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4941
Acute Myocardial Infarction of the Left Main Coronary Artery Presenting with Cardiogenic Shock and Pulmonary Edema during Noncardiac Surgery
Published 2021-01-01“…Early identification of the cause of hemodynamic instability during noncardiac surgery and invasive strategy are important for minimizing the myocardial injury and improving clinical outcomes in AMI of LMCA.…”
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4942
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction
Published 2025-01-01“…Histological examination, sperm concentration and motility analysis, Western blotting (WB), and reverse transcription quantitative PCR (RT-qPCR) were used to evaluate testicular injury. The therapeutic potential of NF-κB agonists was investigated in an IR-induced spermatogenesis disorder model. …”
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4943
Stem Cells from Human Exfoliated Deciduous Teeth Ameliorate Diabetic Nephropathy In Vivo and In Vitro by Inhibiting Advanced Glycation End Product-Activated Epithelial-Mesenchymal...
Published 2019-01-01“…At 8 weeks after administration, renal injury, including hyperglycemia, hyperlipidemia, increased urinary albumin excretion, ECM accumulation, and a fractional mesangial area, was dramatically attenuated. …”
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4944
Recurrent patellar dislocation: treatments and challenges
Published 2025-02-01“…Recurrent Patellar Dislocation (RPD) is a common knee sports injury, mainly affecting pediatric and adolescent populations, posing a significant challenge in orthopedic clinical practice. …”
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4945
Identification of glutamine as a potential therapeutic target in dry eye disease
Published 2025-01-01“…Clinical cases and rodent model showed elevated expression of glutaminase (GLS1), an upstream enzyme in glutamine metabolism, following dry eye injury. Mechanistic studies indicated that overexpression and inhibition of GLS1 counteracted and enhanced, respectively, the anti-inflammatory effects of combined therapy, underscoring GLS1’s pivotal role in regulating glutamine metabolism. …”
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4946
Ziziphus jujube promotes fertility and pregnancy outcomes in Rat model of uterine adhesions
Published 2025-01-01“…IntroductionThe therapeutic efficacy of oral administration of Ziziphus jujube in the context of uterine adhesion (UA) and its impact on pregnancy outcomes was investigated.MethodsIn a rat UA model, Z. jujube was evaluated for its ability to mitigate injury-induced uterine adhesion bands, uterine shortening, and enhance endometrial regeneration. …”
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4947
Single dose of recombinant baculovirus vaccine expressing sigma B and sigma C genes provides good protection against novel duck reovirus challenge in ducks
Published 2025-01-01“…Protective efficacy results revealed that, compared with the whole virus inactivated vaccine, a single dose of 160 ng σB or σC protein showed advantages in inducing serum antibodies, elevating weight, alleviating liver and spleen injury, restraining viral shedding and viral replication in ducklings. …”
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4948
Regeneration of Tracheal Tissue in Partial Defects Using Porcine Small Intestinal Submucosa
Published 2018-01-01“…Although tracheal SIS engraftment could not prevent stenosis in a rabbit model of tracheal injury, it produced some remarkable changes, efficiently facilitating neovascularization, reepithelialization, and neoformation of immature cartilage.…”
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4949
Naringenin Protects against Acute Pancreatitis in Two Experimental Models in Mice by NLRP3 and Nrf2/HO-1 Pathways
Published 2018-01-01“…In contrast, glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), total sulfhydryl (T-SH), and non-proteinsulthydryl (NP-SH) were markedly increased in both MAP and SAP after Nar treatment. The injury in pancreatic and pulmonary tissues was markedly improved as evidenced by the inhibited expression of myeloperoxidase, nod-like receptor protein 3, and interleukin 1 beta as well as the enhanced expression of nuclear factor erythroid 2-related factor 2/heme oxygenase-1 in pancreatic tissues. …”
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4950
Clinical and cost-effectiveness of Knee Arthroplasty versus Joint Distraction for Osteoarthritis (KARDS): protocol for a multicentre, phase III, randomised control trial
Published 2022-06-01“…The primary outcome measure is the Knee Injury and Osteoarthritis Outcomes Score (KOOS) pain domain score at 12 months post-operation. …”
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4951
New evidence on the nephrotoxicity of fine particulate matter: Potential toxic components from different emission sources
Published 2025-02-01“…PM2.5 water extracts from both sites induced inflammatory cytokine upregulation in the lungs and kidneys, and inflammatory cell infiltration, antioxidant activity downregulation, and elevated levels of kidney injury molecule 1 in the kidneys. Exposure to PM2.5 water extract increased the mRNA levels of tumor necrosis factor-α, interleukin-6, and nitrite production in RAW264.7 macrophages. …”
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4952
Machine learning-based identification and validation of amino acid metabolism related genes as novel biomarkers in chronic kidney disease
Published 2025-01-01“…All key genes correlated significantly with markers of kidney injury, such as eGFR and serum creatinine. The expression of ALDH18A1, CENPF were increased while CSAD, CTH and CYP27B1 were decreased in HK-2 cells cultured with indole sulfate. …”
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4953
Ambulance attendances involving personality disorder – investigation of crisis-driven re-attendances for mental health, alcohol and other drug, and suicide-related events
Published 2025-04-01“…Most presentations involved suicide attempts, suicidal ideation, non-suicidal self-injury, and drug and alcohol harms. Most attendances (87.9%) were transported to emergency departments. …”
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4954
Effect of Bee Resin on Blood Profiles of Infected Carassius auratus by Aeromonas hydrophila
Published 2007-07-01“… Bee resin is an organic matter that can be used as immunostimulant to induce cells and tissues regeneration for fast injury recovery. In order to determine the effect of bee resin on blood profile of goldfish, Carassius auratus that had been infected by Aeromonas hydrophila, the numbers of hemoglobin, hetmaocrite, erythrocyte and leukocyte, and leukocyte differentiation were observed. …”
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4955
The ameliorative effects of melatonin against BDE-47-induced hippocampal neuronal ferroptosis and cognitive dysfunction through Nrf2-Chaperone-mediated autophagy of ACSL4 degradati...
Published 2025-01-01“…Importantly, melatonin, CMA activator CA77.1, and ACSL4 inhibitor rosiglitazone (RSG) administration substantially attenuated neuronal/synaptic injury and cognitive deficits following BDE-47 exposure. …”
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4956
Surgical resection, radiotherapy and percutaneous thermal ablation for treatment of stage 1 non-small cell lung cancer: protocol for a systematic review and network meta-analysis
Published 2022-06-01“…The primary outcomes will include cancer-specific survival, lung disease-free survival, locoregional recurrence, death, toxicity and non-target organ injury. We will also search published and unpublished studies in trial registries and will review references of included studies for possible inclusion. …”
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4957
Two-stage revision anterior cruciate ligament reconstruction reduces failure risk but leads to lesser clinical outcomes than single-stage revision after primary anterior cruciate l...
Published 2025-01-01“…Revision intraoperative data, concomitant injuries, and complications were collected by chart review. …”
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4958
Manual of Clinical anesthesiology :
Published 2021Table of Contents: “…-- Hemodynamic collapse following a mainstem intubation -- Hypoxemia during tracheostomy -- Anesthetic depth and mask ventilation in the prone position -- Jet ventilation through a cookgas airway exchange catheter -- End of case evaluation and management of a patient post airway mass excision -- Possible recurrent laryngeal nerve injury -- Obstructive sleep apnea, and dead in bed -- Bilevel positive air pressure, decreased sensorium, aspiration and capnography -- Perioperative management of a patient previously treated with bleomycin undergoing thoracic surgery -- Intra-operative airway fire -- Obesity hypoventilation syndrome -- Circulation-related cases -- Hemorrhage during endovascular repair of thoracic aorta -- Pacemakers and automatic implantable cardioverter defibrillators -- Acute myocardial infarction during laparoscopic surgery -- Sickle cell and preeclampsia -- Dysrhythmias in a patient with Crohn's disease -- Hematologic disorders: hemophilia and disseminated intravascular coagulation -- Blood transfusion and the Jehovah's Witness patient -- Cardiac and pulmonary contusions -- Intraoperative coagulopathy -- Hypotension in chronic methamphetamine user -- Venous air embolism during arteriovenous malformation repair -- Cardiac tamponade -- Case of intraoperative new-onset atrial fibrillation -- Valvular disease -- Obstetrics-related cases -- Labor epidural with unrecognized dural puncture, causing high sensory block, hypotension, fetal bradycardia and post dural puncture headache -- Acute pulmonary dysfunction immediately after cesarean delivery under general anesthesia -- Jehovah's Witness with placenta previa and increta for cesarean hysterectomy -- A pregnant patient with mitral stenosis -- Unrecognized uterine hyperstimulation due to oxytocin and combined spinal-epidural analgesia -- Super morbidly obese patient for elective repeat cesarean section -- Probable amniotic fluid embolus -- Emergent cesarean section -- Pregnancy plus atrial septal defect vs Eisenmenger Syndrome -- Uterine abruption -- Pediatric-related cases -- Neonatal resuscitation following spontaneous vaginal delivery -- Anxious, coughing and bound to obstruct -- Special diseases/conditions/situations -- Hypothermia during laparoscopic nephrectomy -- Operating room management case scenarios -- Anaphylaxis reactions -- Autonomic dysreflexia -- Porphyrias -- Monitored anesthesia care: medical implications; and wrong-sided operations: legal implications -- Diabetic ketoacidosis in the urgent anesthesia setting -- Fever, altered mental status, and rigidity in the perioperative course -- Neuro/neuromuscular-related cases -- Emergent craniotomy for evacuation of epidural hematoma -- Hyperkalemia and residual neuromuscular blockade after kidney transplantation -- A defasciculating dose of nondepolarizing neuromuscular blocker -- Postoperative monocular vision loss -- Delayed emergence after aneurysm clipping -- Pain and regional anesthesia related cases -- Unintentional dural puncture in a patient with severe preeclampsia -- Complex regional pain syndrome -- Vascular absorption of local anesthetic producing systemic toxicity -- Inadvertent high spinal in parturient -- Outpatient surgery-related cases -- Plastic surgery in a surgeon's office -- Orthopedic surgery in an ambulatory surgicenter -- Eye surgery at an outpatient surgicenter -- Endoscopic sinus surgery at an outpatient sugicenter.…”
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4959
SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial
Published 2025-02-01“…The primary outcomes are the 3-month change in (1) severity of the worst knee pain experienced over the past week, measured using a Numerical Rating Scale, and (2) the function in sport and play subscale of the Knee Injury and Osteoarthritis Outcome Score for Children. …”
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4960
Abortion-related complications in Brazil: results from the World Health Organization Multi-country Survey on Abortion (MCS-A)
Published 2025-01-01“…Women with hemorrhage, infection or organs injury were invited to answer an interview about experience of care. …”
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