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14701
Correlation of rivaroxaban solubility in mixed solvents for optimization of solubility using machine learning analysis and validation
Published 2025-02-01“…Solubility optimization is essential for the effective delivery and therapeutic performance of rivaroxaban, as its low aqueous solubility limits oral bioavailability and necessitates innovative approaches for drug formulation. The study explored the role of primary alcohols combined with dichloromethane in improving solubility, emphasizing their industrial relevance in crystallization, purification, and drug manufacturing processes. …”
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14702
Der Weg ist das Ziel
Published 2025-01-01“…Aufbauend auf diesen Überlegungen entstand an der Universität Hannover ein innovatives Seminarkonzept, um bereits für angehende Lehrkräfte einen Raum zu schaffen, sich mit eben diesen Anforderungen ressourcenorientiert auseinanderzusetzen und eigene Fähigkeiten zum Umgang zu entwickeln. …”
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14703
Resolving Covid-19 with Blockchain and AI
Published 2024-06-01“…In that review, many potential blockchain applications were discovered; however, the majority of them were still in their infancy, and it couldn’t yet be predicted how they could contribute to the fight against COVID-19 through the use of platforms, access kinds, and consensus algorithms. Modern innovations such as blockchain and artificial intelligence (AI) were shown to be promising in limiting the spread of a virus. …”
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14704
Enabling smart parking for smart cities using Internet of Things (IoT) and machine learning
Published 2025-01-01“…The second part is a camera in the car parks that distinguishes between vacant and available parking spaces and stores the data collected by the camera in the centralized database, enabling the real-time display of the nearest available parking spots on digital screens at entrance gates, significantly reducing the time and effort spent in locating parking spaces. Through this innovative solution, we aim to enhance urban mobility and alleviate the challenges associated with urban parking congestion, thereby resolving the problem of intelligent parking for smart cities with the help of machine learning.…”
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14705
Psychosocial volunteer support for older adults with cognitive impairment: development of MyCare Ageing using a codesign approach via action research
Published 2020-09-01“…MyCare Ageing is an innovative programme that meets an identified need from hospitals and consumers to support patients with dementia and/or delirium to improve psychosocial outcomes on discharge from hospital.…”
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14706
ANALYSIS OF METHODOLOGY AND MODELS OF STRATEGIC PLANNING OF LOCAL DEVELOPMENT IN BOSNIA AND HERZEGOVINA
Published 2012-11-01“…We believe that an appropriately adjusted model of strategic planning provides an advantage for local communities in innovative and cooperative approaches to the problems of local government units, with the tendency for defining priority areas and sectors, while different levels of government, scientific and development institutions at local and other levels and civil sectors should be involved in solving these problems. …”
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14707
In Vitro Control of Phytophthora infestans and Alternaria solani Using Crude Extracts and Essential Oils from Selected Plants
Published 2020-01-01“…Control of the two diseases is usually by use of synthetic fungicides which have a long residue effect and also contribute to environmental pollution. Innovative use of biocontrols may offer an eco-friendly and more sustainable solution. …”
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14708
Application of the Professional Psychological Quest in the Professional Training of Police Officers
Published 2021-03-01“…It is noted that in order to create the proper conditions for the formation of future police officers professional competence, motivational focus on positive personal changes and the desire for professional self-development, it is advisable to use the possibilities of innovative teaching technologies, in particular, trainings and quests. …”
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14709
The Role of ChatGPT and AI Chatbots in Optimizing Antibiotic Therapy: A Comprehensive Narrative Review
Published 2025-01-01“…<b>Background/Objectives:</b> Antimicrobial resistance represents a growing global health crisis, demanding innovative approaches to improve antibiotic stewardship. …”
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14710
Nonlinear Constitutive Model of High-Temperature Viscoelastic Deformation of Gussasphalt Concrete
Published 2022-01-01“…To accurately evaluate the high-temperature stability of cast asphalt concrete, based on the traditional viscoelastic mechanical model, this paper innovatively improves the traditional viscoelastic mechanical model considering the conditions of temperature and dynamic load and deduces the viscoelastic constitutive model of high-temperature deformation performance of cast asphalt concrete, using a dynamic penetration test (DPT) to regress improved the Burgers model parameters and verify the model’s applicability and reliability. …”
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14711
Transcranial Direct Current Stimulation (tDCS) in Unilateral Cerebral Palsy: A Pilot Study of Motor Effect
Published 2019-01-01“…This study provides an innovative contribution to scientific literature on the efficacy and safety of anodal tDCS in UCP. …”
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14712
The fundamentals of Indian personality: An investigation of the big five
Published 2023-10-01“…The five factors were named as – Social Effectiveness, Interpersonal Ability, Altruism, Emotional Instability, and Innovativeness. The translated tool showed good temporal stability. …”
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14713
Advances in Illuminating Prostate Cancer with Emerging Phototherapies
Published 2025-01-01“…This review explores the recent innovations in illuminating prostate cancer with phototherapies, their combination with conventional therapies, and their clinical potential in reducing the global prostate cancer burden.…”
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14714
Chinese stroke association guidelines on reperfusion therapy for acute ischaemic stroke 2024
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14715
HDN-DDI: a novel framework for predicting drug-drug interactions using hierarchical molecular graphs and enhanced dual-view representation learning
Published 2025-01-01“…HDN-DDI integrates an explainable substructure extraction module to decompose drug molecules and represents them using innovative hierarchical molecular graphs, which effectively incorporates information from real chemical substructures and improves molecules encoding efficiency. …”
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14716
Bone Mineral Density Prediction from CT Image: A Novel Approach using ANN
Published 2023-01-01“…This paper presents an innovative approach for the prediction of BMD incorporating bone architecture that involves no extra cost, time, and exposure to severe radiation. …”
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14717
Exploring natural convection and heat transfer dynamics of Al2O3-H2O nanofluid in a modified tooth-shaped cavity configuration
Published 2025-01-01“…Incorporating Al2O3-H2O nanofluid enhances HT performance, especially at larger φ.Conclusion: The study concludes that the innovative design approach involving the wavy top wall, heated RVW, and adiabatic circular cylinder significantly influences the heat transfer and flow field within the cavity. …”
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14718
Asking the classroom with technology: a systematic literature review
Published 2025-01-01“…Still, few studies reported insignificant learning outcomes due to the digital divide, deficiency of proper infrastructure, limited support for innovative practices, lack of compatibility with other existing platforms, and inadequate digital literacy. …”
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14719
The role of technology in the strategic planning of international companies: digital transformation and efficiency
Published 2024-06-01“…Highlighting the significance and impact of digital innovations on strategic planning, the article also offers an in-depth consideration of the possibilities of using modern technologies in decision-making and strategy development, in particular in the form of introducing analytical systems, to improve the efficiency of strategic and operational activities of international companies. …”
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14720
Modified CD15/CD16-CLL1 inhibitory CAR-T cells for mitigating granulocytopenia toxicities in the treatment of acute myeloid leukemia
Published 2025-02-01“…In conclusion, we have successfully engineered innovative CD16-CLL1 iCAR-T cells, which preserves the cytotoxicity against tumor cells while preventing elimination of neutrophils, thereby significantly reducing the incidence of granulocytopenia during CAR-T therapy. …”
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