A two-sample bidirectional Mendelian randomization analysis between telomere length and hyperthyroidism by Shiben Zhu, Ziyu Hao, Qihang Chen, Xiaoliu Liu, Wenyan Wu, Fang Zhang

“…Utilizing 139 genome-wide significant single nucleotide polymorphisms (SNPs) as instrumental variables (IVs) for TL, forward MR analyses indicated a negative causal effect of TL on hyperthyroidism. …”
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Factors Associated with Poor Eye Drop Administration Technique and the Role of Patient Education among Hong Kong Elderly Population by Bonnie Nga Kwan Choy, Ming Ming Zhu, Jason Chun Sum Pang, Jonathan Cheuk Hung Chan, Alex Lap Ki Ng, Michelle Ching Yim Fan, Lawrence Pui Leung Iu, Joseph Shiu Kwong Kwan, Jimmy Shiu Ming Lai, Patrick Ka Chun Chiu

“…Questionnaires, including Barthel index; Lawton’s instrumental activities of daily living (ADL); Fatigue, Resistance, Ambulation, Illnesses, and Loss of Weight (FRAIL) scale; and Montreal Cognitive Assessment (MoCA), were used to correlate with eye drop application technique (before and after patient education) using Spearman correlation analysis. …”
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Occupational injuries, mental workload and coping strategies among the nursing workforce in the Eastern Region of Ghana: a multi-centre study by Collins Atta Poku, Abital Ayergo Ahulu, Janet Otomo, Doris Hagan, Catherine Kroamah Dwumfour, Joseph Shahadu Issifu, Veronica Dzomeku

“…The participants adopted different coping strategies in dealing with the mental workload, with active coping and instrumental support being the most used coping strategies. …”
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Clinical characteristics and usage of statins in patients with stable ischemic heart disease referred for angiography or coronary artery bypass grafting by I.V. Shklianka, O.J. Zharinov, К.O. Mikhaliev, O.A. Epanchintseva

“…At the same time, groups of patients who had been and had not been prescribed statins, did not differ by vast majority of demographic, clinical and instrumental characteristics, concomitant diseases and risk factors. …”
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Triggering the 2022 eruption of Mauna Loa by Kendra J. Lynn, Drew T. Downs, Frank A. Trusdell, Penny E. Wieser, Berenise Rangel, Baylee McDade, Alicia J. Hotovec-Ellis, Ninfa Bennington, Kyle R. Anderson, Dawn C. S. Ruth, Charlotte L. DeVitre, Andria P. Ellis, Patricia A. Nadeau, Laura Clor, Peter Kelly, Peter J. Dotray, Jefferson C. Chang

“…Careful correlation of both the geochemistry and instrumental monitoring data improves our ability to distinguish unrest from the run-up to eruption by providing deeper understanding of the both the monitoring data and the magmatic system—an approach that could be applied at other volcanic systems worldwide.…”
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Strengthening public health education and humanitarian response through academic volunteerism by Faiza Rab, Mekdes Assefa, Salim Sohani, Ilja Ormel, Farwa Arshad, Ahmad Firas Khalid

“…Methods We used a qualitative case study design with an instrumental approach. All documents related to academic volunteers within the CRC database from September 2018 to August 2023 were gathered and reviewed. …”
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Combined alverine citrate and simeticonein preparation in the treatment of irritable bowel syndrome by Ye. A. Poluektova, S. Yu. Kuchumova, V. T. Ivashkin

“…Retrospective analysis of efficacy and safety of meteospasmyl in 30 patients with IBS diagnosis, confirmed by conformity of complaints to Rome-III criteria and absence of pathological changes at laboratory and instrumental investigations was carried out. Thirteen patients had clinical pattern of diarrhea predominance (IBS-D), 17 – predominance of constipation (IBS-С). …”
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The Analysis on the Current Situation of the Utilization Mode of Microalgal Biomass Materials by Lina Zhang, Lianfeng Wang, Huizhong Nie, Changbin Liu

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SOBRE LOS CAMBIOS DE PERSPECTIVA EN EL CONOCIMIENTO by LUZ MARINA BARRETO

“…En este sentido, los cambios de perspectiva pueden ser entendidos como una posibilidad que sólo puede hacerse inteligible dentro de una noción unificada de la razón, una concepción que ha sido ignorada por concepciones epistemológicas que acentúan su lado instrumental y que podemos remontar a algunos conceptos de la ontología fenomenológica que han sido re-interpretados a través de la lente de la teoría de la experiencia kantiana. …”
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Metabolic syndrome and pancreatic lesions by O. S. Shifrin, I. A. Sokolina, A. E. Leonovich, M. A. Ashitko, T. L. Lemina, A. V. Korolyov

“…Original investigation algorithm was based on tasks of the study and included careful inquiry and physical investigation of patients. Laboratory and instrumental studies included: total and biochemical blood tests, lipid profile, coprological test, transabdominal and (under specific indications) endoscopic abdominal US, esophagogastroduodenoscopy (EGDS), computer tomography (CT) of abdominal organs, magnetic-resonance investigation (MRI).Results. …”
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Escala de Clima de Innovación: análisis psicométrico en trabajadores peruanos by Sergio Dominguez-Lara, Manuel Fernández-Arata, Patricia Bárrig-Jó

“…Por lo expuesto, esta investigación tuvo como objetivo analizar las propiedades psicométricas de la Escala de Clima de Innovación (ECI). El estudio instrumental se realizó en 273 trabajadores peruanos (50.916 % hombres) entre 22 y 76 años (Media = 45.224) pertenecientes en su mayoría a empresas privadas (75.092 %). …”
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aPD-L1-facilitated theranostic and tumor microenvironment remodeling of pancreatic cancer via docetaxel-loaded phase-transformation nanoparticles triggered by low-intensity pulsed... by Yi Tang, Qingling Shen, Peng Lin, Zhixin Chen, Denghui Fan, Minling Zhuo, Yajiao Gan, Yixi Su, Qingfu Qian, Liwu Lin, Ensheng Xue, Zhikui Chen

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A comparative analysis of sequence composition in different lots of a phage display peptide library during amplification by Anders Wilgaard Sinkjaer, Ane Beth Sloth, Amanda Oester Andersen, Malte Jensen, Babak Bakhshinejad, Andreas Kjaer

“…Our findings can be instrumental for phage display researchers by bringing fundamental insights into the vast extent of non-uniformity between phage display libraries and by providing a clear picture of how these discrepancies can lead to different evolutionary fates for the peptide composition of phage pools, which can have profound impacts on the outcome of phage display selections through biopanning.…”
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Genetic insight into dissecting the immunophenotypes and inflammatory profiles in the pathogenesis of Sjogren syndrome by Jingyi Xu, Shucheng Si, Yijun Han, Lin Zeng, Jinxia Zhao

“…We performed a bidirectional Mendelian randomization and mediation study based on randomly allocated instrumental variables to infer causality, followed by external validation with UK Biobank data and Bayesian colocalization. …”
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Assessment of aluminium level in commercial pasteurized and UHT milk in Bangladesh and their potential health risks by Ishrat Jahan, Kazi Md. Al-Noman, Shabbir Ahmed, Mst. Umme Habiba, S. A. Masudul Hoque, Abu Sadeque Md. Selim, Md. Morshedur Rahman

“…Milk samples from 10 brands, including three different production lots, were collected from supermarkets. The instrumental precision for Al was 0.0212 mg/kg as a limit of detection (LOD) and 0.0643 mg/kg as a limit of quantification (LOQ), with a relative standard deviation (RSD) of 3.2%. …”
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Moving beyond post hoc explainable artificial intelligence: a perspective paper on lessons learned from dynamical climate modeling by R. J. O'Loughlin, D. Li, R. Neale, T. A. O'Brien, T. A. O'Brien

“…We propose three types of understanding as a basis to evaluate trust in dynamical and AI models alike: (1) instrumental understanding, which is obtained when a model has passed a functional test; (2) statistical understanding, obtained when researchers can make sense of the modeling results using statistical techniques to identify input–output relationships; and (3) component-level understanding, which refers to modelers' ability to point to specific model components or parts in the model architecture as the culprit for erratic model behaviors or as the crucial reason why the model functions well. …”
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自发性脑出血术后早期使用阿司匹林的可能性：来自中国学者的首个脑出血围手术期管理高级别循证依据 Possibility of Early Use of Aspirin after Spontaneous Intracerebral Hemorrhage Surgery: The First High-Level Evidence-Based Evidenc... by 周航，陈高(ZHOU Hang, CHEN Gao)

“…As the first high-level evidence-based evidence on perioperative management of intracerebral hemorrhage in China, the E-start study is instrumental in improving the treatment and management standards for intracerebral hemorrhage and enhancing patient outcomes.…”
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Model analysis of biases in the satellite-diagnosed aerosol effect on the cloud liquid water path by H. Kokkola, H. Kokkola, J. Tonttila, S. M. Calderón, S. Romakkaniemi, A. Lipponen, A. Peräkorpi, T. Mielonen, E. Gryspeerdt, T. H. Virtanen, P. Kolmonen, A. Arola

“…Our comparison shows that spatial variability in cloud properties and instrumental noise in satellite retrievals of cloud optical depth and cloud effective radii results in bias in the satellite-derived liquid water path. …”
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Guidelines for the Management of Complications of Diabetes in Saudi Arabia Using Delphi Technique for Consensus Among National Experts by Raed Aldahash, Mohammed A. Batais, Ashraf El-Metwally, Saja Alhosan, Mohammed Alharbi, Mohammed Almutairi, Abdulghani Alsaeed, Mohammed Alsofiani, Mohammed AlMehthel, Mohammed Aldubayee, Khaled Aldossari, Sulieman Alshehri

“…The process concluded with a list of 37 statements about the management of acute and chronic complications of diabetes in Saudi Arabia. (4) Conclusions: The preparation of contextual evidence for the management of diabetes in Saudi Arabia will be instrumental in addressing the burden of disease in the region. …”
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Can real-time surveillance systems of suspected suicide accurately reflect national suicide rates? Age-specific and sex-specific findings from the first two years of the COVID-19 p... by Nav Kapur, Louis Appleby, Pauline Turnbull, Su-Gwan Tham, Saied Ibrahim, Cathryn Rodway

“…Early data on suspected suicides collected by local systems can be instrumental in reflecting national trends, and in aiding a rapid response in times of crisis.…”
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