New biomarkers for diagnosis of polycystic ovary syndrome by Farid I. Hassan, Mofeed F. Mohammed, Lamia H. Ali, Alaa A. M. Hussein

“…Results Mean value of triglycerides, low-density lipoprotein (LDL), total cholesterol, and very LDL had been greater between the cases group than the control one although there had been no variation among cases and controls regarding high density lipoprotein (HDL). Mean value of serum insulin and homeostasis model assessment-estimated insulin resistance (HOMA-IR) had been greater between cases group than the control. …”
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Development of a computational model of glucose toxicity in the progression of diabetes mellitus by Danilo T. Pérez-Rivera, Verónica L. Torres-Torres, Abraham E. Torres-Colón, Mayteé Cruz-Aponte

“…Diabetes mellitus is a disease characterized by a range of metabolic complications involving an individual's blood glucose levels, and its main regulator, insulin. These complications can vary largely from person to person depending on their current biophysical state. …”
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Severe palmoplantar keratoderma: a cutaneous complication from sub-optimally controlled type 2 diabetes by Fatima Iqbal, Kevin Phan, Wah N Cheung

“…Treatment included an insulin–dextrose infusion until DKA resolved, followed by twice daily insulin degludec/aspart (Ryzodeg 70/30) and metformin. …”
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In Vitro and In Vivo Improvement of Islet Quality and Transplantation Successes following Islet Treatment with Biomaterials in Diabetic Rats by Marzieh Nemati, Zahra Ebrahimi, Narges Karbalaei, Sanaz Dastghaib, Sara Khakshournia, Mojtaba Sargazi

“…Decreased level of glucose and MDA improved insulin level, increased SOD activity, and also enhanced pdx1 and insulin gene expression in diabetic rats after islet transplantation. …”
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Association between Circulating Ectodysplasin A and Diabetic Kidney Disease by Xia Deng, Chang Guo, Huijuan Qin, Li Zhao, Yanyan Li, Zhicong Zhao, Haoxiang Li, Ling Yang, Dong Wang, Guoyue Yuan

“…Insulin resistance and pancreatic cell function were assessed by HOMA. …”
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Obesity-Related Metabolic Syndrome: Mechanisms of Sympathetic Overactivity by Maria Paola Canale, Simone Manca di Villahermosa, Giuliana Martino, Valentina Rovella, Annalisa Noce, Antonino De Lorenzo, Nicola Di Daniele

“…This review focuses on current understanding of some mechanisms through which sympathetic overactivity may be interlaced to the metabolic syndrome, with particular regard to the role of insulin resistance and of some adipokines.…”
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Evaluation of Haematological and Immunological Status in Type 2 Diabetics by A. Sohna Chandra Packiavathy, M. Ramalingam

“…Type 2 diabetes is a heterogeneous disorder involving impairment of both insulin secretion and insulin action. The immunological and haematological statuses during normal and diseased conditions have been studied. …”
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Mechanisms Linking Vitamin D Deficiency to Impaired Metabolism: An Overview by Nurulmuna Mohd Ghozali, Nelli Giribabu, Naguib Salleh

“…Current evidence indicates that the deficiency of vitamin D could impair the pancreatic β-cell functions, thus compromising its insulin secretion. Besides, vitamin D deficiency could also exacerbate inflammation, oxidative stress, and apoptosis in the pancreas and many organs, which leads to insulin resistance. …”
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Beyond LDL cholesterol: remnant cholesterol is associated with cardiometabolic risk factors in children by Ana Torres-Costoso, Vicente Martínez-Vizcaíno, Andreia Oliveira, Mairena Sánchez-López, Eva Rodríguez-Gutiérrez, Sergio Núñez de Arenas-Arroyo, Montserrat Solera-Martínez, Blanca Notario-Pacheco, Vanessa Martínez-Madrid, Arthur Eumann Mesas

“…Methods Cardiometabolic risk factors (plasma insulin levels, homeostatic model assessment for insulin resistance, mean arterial blood pressure (MAP), waist circumference (WC), and cardiorespiratory fitness (CRF)) were examined in 3417 Spanish schoolchildren aged 8–11 years. …”
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Enterotype Bacteroides Is Associated with a High Risk in Patients with Diabetes: A Pilot Study by Jiajia Wang, Wenjuan Li, Chuan Wang, Lingshu Wang, Tianyi He, Huiqing Hu, Jia Song, Chen Cui, Jingting Qiao, Li Qing, Lili Li, Nan Zang, Kewei Wang, Chuanlong Wu, Lin Qi, Aixia Ma, Huizhen Zheng, Xinguo Hou, Fuqiang Liu, Li Chen

“…Multiple linear regression analysis was used to explore the relationship between lipopolysaccharide levels and insulin sensitivity after adjusting for age, BMI, TG, HDL-C, DAO, and TNF-α. …”
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The Polycystic Ovary Syndrome and the Metabolic Syndrome: A Possible Chronobiotic-Cytoprotective Adjuvant Therapy by Eduardo Spinedi, Daniel P. Cardinali

“…Although its etiology is not fully understood, evidence suggests that insulin resistance, with or without compensatory hyperinsulinemia, and hyperandrogenism are very common features of the polycystic ovary syndrome phenotype. …”
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Resistance Exercise Training-Induced Muscle Hypertrophy Was Associated with Reduction of Inflammatory Markers in Elderly Women by Kishiko Ogawa, Kiyoshi Sanada, Shuichi Machida, Mitsuharu Okutsu, Katsuhiko Suzuki

“…Muscle thickness and circulating levels of C-reactive protein (CRP), serum amyloid A (SAA), heat shock protein (HSP)70, tumor necrosis factor (TNF)-α, interleukin (IL)-1, IL-6, monocyte chemotactic protein (MCP-1), insulin, insulin-like growth factor (IGF)-I, and vascular endothelial growth factor (VEGF) were measured before and after the exercise training. …”
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Antihyperlipidemic Effects of Sesamum indicum L. in Rabbits Fed a High-Fat Diet by Sedigheh Asgary, Mahmoud Rafieian-Kopaei, Somayeh Najafi, Esfandiar Heidarian, Amirhossein Sahebkar

“…Serum concentrations of total cholesterol, LDL-C, HDL-C, triglycerides, apoA and apoB, SGOT, SGPT, glucose and insulin were measured at the end of supplementation period in all studied groups. …”
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Temporal Trends in Gestational Diabetes Prevalence, Treatment, and Outcomes at Aarhus University Hospital, Skejby, between 2004 and 2016 by Per Glud Ovesen, Jens Fuglsang, Mette Bisgaard Andersen, Charlotte Wolff, Olav Bjørn Petersen, H. David McIntyre

“…If the glycemic targets were not reached, insulin therapy was initiated. Birth weight and birth weight Z-score was calculated corrected for gender and gestational age at delivery. …”
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Angiotensin-Converting Enzyme 2 Deficiency Aggravates Glucose Intolerance via Impairment of Islet Microvascular Density in Mice with High-Fat Diet by Li Yuan, Ying Wang, Chunli Lu, Xiaoya Li

“…After 16 weeks of feeding, the islet function of the animals was evaluated by intraperitoneal glucose tolerance test (IPGTT) and intraperitoneal insulin releasing test (IPIRT). The pancreas was immunohistochemically stained to analyze the relative content of insulin (IRC), vascular endothelial growth factor (VEGF), and microvessel density (MVD) in islets. …”
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Adipocyte-Specific Fatty Acid-Binding Protein (AFABP) and Chemerin in Association with Gestational Diabetes: A Case-Control Study by Maryam Mosavat, Mitra Mirsanjari, Bashir A. Lwaleed, Maherah Kamarudin, Siti Zawiah Omar

“…These adipocytokines were related to insulin resistance, body mass index, and inflammation in pregnant women diagnosed with GDM.…”
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A trend of osteocalcin in diabetes mellitus research: bibliometric and visualization analysis by Zixu Liu, Zixu Liu, Yuchen Mao, Kangping Yang, Shukai Wang, Fang Zou

“…Analysis using the VoS viewer suggests a shift in research focus towards the correlation between osteocalcin levels and diabetic complications, the clinical efficacy of therapeutic agents or vitamins in the treatment of osteoporosis in diabetic patients, and the mechanisms by which osteocalcin modulates insulin action. The proposed focus areas are “osteocalcin genes”, “insulin regulation and osteoporosis “, “different populations”, “diabetes-related complications” and “type 2 diabetes mellitus”,“effect of osteocalcin expression on insulin sensitivity as well as secretion”,“osteocalcin expression in different populations of diabetic patients and treatment-related studies”.…”
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Influence of leptin administration to pregnant female mice on obesity development, taste preferences, and gene expression in the liver and muscles of their male and female offsprin... by E. I. Denisova, M. M. Savinkova, E. N. Makarova

“…An increase in blood leptin level in pregnant females reduces the risk of obesity and insulin resistance in the offspring, although the mechanisms mediating this effect are unknown. …”
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Characterization of the ZDSD Rat: A Translational Model for the Study of Metabolic Syndrome and Type 2 Diabetes by Richard G. Peterson, Charles V. Jackson, Karen Zimmerman, Willem de Winter, Norman Huebert, Michael K. Hansen

“…As disease progressed to overt diabetes, ZDSD rats demonstrated elevated glucose levels, abnormal oral glucose tolerance, increases in HbA1c levels, reductions in body weight, increased insulin resistance with decreasing insulin levels, and dyslipidemia. …”
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In Vivo Hypoglycaemic Effect and Inhibitory Mechanism of the Branch Bark Extract of the Mulberry on STZ-Induced Diabetic Mice by Hua-Yu Liu, Meng Fang, Yu-Qing Zhang

“…Obviously, mulberry BBE not only can reduce the abnormally elevated levels of serum insulin and ameliorate insulin resistance induced by STZ, but also it regulates dyslipidemia in diabetic mice. …”
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