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141
Interferon-Stimulated Genes and Immune Metabolites as Broad-Spectrum Biomarkers for Viral Infections
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142
3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists
Published 2023-01-01“…Toll-like receptor 7 (TLR7) is an attractive target for developing immune modulators to enhance innate immunity against ssRNA virus infections, including hepatitis C and COVID-19. …”
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Analysis of Reproductive Strategies and Immunological Interactions in <i>Batrachochytrium dendrobatidis</i>-Resistant Japanese Tree Frogs
Published 2025-01-01“…Additionally, this analysis indicated that innate immunity was positively related to <i>Bd</i> infection intensities, indicating the activation of immunity upon infection. …”
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145
Normal Human Gingival Epithelial Cells Sense C. parapsilosis by Toll-Like Receptors and Module Its Pathogenesis through Antimicrobial Peptides and Proinflammatory Cytokines
Published 2010-01-01“…Overall results provide additional evidence of the involvement of epithelial cells in the innate immunity against C. parapsilosis infections.…”
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146
A c-type lectin HcLec1 with dual function of immunology and mineralization from the freshwater oyster (Hyriopsis cumingii Lea)
Published 2025-01-01“…Moreover, rHcLec1 promoted calcite crystal formation in saturated calcium carbonate solutions and altered crystal morphology.DiscussionThe HcLec1 gene plays a pivotal role in both innate immunity and biomineralization in the triangle sail mussel. …”
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147
MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi.
Published 2024-12-01“…However, the mcp5 mutant was able to establish infection and disseminate in NOD SCID Gamma (NSG) mice, which are deficient in both adaptive and most innate immune responses, suggesting that MCP5 plays an important role in evading host innate immunity. …”
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148
GITR-GITRL System, A Novel Player in Shock and Inflammation
Published 2007-01-01“…It is expressed in several cells and tissues, including T cells, natural killer cells, and, at lower levels, in cells of innate immunity. GITR is activated by its ligand, GITRL, mainly expressed on antigen presenting and endothelial cells. …”
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149
Budding of Enveloped Viruses: Interferon-Induced ISG15—Antivirus Mechanisms Targeting the Release Process
Published 2012-01-01“…As such, this represents a natural target for innate immunity mechanisms to interdict enveloped virus spread and recent advances in this field will be the subject of this paper.…”
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150
Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity
Published 2016-01-01“…It tries to link in vitro results to actual in vivo studies and outlines how hypoxia-mediated shaping of dendritic cells affects the activation of (innate) immunity.…”
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151
Role of Complement in Multiorgan Failure
Published 2012-01-01“…The underlying immune response is highly complex and involves activation of the complement system as a crucial entity of innate immunity. Uncontrolled activation of the complement system during sepsis and SIRS with in excessive generation of complement activation products contributes to an ensuing dysfunction of various organ systems. …”
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152
Identification of blood transcriptome modules associated with suicidal ideation in patients with major depressive disorder
Published 2025-01-01“…Additionally, three modules showed differences between MDD_nSI and HC: magenta (p = 0.009), brown (related to innate immunity and mitochondrial metabolism; p = 0.001), and turquoise (associated with energy metabolism and neurodegeneration; p = 0.005). …”
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153
Identification of signaling networks associated with lactate modulation of macrophages and dendritic cells
Published 2025-02-01“…This study identifies key biochemical pathways in innate immune cells that are impacted by lactate, which advances our understanding of the interplay between the tumor microenvironment and innate immunity.…”
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Roitt's essential immunology /
Published 2017Table of Contents: “…Innate immunity -- Specific acquired immunity -- Antibodies -- Membrane receptors for antigen -- Antigen-specific recognition -- Immunological methods and applications [JS2] -- The anatomy of the immune response -- Lymphocyte activation -- The production of effectors -- The regulation of the immune response -- Development and evolution of the immune response -- Adversarial strategies during infection -- Vaccines -- Immunodeficiency -- Allergy and other hypersensitivities -- Transplantation -- Tumor immunology -- Autoimmune diseases.…”
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156
Role of Neutrophils in Psoriasis
Published 2020-01-01“…The abnormalities of innate immunity play crucial roles in the pathogenesis of psoriasis. …”
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157
Mycobacterium bovis Bacillus Calmette-Guérin-Induced Macrophage Cytotoxicity against Bladder Cancer Cells
Published 2010-01-01“…Macrophages play pivotal roles in the host innate immunity and serve as a first line of defense in mycobacterial infection. …”
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158
The Toll of Vascular Insufficiency: Implications for the Management of Peripheral Arterial Disease
Published 2016-01-01“…While a body of literature continues to grow describing the role of danger signaling and innate immunity in cardiac biology, the role of these pathways in the ischemic myopathy associated with PAD has not been extensively studied. …”
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Dysbiosis in the Pathogenesis of Pediatric Inflammatory Bowel Diseases
Published 2012-01-01“…The fundamentals of IBD pathogenesis are considered a defective innate immunity and bacterial killing with overaggressive adaptive immune response. …”
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