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  1. 1

    Innate Immunity and Neuroinflammation by Abhishek Shastri, Domenico Marco Bonifati, Uday Kishore

    Published 2013-01-01
    “…Here, we discuss how innate immune components can also contribute to neuroinflammation and neurodegeneration.…”
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    Article
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    Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells by Jonathan Kevin Sia, Maria Georgieva, Jyothi Rengarajan

    Published 2015-01-01
    “…TB is caused by the human pathogen, Mycobacterium tuberculosis (Mtb), which infects primarily innate immune cells patrolling the lung. Innate immune cells serve as barometers of the immune response against Mtb infection by determining the inflammatory milieu in the lungs and promoting the generation of adaptive immune responses. …”
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    Article
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    Innate Immune Cells in Liver Inflammation by Evaggelia Liaskou, Daisy V. Wilson, Ye H. Oo

    Published 2012-01-01
    “…Innate immune system is the first line of defence against invading pathogens that is critical for the overall survival of the host. …”
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    Article
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    Innate Immune Recognition of Mycobacterium tuberculosis by Johanneke Kleinnijenhuis, Marije Oosting, Leo A. B. Joosten, Mihai G. Netea, Reinout Van Crevel

    Published 2011-01-01
    “…Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a major health problem, with 10 million new cases diagnosed each year. Innate immunity plays an important role in the host defense against M. tuberculosis, and the first step in this process is recognition of MTB by cells of the innate immune system. …”
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    Article
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    Innate Immune Memory: The Latest Frontier of Adjuvanticity by Elfi Töpfer, Diana Boraschi, Paola Italiani

    Published 2015-01-01
    “…These findings are revolutionising our knowledge of the immune system, introducing the concept of memory also for mammalian innate immunity. Thus, vaccines are likely to nonspecifically affect the overall immunological status of individuals in a clinically relevant manner. …”
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    Article
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    Emerging Roles of TRIM56 in Antiviral Innate Immunity by Dang Wang, Kui Li

    Published 2025-01-01
    “…Further studies understanding the complexity of TRIM56 involvement in innate immunity will add to critical knowledge that could be leveraged for developing antiviral therapeutics.…”
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    Stress Hyperglycemia, Insulin Treatment, and Innate Immune Cells by Fangming Xiu, Mile Stanojcic, Li Diao, Marc G. Jeschke

    Published 2014-01-01
    “…A comprehensive review of published literatures on the effects of hyperglycemia and insulin on innate immunity in critical illness was conducted. This review explored the interaction between the innate immune system and trauma-induced hypermetabolism, while providing greater insight into unraveling the relationship between innate immune cells and hyperglycemia. …”
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    Initial Immunopathogenesis of Multiple Sclerosis: Innate Immune Response by Norma Y. Hernández-Pedro, Guillermo Espinosa-Ramirez, Verónica Pérez de la Cruz, Benjamín Pineda, Julio Sotelo

    Published 2013-01-01
    “…In the present review, we focus on the role of the innate immune system, the first line of defense of the organism, as promoter and mediator of cross reactions that generate molecular mimicry triggering the inflammatory response through an adaptive cytotoxic response in MS.…”
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    Sublethal Heavy Metal Stress Stimulates Innate Immunity in Tomato by Nilanjan Chakraborty, Swarnendu Chandra, Krishnendu Acharya

    Published 2015-01-01
    “…The result suggested that the sublethal dose of heavy metal can induce an array of plant defense responses that lead to the improvement of innate immunity in plants.…”
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    PPARγ and the Innate Immune System Mediate the Resolution of Inflammation by Amanda Croasdell, Parker F. Duffney, Nina Kim, Shannon H. Lacy, Patricia J. Sime, Richard P. Phipps

    Published 2015-01-01
    “…The resolution of inflammation is an active and dynamic process, mediated in large part by the innate immune system. Resolution represents not only an increase in anti-inflammatory actions, but also a paradigm shift in immune cell function to restore homeostasis. …”
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    Article
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    An Overview of Pathogen Recognition Receptors for Innate Immunity in Dental Pulp by Ji-Hyun Jang, Hee Woong Shin, Jung Min Lee, Hyeon-Woo Lee, Eun-Cheol Kim, Sang Hyuk Park

    Published 2015-01-01
    “…The activation of PRRs is crucial for the initiation of innate immunity, which plays a key role in first-line defense until more specific adaptive immunity is developed. …”
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    Article
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    Pulmonary Innate Immune Response and Melatonin Receptors in the Perinatal Stress by Janaínna Grazielle Pacheco Olegário, Marcos Vinícius Silva, Juliana Reis Machado, Laura Penna Rocha, Marlene Antônia Reis, Camila Souza de Oliveira Guimarães, Rosana Rosa Miranda Corrêa

    Published 2013-01-01
    “…To analyze the cytokines of the innate immune pulmonary response and the capacity for local response to melatonin according to the perinatal stress. …”
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    Article
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    Role of Microbiota and Innate Immunity in Recurrent Clostridium difficile Infection by Stefano Bibbò, Loris Riccardo Lopetuso, Gianluca Ianiro, Teresa Di Rienzo, Antonio Gasbarrini, Giovanni Cammarota

    Published 2014-01-01
    “…Recent observations suggest that the alteration of the intestinal microbiota and impaired innate immunity may play a leading role in the development of recurrent infection. …”
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    Article
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    The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines by Stefan Landgraeber, Marcus Jäger, Joshua J. Jacobs, Nadim James Hallab

    Published 2014-01-01
    “…This inflammatory disease state is caused by implant debris acting, primarily, on innate immune cells, that is, macrophages. This slow progressive pathological bone loss or “aseptic loosening” is a potentially life-threatening condition due to the serious complications in older people (>75 yrs) of total joint replacement revision surgery. …”
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    Article
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