Cell fusion as a driver of metastasis: re-evaluating an old hypothesis in the age of cancer heterogeneity by Eduardo López-Collazo, Eduardo López-Collazo, Eduardo López-Collazo, Eduardo López-Collazo, Laura Hurtado-Navarro, Laura Hurtado-Navarro

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Utilizing Cytokines to Function-Enable Human NK Cells for the Immunotherapy of Cancer by Rizwan Romee, Jeffrey W. Leong, Todd A. Fehniger

“…Natural killer (NK) cells are innate lymphoid cells important for host defense against pathogens and mediate antitumor immunity. …”
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The Role of Mannose-Binding Lectin in Severe Sepsis and Septic Shock by Gennaro De Pascale, Salvatore Lucio Cutuli, Mariano Alberto Pennisi, Massimo Antonelli

“…Particularly when adaptive immune system is compromised or immature, innate immunity plays a key role in the immediate defense against invasive pathogens. …”
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Leptospira and Inflammation by C. F. Gonçalves-de-Albuquerque, P. Burth, A. R. Silva, M. Younes-Ibrahim, H. C. Castro-Faria-Neto, M. V. Castro-Faria

“…We propose that in addition to TLRs, Na/K-ATPase may play a role in the innate response to leptospirosis infection.…”
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Effects of Invariant NKT Cells on Parasite Infections and Hygiene Hypothesis by Jun-Qi Yang, Yonghua Zhou, Ram Raj Singh

“…Invariant natural killer T (iNKT) cells are unique subset of innate-like T cells recognizing glycolipids. iNKT cells can rapidly produce copious amounts of cytokines upon antigen stimulation and exert potent immunomodulatory activities for a wide variety of immune responses and diseases. …”
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Evidence of genetic determination of annual movement strategies in medium-sized raptors by Ivan Literák, Claudia Maria Kyseláková, Marek Dostál, Caka Karlsson, Jan Škrábal, Mykola Skyrpan, Ervín Hrtan, Lászlo Haraszthy, Rainer Raab

“…Abstract Most species of migrating birds use a combination of innate vector-based orientation programs and social information to facilitate accurate navigation during their life. …”
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IL-7 is a Key Driver Cytokine in Spondyloarthritis? by Rafaela Silva Guimarães Gonçalves, Angela Luzia Branco Pinto Duarte

“…IL-7 is a cytokine whose ability to stimulate IL-17 production in both innate and adaptive immunity cells has made it a promising target not only for a better understanding of the disease as well as an important potential therapeutic target in patients with SpA.…”
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Anti-Inflammatory and Antimicrobial Actions of Vitamin D in Combating TB/HIV by Anna K. Coussens, Adrian R. Martineau, Robert J. Wilkinson

“…Moreover, maintaining vitamin D sufficiency prior to MTB infection enhances the innate antimicrobial response to T cell-mediated interferon-γ. …”
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Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos. by Xi Li, Guanghua Xiong, Manni Luo, Siwan Mao, Ruiying Zhang, Ziwei Meng, Juan Li, Xinjun Liao

“…Peptidoglycan recognition proteins (PGRPs) are the evolutionarily highly conserved class of pattern recognition receptors, however, their functions on the innate immune system and neuro-inflammatory response in aquatic organism are still poorly understood. …”
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Self-Centered Function of Adaptive Immunity in Regulation of Immune Responses and in Tolerance by Silvana Balzar

“…Although mother-fetus interactions at that point become indirect systemic compartment-level communications, their interactions throughout gestation remain within the innate realm of molecular-level adaptations.…”
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Escherichia coli combination with PD-1 blockade synergistically enhances immunotherapy in glioblastoma multiforme by regulating the immune cells by Guochen Li, Haiyan Yang, Tengfei Ke, Na Tan, Xiaolan Du, Xirui Duan, Xinyan Zhou, Guangrong Zheng, Chengde Liao

“…ELISA kits were used to detect innate immune cytokines. Flow cytometry and immunofluorescence staining were used to investigate T cells. …”
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Psychological Stress and the Cutaneous Immune Response: Roles of the HPA Axis and the Sympathetic Nervous System in Atopic Dermatitis and Psoriasis by Jessica M. F. Hall, desAnges Cruser, Alan Podawiltz, Diana I. Mummert, Harlan Jones, Mark E. Mummert

“…A number of investigations have indicated that the skin is especially sensitive to psychological stress, and experimental evidence shows that the cutaneous innate and adaptive immune systems are affected by stressors. …”
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Secretory Leukocyte Protease Inhibitor Is an Inducible Antimicrobial Peptide Expressed in Staphylococcus aureus Endophthalmitis by Victor E. Reviglio, Ruben H. Sambuelli, Alejandra Olmedo, Micaela Falco, Jose Echenique, Terrence P. O'Brien, Irene C. Kuo

“…To describe the presence of secretory leukocyte protease inhibitor (SLPI), a cationic peptide with antimicrobial and antiprotease activity, in the innate ocular immune reaction in a rat model of Staphylococcus aureus endophthalmitis. …”
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Connexin-Based Therapeutics and Tissue Engineering Approaches to the Amelioration of Chronic Pancreatitis and Type I Diabetes: Construction and Characterization of a Novel Prevascu... by J. Matthew Rhett, Hongjun Wang, Heather Bainbridge, Lili Song, Michael J. Yost

“…A major obstacle has been low islet cell survival due largely to the innate inflammatory response. Connexin43 (Cx43) channels play a key role in early inflammation and have proven to be viable therapeutic targets. …”
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OMP38 of Carbapenem‐Resistant Acinetobacter Baumannii‐Mediated mtDNA Release Activates the cGAS‐STING Signaling to Induce Inflammatory Response by Yang Yang, Yuanyuan Zeng, Jianjie Zhu, Jianjun Li, Lei Gu, Lin Wei, Zeyi Liu, Jian‐an Huang

“…However, the role of the innate immune response in CRAB infection is poorly understood. …”
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Differences in immune cells and gene expression in human milk by parity on integrated scRNA sequencing by Dae Yong Yi, Hong-Jai Park, Min Sun Shin, Hyoungsu Kim, Sang Jin Lee, Insoo Kang

“…Conclusion Our results support the parity-dependent differences in gene expression between innate and adaptive immune cells.…”
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Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma by Christina Draijer, Patricia Robbe, Carian E. Boorsma, Machteld N. Hylkema, Barbro N. Melgert

“…In asthma, an important role for innate immunity is increasingly being recognized. …”
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The Role of T Cells and Macrophages in Asthma Pathogenesis: A New Perspective on Mutual Crosstalk by Xueyi Zhu, Jie Cui, La Yi, Jingjing Qin, Wuniqiemu Tulake, Fangzhou Teng, Weifeng Tang, Ying Wei, Jingcheng Dong

“…Asthma is associated with innate and adaptive immunity mediated by immune cells. …”
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Small Non-coding Transfer RNA-Derived RNA Fragments (tRFs): Their Biogenesis, Function and Implication in Human Diseases by Yu Fu, Inhan Lee, Yong Sun Lee, Xiaoyong Bao

“…They play regulatory roles in several biological contexts such as cancer, innate immunity, stress responses, and neurological disorders. …”
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Extracellular Cold-Inducible RNA-Binding Protein and Hemorrhagic Shock: Mechanisms and Therapeutics by Naureen Rashid, Zhijian Hu, Asha Jacob, Ping Wang

“…Hemorrhagic shock is a type of hypovolemic shock and a significant cause of trauma-related death worldwide. The innate immune system has been implicated as a key mediator in developing severe complications after shock. …”
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