Viscosol Treatment Ameliorates Insulin-Mediated Regulation of Dyslipidemia, Hepatic Steatosis, and Lipid Metabolism by Targeting PTP1B in Type-2 Diabetic Mice Model by Idrees Raza, Aamir Sohail, Hamza Muneer, Hajra Fayyaz, Zia Uddin, Amany I. Almars, Waheeb S. Aggad, Hailah M. Almohaimeed, Imran Ullah

“…Type 2 diabetes mellitus (T2DM), a metabolic disorder, has the hallmarks of persistent hyperglycemia, insulin resistance, and dyslipidemia. Protein-tyrosine phosphatase 1B (PTP1B) was found to be overexpressed in many tissues in the case of T2DM and involved in the negative regulation of insulin signaling. …”
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Comparison of GLP-1 Receptor Agonists, SGLT-2 Inhibitors, and DPP-4 Inhibitors as an Add-On Drug to Insulin Combined With Oral Hypoglycemic Drugs: Umbrella Review by Sanbao Chai, Yapin Niu, Fengqi Liu, Shanshan Wu, Zhirong Yang, Feng Sun

“…Conclusions: The combination of GLP-1 RAs, DPP-4i, and SGLT-2i can effectively lower HbA1c and FPG in T2DM patients who have poor therapeutic effects on basic insulin combined with metformin/sulfonylureas, respectively. …”
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Clinical characteristics of and growth hormone treatment effects on short stature with type 1 insulin-like growth factor receptor (IGF1R) gene alteration by Yuki Kawashima-Sonoyama, Keisuke Wada, Kei Yamamoto, Masanobu Fujimoto, Noriyuki Namba, Takeshi Taketani

Subjects: “…insulin-like growth factor 1 receptor (igf1r)…”
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Use of Blood Lipid Indicators as a Screening Tool of Insulin Resistance among Individuals in Low-Income Country Sides of China: A Multiethnic Region Study by Yi-Zhong Yan, Jia-Ning Fan, Jia-Ming Liu, Yun-hua Hu, Jiao-Long Ma, Jia He, Heng Guo, Xiang-hui Zhang, Xin-ping Wang, Shu-gang Li, Shu-Xia Guo

“…This study is aimed at evaluating the diagnostic value of blood lipid indicators (BLIs) for insulin resistance (IR) among major ethnic groups in Xinjiang, China, to identify the most valuable indicators and appropriate cut-off points for each ethnic group and to lay the foundation for the early detection, diagnosis, and treatment of metabolic diseases in remote rural areas. …”
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Comparison of single-point insulin sensitivity estimator (SPISE) index and cognitive performance in vitamin B12-deficient young adults: An analytical cross-sectional study by Himanshi Suri, K. A. Arul Senghor, V. M. Vinodhini, Koneru T. Sai, Jonathan Charles, S. Rooban

“…Based on SPISE index categorized as insulin resistant Group A <5.82 and non-insulin resistant Group B ≥5.82. …”
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Correlation between liver fibrosis in non-alcoholic fatty liver disease and insulin resistance indicators: a cross-sectional study from NHANES 2017–2020 by Bo Yang, Mingsu Gong, Xiaojie Zhu, Yang Luo, Ruiqiu Li, Hai Meng, Yuhan Wang

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Comparative effects of xylitol and erythritol on modulating blood glucose; inducing insulin secretion; reducing dyslipidemia and redox imbalance in a type 2 diabetes rat model by Nontokozo Z. Msomi, Ochuko L. Erukainure, Veronica F. Salau, Kolawole A. Olofinsan, Md. Shahidul Islam

“…In the present study, the effects of xylitol and erythritol were comparatively investigated on blood glucose, insulin level, dyslipidemia, pancreatic islet morphology and β-cell function, and redox imbalance in a type 2 diabetes (T2D) model of rats. …”
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Identification of Three Significant Genes Associated with Immune Cells Infiltration in Dysfunctional Adipose Tissue-Induced Insulin-Resistance of Obese Patients via Comprehensive Bioinformatics Analysis by Ming Zhai, Peipei Luan, Yefei Shi, Bo Li, Jianhua Kang, Fan Hu, Mingjie Li, Lei Du, Donglei Zhou, Weixia Jian, Wenhui Peng

“…Low-grade chronic inflammation in dysfunctional adipose tissue links obesity with insulin resistance through the activation of tissue-infiltrating immune cells. …”
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The imprinted Igf2-Igf2r axis is critical for exosome biogenesis during the early development of bovine placenta by Kunhua ZHENG, Longfei XIAO, Naihan YUAN, Xihui SHENG, Xiaolong QI, Yingqiu WANG, Chang CHEN, Kaijun GUO, Lin YANG, Bingying LIU, Xiangguo WANG

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Metabolic and inflammatory status in prepuberty and early adulthood for individuals with a history of extrauterine growth restriction: a cohort study by Laura Palomino-Fernández, Inmaculada Velasco, Belén Pastor-Villaescusa, Katherine Flores-Rojas, María de la Cruz Rico, Juan Roa, Ángel Gil, Mercedes Gil-Campos

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Association Between Triglyceride Glucose Index and Hypertension According to Different Diagnostic Criteria by Hao H, Geng H, Ma M

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Improvement of glucose metabolism in middle-aged mice on a high-fat diet by whole-grain highland barley is related to low methionine levels by Chuanxing Feng, Yueting Ge, Bowen Li, Xiangrong Cheng, Xue Tang, Jianjin Zhu, Yuge Jiang, Yonghui Shi, Guowei Le

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Assessment of six insulin resistance surrogate indexes for predicting stroke incidence in Chinese middle-aged and elderly populations with abnormal glucose metabolism: a nationwide prospective cohort study by Luqing Jiang, Tengxiao Zhu, Wenjing Song, Ying Zhai, Yu Tang, Fengxia Ruan, Zichen Xu, Lei Li, Xia Fu, Daoqin Liu, Aidong Chen, Qiwen Wu

Subjects: “…Insulin resistance surrogate index…”
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Indicators of Glucose Metabolism in Children and Adolescents Characterized as Having “Metabolically Healthy” and “Metabolically Unhealthy” Obesity by Maria Baltogianni, Niki Dermitzaki, Vasileios Giapros, Foteini Balomenou, Chrysoula Kosmeri, Fani Ladomenou, Evanthia Kantza, Anastasios Serbis

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Therapeutic role of isoflavones from traditional medicine in the management of polycystic ovary syndrome by Ashwini Armarkar, Prafulla Sabale, Satyendra Prasad, Vidya Sabale, Lata Potey, Dipti Masram

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Ursodeoxycholic acid in complex treatment of metabolic syndrome by O. A. Tanchenko, S. V. Naryshkina, O. N. Sivyakova

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Disorders of Adipose Tissue and Lipodystrophies: Causes, Consequences, and Treatment Perspectives by Rosińska Kamila Rosińska, Ewelina Justyna Janicka, Julia Natalia Skibicka, Monika Niedźwiedzka, Mateusz Rosiński

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Role of sirtuins in obesity and osteoporosis: molecular mechanisms and therapeutic targets by Yikuan Du, Yuying Huo, Yujia Yang, Peiqi Lin, Wuzheng Liu, Ziqin Wang, Wenqi Zeng, Jiahui Li, Zhonghan Liang, Chenyue Yuan, Jinfeng Zhu, Ziyi Luo, Yi Liu, Chunling Ma, Chun Yang

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Evaluation of the effects of short-term PM2.5 exposure on triglyceride-glucose metrics in a population in eastern China by Zhenpeng Guo, Chenchen Yang, Qiang Zhang, Xinling Shi, Xiaona Li, Qun Zhang, Jianming Wang

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Gut microbiota and endometrial cancer: research progress on the pathogenesis and application by Weiqin Zheng, Xiaowen Lin, Huixin Chen, Ziling Yang, Han Zhao, Shibo Li, Tao Song, Yuhui Sun

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