Early one-stage posterior-only surgery for congenital cervicothoracic scoliosis in children: medium- and long-term follow-up by Cefei Zhang, Fuyun Liu, Ke Xu, Weiming Hu, Bing Xia, Yufeng Zhao

“…One case of pleural rupture, three cases of transient nerve root injury, one case of Horner syndrome, and two cases of pleural effusion. …”
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REDD1 expression in podocytes facilitates renal inflammation and pyroptosis in streptozotocin-induced diabetic nephropathy by Siddharth Sunilkumar, Sandeep M. Subrahmanian, Esma I. Yerlikaya, Allyson L. Toro, Edward W. Harhaj, Scot R. Kimball, Michael D. Dennis

“…Abstract Sterile inflammation resulting in an altered immune response is a key determinant of renal injury in diabetic nephropathy (DN). In this investigation, we evaluated the hypothesis that hyperglycemic conditions augment the pro-inflammatory immune response in the kidney by promoting podocyte-specific expression of the stress response protein regulated in development and DNA damage response 1 (REDD1). …”
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The Application of Spleen-Preserving Splenic Regional Laparoscopic Lymphadenectomy with Spleen Kept In Situ and Laparotomy with Spleen Lifted Out of the Abdomen for Locally Advance... by Changrong Que, Shuangming Lin, Yibin Zhu, Dongbo Xu

“…The total number of lymph node dissection, intraoperative blood loss volume, intraoperative injury cases, and postoperative complications had no statistically significant difference between the two groups. …”
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Reversal of Early Diabetic Nephropathy by Islet Transplantation under the Kidney Capsule in a Rat Model by Yunqiang He, Ziqiang Xu, Mingshi Zhou, Minmin Wu, Xuehai Chen, Silu Wang, Kaiyan Qiu, Yong Cai, Hongxing Fu, Bicheng Chen, Mengtao Zhou

“…Twelve weeks later, the diabetic rats were divided into 3 groups: the islet-transplanted group (IT group), the insulin-treated group (IN group), and the untreated group (DN group). Renal injury and kidney structure were assessed by urinalysis and transmission electron microscopy (TEM) detection. …”
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Safety and Efficacy of Polyetheretherketone (PEEK) Cages and Cadaveric Allografts in Transforaminal Lumbar Interbody Fusion (TLIF) for Treating Lumbar Pyogenic Spondylodiscitis by Huo-Liang Zheng, Bo Li, Shao-Kuan Song, Peng-Bo Chen, Xin-Feng Zheng, Lei-Sheng Jiang, Sheng-Dan Jiang

“…An assessment of the residual pain, the grade of neurological injury, and the resolution of infection was conducted on 39 patients. …”
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Lebanese Cannabis sativa L. extract protects from cisplatin-induced nephrotoxicity in mice by inhibiting podocytes apoptosis by Alia Khalil, Sahar Al Toufaily, Wassim Shebaby, Marissa El Hage, Dima Mroue, Wissam Faour, Mohamad Mroueh

“…Methods Podocytes cell viability was assessed using MTS assay with cisplatin (30µM) in presence or absence of Cannabis oil extract (COE) at 0.5, 1 and 2µg/ml for 24h. Acute renal injury was established in adult female C57BL/6 mice with 20mg/kg, i.p. single dose cisplatin. …”
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YKL-40 as a Novel Factor Associated with Inflammation and Catabolic Mechanisms in Osteoarthritic Joints by Tuija Väänänen, Anna Koskinen, Erja-Leena Paukkeri, Mari Hämäläinen, Teemu Moilanen, Eeva Moilanen, Katriina Vuolteenaho

“…YKL-40 is associated with tissue injury and inflammation, and consequently to diseases in which these mechanisms lead to tissue degradation, for example, asthma and rheumatoid arthritis. …”
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Sacral Stress Fracture following the Bone Union of Lumbar Spondylolysis by Tatsuro Sasaji, Hideki Imaizumi, Hiroyuki Takano, Hideo Saitoh, Taishi Murakami, Ryuichi Kanabuchi, Motohiko Sekiya

“…While 22 articles have reported on sacral stress fractures, it is a rare injury and its etiology is not well known. We present the case of a 16-year-old male who presented with low back pain in 2015. …”
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Clinical Characteristics and Visual Outcomes of Patients Hospitalized for Ocular Trauma in Shandong Province, China by Fangnan Duan, Xiunian Chen, Sai Zhang, Xiaolin Qi, Weiyun Shi, Hua Gao

“…Of the mechanical eye injuries, there were 490 (34.4%) open-globe injuries and 454 (31.9%) closed-globe injuries. …”
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Better Functional Outcomes in Plate Fixation of Midshaft Clavicle Fracture in Dr. Soetomo General Academic Hospital by Mouli Edward, Steesy Benedicta, Teddy Heri Wardhana

“…Patients with a head injury, multiple traumas, re-fracture, malunion, open fracture, and pathological fracture were excluded. 161 patients remained. …”
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LIFU Alleviates Neuropathic Pain by Improving the KCC2 Expression and Inhibiting the CaMKIV–KCC2 Pathway in the L4–L5 Section of the Spinal Cord by Ye-Hui Liao, Bin Wang, Mo-Xian Chen, Yao Liu, Li-Juan Ao

“…We investigated the effect of LIFU on NP and on the expression of potassium chloride cotransporter 2 (KCC2) in the spinal cords of rats with peripheral nerve injury (PNI) in the lumbar 4–lumbar 5 (L4–L5) section. …”
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Spinal Reflex Recovery after Dorsal Rhizotomy and Repair with Platelet-Rich Plasma (PRP) Gel Combined with Bioengineered Human Embryonic Stem Cells (hESCs) by Mateus Vidigal de Castro, Moníze Valéria Ramos da Silva, Gabriela Bortolança Chiarotto, Maria Helena Andrade Santana, Ângela Cristina Malheiros Luzo, Sergiy Kyrylenko, Alexandre Leite Rodrigues de Oliveira

“…Dorsal root rhizotomy (DRZ) is currently considered an untreatable injury, resulting in the loss of sensitive function and usually leading to neuropathic pain. …”
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Evaluating Forelimb and Hindlimb Joint Conformation of Morna Racehorses (<i>Equus caballus</i>) by Israr Ahmad, Sahar Ijaz, Mirza M. Usman, Ayesha Safdar, Imdad U. Khan, Muhammad Zeeshan, Syed S. U. H. Bukhari

“…Measuring limb joint angles is crucial for understanding horse conformation, performance, injury diagnosis, and prevention. While Thoroughbred horses have been extensively studied, local Pakistani breeds (e.g., Morna racehorse) have not received scientific attention. …”
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Acute and Subchronic Toxicity Studies on the Aqueous Extract of the Plant Mixture (Bidens pilosa and Cymbopogon citratus Aerial Parts) in Rat Model by Yannick Carlos Tcheutchoua, Danielle Claude Bilanda, Yolande Sandrine Mengue Ngadena, Paul Désiré Djomeni Dzeufiet, Pascal Emmanuel Owona, Ronald Bidingha á Goufani, Rodrigue Ngapout Fifen, Lohik Mbolang Nguegan, Michel Noubom, Théophile Dimo, Pierre Kamtchouing

“…The study showed that the aqueous extract of the mixture of B. pilosa and C. citratus has a low toxicity and does not cause any injury to the liver, kidney, lungs, or spleen.…”
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Serum vascular endothelial growth factor levels as a marker of skin thickening, digital ischemia, and interstitial lung disease in systemic sclerosis by Chinnadurai Saranya, Ramamoorthy Ramesh, Mahendran Bhuvanesh, Chilukuri Balaji, Selvakumar Balameena, Sankaralingam Rajeswari

“…Background: Vascular injury is the initial event in the pathogenesis of systemic sclerosis (SSc) and potent proangiogenic mediators such as vascular endothelial growth factor (VEGF) are overexpressed in the skin and circulation of patients with SSc. …”
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Microglia Play a Major Role in Direct Viral-Induced Demyelination by Dhriti Chatterjee, Kaushiki Biswas, Soma Nag, S. G. Ramachandra, Jayasri Das Sarma

“…Microglia remain quiescent, unable to perform effector and antigen presentation (APC) functions until activated by injury or infection, and have been suggested to represent the first line of defence for the CNS. …”
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Elevated Troponin Serum Levels in Adult Onset Still’s Disease by Carlo Umberto Manzini, Lucio Brugioni, Michele Colaci, Maurizio Tognetti, Amelia Spinella, Marco Sebastiani, Dilia Giuggioli, Clodoveo Ferri

“…These observations suggest that early myocardial injury might be underestimated or entirely overlooked in patients with AOSD; routine cardiac assessment including troponin evaluation should be mandatory in all patients with suspected AOSD.…”
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The Role of Fatigue in Return to Sport Testing Following Anterior Cruciate Ligament Reconstruction by Justin C Tallard, Corbin Hedt, Bradley S Lambert, Patrick C McCulloch

“…# Background Fatigue may play a role in anterior cruciate ligament (ACL) injury, but has not been incorporated into objective test batteries for return to sport decisions following ACL reconstruction (ACLR) surgery. …”
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Detection of exhaled methane levels for monitoring trauma-related haemorrhage following blunt trauma: study protocol for a prospective observational study by Péter Jávor, Ferenc Rárosi, Tamara Horváth, László Török, Endre Varga, Petra Hartmann

“…We also hypothesise that exhaled CH4 levels reflect the volume of blood loss more accurately than conventional markers of blood loss and shock such as shock index, haemoglobin, base deficit, lactate, end-tidal carbon dioxide and sublingual microcirculatory indices.Methods and analysis One hundred and eleven severely injured (Injury Severity Score ≥16), intubated, bleeding patients sustaining blunt trauma will be included in this prospective observational study. …”
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Feasibility and acceptability for LION, a fully remote, randomized clinical trial within the VA for light therapy to improve sleep in Veterans with and without TBI: An MTBI2 sponso... by Jonathan E Elliott, Jessica S Brewer, Allison T Keil, Brittany R Ligman, Mohini D Bryant-Ekstrand, Alisha A McBride, Katherine Powers, Savanah J Sicard, Elizabeth W Twamley, Maya E O'Neil, Andrea D Hildebrand, Thuan Nguyen, Benjamin J Morasco, Jessica M Gill, Bradley A Dengler, Miranda M Lim

“…Sleep-wake disturbances frequently present in Veterans with mild traumatic brain injury (mTBI). These TBI-related sleep impairments confer significant burden and commonly exacerbate other functional impairments. …”
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