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    Toll-Like Receptors and RIG-I-Like Receptors Play Important Roles in Resisting Flavivirus by Hong-Yan Guo, Xing-Cui Zhang, Ren-Yong Jia

    Published 2018-01-01
    “…In the present review, we provide a significant reference for further research on the function of innate immunity in resisting flavivirus.…”
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  12. 112

    The Role of Bacteria and Pattern Recognition Receptors in GvHD by E. Holler, K. Landfried, J. Meier, M. Hausmann, G. Rogler

    Published 2010-01-01
    “…With the detailed description of pathogen-associated molecular patterns and pathogen recognition receptors single nucleotide polymorphisms of TLRs and especially NOD2 have been identified as potential risk factors of GvHD and transplant related complications thus further supporting the crucial role of innate immunity in SCT, related complications. Gastrointestinal decontamination and neutralization of endotoxin have been used to interfere with this early axis of activation with some success but more specific approaches of modulation of innate immunity are needed for further improvement of clinical outcome.…”
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    3-(5-Hydroxyphenyl)-5-Phenyl-2-Pyrazolines as Toll-Like Receptor 7 Agonists by Ji Hwan Kim, Seunghyun Ahn, Dongsoo Koh, Young Han Lee, Yoongho Lim, Soon Young Shin

    Published 2023-01-01
    “…Toll-like receptor 7 (TLR7) is an attractive target for developing immune modulators to enhance innate immunity against ssRNA virus infections, including hepatitis C and COVID-19. …”
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  15. 115

    Analysis of Reproductive Strategies and Immunological Interactions in <i>Batrachochytrium dendrobatidis</i>-Resistant Japanese Tree Frogs by Ji-Eun Lee, Jun-Kyu Park, Yuno Do

    Published 2025-01-01
    “…Additionally, this analysis indicated that innate immunity was positively related to <i>Bd</i> infection intensities, indicating the activation of immunity upon infection. …”
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  16. 116

    Normal Human Gingival Epithelial Cells Sense C. parapsilosis by Toll-Like Receptors and Module Its Pathogenesis through Antimicrobial Peptides and Proinflammatory Cytokines by Raouf Bahri, Sèverine Curt, Dalila Saidane-Mosbahi, Mahmoud Rouabhia

    Published 2010-01-01
    “…Overall results provide additional evidence of the involvement of epithelial cells in the innate immunity against C. parapsilosis infections.…”
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  17. 117

    MCP5, a methyl-accepting chemotaxis protein regulated by both the Hk1-Rrp1 and Rrp2-RpoN-RpoS pathways, is required for the immune evasion of Borrelia burgdorferi. by Sajith Raghunandanan, Kai Zhang, Yan Zhang, Raj Priya, Ching Wooen Sze, Yongliang Lou, Michael J Lynch, Brian R Crane, Mark H Kaplan, Chunhao Li, X Frank Yang

    Published 2024-12-01
    “…However, the mcp5 mutant was able to establish infection and disseminate in NOD SCID Gamma (NSG) mice, which are deficient in both adaptive and most innate immune responses, suggesting that MCP5 plays an important role in evading host innate immunity. …”
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  18. 118

    GITR-GITRL System, A Novel Player in Shock and Inflammation by Ludovic Tibor Krausz, Rodolfo Bianchini, Simona Ronchetti, Katia Fettucciari, Giuseppe Nocentini, Carlo Riccardi

    Published 2007-01-01
    “…It is expressed in several cells and tissues, including T cells, natural killer cells, and, at lower levels, in cells of innate immunity. GITR is activated by its ligand, GITRL, mainly expressed on antigen presenting and endothelial cells. …”
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  19. 119

    Budding of Enveloped Viruses: Interferon-Induced ISG15—Antivirus Mechanisms Targeting the Release Process by Eun Joo Seo, Jonathan Leis

    Published 2012-01-01
    “…As such, this represents a natural target for innate immunity mechanisms to interdict enveloped virus spread and recent advances in this field will be the subject of this paper.…”
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  20. 120

    Dendritic Cells under Hypoxia: How Oxygen Shortage Affects the Linkage between Innate and Adaptive Immunity by Sandra Winning, Joachim Fandrey

    Published 2016-01-01
    “…It tries to link in vitro results to actual in vivo studies and outlines how hypoxia-mediated shaping of dendritic cells affects the activation of (innate) immunity.…”
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