 Diabetes by Vicky Cheng, Sangeeta R. Kashyap

“…Briefly, sulfonylureas, thiazolidinediones, and insulin are associated with weight gain, whereas metformin and amylin analogs are weight neutral or associated with modest weight loss. …”
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Role of T Lymphocytes in Type 2 Diabetes and Diabetes-Associated Inflammation by Chang Xia, Xiaoquan Rao, Jixin Zhong

“…Although a critical role of adaptive immune system has been confirmed in driving local and systemic inflammation in type 2 diabetes and promoting insulin resistance, the underlying mechanism is not completely understood. …”
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Severe Transient Hyperglycemia in a Prediabetic Patient during Mild Acute Pancreatitis by Aura Diana Reghina, Silvia Craciun, Simona Fica

“…A1c level was 5.9% without insulin treatment. The association between diabetes mellitus and acute pancreatitis is well established. …”
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Late remission in diabetes mellitus type 1. Presentation of a case. by Hiussymin Marchena Morera, Alina Esther González Hermida, Yanet Fragoso Cordero

“…<span style="language: es"><p>Diabetes mellitus type I is a chronic disease in which the deficit of insulin constitutes the fundamental element; its partial or total remission is frequently close to the moment of its premiere; reports of late remission don't exist which suggest that it is less frequent. …”
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The Association of Autoimmune Diseases with Type 1 Diabetes Mellitus in Children Depends Also by the Length of Partial Clinical Remission Phase (Honeymoon) by Gulsum Ozen, Angela Zanfardino, Santino Confetto, Alessia Piscopo, Francesca Casaburo, Nadia Tinto, Fernanda Iafusco, Gulsah Ozen, Emanuele Miraglia del Giudice, Medine Aysin Tasar, Arzu Yilmaz, Dario Iafusco

“…This is a transitory period that is characterized by insulin production by residual β cells following DM diagnosis and initiating the insulin therapy. …”
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Role of transforming growth factor-β1 in regulating adipocyte progenitors by Nguyen Quynh Phuong, Muhammad Bilal, Allah Nawaz, Le Duc Anh, Memoona, Muhammad Rahil Aslam, Sana Khalid, Tomonobu Kado, Yoshiyuki Watanabe, Ayumi Nishimura, Yoshiko Igarashi, Keisuke Okabe, Kenichi Hirabayashi, Seiji Yamamoto, Takashi Nakagawa, Hisashi Mori, Isao Usui, Shiho Fujisaka, Ryuji Hayashi, Kazuyuki Tobe

“…We used CD206CreERT2; Tgf-β1f/f mouse model in which the Tgf-β1 gene was conditionally deleted in CD206+ M2-like macrophages followed by tamoxifen administration, to investigate the role of the Tgf-β1 gene in glucose and insulin metabolism. Our data demonstrated that lack of CD206+ M2-like macrophages derived Tgf-β1 gene improved glucose metabolism and insulin sensitivity by enhancing adipogenesis via hyperplasia. …”
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The importance of stem cells in the treatment of type 1 diabetes, type 2 diabetes and diabetes complications by Monika Kamińska, Maria Jasiewicz, Magdalena Miernik-Skrzypczak, Aleksandra Spyra, Marta Malicka, Natalia Dąbrowska, Aleksandra Kozioł, Katarzyna Moczyróg

“…In type 2 diabetes, stem cell therapy improved insulin sensitivity and reduced insulin dependency, with evidence of β-cell regeneration. …”
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Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism by Ling Xiao, Dario F. De Jesus, Cheng-Wei Ju, Jiang-Bo Wei, Jiang Hu, Ava DiStefano-Forti, Valeria Salerno Gonzales, Tadataka Tsuji, Siying Wei, Matthias Blüher, Yu-Hua Tseng, Chuan He, Rohit N. Kulkarni

“…In humans and mice with insulin resistance, METTL14 expression differs significantly from BAT and WAT in the context of its correlation with insulin sensitivity. …”
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