An Assay System for Plate-based Detection of Endogenous Peptide:N-glycanase/NGLY1 Activity Using A Fluorescence-based Probe by Hiroto Hirayama, Tadashi Suzuki

“…We recently advanced this approach by producing a novel fluorescence resonance energy transfer (FRET)-based GCP probe (fGCP) and demonstrated its ability to detect endogenous NGLY1 activity across diverse enzyme sources via fluorescence on multiarray plates. This innovative and straightforward assay now offers reliable disease diagnostics and also allows the measurement of endogenous PNGase/NGLY1 activities across various organisms.…”
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Postgraduate Professional Education in China: The State and Development Trends by S. S. Donetskaya, Bing Wang

“…This success has been achieved thanks to the creation of technological enterprises and the widespread introduction of innovations aimed at increasing labor productivity and making efficient use of other factors of production. …”
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Electrochemical conversion of methane measured by anode out gas monitoring over Ce–Co–Cu anode electrocatalysts by Bernardo Jordão Moreira Sarruf, Robert Steinberger-Wilckens, Paulo Emílio Valadão de Miranda

“…Gas chromatography was employed to monitor anode effluent gases under electrochemical conditions, complemented by electrochemical impedance assessments using hydrogen as the fuel to identify polarisation sources within these innovative anode configurations. The findings reveal that tracking chemical and electrochemical reactions in SOFCs provides insights into efficiency and fuel conversion mechanisms, wherein the anode material transforms fuel into useful products while generating electricity and heat. …”
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Impact of choline choride and sugar natural deep eutectic solvents on structure and functionality of treebean (Parkia timoriana) seed protein by Prostuti Chakravorty, Amit Baran Das

“…The novelty of the study lies in demonstrating the potential of NADES to sustainably enhance the structural and functional attributes of plant proteins, paving the way for innovative applications in food and bioprocessing industries. …”
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Dual-Mode Textile Sensor Based on PEDOT:PSS/SWCNTs Composites for Pressure–Temperature Detection by Ying Wang, Qingchao Zhang, Zhidong Zhang

“…As an innovative branch of electronics, intelligent electronic textiles (e-textiles) have broad prospects in applications such as e-skin, human–computer interaction, and smart homes. …”
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DockCADD: A streamlined in silico pipeline for the identification of potent ribosomal S6 Kinase 2 (RSK2) inhibitors by El Mehdi Karim, Meriem Khedraoui, Abdelkbir Errougui, Yasir S. Raouf, Abdelouahid Samadi, Samir Chtita

“…The search for innovative therapeutic strategies remains critical in addressing cancer, one of the leading global health challenges. …”
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Transcriptomic HIV-1 reservoir profiling reveals a role for mitochondrial functionality in HIV-1 latency. by Shirley Man, Jade Jansen, Stefanie Kroeze, Teunis B H Geijtenbeek, Neeltje A Kootstra

“…Here we developed an innovative flow cytometry-fluorescent in situ hybridization (flow-FISH) approach for direct ex vivo reservoir detection without the need for reactivation using a combination of probes detecting abortive and elongated HIV-1 transcripts. …”
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Global Perspectives on Laptop Features: A Sentiment Analysis of User Preferences in Developed and Developing Countries by Mehrdad Maghsoudi, Mohammadreza Bakhtiari, Hamidreza Bakhtiari

“…Based on these insights, the study proposes tailored strategies for laptop manufacturers, including differentiated product lines, universal charging solutions, and market-specific innovations in cooling systems and warranties. The methodology incorporates data preprocessing, ABSA implementation using the PyABSA framework, and a three-phase Delphi process for expert analysis. …”
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Screening of native wild Salvia nemorosa populations for chemical compositions, antioxidant activity and UHPLC-HRMS profiling by Raheleh Moshari-Nasirkandi, Abolfazl Alirezalu, Hamid Reza Mohammaddoust Chamanabad, Jussara Amato, Hadi Alipour, Ali Asghari, Atefeh Moshari-Nasirkandi

“…These findings suggest that the S. nemorosa populations studied here have significant potential for the development of innovative nutraceuticals, addressing the current scarcity of S. nemorosa-derived products in the market.…”
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Drying Kinetics and Changes of Total Phenolic Content, Antioxidant Activity and Color Parameters of Mango and Avocado Pulp in Refractance Window Drying by Thi-Van-Linh Nguyen, Quoc-Duy Nguyen, Phuoc-Bao-Duy Nguyen

“…Refractance window drying is an innovative technology belonging to the fourth generation of drying technologies that could enhance the quality of the dried product and improve the drying process. …”
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Strategic enhancement of joint strength in dissimilar Al/Mg alloys: a workable approach for aerospace application by S. Suresh, Elango Natarajan, Kalaimani Markandan, S. Sudhagar, Gnanasambandam Anbuchezhiyan, R. Elayaraja

“…However, the challenges associated with joining these dissimilar metals necessitate innovative solutions. This study explores the role of silicon carbide (SiC) nanoparticles in enhancing the friction stir spot welding (FSSW) of dissimilar alloys AA6061 and AZ31B. …”
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The GeoTox Package: open-source software for connecting spatiotemporal exposure to individual and population-level risk by Kyle P. Messier, David M. Reif, Skylar W. Marvel

“…Abstract Background Comprehensive environmental risk characterization, encompassing physical, chemical, social, ecological, and lifestyle stressors, necessitates innovative approaches to handle the escalating complexity. …”
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Analysis of Necessity and Feasibility for Ground Improvement in Warm and Ice-Rich Permafrost Regions by Honglei Wang, Hu Zhang, Mingtang Chai, Jianming Zhang, Zhizhong Sun, Guoyu Li

“…Based on the key factors determining the physicomechanical properties of frozen soil, an innovative idea of stabilizing the warm and ice-rich frozen soil based on chemical stabilization is proposed in this study, and then, an in situ ground improvement technique is introduced. …”
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Unraveling the protein kinase C/NDRG1 signaling network in breast cancer by C. Saponaro, M. Damato, E. Stanca, S. Aboulouard, F. A. Zito, S. De Summa, D. Traversa, L. Schirosi, S. Bravaccini, F. Pirini, E. Fonzi, M. Tebaldi, M. Puccetti, A. Gaballo, L. Pantalone, M. Ronci, L. Magnani, D. Sergi, A. Tinelli, S. Tacconi, L. Siculella, A. M. Giudetti, I. Fournier, M. Salzet, M. Trerotola, D. Vergara

“…Together, our findings highlight the potential of NDRG1 as a new BC biomarker and uncover a novel mechanism of regulation of NDRG1 expression that might lead to innovative therapeutic strategies.…”
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Advances of research in diabetic cardiomyopathy: diagnosis and the emerging application of sequencing by Qianqian He, Ze Lai, Zhengyao Zhai, Beibei Zou, Yangkai Shi, Chao Feng

“…Thus, it becomes imperative to uncover innovative approaches to facilitate the prompt identification and diagnosis of DCM. …”
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SpikeMOT: Event-Based Multi-Object Tracking With Sparse Motion Features by Song Wang, Zhu Wang, Can Li, Xiaojuan Qi, Hayden Kwok-Hay So

“…To address these limitations, we introduce SpikeMOT, an innovative event-based MOT framework employing spiking neural networks (SNNs) within a Siamese architecture. …”
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Exploring Nexus between food security and the loss of agro-biodiversity: a study in Madhya Nepal, Lamjung by Binita Shahi, Shudarshan Hamal, Leela Raj Upadhyay

“…Integrating traditional knowledge with scientific innovations is crucial for sustainable food production. …”
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A Lane Change Strategy to Enhance Traffic Safety in the Coexistence of Autonomous Vehicles and Manual Vehicles by Young Jo, Cheol Oh

“…The purpose of this study is to develop a Proactive Lane-changE Assistant Strategy for Automated iNnovative Transportation (PLEASANT) to enhance traffic safety. …”
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Integrating problem-based learning in e-lkpd: Enhancing problem-solving ability and adversity quotients by Thitra Padma Rani, Sugeng Sutiarso, Rangga Firdaus

“…Conclusion: The PBL-based E-LKPD has been proven valid, practical, and effective in enhancing students' mathematical problem-solving abilities and adversity quotient, making it a viable and innovative alternative in the learning process.…”
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Is Objective Structured Practical Examination a Better Option than Conventional Practical Examination in Assessing Students’ Competency? An Analytical Research by Arup J. Rout, Pallabi Dasgupta, Tushar K. Saha, Daliya Biswas

“…Background: There was always a need for some innovative assessment method like an objective structured practical examination (OSPE) which is objective, reliable, and valid over conventional practical examinations (CPEs), which lack objectivity and reliability and carries risk of teachers’ bias as learning is assessment-driven. …”
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