Anthropometric and metabolic parameters associated with visceral fat in non-obese type 2 diabetes individuals by Ming Jiao, Jiaoli Chen, Xiaoling Wang, Wenyu Tao, Yunhua Feng, Huijun Yang, Haiying Yang, Shanshan Zhao, Ying Yang, Yiping Li

“…Anthropometric and metabolic parameters were detected. Novel insulin resistance indices, such as lipid accumulation product (LAP) was calculated. …”
Get full text

Artificially Cultivated Ophiocordyceps sinensis Alleviates Diabetic Nephropathy and Its Podocyte Injury via Inhibiting P2X7R Expression and NLRP3 Inflammasome Activation by Chao Wang, Xiao-xia Hou, Hong-liang Rui, Li-jing Li, Jing Zhao, Min Yang, Li-jun Sun, Hong-rui Dong, Hong Cheng, Yi-Pu Chen

“…The DN rats showed to have developed insulin resistance, elevated fasting blood glucose, increased urinary protein excretion, and serum creatinine level as well as corresponding glomerular pathological alterations including podocyte damages. …”
Get full text

A bibliometric analysis of exosomes in aging from 2007 to 2023 by Zenghui Niu, Meiyu Cui, Yingkun Fu, Lingfeng Zhou, Jiali Wang, Jiali Wang, Yan Lei, Xinrong Fan, Qiang Wang, Jing Yang

“…The keyword analysis revealed that future research on exosomes in aging will possibly focus on “inflammation, cellular senescence, angiogenesis, insulin resistance, and Alzheimer's disease.”ConclusionWe identified the research trends of exosomes in the field of aging through this bibliometric analysis. …”
Get full text

Exploring the role of curcumin in mitigating oxidative stress to alleviate lipid metabolism disorders by Maojun Cheng, Maojun Cheng, Fang Ding, Fang Ding, Liyang Li, Liyang Li, Changmao Dai, Changmao Dai, Xiaolan Sun, Xiaolan Sun, Jia Xu, Jia Xu, Feier Chen, Feier Chen, Mingxiu Li, Xueping Li

“…These effects include decreasing fat deposition, increasing fatty acid uptake, and improving insulin sensitivity. A review of the existing literature reveals numerous studies emphasizing the role of curcumin in the prevention and management of metabolic diseases. …”
Get full text

Mir-483-5p-mediated activating of IGF2/H19 enhancer up-regulates IGF2/H19 expression via chromatin loops to promote the malignant progression of hepatocellular carcinoma by Weiwei Chen, Chutian Wu, Yuting Li, Tonghua Wang, Miaoling Huang, Min Wang, Linjing Long, Yanfang Chen, Shufen Feng, Xuyou Liu, Shaohui Tang

“…Abstract Background The insulin-like growth factor 2 (IGF2) and H19 are overexpressed in hepatocellular carcinoma (HCC). …”
Get full text

Genetic Analysis and Follow-Up of 25 Neonatal Diabetes Mellitus Patients in China by Bingyan Cao, Chunxiu Gong, Di Wu, Chaoxia Lu, Fang Liu, Xiaojing Liu, Yingxian Zhang, Yi Gu, Zhan Qi, Xiaoqiao Li, Min Liu, Wenjing Li, Chang Su, Xuejun Liang, Mei Feng

“…PNDM patients achieved good glycemic control with insulin or glyburide therapy. The etiology of NDM suggests polygenic inheritance.…”
Get full text

Pengaruh Pemberian Kefir Madu terhadap Profil Lipid Tikus Galur Sprague Dawley Sindroma Metabolik by Ibnu Malkan Bakhrul Ilmi, Angga Hardiansyah, Nikmatul Luailiya, Putri Aria Avrilian, Avliya Quratul Marjan, Dina Sugiyanti, Nur Hayati

“…Latar Belakang: Sindroma metabolik didefinisikan sebagai sekelompok gejala perubahan metabolik tubuh yang terjadi secara bersamaan yang terdiri dari obesitas sentral, dislipidemia, resistensi insulin, dan ketidakstabilan tekanan darah yang dapat diperbaiki melalui produk pangan fungsional. …”
Get full text

Prevalence of diabetes-related sarcopenia and its defining components within primary care: A cross-sectional study by Rubén Silva-Tinoco, Lilia Castillo-Martínez, Berenice Cabrera-Victoria, Eileen Guzmán-Olvera, Christian Hinojosa-Segura, Alejandro Avalos-Bracho, Cira Santillán-Díaz

“…Univariate logistic regression analysis identified that age, educational level, diabetes duration, weight, body mass index, waist circumference, hip circumference, fat mass, use, and insulin dose were associated with altered MF assessment. …”
Get full text

The potential impact of glycine supplementation on the process of aging by Michalina Wójcikiewicz, Julia Kulbacka, Witold Czyż, Julia Kacperczyk, Karol Dziedzic, Marta Chuncia-Ileczko, Maciej Wojszczyk, Damian Zys, Piotr Pasek, Julia Ryniecka, Wiktor Czaja, Michał Krzciuk

“…Emerging studies suggest that glycine supplementation may alleviate oxidative stress, dampen chronic low-grade inflammation, improve insulin sensitivity, enhance mitochondrial function, and even mimic aspects of methionine restriction- a dietary approach known to extend lifespan in animal models. …”
Get full text

Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Exposure to mixed NEOs during gestation resulted in elevated glucose levels and impaired insulin sensitivity in normal pregnant and GDM mice models. …”
Get full text

The levels of osteopontin in human milk of Chinese mothers and its associations with maternal body composition by Huijuan Ruan, Qingya Tang, Xuan Zhao, Yajie Zhang, Xuelin Zhao, Yi Xiang, Wei Geng, Yi Feng, Wei Cai

“…Serum glucocorticoid receptor α, adiponectin, insulin, and leptin were determined by ELISA. SPSS 25 was used for statistical analysis. …”
Get full text

CircPRMT5, a Potential Salivary Biomarker, Facilitates the Progression of Head and Neck Squamous Cell Carcinoma via the IGF2BP3-SERPINE1 Pathway by Jiang S, Ou L, Wang Y, Su K, Chen Z, He L, Xu X, Cheng B, Xia J, Fan Z

“…Mechanistically, circPRMT5 was demonstrated to directly bind to and stabilize the insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), which, subsequently, binds to and stabilizes the serpin family E member 1 (SERPINE1) mRNA, thereby enhancing SERPINE1 expression. …”
Get full text

Skeletal Status, Body Composition, and Glycaemic Control in Adolescents with Type 1 Diabetes Mellitus by Elzbieta Wierzbicka, Anna Swiercz, Pawel Pludowski, Maciej Jaworski, Mieczyslaw Szalecki

“…Disturbed bone turnover, osteoporosis, and increased fracture risk are late complications of insulin-dependent diabetes mellitus. Little is known about how far and to what extent can glycaemic control of type 1 diabetes mellitus (T1DM) prevent disturbances of bone health and body composition during the growth and maturation period. …”
Get full text

Association Between Triglyceride–Glucose Index and Carotid Plaque Stability in Different Glycemic Status: A Single‐Center Retrospective Study by Guijun Huo, Jin Zheng, Junjie Cao, Lili Zhang, Zhichao Yao, Yuqi Zeng, Yao Tang, Zhanao Liu, Ziyi Tan, Dayong Zhou

“…Background The triglyceride–glucose (TyG) index has been proposed as a reliable marker of insulin resistance. However, its value in patients with carotid plaque stability remains unclear. …”
Get full text

Empagliflozin-based quadruple oral therapy for type 2 diabetes: a prospective cohort study by Fatemeh Moosaie, Shiva Abedinzadeh, Soghra Rabizadeh, Kimia Daneshvar, Mohammadamin Noorafrooz, Fatemeh Alsadat Mojtahedi, Niloofar Deravi, Seyede Marzie Fatemi Abhari, Akam Ramezani, Alipasha Meysamie, Marzieh Hajibabaei, Sahar Karimpour Reyhan, Mahsa Abbaszadeh, Manouchehr Nakhjavani, Alireza Esteghamati

“…This prospective cohort study aimed to assess the effectiveness of Empagliflozin as part of a quadruple OHA regimen over a 7-year follow-up period in 575 adult patients with uncontrolled T2DM on a triple OHA regimen and who were unwilling to initiate insulin therapy. Overall, 92.5% of patients achieved their target HbA1c levels. …”
Get full text

The combined effect of metformin and mirabegron on diet‐induced obesity by Xin‐Yuan Zhao, Ying Liu, Xuan Zhang, Ben‐Chi Zhao, George Burley, Zhi‐Can Yang, Yi Luo, An‐Qi Li, Ruo‐Xin Zhang, Zhi‐Ying Liu, Yan‐Chuan Shi, Qiao‐Ping Wang

“…Additionally, Met/Mir improved glucose tolerance and insulin sensitivity. These benefits of Met/Mir were associated with increased EE, activated brown adipose tissue thermogenesis, and white adipose tissue browning. …”
Get full text

Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A rando... by Vernon Uganiza Rayo, Lauren Okamoto, Maricarmen Cervantes, Mee Young Hong, Nathaniel Jason, Mark Kern, Changqi Liu, Elise North, Svitlana Storm, Oliver C. Witard, Shirin Hooshmand

“…CONTROL (Trial: all p < 0.05). Insulin sensitivity decreased during CONTROL (Time: p < 0.05) but remained constant during ALMOND. …”
Get full text

Clinical Findings in Diabetes Mellitus Patients with COVID-19 by Ting Guo, Qinxue Shen, Xiaoli Ouyang, Wei Guo, Jinhua Li, Wenlong He, Bo Yu, Chenfang Wu, Zhiguo Zhou, Hong Luo, Hong Peng

“…Twelve DM patients (63.2%) changed diabetic therapy during hospitalization, and all DM patients admitted to the ICU used insulin. As of March 14, all 19 DM patients have been discharged, and no death occurred. …”
Get full text

LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype by Nadia Cobo‐Vuilleumier, Silvia Rodríguez‐Fernandez, Livia López‐Noriega, Petra I. Lorenzo, Jaime M. Franco, Christian C. Lachaud, Eugenia Martin Vazquez, Raquel Araujo Legido, Akaitz Dorronsoro, Raul López‐Férnandez‐Sobrino, Beatriz Fernández‐Santos, Carmen Espejo Serrano, Daniel Salas‐Lloret, Nila vanOverbeek, Mireia Ramos‐Rodriguez, Carmen Mateo‐Rodríguez, Lucia Hidalgo, Sandra Marin‐Canas, Rita Nano, Ana I. Arroba, Antonio Campos Caro, Alfred CO Vertegaal, Alejandro Martín‐Montalvo, Franz Martín, Manuel Aguilar‐Diosdado, Lorenzo Piemonti, Lorenzo Pasquali, Roman González Prieto, Maria Isabel García Sánchez, Decio L. Eizirik, Maria Asuncion Martínez‐Brocca, Marta Vives‐Pi, Benoit R. Gauthier

“…Abstract Background The complex aetiology of type 1 diabetes (T1D), characterised by a detrimental cross‐talk between the immune system and insulin‐producing beta cells, has hindered the development of effective disease‐modifying therapies. …”
Get full text

Potential use of beet-pulp concentrate supplementation in athletic horse by Luzilene Araujo de Souza, Monica Miranda Hunka, Sigismundo Fassbender de Rezende Júnior, Carolina Jones Ferreira Lima da Silva, Helena Emília Cavalcanti da Costa Cordeiro Manso, Joana Simões, Clarisse Simões Coelho, Francesco Fazio, Francesca Aragona, Hélio Cordeiro Manso Filho

“…Postprandial curves varied among challenges (p < 0.05) for glucose, insulin, and hematocrit. These results confirmed that BPC supplementation led to changes in blood biomarkers, without inducing major metabolic disruption. …”
Get full text