New therapies in pulmonary arterial hypertension: Recent insights by Giulia Guglielmi, Konstantinos Dimopoulos, S. John Wort

“…This is a review of recent advances in the development of innovative therapeutic strategies for PAH.The first section of this paper explores approaches targeting TGF-β signalling, both acting directly on receptors through drugs like Sotatercept and exogenous BMP9, and indirectly, inhibiting the degradation of key receptors, such as BMPR2. …”
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Understanding Rett Syndrome: Genetic, clinical and therapeutic perspectives - literature review by Sylwia Urbańska, Aleksandra Witas, Martyna Borowska-Łygan, Justyna Pięta

“…Summary: The authors highlight the need for development of early diagnosis of RTT in infants, rehabilitation focused on family-centred care (FCC) and the need for further research towards innovative treatments for Rett Syndrome. …”
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Research on Dynamic Monitoring and Early Warning of the High-Rise Building Machine during the Climbing Stage by Xi Pan, Zibo Zuo, Longlong Zhang, Tingsheng Zhao

“…In this study, the key factors influencing the climbing altitude were systematically analyzed and a method for the dynamic monitoring and early warning of HBMs during climbing was proposed. This approach is innovative for monitoring 3D attitude in real time using a string of fiber grating-level sensors mounted on the main bearing surface of the HBM. …”
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Optimization Design and Simulation of Single Degree of Freedom Legs of Quadruped Robots by Shi Huiwen, He Jing, Wang Zhijun

“…The optimal design method of the multi-link leg mechanism composed of two crank-rocker mechanisms provides a basis and innovative ideas for the leg design of legged robots.…”
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Metformin-induced mitophagy suppresses auditory hair cell apoptosis via AMPK pathway by Yifan Lai, Jiawei Qiu, Kuang Zheng, Xiang Li, Yinuo Lin, Zhengzheng Li, Haiqiu Sun

“…Overall, our results suggest that metformin may represent a promising and innovative therapeutic strategy for mitigating the onset of hearing loss.…”
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On the development of diagnostic support algorithms based on CPET biosignals data via machine learning and wavelets by Rafael F. Pinheiro, Rui Fonseca-Pinto

“…Leveraging support vector machine (SVM) technology, a well-known machine learning classification method, in combination with wavelet transforms for feature extraction, the algorithm takes an innovative approach. The model was trained on CPET data from 45 participants, including 15 with MS, 15 with HF, and 15 healthy controls. …”
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Artificial neural networks analysis for non-newtonian nanofluid flow with variable viscosity and MHD effects in wire covering processes by Maria Altaib Badawi, Zeeshan, Nehad Ali Shah, Imed Boukhris, Adel Thaljaoui

“…In the realm of artificial neural networks, the Levenberg-Marquardt Algorithm is characterized by its innovative stability and produces a computational resolution of the wire covering for third grade nanofluid flow (WC-TGNFF) utilizing regression plots (RP), histogram visualizations, state transition metrics, and mean squared errors (MSE). …”
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A Straightforward Approach of Wet‐Spinning Poly(3,4‐ethylenedioxythiophene):Polystyrene Sulfate Fibers for Use in All Conducting Polymer‐Based Textile Actuators by Mathis Bruns, Shayan Mehraeen, Jose G. Martinez, Johannes Mersch, Iris Kruppke, Edwin W. H. Jager, Chokri Cherif

“…Poly(3,4‐ethylenedioxythiophene) (PEDOT), an inherently electrically conductive or conjugated polymer (CP), exhibits the potential to play a significant role in the development of innovative fiber materials for use in smart textiles, such as wearables. …”
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TREATMENT OF RIVER AND LAKE WATER FOR ALGAE USING NANOBUBBLES by Dan Ovidiu Cîrjan, Maria Stoicescu

“…This study explores the innovative use of nanobubbles in treating river and lake water, focusing on the removal of algae and other organic pollutants. …”
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Ecofriendly dyeing of silk fabric with yellow natural and synthetic dye by Hamid Ali Tanveer, Shahid Adeel, Fazal-ur-Rehman, Muhammad Ibrahim, Al Mojnun Shamim, Muhammad Aftab, Muhammad Imran, Rony Mia

“…The significance of this research lies in its contribution to sustainable textile processing by comparing the effectiveness of natural and synthetic dyes using an innovative heating method. MW treatment of up to 2–10 min was used to stimulate the dye solution and fabric, with dyeing variables were selected using statistical modelling. …”
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ONLINE and multi-objective trajectory planner for robotic systems by Habib Mohamad, Sadjaad Ozgoli

“…A novel trajectory planner for point-to-point movements has been developed to enable rapid and smooth motion by integrating the advantages of minimum acceleration and minimum jerk trajectories. This innovative approach, tailored for a diverse range of robotic systems, generates a multi-objective and optimized trajectory as a single segment for seamless online implementation. …”
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Reimagining Counterstruggle as a Comprehensive Theoretical Framework for Policy Design and Implementation: Dimensions and Factors of Struggle and Resistance by Sergei Khatunov

“…This stimulates the development of innovative solutions that are actively used by political actors to analyze the economic, social, political situation in countries and regions with transitional political and economic systems, as well as to prepare public opinion for making important political decisions. …”
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High-Order Engineering Fastest Controller and Its Application in Thermal Power Units by Shangyao Shi, Jun Li, Yijia Huo, Ruiqi Li, Pengyun Chen

“…The incumbent PID control schema is found wanting in this regard, precipitating the imperative for an innovative process control technology to supplant the conventional PID regimen. …”
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Controversial Issues of Hydrocarbon Field Formation and the Role of Geomagnetic Fields by Andrey A. Ponomarev, Marsel A. Kadyrov, Yuri V. Vaganov, Valeria A. Cheymetova, Vadim M. Aleksandrov, Aleksandr V. Morev

“…Elaborating this research area has excellent prospects for developing new criteria for hydrocarbon prospecting and devising innovative methods to enhance the oil recovery for shale oil production.…”
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Biodegradable Packaging Made from Proteins by Samar Sahraee, Jafar Milani

“…Researchers are exploring innovative methods to enhance the film-forming properties of proteins, improve their mechanical strength, and optimize their gas barrier performance. …”
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Grossschutzgebiete in den slowakischen Karpaten als Kompensation urbaner Verdichtung by Heino Meessen, Juraj Švajda, Thomas Kohler, Vladimíra Fabriciusová, Dobromil Galvánek, Miroslav Buraľ, Marcela Káčerová, Ján Kadlečík

“…A joint Slovak–Swiss financing mechanism enabled Slovak project partners to implement small innovative projects proposed by local stakeholders – so-called Seed Money Actions (SMAs). …”
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RenalSegNet: automated segmentation of renal tumor, veins, and arteries in contrast-enhanced CT scans by Rashid Khan, Chao Chen, Asim Zaman, Jiayi Wu, Haixing Mai, Liyilei Su, Yan Kang, Bingding Huang

“…RenalSegNet has an innovative encoder-decoder architecture, including the FlexEncoder Block for efficient multivariate feature extraction and the MedSegPath mechanism for advanced feature distribution and fusion. …”
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Recent Progress in Enzyme Immobilization to Metal–Organic Frameworks to Enhance the CO₂ Conversion Efficiency by Yunhan Cao, Pengyan Yang, Rui Zhao, Fenghuan Wang

“…The aim of this review is to present innovative ideas for future research and to highlight the potential applications of enzyme@MOFs in achieving efficient CO₂ conversion.…”
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Unlocking biochar impacts on abiotic stress dynamics: a systematic review of soil quality and crop improvement by Periyasamy Rathinapriya, Theivanayagam Maharajan, Ravi Jothi, Mayakrishnan Prabakaran, Mayakrishnan Prabakaran, In-Bog Lee, Pyoung-Ho Yi, Seung Tak Jeong

“…Global agricultural challenges, especially soil degradation caused by abiotic stresses, significantly reduce crop productivity and require innovative solutions. Biochar (BC), a biodegradable product derived from agricultural and forestry residues, has been proven to significantly enhance soil quality. …”
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Global research hotspots and trends in DNA vaccine research: A bibliometric and visualization study from 2014 to 2024 by Juan Zhang, Haiguo Zhang, Cuicui Yao, Lihua Gu, Shasha Dong, Yamei Wu, Lele Miao

“…Concurrently, the burst citation analysis identified emerging themes, including the development of DNA vaccines for COVID-19, Ebola, and MERS-CoV, as well as innovations in antigen design and delivery technologies. …”
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