Dynamic balance control in healthy young women during stair descent: a plantar pressure-based study by Ruiqin Wang, Ruiqin Wang, Jinfeng Cao, Haoran Xu, Panjing Guo, Yumin Li, Yuyi Fan, Yunfei Gui, Leqi Li, Roger Adams, Jia Han, Jia Han, Jia Han, Jie Lyu, Jie Lyu

“…There was no significant difference in the kinematic parameters of plantar pressure during stair descent, regardless of whether the dominant foot or non-dominant foot was the leading foot.ConclusionThis study found that among young women, an increase in step height during descent significantly affected the plantar pressure and led to greater COP adjustment in the directions of ML and AP, increasing the risk of injury. At a step height of 5 cm, the first choice of the landing strategy for female subjects began to change from the hindfoot to the forefoot. …”
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Beetroot (Beta vulgaris L.) Extract Ameliorates Gentamicin-Induced Nephrotoxicity Associated Oxidative Stress, Inflammation, and Apoptosis in Rodent Model by Ali A. El Gamal, Mansour S. AlSaid, Mohammad Raish, Mohammed Al-Sohaibani, Shaza M. Al-Massarani, Ajaz Ahmad, Mohamed Hefnawy, Mohammed Al-Yahya, Omer A. Basoudan, Syed Rafatullah

“…BVEE treatment also ameliorated the extent of histologic injury and reduced inflammatory infiltration in renal tubules. …”
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Blood-brain barrier breakdown in brain ischemia: Insights from MRI perfusion imaging by Sarvin Sasannia, Richard Leigh, Pouya B. Bastani, Hyeong-Geol Shin, Peter van Zijl, Linda Knutsson, Paul Nyquist

“…Hence, understanding the mechanisms of BBB breakdown and white matter injury across various ischemic conditions is critical for developing effective interventions and improving patient outcomes. …”
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Noninvasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B or C by Contrast-Enhanced Magnetic Resonance Imaging by René Hako, Pavol Kristian, Peter Jarčuška, Ivana Haková, Ivana Hockicková, Ivan Schréter, Martin Janičko

“…The first group (n=19) was a control group of healthy individuals without liver injury and remaining 59 subjects were chronic hepatitis B and C patients who underwent liver biopsy. …”
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Adverse events of hepatic anti-fibrotic agents in phase 3 and above clinical trials: a descriptive analysis of the WHO-VigiAccess database by Yuwei Liu, Yuwei Liu, Xu Zhao, Xu Zhao, Xinrui Wang, Xinrui Wang, Qiang Zhou, Qiang Zhou

“…IntroductionLiver fibrosis is a pathological condition in response to chronic liver injuries. Currently, there is no Food and Drug Administration (FDA) approved pharmacotherapy for liver fibrosis. …”
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Bone Defect Repair Using a Bone Substitute Supported by Mesenchymal Stem Cells Derived from the Umbilical Cord by Michal Kosinski, Anna Figiel-Dabrowska, Wioletta Lech, Lukasz Wieprzowski, Ryszard Strzalkowski, Damian Strzemecki, Lukasz Cheda, Jacek Lenart, Krystyna Domanska-Janik, Anna Sarnowska

“…Bone defects or atrophy may arise as a consequence of injury, inflammation of various etiologies, and neoplastic or traumatic processes or as a result of surgical procedures. …”
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Exosome miR-199a-5p modulated vascular remodeling and inflammatory infiltration of Takayasu’s arteritis by Shuning Guo, Jiehan Li, Shurui Pang, Jing Li, Xinping Tian

“…Moreover, exosome miR-199a-5p and MMP2 derived from serum possess potential as future biomarkers for vascular injury.…”
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Robotic-assisted surgery and kinematic alignment in total knee arthroplasty (RASKAL study): a protocol of a national registry-nested, multicentre, 2×2 factorial randomised trial as... by Ian A Harris, Samuel J MacDessi, Aziz Bhimani, Darren B Chen, Ian Harris, Michelle Lorimer, David Parker, Tamara Hooper, Richard Boyle, Jonathan Mulford, Daniel Franks, Gregory C Wernecke, Durga Bastiras, Emma Heath, Anthony Leong, Brett Fristch, David Penn, George Kirsh, John Limbers, Julian Yu, Maurice Guzman, Peter McEwen

“…The primary outcome will be the between-group differences in postoperative change over 2 years in the mean Knee injury and Osteoarthritis Outcome Score (KOOS-12), comparing first, RAS to CAS as its control, and second, KA to MA as its control. …”
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Immunomodulatory Functions of Mesenchymal Stem Cells in Tissue Engineering by Haojiang Li, Shi Shen, Haitao Fu, Zhenyong Wang, Xu Li, Xiang Sui, Mei Yuan, Shuyun Liu, Guiqin Wang, Quanyi Guo

“…The inflammatory response to chronic injury affects tissue regeneration and has become an important factor influencing the prognosis of patients. …”
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Cancer therapy-related interstitial lung disease by Chengzhi Zhou, Haiyi Deng, Yilin Yang, Fei Wang, Xinqing Lin, Ming Liu, Xiaohong Xie, Tao Luan, Nanshan Zhong, Peifang Wei

“…With the increasing utilization of cancer therapy, the incidence of lung injury associated with these treatments continues to rise. …”
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Within- and between-day test–retest reliability of responses to rapid bilateral anterolateral magnetic phrenic nerve stimulation in healthy humans (ReStim) by Kyle G. P. J. M. Boyle, Andrea A. Beglinger, Heinrich Häusler, Anna Stahel, Esther I. Schwarz, Esther I. Schwarz, Christina M. Spengler, Christina M. Spengler

“…BackgroundMechanical ventilation can lead to lung injury and diaphragmatic dysfunction. Rapid bilateral anterolateral magnetic phrenic nerve stimulation (rBAMPS) may attenuate both of the aforementioned issues by inducing diaphragm activation. …”
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Inflammatory adhesion mediates myocardial segmental necroptosis induced by mixed lineage kinase domain-like protein in acute myocardial infarction by Lijiang Wei, Naifu Wan, Wentong Zhu, Chenchen Liu, Zeyu Chen, Wuwei Rong, Lujun Zhang, Meifeng Xie, Yueqi Qin, Ting Sun, Qing Jing, Ankang Lyu

“…Additionally, myocardial injury was significantly ameliorated in MLKLM−KO mice following AMI. …”
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Artemisinin supplementation in concentrated cottonseed protein basal diets enhances growth, antioxidant capacity, intestinal immunity and microbiota in hybrid grouper (Epinephelus... by Ling Pan, Qi Wang, Weikang Li, Xiaohui Dong, Shiwei Xie, Beiping Tan, Hongyu Liu, Yan Wang

“…In the artemisinin-treated groups, significant alterations in gene expression were observed, including a marked upregulation of interleukin-8, tumor necrosis factor-α, and toll-like receptor-2 (P < 0.05); however, the expression of tumor necrosis factor-β and toll-like receptor-1 was significantly downregulated (P < 0.05), suggesting that artemisinin may mitigate intestinal inflammatory injury. Artemisinin supplementation significantly enhanced the activities of SOD, GSH-Px, CAT, and T-AOC in the liver and hindgut (P < 0.05),while also reducing MDA levels, thereby demonstrating its protective effect against oxidative stress and its ability to strengthen antioxidant defense system. …”
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Duration of Disease and Long‐Term Outcomes in Patients With Difficult‐To‐Treat Recurrent Pericarditis: A Chronic Condition Treated With Nonsteroidal Anti‐Inflammatory Drugs, Colchi... by Elisa Ceriani, Francesco Agozzino, Silvia Berra, Antonio Gidaro, Paolo Bindi, Alberto Pavarani, Silvia Macchi, Letizia Vena, Francesco Moda, Ludovico Luca Sicignano, Celeste Ambra Murace, Laura Gerardino, Elena Verrecchia, Caterina Chiara De Carlini, Silvia Maestroni, Gabriella Marinaro, Emanuele Bizzi, Antonio Brucato, Massimo Imazio

“…Objective We aimed to investigate the remission rate and disease duration in idiopathic or post–cardiac injury pericarditis and risk factors for disease duration and anti–interleukin‐1 (IL‐1) agent discontinuation. …”
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Ginseng exhibits adaptogenic-like activity in mice exposed to hypoxic-anoxic stress through activation of antioxidant/BDNF protective mechanisms and inhibition of pro-inflammatory... by James Olukayode Oni, Divine Oluwaferanmi Oyenekan, Yetunde Olamide Olayemi, Osarugue Christabel Irabor, Precious Ogbuji, McCarthy Oritseweyinmi Tova, Paul Ademola Adeleke, Gbemisayo Adetomiwa Abbas, Solomon Umukoro

“…Introduction: Hypoxic-anoxic stress causes severe injury to the brain cells resulting in various neuropathological complications. …”
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Mapping outcomes for recovery of consciousness in studies from 1986 to 2020: a scoping review protocol by Monica Steiner, Elizabeth Burns, Trudy Mallinson, Joshua Rosenow, Jennifer Weaver, Alison Cogan, Parie Bhandari, Erica Jacobs, Ariana Pape, Chantal Nguyen, Ann Guernon, Tom Harrod, Theresa Bender Pape, Marilyn Pacheco, Catherine Burress Kestner, Kelsey Watters, Elizabeth Yost, Henk Eilander, Berno Overbeek, Sophie Leeds, Kelly Krese, Haylee Winden, Mary Philbin, Stefani Cleaver, Vanessa Silva, Konner Nelson, André Lindsey, Angela Hartman, Kristen Maisano, Erika Cooley, Jessica Rudin Portnoff, Bailey Widener, Sarah Hollingsworth, Coty Wardwell, Julianne Angel, Ladan Hakima, Jennifer Nebel, Bint-e Zainab Awan

“…Introduction Historically, heterogeneous outcome assessments have been used to measure recovery of consciousness in patients with disorders of consciousness (DoC) following traumatic brain injury (TBI), making it difficult to compare across studies. …”
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Adaptive Autophagy Offers Cardiorenal Protection in Rats with Acute Myocardial Infarction by Zhendong Feng, Han Xue Jiang, Huiyang Chen, Yu Ning Liu, Yahui Wang, Rui Bing Yang, Xueting Han, Chen Hui Xia, Ze Bing Zhu, Hongcai Shang, Aiming Wu, Wei Jing Liu

“…At weeks 2 and 4, the level of urinary kidney injury molecule 1 (uKIM1) of the model group was significantly higher than the sham group. …”
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The additional impact of metabolic syndrome on left ventricular deformation and myocardial energetic efficiency impairment in ischemia with nonobstructive coronary arteries patient... by Chen-Yan Min, Yue Gao, Yuan Li, Yi-Ning Jiang, Ying-Kun Guo, Hua-Yan Xu, Rong Xu, Xi Liu, Li-Ting Shen, Zhi-Gang Yang

“…MetS was found to be an independent factor of impaired MEEI and LV GLPS, the further decrease of MEEI and LV GLPS in INOCA patients caused by MetS might involve the synergistic injury mechanism. Early diagnosis and treatment of MetS in patients with INOCA are important.…”
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Distal Femur Type III Open Fractures: Functional Outcome Analysis by Arul R Bhagyaraj, Anand Ashok, Manisha J Kumar, Krupakaran Ganesan, Anand Kurian, Dan B Inja, Manasseh Nithyananth, Vinoo M Cherian, Jeremy Bliss

“…About 11% of patients had vascular injuries, all of whom underwent amputation. The high velocity of injury correlated with poor knee range of movements (<i>p</i>-value of 0.030). …”
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Restoring coronal pre-arthritic alignment in mobile-bearing unicompartmental knee arthroplasty: mid- to long-term outcomes by Yankun Jiang, Changquan Liu, Qidong Zhang, Guoyuan Sun, Ran Ding, Nianfei Zhang, Cheng Huang, Weiguo Wang, Wanshou Guo

“…Final follow-up occurred in September 2024, and outcome measures included the visual analogue scale (VAS) score, Hospital for Special Surgery (HSS) score, and Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales for daily living, sports, and survivorship. …”
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