Spermatic RXFP2 expression levels and seminal INSL3 concentrations among beef bull ejaculates with different levels of sperm morphological normality by Hewage Dilhan Anuradha WIMALARATHNE, Kenta ARASHI, Fumiyuki IWAKI, Mitsuhiro SAKASE, DURITAHALA, Hiroshi HARAYAMA, Noritoshi KAWATE

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Angiotensin IV Receptors in the Rat Prefrontal Cortex: Neuronal Expression and NMDA Inhibition by Zsolt Tamás Papp, Polett Ribiczey, Erzsébet Kató, Zsuzsanna E. Tóth, Zoltán V. Varga, Zoltán Giricz, Adrienn Hanuska, Mahmoud Al-Khrasani, Ákos Zsembery, Tibor Zelles, Laszlo G. Harsing, László Köles

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Features of conservative therapy of benign prostatic hyperplasia in patients with metabolic syndrome: " Treat to Target " by V. B. Filimonov, P. V. Vasin, V. N. Panchenko

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Impact of sex on the adaptation of adult mice to long consumption of sweet-fat diet by N. M. Bazhan, T. V. Iakovleva, A. D. Dubinina, E. N. Makarova

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SERT-Deficient Mice Fed Western Diet Reveal Altered Metabolic and Pro-Inflammatory Responses of the Liver: A Link to Abnormal Behaviors by Raymond Cespuglio, Anna Gorlova, Konstantin Zabegalov, Kirill Chaprov, Evgeniy Svirin, Kseniia Sitdikova, Alisa Burova, Boris Shulgin, Ksenia Lebedeva, Alexei V. Deikin, Sergey Morozov, Tatyana Strekalova

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Triglyceride to high density lipoprotein cholesterol ratio and major adverse cardiovascular events in ACS patients undergoing PCI by Shangxun Zhou, Miaohan Qiu, Kexin Wang, Jing Li, Yi Li, Yaling Han

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Biochemical Markers as Predictor of Preterm Labor - and Their Clinical Relevance - the Current Status by Suneeta Singh, Madhusudhan Dey, Sanjay Singh, Shibu Sasidharan

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Research status of ambulatory blood glucose monitoring in patients with type 2 diabetes mellitus (动态血糖监测在2型糖尿病患者中应用研究现状) by LIU MingLei (刘明磊), WU Quanying (武全莹), YU Shuyi (于淑一)

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Characterisation of IGF-1 (rs7136446) and IL-6 (rs1800795) polymorphisms among breast cancer patients in western Algeria by Fatima Zohraa Boussouf, Asmahane Medjdoub, Zineb Tahari, Moussa Messatfa, Noria Bouras, Chahinez Amira Dahmani, Sonia Amal Seddiki, Tewfik Sahraoui

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Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes by Xuebao Zhang, Kezhong Zhang

“…Diabetes mellitus (DM), a metabolic disorder characterized by hyperglycemia, is caused by insufficient insulin production due to excessive loss of pancreatic β cells (type I diabetes) or impaired insulin signaling due to peripheral insulin resistance (type II diabetes). …”
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Clinical and Functional Characteristics of a Novel KLF11 Cys354Phe Variant Involved in Maturity-Onset Diabetes of the Young by Yujing Sun, Jingru Qu, Jing Wang, Ruxing Zhao, Chuan Wang, Li Chen, Xinguo Hou

“…Luciferase reporter assays were used to investigate whether the KLF11 variant binds to the insulin promoter. Real-time PCR, western blotting, and glucose-stimulated insulin secretion (GSIS) analysis were used to analyze the KLF11 variant that regulates insulin expression and insulin secretion activity in beta cell lines. …”
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Cyclin-Dependent Kinase 5/p35/p39: A Novel and Imminent Therapeutic Target for Diabetes Mellitus by Danish Ahmed, Manju Sharma

“…Present therapies to minify hyperglycaemia and insulin resistance mainly target ATP-sensitive K+ channels (KATP) of pancreatic cells and PPAR-γ to enhance the insulin secretion and potential for GLUT expression, respectively. …”
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Acute Hyperglycemia Due to Topical Corticosteroid Administration by Laura Y. Sue, Anna Milanesi

“…We present the case of a 71-year-old man with longstanding, previously well-controlled type 1 diabetes who developed acute hyperglycemia. His insulin requirements, via his insulin pump, increased to nearly five times his typical daily dose. …”
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Diabetes Management and Outcomes among Patients with Type 2 Diabetes Attending a Renal Service by Elizabeth Skalkos, Rohit Rajagopal, David Simmons

“…Univariable analysis and multivariable logistic regression were used to identify factors associated with insulin treatment. Results. Among 268 patients (45.5% insulin-treated), mean HbA1c was higher in insulin-treated vs. noninsulin-treated patients (8.0±1.8% (64 mmol/mol) vs. 6.8±1.2% (51 mmol/mol), p<0.001). …”
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Differential risk of cardiovascular complications in patients with type-2 diabetes mellitus in Ghana: A hospital-based cross-sectional study. by Christian Obirikorang, Evans Asamoah Adu, Anthony Afum-Adjei Awuah, Samuel Nkansah Darko, Frank Naku Ghartey, Samuel Ametepe, Eric N Y Nyarko, Enoch Odame Anto, William Kwame Boakye Ansah Owiredu

“…These groups included the obesity-related phenotype, the severe insulin resistance phenotype, and the normal weight phenotype with improved insulin resistance. …”
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The Role of Visfatin, Leptin, and IL-18 in Polycystic Ovarian Syndrome Patients by Sukayna H. Rashed, Eman A. Hadi

“…The following biochemical variables were also evaluated: fasting blood sugar, fasting insulin, insulin resistance, leptin, visfatin, and IL-18. …”
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Effect of Gelam Honey on the Oxidative Stress-Induced Signaling Pathways in Pancreatic Hamster Cells by Kalaivani Batumalaie, Sher Zaman Safi, Kamaruddin Mohd Yusof, Ikram Shah Ismail, Shamala Devi Sekaran, Rajes Qvist

“…Cell lysate was collected to determine the effect of honey extracts and quercetin on the stress activated NF-κB, MAPK pathways, and the Akt (ser473) activated insulin signaling pathway. Results. HIT-T15 cells cultured under hyperglycemic conditions demonstrated insulin resistance with a significant increase in the levels of MAPK, NF-κB, and IRS-1 serine phosphorylation (ser307); however, Akt expression and insulin contents are significantly decreased. …”
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Detection of Islet Cell Immune Reactivity with Low Glycemic Index Foods: Is This a Concern for Type 1 Diabetes? by Datis Kharrazian, Martha Herbert, Aristo Vojdani

“…There was no immune reactivity between insulin or insulin receptor beta and dietary proteins. …”
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Metabolic Syndrome and Triple-Negative Breast Cancer: A New Paradigm by Andrew A. Davis, Virginia G. Kaklamani

“…The insulin-leptin-adiponectin axis has been implicated mechanistically in breast cancer tumorigenesis. …”
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Are obese rats influenced by GLP1 and IR through aerobic exercise? A case study by Ali Sayyah, Hamid Mohebbı, Hamid Arazı, Abbas Baharı

“…Glucagon-like peptide-1 (GLP-1) is characterized as incretion hormones secreted from the intestine upon ingestion of food to maximize insulin secretion, regulate blood sugar and enhance insulin resistance (IR). …”
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