Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade by Xiaolin Liu, Xiao Liu, Xiaonan Luo, Maorong Zhu, Nannan Liu, Juan Li, Qi Zhang, Cheng Zou, Yuxin Wu, Zhengcong Cao, Shuangxin Ma, Weizhong Wang, Guangzhao Yang, Jintao Gu, Wei Liu, Meng Li, Anan Yin, Yalong He, Wei Lin

“…As a result, there is a pressing need for innovative therapeutic approaches to combat GBM. Thus, we have developed an engineered multifunctional extracellular vesicle (EV) delivery system that offers an "all-in-one" strategy for GBM therapy. …”
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Integrating artificial intelligence into healthcare systems: opportunities and challenges by Bongs Lainjo

“…Research indicates that AI has transformed healthcare innovation, particularly in clinical decision support and personalized treatment. …”
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The Influence of Augmented Reality on Purchase Intention in the Housing Industry by F. A. Ibrahim, W. Boying, N. S. Abdul Rahim, M. W. Mohd Shafiei, N. Z. Zainol

“…In contrast, the advancement of technology was not thoroughly harnessed by the property sector, which lagged in adopting the innovative marketing approach to promote their selling house. …”
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Development of an intelligent virtual assistant for digitalization of Moroccan agriculture by Iounousse Jawad, Temsamani Omar

“…This paper presents the design, development, and implementation of an innovative text-to-text chatbot system aimed at digitalizing the agriculture sector in Morocco, with a focus on supporting Darija-speaking farmers. …”
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E-commerce big data processing based on an improved RBF model by Lu Qiuping

“…Addressing this critical issue, this study introduces an innovative approach employing a radial basis function neural network for predicting CC within the e-commerce sector. …”
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Nuclear Fusion Pattern Recognition by Ensemble Learning by G. Farias, E. Fabregas, I. Martínez, J. Vega, S. Dormido-Canto, H. Vargas

“…Specifically, AdaBoost algorithm will allow obtaining an explicit set of rules that explains the class for each input data, adding interpretability to the models. In this paper, an innovative approach to perform an online classification, that is, to identify the discharge before it actually ends, using interpretable models is presented. …”
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Characterization and Prediction of the Ghana Stock Exchange Composite Index Utilizing Bayesian Stochastic Volatility Models by Osei K. Tweneboah, Kwesi A. Ohene-Obeng, Maria C. Mariani

“…The paper then advances to predictive modeling, employing an innovative approach with four variations of Stochastic Volatility (SV) models: SV with linear regressors, SV with Student’s <i>t</i> errors, SV with leverage effects, and a hybrid model combining Student’s <i>t</i> errors with leverage. …”
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RecNet: Reinforcement Common Feature Mapping Network for Fast Template Matching in Visible-LWIR Images by Donyung Kim, Seungeon Lee, Inho Park, Geonjong Kim, Sungho Kim

“…We present RecNet, a novel end-to-end CNN approach for fast template matching in cross-spectral images, addressing nonlinear intensity disparities and appearance differences in ground-level imagery through a simple yet effective design. Our key innovation lies in the seamless integration of Zero-mean normalized cross correlation (ZNCC), which is well-validated for handling nonlinear intensity variations, with CNN-based shape difference learning. …”
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Environmental, economic and social trade-offs of membrane-based direct air capture technologies integrated with CO2 conversion using life cycle assessment by Tianhui Fan, Siyu Shen, Chun Yat (Benjamin) Sit, Paul J.A. Kenis, Andrew Chapman

“…Further technological innovation and efficiency gains will also close this gap, meaning that the membrane-based DAC-U concept may play a role in achieving carbon neutrality goals in the near future.…”
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Immunometabolism of Tregs: mechanisms, adaptability, and therapeutic implications in diseases by Yuming Lu, Yifan Wang, Tiantian Ruan, Yihan Wang, Linling Ju, Mengya Zhou, Luyin Liu, Dengfu Yao, Min Yao

“…This could contribute to restoring immune system balance, resolving metabolic dysregulation, and fostering innovation and progress in immunotherapy.…”
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Androgen receptor dynamics in prostate cancer: from disease progression to treatment resistance by Caihong Li, Dongkai Cheng, Peng Li

“…Additionally, basal cell-lumen-derived organoids provide innovative models that can enhance understanding and treatment strategies in prostate cancer.…”
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Microgravity Monitoring Technology for Deep Gas-Reservoir Development based on Dixi 121 Wellblock in Xinjiang Oilfield by Zongfang HU, Qingxiong HU, Yun CAI, Changrui ZHANG, Quandang SHI, Guihong XU, Jianqiang QIN, Yuangang XIE, Shenshen DENG, Hewen ZHU, Xue BAI

“…The application of microgravity technology to the development of gas reservoirs in the middle and deep reservoirs is achieved, and a sand-ground ratio forward model is innovatively established for the geological conditions of the study area to analyse the response of the sand thickness in the residual gravity anomaly field. …”
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Interference of a phytoconstituent from Nymphaea lotus-derived ligand N-acetyl glucosamine with signaling receptors in diabetes mellitus development: A targeted computational analy... by Sunday Amos Onikanni, Tran Nhat-Phong Dao, Adewale Oluwaseun Fadaka, Halliru Zailani, Oluwafemi Shittu Bakare, Omolola Esther Amos, Ashwil Klein, Valens Munyembaraga, Morenike Grace Ajayi, Adebola Iyabode Akinjokun, Babatunji Emmanuel Oyinloye, Leandro Miranda-Alves

“…Computer-aided drug design (CADD) is a powerful tool that has revolutionized the process of discovering and developing new drugs. It provides innovative methods that can speed up drug discovery and lower costs thereby results to increase enthusiasm at developing instinctive antidiabetic agents as alternatives for managing diabetes. …”
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Sub-suppliers model 4.0 and knowledge discovery in industry supply chain by Milena KRUMOVA, Evgeniy PETROV

“… Web 4.0 revolution and the abundance of industrial data in the current business environment allow each industrial company to innovate in a diversity of ways. The novelty approaches for the industry are often related to Industry 4.0, where data plays a key role. …”
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Discourse analysis of the representation of Hallaj's face in the works of Khwaja Abdullah Ansari by Mehrad Asad Paski, Ali Taslimi, Moamadkazem Yoosef Pour

“…His life was dedicated to writing hadith, guidance and anti-innovation. Like Hojviri and Qosheiri, he expounded some topics of Sufism in his works, and in line with this aim, the views of Hallaj were also reflected in these works as one of the crucial elements of Sufism. …”
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Integrated Detection of Respiration and Heartbeat With Communication Capabilities Using OFDM-LFM-MP Signals by Zhaoshen Dong, Yan Liu, Yukai Ouyang

“…To address the evolving demands of intelligent networks, integrated sensing and communication (ISAC) has emerged as a focal area of research. This encompasses innovative signal design, radar-based and communication hardware integration, and other vital directions. …”
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Hybrid Text Embedding and Evolutionary Algorithm Approach for Topic Clustering in Online Discussion Forums by Ibrahim Bouabdallaoui, Fatima Guerouate, Mohammed Sbihi

“…This study introduces an innovative methodology for topic clustering by combining text embedding techniques—Latent Dirichlet Allocation (LDA) and BERT—trained on a singular autoencoder. …”
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Temperature-Responsive Hybrid Composite with Zero Temperature Coefficient of Resistance for Wearable Thermotherapy Pads by Ji-Yoon Ahn, Dong-Kwan Lee, Min-Gi Kim, Won-Jin Kim, Sung-Hoon Park

“…In this study, we present a novel hybrid composite combining carbon nanotubes (CNTs) with NTC properties and carbon black (CB) with PTC properties to achieve a near-zero temperature coefficient of resistance (TCR) at an optimal ratio. This innovation enhances the safety and reliability of carbon-based polymer composites for wearable heating applications. …”
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Numerical Investigation of the Influence of Roof Fracturing Angle on the Stability of Gob-Side Entry Subjected to Dynamic Loading by Zhibiao Guo, Lei Zhang, Zhibo Ma, Feixiang Zhong, Jingchao Yu, Siming Wang

“…In order to increase the mining rate of underground coal resources, an innovative nonpillar underground coal mining approach (fracturing roofs to maintain entry (FRME)) has been widely applied in China. …”
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Improving Teacher Professional Commitment Through Empowerment, Compensation, and Self-Efficacy: A Correlation Study with SITOREM Analysis on Private Junior High School Teachers in... by Nurul Wahidah, Yuyun Elizabeth Patras, Ikhsan Ikhsan

“…The study showed that the research positively influenced empowerment (X1) with teacher innovation. (2) Then, the research hypothesis is that there is a positive influence of compensation on teacher professional commitment; (3) Based on the research hypothesis, there is a positive influence of self-efficacy on the commitment of the teacher profession; (4) Based on the research hypothesis, there is a positive influence of empowerment and compensation on teacher professional commitment; (5) Based on the research hypothesis, there is a positive influence of empowerment and self-efficacy on professional commitment; (6) Based on the research hypothesis, there is a positive influence of compensation and self-efficacy on teacher professional commitment; and (7) Based on the research hypothesis, there is a positive influence of empowerment, compensation, and self-efficacy together on teacher professional commitment. …”
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