Expression of Heme Oxygenase-1 Mediated by A Protein Transduction Domain Protects Insulin Producing Cells from Cytokine- Induced Cytotoxicity by Melina Ribeiro, Dagmar Klein, Antonello Pileggi, R. Damaris Molano, CHristopher Fraker, Camillo Ricordi, Luca Inverardi

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JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression by Michala Prause, Christopher Michael Mayer, Caroline Brorsson, Klaus Stensgaard Frederiksen, Nils Billestrup, Joachim Størling, Thomas Mandrup-Poulsen

“…Utilizing Lentiviral mediated expression of shRNAs against JNK1, JNK2, or JNK3 in insulin-producing INS-1 cells, we investigated the role of individual JNK subtypes in IL-1β-induced β-cell apoptosis. …”
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High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report by Tsuyoshi Okura, Etsuko Ueta, Risa Nakamura, Yohei Fujioka, Keisuke Sumi, Kazuhisa Matsumoto, Kyoko Shoji, Kazuhiko Matsuzawa, Shoichiro Izawa, Yuri Nomi, Hitomi Mihara, Yuzuru Otsuka, Masahiko Kato, Shin-ichi Taniguchi, Kazuhiro Yamamoto

“…Advanced glycation end products (AGEs) are important in the pathophysiology of type 2 diabetes mellitus (T2DM). They directly cause insulin secretory defects in animal and cell culture models and may promote insulin resistance in nondiabetic subjects. …”
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Relationship between pelvic floor muscle function and insulin resistance among non-diabetic females: a 3d ultrasound evaluation by Lei Wang, Yunyun Cao, Ping Li, Ping He, Ping Chen

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Pilot Study of a Modified DOPS Scale for Insulin Pump and CGM Installation Training in Chinese Medical Students During Endocrinology Rotations by Yuan Y, Wang C, Wen S, Li Y, Xu C, Yu F, Li X, He Y, Chen L, Ren Y, Zhou L

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A Model of Insulin Resistance in Mice, Born to Diabetic Pregnancy, Is Associated with Alterations of Transcription-Related Genes in Pancreas and Epididymal Adipose Tissue by Akadiri Yessoufou, Kabirou Moutairou, Naim Akhtar Khan

“…This study is conducted on a model of insulin-resistant (IR) mice born to dams which were rendered diabetic by the administration of streptozotocin. …”
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TrkB Receptor Antagonism Enhances Insulin Secretion and Increases Pancreatic Islet Size in Rats Fed a Cafeteria-Style Diet by Jorge Agustín Velasco-Gutierrez, Elena Roces de Alvarez-Buylla, Sergio Montero, Alejandrina Rodríguez-Hernández, Saraí Limón Miranda, Karmina Martínez-Santillan, María del Rosario Álvarez-Valadez, Mónica Lemus, Alejandra Flores-Silva, Adolfo Virgen-Ortiz

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Effect of Green Tea Extract-Enriched Diets on Insulin and Leptin Levels, Oxidative Stress Parameters and Antioxidant Enzymes Activities in Obese Mice by Bártíková Hana, Boušová Iva, Matoušková Petra, Szotáková Barbora, Skálová Lenka

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Study on the Imprinting Status of Insulin-Like Growth Factor II (IGF-II) Gene in Villus during 6–10 Gestational Weeks by Jianhong Chen, Qun Fang, Baojiang Chen, Yi Zhou, Yanmin Luo

“…To compare the difference of imprinting status of insulin-like growth factor II (IGF-II) gene in villus between normal embryo development group and abnormal embryo development group and to investigate the relationship between karyotype and the imprinting status of IGF-II gene. …”
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Protocol of an Efficacy Study on Nursing Consultation in Weight Management and Metabolic Syndrome Based on the Carbohydrate–Insulin Theory in Individuals with First-Episode Psychosis by Lander Madaria, Claudia Aymerich, Ana Catalan, Miguel Angel Gonzalez-Torres

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Lignans from Patrinia scabiosaefolia improve insulin resistance by activating PI-3K/AKT pathway and promoting GLUT4 expression by Zhenhua Liu, Mengke Wang, Lijun Meng, Yixiao Chen, Qiuyi Wang, Yan Zhang, Xuefeng Xi, Wenyi Kang

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Metformin enhances epithelial cell growth inhibition via the protein kinase–insulin-like growth factor binding protein-1 pathway by Xuping Shao, Changling Li, Junhui Liang, Li Changzhong

“…Background Abnormal stromal-epithelial cell communication is a pathogenic mechanism in endometriosis, and metformin can modulate it. Insulin-like growth factor binding protein-1 (IGFBP1) plays a role in endometriosis, but the exact mechanism is unknown. …”
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Investigation of Insulin-Like Growth Factor 2 mRNA Binding Protein 2 Gene Polymorphisms in Type 2 Diabetes Patients by Duygu Yolal Ertural, Ümit Çınkır, Nurcan Aras

“…T2D is describes a group of clinical syndromes resulting from glucose metabolism disorders triggered by genetic or environmental factors. Insulin-like growth factor 2 mRNA binding protein 2 (IGF2BP2) gene participates in insulin signaling pathway and is involved in insulin secretion. …”
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Continuous Inhibition of Sonic Hedgehog Signaling Leads to Differentiation of Human-Induced Pluripotent Stem Cells into Functional Insulin-Producing β Cells by Song Lee, Jae Hyun Joo, Ju Yun Oh, Eun Ha Seo, Yang Hee Kim, Eunsung Jun, In Kyong Shim, Song Cheol Kim

“…Human-induced pluripotent stem cell- (iPSC-) derived insulin-producing cells (IPCs) can be used for islet cell transplantation into type 1 diabetic patients and as patient-specific cells for the development of novel antidiabetic drugs. …”
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Association between different insulin resistance indices and all-cause mortality in patients with diabetic kidney disease: a prospective cohort study by Huan Zhu, Yinmei Chen, Dexin Ding, Hui Chen

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Examining the Emotional and Physical Health Impact in Users of Open-Source Automated Insulin Delivery and Sources of Support: Qualitative Analysis of Patient Narratives by Bryan Cleal, Yanbing Chen, Mandy Wäldchen, Hanne Ballhausen, Drew Cooper, Shane O'Donnell, Christine Knoll, Niklas Krug, Klemens Raile, Tebbe Ubben, Adrian Tappe, Dana Lewis, Ingrid Willaing, Timothy Skinner, Katarina Braune

“… BackgroundAlthough commercially developed automated insulin delivery (AID) systems have recently been approved and become available in a limited number of countries, they are not universally available, accessible, or affordable. …”
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Severe obesity, high inflammation, insulin resistance with risks of all-cause mortality and all-site cancers, and potential modification by healthy lifestyles by Qianyun Jin, Siwen Liu, Yunmeng Zhang, Yuting Ji, Jie Wu, Hongyuan Duan, Xiaomin Liu, Jingjing Li, Yacong Zhang, Zhangyan Lyu, Fangfang Song, Fengju Song, Hua Li, Yubei Huang

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Camel milk and D-allulose synergistically improved camel dairy flavor and alleviated insulin resistance of human HepG2 cells by Tuerxunnayi Aili, Zhaoxu Xu, Chen Liu, Jie Yang, Haitao Yue

Subjects: “…Alleviated insulin resistance…”
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A Combined Therapy with Myo-Inositol and D-Chiro-Inositol Improves Endocrine Parameters and Insulin Resistance in PCOS Young Overweight Women by Elena Benelli, Scilla Del Ghianda, Caterina Di Cosmo, Massimo Tonacchera

“…Thus, we analyzed pretreatment and posttreatment FSH, LH, 17-beta-Estradiol, Sex Hormone Binding Globulin, androstenedione, free testosterone, dehydroepiandrosterone sulphate, HOMA index, and fasting glucose and insulin. Results. We recorded a statistically significant reduction of LH, free testosterone, fasting insulin, and HOMA index only in the group treated with the combined therapy of MI plus DCI; in the same patients, we observed a statistically significant increase of 17-beta-Estradiol levels. …”
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Expression of the Receptor for Advanced Glycation End Products in Epicardial Fat: Link with Tissue Thickness and Local Insulin Resistance in Coronary Artery Disease by Elena Dozio, Elena Vianello, Silvia Briganti, John Lamont, Lorenza Tacchini, Gerd Schmitz, Massimiliano Marco Corsi Romanelli

“…Our data suggest that in CAD patients RAGE may be involved in promoting EAT adiposity and metabolic dysfunction, such as impaired insulin signaling.…”
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