Extracorporeal hyperoxygenation therapy (EHT) for CO poisoning: in vitro and in vivo feasibility of a full-scale batch system by Niklas B. Steuer, Hannah Lüken, Peter C. Schlanstein, Matthias F. Menne, Christiane Hoffmann, Cavan Lübke, Thomas Schmitz-Rode, Sebastian Victor Jansen, Ulrich Steinseifer, Rüdger Kopp

“…Abstract Carbon monoxide (CO) poisoning is one of the most common causes of injury and death from poisoning. The primary objective of therapy is to eliminate CO from the patient as quickly as possible to prevent acute and long-term effects. …”
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Astrocytic Acid-Sensing Ion Channel 1a Contributes to the Development of Epileptic Cognitive Impairment by Wen Li, Huimin Zhou, Xiaona Li, Gengyao Hu, Dong Wei

“…Reactive astrogliosis and acidosis, common features of epileptogenic lesions, express a high level of astrocytic acid-sensing ion channel-1a (ASIC1a), a proton-gated cation channel and key mediator of responses to neuronal injury. This study investigates the role of astrocytic ASIC1a in cognitive impairment following epilepsy. …”
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Falls and Fractures in the Elderly with Sinus Node Disease: The Impact of Pacemaker Implantation by Nazmi Krasniqi, Diana Segalada, Thomas F. Lüscher, Kurt Lippuner, Laurent Haegeli, Jan Steffel, Thomas Wolber, Corinna Brunckhorst, Johannes Holzmeister, David Hürlimann, Firat Duru

“…Similarly, the number of falls was reduced from 60 (48%) before pacemaker implantation to 22 (18%) thereafter (relative reduction 63%, P=0.035) and the number of falls with injury from 22 (18%) to 7 (6%), which corresponds to a relative reduction of 67%, P=0.013. …”
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Improved Outcome of Severe Acute Pancreatitis in the Intensive Care Unit by Polychronis Pavlidis, Siobhan Crichton, Joanna Lemmich Smith, David Morrison, Simon Atkinson, Duncan Wyncoll, Marlies Ostermann

“…Forty patients (80%) tolerated enteral nutrition, and 46% received antibiotics for non-SAP reasons. Acute kidney injury was significantly more common among hospital nonsurvivors compared to survivors (100% versus 42%, ). …”
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Perioperative hypothermia prevention: development of simple principles and practice recommendations using a multidisciplinary consensus-based approach by Fiona M Wood, Nicholas Ralph, Jed Duff, Judy Munday, David Sturgess, Mary-Anne Ramis

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Delayed Postoperative Ambulation Results in a Significant Increase in 90-Day Mortality in Surgically Treated Hip Fractures by Robert S. Wood DO, Maddie Vergun BS, Elizabeth Herrera MPH, Jacqueline Krumrey MD

“…Patients over age 60, who underwent surgical treatment of a femoral neck or intertrochanteric fracture after receiving a preoperative block and were able to ambulate prior to their injury included. Cases and controls were matched based upon patient demographics including comorbidities. …”
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Changes in Running Kinematics and Kinetics Following a 10 km Run by Mark Reinking, Emily Hill, Kathryn Marr, Kasey Melness, Dominique Ortiz, Elsa Racasan, Nicholas Wedl, Joshua White, Brian Baum

“…This information has implications on risk of running-related injury. # Purpose The purpose of this study was to examine the effect of a 10 km run on running kinematics and kinetics in a sample of experienced runners…”
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Traumatic Fracture: Dislocation of Cervicothoracic Junction—Grand Round Presentation of C7-T1 Instabilities and Different Instrumentation Techniques by Mohammad A. Alsofyani, Soufiane Ghailane, Sultan Alsalmi, Sreenath Jakinapally, Louis Boissière, Ibrahim Obeid, Jean-Marc Vital

“…Initial CT scan shows vertebral body fracture of T1 with retropulsion into the spinal canal and anteroposterior dislocation of cervicothoracic junction type C according to AOSpine subaxial injury. Traumatic disc material at C7-T1 was removed by anterior cervical discectomy and fusion of C6-T2. …”
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KLF12 Aggravates Angiotensin II‐Induced Cardiac Remodeling in Male Mice by Transcriptionally Inhibiting SMAD7 by Min Hu, Shi‐Yu Huang, Yi‐Peng Gao, Yu‐Xin Hu, Sha‐Sha Wang, Teng Teng, Xiao‐Feng Zeng, Qi‐Zhu Tang

“…The KLF family of transcription factors plays crucial roles in heart injury. KLF12 (Krüppel‐like factor 12) is a transcription factor that regulates multiple disease processes, although the specific role of KLF12 in cardiac remodeling remains unclear. …”
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Hypermobile Anterior Horn of the Lateral Meniscus: A Case Report and Literature Review by Hirotaka Nakashima, Yasuhiro Takahara, Yoichiro Uchida, Hisayoshi Kato, Satoru Itani, Yoshitaka Tsujimura, Makoto Nakamura, Yuichi Iwasaki

“…The arthroscopic evaluation showed no meniscus and no other intraarticular injury. However, the anterior horn of the lateral meniscus was easily translated beyond the lateral condyle by using a probe. …”
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Dynamic Expression of HDAC3 in db/db Mouse RGCs and Its Relationship with Apoptosis and Autophagy by Yuhong Fu, Ying Wang, Xinyuan Gao, Huiyao Li, Yue Yuan

“…Histone deacetylase3 (HDAC3) is closely related to injury repair and nerve regeneration. The correlation between HDAC3 and retinal ganglion cells in diabetic retinopathy is still unclear yet. …”
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IVUS-Guided Zero-Contrast PCI in CKD Patients: Safety and Short-Term Outcome in Patients with Complex Demographics and/or Lesion Characteristics by Prathap Kumar, Blessvin Jino, Ali Shafeeq, Stalin Roy, Manu Rajendran, Sandheep George Villoth

“…Percutaneous coronary intervention (PCI) in patients with significant renal dysfunction is challenging because of the lesion characteristics and the risk of contrast-induced acute kidney injury (CI-AKI). With the advent of intravascular ultrasound- (IVUS-) guided zero-contrast PCI, outcomes have improved considerably. …”
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Professional and personal experiences of workplace violence among Italian mental health nurses: A qualitative study by Ilenia Piras, Igor Portoghese, Massimo Tusconi, Federica Minafra, Mariangela Lecca, Giampaolo Piras, Paolo Contu, Maura Galletta

“…Violence effects for healthcare professionals and organizations include an absence from work due to injury or illness, a decreased job satisfaction, and a lower quality of work. …”
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Clinical Outcome Discrimination in Pediatric ARDS by Chest Radiograph Severity Scoring by Yu-Chun Yan, Wen-Han Hao, Feng-Sen Bai, Shuang Liu, Dong Qu, Xin-Yu Yuan

“…Pediatric Acute Lung Injury Consensus Conference (PALICC) criteria were used to diagnose PARDS. …”
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Effectiveness of Percutaneous Hypodermic Needle Release of Trigger Finger: A Prospective Study by R Sahaya Jose, M Syed Moosa, SL Binesh

“…Only one patient (4%) developed digital nerve injury. Conclusion: Percutaneous hypodermic needle release for the trigger finger is a safe, effective, convenient, and inexpensive day-care procedure without any significant complications in the management of the trigger finger. …”
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MiR-18a-LncRNA NONRATG-022419 pairs targeted PRG-1 regulates diabetic induced cognitive impairment by regulating NGF\BDNF-Trkb signaling pathway by Qiong Xiang, Hu Lin, Jia-Sheng Tao, Chuan-Jun Fu, Li-Ni Liu, Jing Deng, Xian-Hui Li

“…In high glucose induced HT22 cells injury model in vitro, we investigated that down-regulated PRG-1 along with down-regulated BDNF and also decreased expression of synapsin-1, PSD-95, SYN which are related to synaptic plasticity; Meanwhile, the Prg-1 targeted miR-18a-LncRNA NONRATG-022419 pairs related with significantly down-regulated expression of PRG-1. …”
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Clinical Characteristics, Intraoperative Findings, and Surgical Outcomes of Canalicular Laceration Repair with Monocanalicular Stent in Asia by Chun-Hsien Lin, Chun-Yuan Wang, Ying-Cheng Shen, Li-Chen Wei

“…These were contributed by the avulsive eyelid injury mechanism caused by traffic accidents. Furthermore, the deeper lacerated site was located, and the lower anatomical and functional success rates were observed. …”
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Experience of nurse-guided root cause analysis after a sentinel event: a qualitative study by Li-Li Huang, Yan-Hong Jiang, Ju-Hong Yang, Wei-Wen Hong, Hai-Fei Chen, Wei-Wei Hu

“…Abstract Background Sentinel events, involving serious injury or death, reveal critical vulnerabilities in clinical practices. …”
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Liver diseases: epidemiology, causes, trends and predictions by Can Gan, Yuan Yuan, Haiyuan Shen, Jinhang Gao, Xiangxin Kong, Zhaodi Che, Yangkun Guo, Hua Wang, Erdan Dong, Jia Xiao

“…Various factors including viruses, alcohol, metabolites, toxins, and other pathogenic agents can compromise liver function, leading to acute or chronic injury that may progress to end-stage liver diseases. …”
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Assessment of Postresuscitation Volume Status by Bioimpedance Analysis in Patients with Sepsis in the Intensive Care Unit: A Pilot Observational Study by Bram Rochwerg, Jason H. Cheung, Christine M. Ribic, Faraz Lalji, France J. Clarke, Susheel Gantareddy, Nischal Ranganath, Aziz Walele, Ellen McDonald, Maureen O. Meade, Deborah J. Cook, Trevor T. Wilkieson, Catherine M. Clase, Peter J. Margetts, Azim S. Gangji

“…Secondary clinical outcomes included ventilator status and acute kidney injury. Proof of concept was sought by correlating baseline VL measurements with other known measures of volume status. …”
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