HDAC6 inhibitor-loaded brain-targeted nanocarrier-mediated neuroprotection in methamphetamine-driven Parkinson's disease by Khang-Yen Pham, Shristi Khanal, Ganesh Bohara, Nikesh Rimal, Sang-Hoon Song, Thoa Thi Kim Nguyen, In-Sun Hong, Jinkyung Cho, Jong-Sun Kang, Sooyeun Lee, Dong-Young Choi, Simmyung Yook

“…These findings underscore the potential of PLGA@CAY@Lf NPs in treating Meth-induced PD and suggest that an innovative HDAC6-inhibitor-based strategy can be used to treat PD.…”
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A Theoretical Study on the Efficacy and Mechanism of Combined YAP-1 and PARP-1 Inhibitors in the Treatment of Glioblastoma Multiforme Using Peruvian Maca <i>Lepidium meyenii</i> by Albert Gabriel Turpo-Peqqueña, Sebastian Luna-Prado, Renato Javier Valencia-Arce, Fabio Leonardo Del-Carpio-Carrazco, Badhin Gómez

“…In conclusion, natural compounds from <i>Lepidium meyenii</i> (Peruvian Maca) offer a potentially innovative approach to improve GBM treatment, complementing existing therapies with their inhibitory action on PARP-1 and YAP-1.…”
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Artificial Intelligence’s (AI’s) Implications for Strategic Communication by Pay Shabangu

“… Organisations in Africa have integrated Artificial Intelligence’s (AI) innovations, such as data driven technologies and automation, into their operations. …”
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Decision support system for waste management: fuzzy group AHP-CoCoSo by Morteza Yazdani, Chenchui Ye, Mayssam Tarighi Shaayesteh, Pascale Zaraté

“…In order to rigorously and scientifically address collective waste management issues, this paper engages ten experts to score and evaluate criteria for waste management and alternative site locations. Innovatively integrating Fuzzy methodology with AHP-CoCoSo, the authors optimize decision-makers' preference inputs. …”
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Targeting BCMA in multiple myeloma: designs, challenges, and future directions by Yi Hu, Yuetao Xie, Xiaodong Wang, Lufeng Yang, He Geng, Zugang Yi, Yao Zhang, Lin Ma, Fang Chen

“…Moreover, the review spotlights cutting-edge developments, including dual-targeting CAR T strategies, advancements in CAR T cell manufacturing, and innovative allogeneic CAR T approaches utilizing healthy donor cells. …”
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EduDCM: A Novel Framework for Automatic Educational Dialogue Classification Dataset Construction via Distant Supervision and Large Language Models by Changyong Qi, Longwei Zheng, Yuang Wei, Haoxin Xu, Peiji Chen, Xiaoqing Gu

“…This article presents the EduDCM framework for the first time, offering an original approach to addressing these challenges. EduDCM innovatively integrates distant supervision with the capabilities of Large Language Models (LLMs) to automate the construction of high-quality educational dialogue classification datasets. …”
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Trends in research on novel antidepressant treatments by Agnieszka Zelek-Molik, Ewa Litwa

“…These models remain indispensable for understanding the physiological effects of newly developed compounds, thereby guiding the creation of innovative treatments.…”
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Between financial, environmental and health concerns: the role of risk perceptions in modeling efuel acceptance by Katrin Arning, Julia Offermann, Linda Engelmann, Regina Gimpel, Martina Ziefle

“…The transition towards sustainable and defossilized mobility systems relies on public perception and acceptance of innovations like efuels. Understanding the role of risk perceptions and their different dimensions in shaping public acceptance is therefore critical for facilitating the introduction of efuels into mobility systems. …”
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Quantitative estimation of drugs for erectile dysfunction and benign prostatic hyperplasia by high performance liquid chromatography: a review by Shalaka G. Gaonkar, Basavaraj M Dinnimath

“…By emphasizing the importance of HPLC in maintaining high analytical standards for ED and BPH drug analysis, this review serves as a valuable resource for researchers, clinicians, and pharmaceutical companies, ultimately aiming to enhance drug management and improve patient outcomes through better analytical practices and innovative approaches. …”
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Utility of complexity analysis in electroencephalography and electromyography for automated classification of sleep-wake states in mice by Naoki Furutani, Yuki C. Saito, Yasutaka Niwa, Yu Katsuyama, Yuta Nariya, Mitsuru Kikuchi, Tetsuya Takahashi, Takeshi Sakurai

“…Abstract We explore an innovative approach to sleep stage analysis by incorporating complexity features into sleep scoring methods for mice. …”
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Femtosecond Laser‐Induced Recrystallized Nanotexturing for Identity Document Security With Physical Unclonable Functions by Panpan Niu, Jiao Geng, Qilin Jiang, Yangyundou Wang, Jianxin Sang, Zhenghong Wang, Liping Shi

“…As a promising candidate, optical physical unclonable functions (PUFs) offer a robust defense mechanism against counterfeits. Despite the innovations in chemically synthesized PUFs, challenges persist, including harmful chemical treatments, low yields, and incompatibility of reaction conditions with the ID document materials. …”
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Application of Nighttime Light Data Simulation Based on Multi-Indicator System and Machine Learning Model in Predicting Potentially Suitable Economic Development Areas: A Case Stud... by Guangpeng Zhang, Li Zhang, Yiyang Chen, Meng Chen, Jingjing Tian, Yin Wu

“…To address these challenges, this study innovatively combines nighttime light remote sensing data to quantify urban economic development intensity and integrates socioeconomic and natural environment indicators based on previous research. …”
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Phosphodiesterase 4 inhibition as a novel treatment for stroke by Jiahong Zhong, Xihui Yu, Zhuomiao Lin

“…Therefore, the comprehensive investigation of phosphodiesterase 4 as an innovative pharmacological target for stroke injury provides valuable insights into the development of therapeutic interventions in stroke treatment. …”
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A Review of the Book “The Paleolithic Settlement of Asia” by Seyyed Milad Hashemi

“…The book comprises some important and rather innovative ideas about the subject which the author had been developing during his academic life; for instance, among them are the idea of the presence of an extensive grassland belt stretching from northeast Africa to east Asia during Early Pleistocene, which facilitated the dispersal of hominins out of Africa (Out of Africa I). …”
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Big Data Analysis Using Apache Spark MLlib and Hadoop HDFS with Scala and Java by Hoger Khayrolla Omar, Alaa Khalil Jumaa

“…Apache Spark is another tool that developed and established to be the real model for analyzing big data with its innovative processing framework inside the memory and high-level programming libraries for machine learning, efficient data treating and etc. …”
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How to Turn Trust into Non-material Asset of Higher Education by G. Zborovsky, P. Ambarova

“…Distrust destroys creative and innovative potential of educational communities. Another important function of trust in education is development of partnership and social networks between educational organizations, governing bodies, stakeholders, and parents. …”
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Pharmalens Augmented Reality Application For The Dangers of Illegal Drugs by A. Muh. Nurul Akbar, Imran Firman

“…By fostering greater public awareness and vigilance, this innovative approach contributes to the prevention of illegal drug misuse and supports broader health and safety objectives.…”
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Beyond immortality: Epstein–Barr virus and the intricate dance of programmed cell death in cancer development by Arezoo Esmaeili, Prankur Awasthi, Samira Tabaee

“…Furthermore, the insights gleaned from this review could catalyze the design of vaccines aimed at preventing EBV infection or curtailing its oncogenic impact. Innovatively, the review synthesizes recent discoveries on the multifaceted roles of non-coding RNAs and cellular signaling pathways in modulating cell death within the context of EBV infection. …”
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Role of Nanotechnology in Ischemic Stroke: Advancements in Targeted Therapies and Diagnostics for Enhanced Clinical Outcomes by Virendra Kumar Yadav, Rachna Gupta, Abdullah A. Assiri, Jalal Uddin, Azfar A. Ishaqui, Pankaj Kumar, Khalid M. Orayj, Shazia Tahira, Ashish Patel, Nisha Choudhary

“…Nanotechnology has played an immense role in managing strokes, and recently, it has emerged as a transformative solution offering innovative diagnostic tools and therapeutic strategies. …”
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Effects of ultrasonic rotating extrusion assisted wire arc additive manufacturing on the microstructure and mechanical properties of 5356 aluminum alloy by Rongtao Zhu, Liang Zhang, Longhan Duan, Zhaofeng Liang, Chuang Li, Bo Yuan, Peng Du, Zhiwen Xie, Yaping Zhang

“…In this investigation, an innovative approach termed Ultrasonic-Rotating Extrusion-Wire Arc Additive Manufacturing (U-RE-WAAM) was proposed, which integrates the synergistic effects of ultrasonic and mechanical force fields into the WAAM process. …”
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