Effect of Carboxymethyl chitosan-sodium alginate hydrogel loaded with Astragalus membranaceus-Panax notoginseng on wound healing in rats by Jing Li, Jing Li, Linai Li, Yue Yu, Ruixin Qin, Chaoyan Yu, Chen Chen, Youming Dong, Yadong Tan, Yunen Liu, Xuanli Liu

“…In traditional Chinese medicine, A. membranaceus and Panax notoginseng are commonly used together for the treatment of wound injury for their significant efficacy. The application of new materials may make A. membranaceus-P. notoginseng (AP) play a better curative effect. …”
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Pleomorphic Adenoma of the Parotid: Extracapsular Dissection Compared with Superficial Parotidectomy—A 10-Year Retrospective Cohort Study by Maria Giulia Cristofaro, Eugenia Allegra, Amerigo Giudice, Walter Colangeli, Davide Caruso, Ida Barca, Mario Giudice

“…Transient facial nerve injury and facial paralysis were significantly more frequent after SP than after ED (P=0.001 and P=0.065, resp.). …”
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UHRF1 promotes epithelial-mesenchymal transition mediating renal fibrosis by activating the TGF-β/SMAD signaling pathway by Lijie Yang, Penghui Si, Tuoheti Kuerban, Linfa Guo, Shanzhi Zhan, Yisha Zuhaer, Yingtong Zuo, Peixiang Lu, Xiaojie Bai, Tongzu Liu

“…The process of epithelial-mesenchymal transition (EMT) plays a critical role in the progression of fibrosis following renal injury. UHRF1, as a critical epigenetic regulator, may play an essential role in the pathogenesis and progression of renal fibrosis and EMT. …”
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Drought before fire increases tree mortality after fire by C. Alina Cansler, Micah C. Wright, Phillip J. vanMantgem, Timothy M. Shearman, J. Morgan Varner, Sharon M. Hood

“…We used Bayesian hierarchical modeling to predict the probability of individual tree mortality after fire based on species—Pinus contorta (lodgepole pine), Abies concolor (white fir), Pseudotsuga menziesii (Douglas‐fir), and Pinus ponderosa (ponderosa pine)—bark thickness, bark char, percentage live tree crown scorched or consumed crown volume scorch (CVS), and mean annual climatic water deficit (CWD) anomalies the year pre‐fire and fire year relative to the 1985–2015 reference period. Although crown injury was the primary determinant of tree mortality after fire, drought increased likelihood of death, with a 2‐SD increase in CWD (+115.7) resulting in a 78% increase in the probability of mortality. …”
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In Vivo Assessment of Healing Potential of Ointments Containing Bee Products, Vegetal Extracts, and Polymers on Skin Lesions by Calin Vasile Andritoiu, Cristina Lungu, Camelia Elena Iurciuc (Tincu), Corina Elena Andriescu, Corneliu Havarneanu, Marcel Popa, Magdalena Cuciureanu, Liliana Mititelu Tarţău, Bianca Ivanescu

“…<b>Conclusions</b>: The tested ointments exerted in vivo wound healing and re-epithelialization effects on incision, excision, and thermal burn injuries.…”
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Incidence and fatality of serious suicide attempts in a predominantly rural population in Shandong, China: a public health surveillance study by Aiqiang Xu, Mei Wang, Xiaolei Guo, Cunxian Jia, Jiandong Sun, Jiyu Zhang

“…Linked data from two public health surveillance systems were analysed.Setting Three selected counties in Shandong, China.Participants All residents in the three selected counties.Outcome measures Incidence rate (per 100 000 person-years) and case fatality rate (%).Methods Records of suicide deaths and hospitalisations that occurred among residents in selected counties during 2009–2011 (5 623 323 person-years) were extracted from electronic databases of the Disease Surveillance Points (DSP) system and the Injury Surveillance System (ISS) and were linked by name, sex, residence and time of suicide attempt. …”
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HSPB1 Regulates Autophagy and Apoptosis in Vascular Smooth Muscle Cells in Arteriosclerosis Obliterans by Keqin Chen, Changmiao Hou, Lei Xu, Hanwu Peng, Chaogui He, Jing Liu, Guoqing Wang, Shaoshuai Huang, Xiehong Liu

“…Small heat shock protein-1 (HSPB1) is a small heat shock protein that participates in many cellular processes and alleviates stress-induced cell injury. Autophagy protects cells from many types of stress and plays a key role in preventing stress in arteriosclerosis obliterans (ASO). …”
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MicroRNAs in the DNA Damage/Repair Network and Cancer by Alessandra Tessitore, Germana Cicciarelli, Filippo Del Vecchio, Agata Gaggiano, Daniela Verzella, Mariafausta Fischietti, Davide Vecchiotti, Daria Capece, Francesca Zazzeroni, Edoardo Alesse

“…Impairment in the DNA repair proteins, which physiologically protect cells from persistent DNA injury, can affect the efficacy of cancer therapies. …”
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Neural Mobilization Treatment Decreases Glial Cells and Brain-Derived Neurotrophic Factor Expression in the Central Nervous System in Rats with Neuropathic Pain Induced by CCI in R... by Aline Carolina Giardini, Fabio Martinez dos Santos, Joyce Teixeira da Silva, Mara Evany de Oliveira, Daniel Oliveira Martins, Marucia Chacur

“…Here we examined the involvement of glial cells and BDNF expression in the thalamus and midbrain after NM treatment in rats with chronic constriction injury (CCI). CCI was induced and rats were subsequently submitted to 10 sessions of NM, every other day, beginning 14 days after CCI. …”
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The Effect of Hyperbaric Oxygen Therapy on Functional Impairments Caused by Ischemic Stroke by Emily R. Rosario, Stephanie E. Kaplan, Sepehr Khonsari, Garrett Vazquez, Niyant Solanki, Melanie Lane, Hiriam Brownell, Sheila S. Rosenberg

“…While research suggests a benefit of hyperbaric oxygen therapy (HBOT) for neurologic injury, controlled clinical trials have not been able to clearly define the benefits. …”
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PAC-Mediated AKI Protection Is Critically Mediated but Does Not Exclusively Depend on Cell-Derived Microvesicles by H. Dihazi, K. Schwarze, S. Patschan, G. A. Müller, O. Ritter, M. Zeisberg, D. Patschan

“…Introduction. Acute kidney injury (AKI) significantly worsens the prognosis of hospitalized patients. …”
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Morphological Features and In Vitro Cytopathic Effect of Acanthamoeba griffini Trophozoites Isolated from a Clinical Case by Arturo González-Robles, Lizbeth Salazar-Villatoro, Maritza Omaña-Molina, Maria Reyes-Batlle, Carmen M. Martín-Navarro, Jacob Lorenzo-Morales

“…When epithelial monolayers were incubated with conditioned medium for 24 h, small areas of cell injury were also observed. The phylogenetical analysis as well as the sequencing of the acquired amplified product for the DF3 region of the amoebae isolate confirmed that it belongs to genotype T3, which includes other pathogenic amoebae; besides the activity of two drugs currently used against Acanthamoeba was tested on A. griffini.…”
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Escherichia coli in the T11-12 Thoracic Vertebrae: A Case Report by Weng D, Zhou H, Huang G, Cao Q, Wang H, Cao Z, Xie Q

“…Dandan Weng,1,&ast; Hongyuan Zhou,1,&ast; Guancheng Huang,1 Qingren Cao,2 Huafeng Wang,3 Zhujun Cao,2 Qing Xie2 1Department of Infectious Diseases, Yuyao People’s Hospital, Ningbo, Zhejiang, People’s Republic of China; 2Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Qing Xie; Zhujun Cao, Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Ruijin Er Road, Shanghai, 200025, People’s Republic of China, Email xieqingrjh@163.com; estherlucifer@163.comBackground: Pyogenic thoracic spondylitis is a rare but severe infection, particularly when complicated by sepsis and acute kidney injury (AKI). Early diagnosis and precise management are essential for improving outcomes, given the limitations of traditional microbiology detection methods in identifying the causative pathogens.Case Presentation: A 68-year-old immunocompetent male presented with recurrent fever, fatigue, loss of appetite and initial evidence of sepsis and AKI upon admission. …”
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Complement Factor H Gene Variant in a Patient with Thrombotic Microangiopathy on a Mixed Clinical Background by Yoichi Iwafuchi, Tetsuo Morioka, Yuko Oyama, Shin Goto, Ichiei Narita

“…About 13 weeks prior to her transfer to our hospital, she was referred to another hospital due to acute kidney injury, hemolytic anemia, and thrombocytopenia. Hemodialysis was immediately initiated, after which intravenous methylprednisolone and oral prednisolone were started; however, she became anuric within approximately week. …”
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Poly-L-Arginine Induces Apoptosis of NCI-H292 Cells via ERK1/2 Signaling Pathway by Ya-Ni Wang, Ling-Ling Zhang, Xiao-Yun Fan, Sha-Sha Wu, Sheng-Quan Zhang

“…Besides, inhibition of cationic protein-induced apoptotic death in airway epithelial cells could be considered as a potential target of anti-injury or antiremodeling in asthmatics.…”
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A case report: interstitial pneumonia following treatment of gastric cancer with sintilimab in combination with S-1 by Pei Zhu, Qingming Sun, Sheng Xu, Wanhui Dong

“…If drug-induced lung injury is suspected, the medication should be discontinued immediately, and appropriate treatment should be initiated promptly.…”
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Modulation of biological activities in adipose derived stem cells by histone deacetylation by Sallam Abdallah, Mouna Tabebi, Sawsan Qanadilo, Neserin Ali, Jing Wang, Pádraig D’Arcy, Wen Zhong, Folke Sjoberg, Moustafa Elmasry, Ahmed El-Serafi

“…Exploring epigenetic regulation in adipose-derived stem cells (ADSCs) holds promise for improving skin injury treatments. We investigated the effects of histone deacetylase inhibitor (SAHA) on ADSCs to better understand its cellular and molecular impacts. …”
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Risk Factors for Stress Fractures in Female Runners: Results of a Survey by Therese E Johnston, Allison E Jakavick, Caroline A Mancuso, Kathleen C McGee, Lily Wei, Morgan L Wright, Jeremy Close, Ayako Shimada, Benjamin E Leiby

“…Questions included demographics, running details, cross training, nutrition, injury history, medical/menstrual history, and medications. …”
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An exploration of the increasing prevalence of chronic pain among Canadian veterans: Life After Service Studies 2016 and 2019 by Jhalok Ronjan Talukdar, Dena Zeraatkar, Andrew Thomas, Jason W. Busse

“…Respondents who completed the 2019 LASS were more likely to endorse an anxiety or related disorder, mood disorder, probable posttraumatic stress disorder, and traumatic brain injury. In our adjusted regression model, year of survey administration was not associated with chronic pain (OR = 1.08, P = 0.8); however, we found large associations with obesity class 1 (body mass index [BMI] = 30.0–34.9; OR = 3.66; 95% confidence interval [CI] 1.46–9.17; ARI 27%), obesity class 2 (BMI = 35.0–39.9; OR = 8.10; 95% CI 1.67–39.3; ARI 47%), mood disorder (OR = 3.20; 95% CI 1.49–6.88; ARI 24%), and an anxiety or related disorder (OR = 4.53; 95% CI 1.28–16.0; ARI 33%).Conclusions The increase in chronic pain among Canadian veterans from 2016 to 2019 appears confounded by increased comorbidities associated with chronic pain among responders in 2019.…”
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Serum Levels of IL-33 and Correlation with IL-4, IL-17A, and Hypergammaglobulinemia in Patients with Autoimmune Hepatitis by Ma Liang, Zhang Liwen, Zhuang Yun, Ding Yanbo, Chen Jianping

“…Additionally, the serum levels of IL-33 in AIH patients were correlated positively with markers of hypergammaglobulinemia (IgG, IgM, and IgA) and liver injury (γ-GT/ALP). Also, the serum levels of IL-33 in AIH patients were correlated positively with proinflammatory cytokine levels (IL-17A and IL-4). …”
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