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    Innate Immunity and Neuroinflammation by Abhishek Shastri, Domenico Marco Bonifati, Uday Kishore

    Published 2013-01-01
    “…Here, we discuss how innate immune components can also contribute to neuroinflammation and neurodegeneration.…”
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    Article
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    Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells by Jonathan Kevin Sia, Maria Georgieva, Jyothi Rengarajan

    Published 2015-01-01
    “…TB is caused by the human pathogen, Mycobacterium tuberculosis (Mtb), which infects primarily innate immune cells patrolling the lung. Innate immune cells serve as barometers of the immune response against Mtb infection by determining the inflammatory milieu in the lungs and promoting the generation of adaptive immune responses. …”
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    Article
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    Innate Immune Cells in Liver Inflammation by Evaggelia Liaskou, Daisy V. Wilson, Ye H. Oo

    Published 2012-01-01
    “…Innate immune system is the first line of defence against invading pathogens that is critical for the overall survival of the host. …”
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    Innate Immune Recognition of Mycobacterium tuberculosis by Johanneke Kleinnijenhuis, Marije Oosting, Leo A. B. Joosten, Mihai G. Netea, Reinout Van Crevel

    Published 2011-01-01
    “…Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem, with 10 million new cases diagnosed each year. Innate immunity plays an important role in the host defense against M. tuberculosis, and the first step in this process is recognition of MTB by cells of the innate immune system. …”
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    Article
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    The Role of TOX in the Development of Innate Lymphoid Cells by Corey R. Seehus, Jonathan Kaye

    Published 2015-01-01
    “…Recently, we have identified a broader role for TOX in the innate immune system, demonstrating that this nuclear protein is required for generation of bone marrow progenitors that have potential to give rise to all innate lymphoid cells. …”
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    The Role of Hyaluronan in Innate Defense Responses of the Intestine by Carol A. de la Motte, Sean P. Kessler

    Published 2015-01-01
    “…Here we discuss what is known about hyaluronan distribution during homeostasis and inflammatory diseases of the gut and discuss ways in which this glycosaminoglycan can participate in regulating innate host defense mechanisms. These natural responses include mechanisms promoting rapid leukocyte recruitment after bacterial challenge/colon tissue damage as well as promoting epithelial defense mechanisms in the intestine.…”
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    Article
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    Innate Immune Memory: The Latest Frontier of Adjuvanticity by Elfi Töpfer, Diana Boraschi, Paola Italiani

    Published 2015-01-01
    “…Epigenetic modifications seem to play a key role in the induction of this “innate memory.” These findings are revolutionising our knowledge of the immune system, introducing the concept of memory also for mammalian innate immunity. …”
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    Osteopontin Bridging Innate and Adaptive Immunity in Autoimmune Diseases by Nausicaa Clemente, Davide Raineri, Giuseppe Cappellano, Elena Boggio, Francesco Favero, Maria Felicia Soluri, Chiara Dianzani, Cristoforo Comi, Umberto Dianzani, Annalisa Chiocchetti

    Published 2016-01-01
    “…This review describes the OPN structure, isoforms, and functions and its role in regulating the crosstalk between innate and adaptive immunity in autoimmune diseases.…”
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    Emerging Roles of TRIM56 in Antiviral Innate Immunity by Dang Wang, Kui Li

    Published 2025-01-01
    “…While the physiological role(s) of TRIM56 remains unclear, emerging evidence suggests this protein participates in host innate defense mechanisms that guard against viral infections. …”
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    Stress Hyperglycemia, Insulin Treatment, and Innate Immune Cells by Fangming Xiu, Mile Stanojcic, Li Diao, Marc G. Jeschke

    Published 2014-01-01
    “…This review explored the interaction between the innate immune system and trauma-induced hypermetabolism, while providing greater insight into unraveling the relationship between innate immune cells and hyperglycemia. …”
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    Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response by Norma Y. Hernández-Pedro, Guillermo Espinosa-Ramirez, Verónica Pérez de la Cruz, Benjamín Pineda, Julio Sotelo

    Published 2013-01-01
    “…In the present review, we focus on the role of the innate immune system, the first line of defense of the organism, as promoter and mediator of cross reactions that generate molecular mimicry triggering the inflammatory response through an adaptive cytotoxic response in MS.…”
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    Transcriptional Regulatory Network for the Development of Innate Lymphoid Cells by Chao Zhong, Jinfang Zhu

    Published 2015-01-01
    “…Recent studies on innate lymphoid cells (ILCs) have expanded our knowledge about the innate arm of the immune system. …”
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