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4441
OMP38 of Carbapenem‐Resistant Acinetobacter Baumannii‐Mediated mtDNA Release Activates the cGAS‐STING Signaling to Induce Inflammatory Response
Published 2025-01-01“…The knockout of STING reduced bacterial burden, the production of inflammatory cytokines, and lung injury in mice post CRAB infection. The cytosolic DNA sensor cyclic GMP‐AMP synthase (cGAS) and the adaptor protein stimulator of interferon genes (STING) are required for CRAB‐induced IFN‐β expression in macrophages. …”
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4442
Causes of death among older children and adolescents (5–19 years) in the Magu Health and Demographic Surveillance Study, Tanzania, 1995–2022
Published 2024-12-01“…Non-communicable diseases and injuries gained importance, with their relative share of all deaths increasing from 15% in 1995–2004 to 58% in 2015–2022. …”
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4443
Intra-Articular Injection of Human Bone Marrow–Derived Mesenchymal Stem Cells in Knee Osteoarthritis: A Randomized, Double-Blind, Controlled Trial
Published 2025-01-01“…Changes in the visual analog scale (VAS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Knee Injury and Osteoarthritis Outcome Score (KOOS) after IA injection were assessed at 3, 6, 9, and 12 months. …”
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4444
Influence of Different ECM-Like Hydrogels on Neurite Outgrowth Induced by Adipose Tissue-Derived Stem Cells
Published 2017-01-01“…Mesenchymal stem cells (MSCs) have been proposed for spinal cord injury (SCI) applications due to their capacity to secrete growth factors and vesicles—secretome—that impacts important phenomena in SCI regeneration. …”
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4445
miR-432-5p Inhibits the Ferroptosis in Cardiomyocytes Induced by Hypoxia/Reoxygenation via Activating Nrf2/SLC7A11 Axis by Degrading Keap1
Published 2023-01-01“…Early reperfusion into the myocardium after ischemia causes myocardial ischemia–reperfusion (I/R) injury and ferroptosis was involved. Ischemia activates the expression of a series of oxidative stress genes and their downstream regulatory genes, including ferroptosis-related genes such as nuclear factor E2-related factor 2 (Nrf2), glutathione peroxidase 4 (GPX4), and SLC7A11. …”
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4446
Plant growth-promoting bacteria and nanomaterials synergism to enhance Lolium perenne growth and phytoremediation in cadmium-contaminated soil
Published 2025-03-01“…The PGPB-GNPs combination also reduced the Cd-induced stress injury to ryegrass through increased production of antioxidants. …”
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4447
Novel Organic Mineral Complex Prevents High-Fat Diet-Induced Changes in the Gut and Liver of Male Sprague-Dawley Rats
Published 2020-01-01“…Prior research shows that a proprietary soil-derived organic mineral complex (OMC) prevents hyperglycemia, endotoxemia, and liver injury in rats fed a high-fat diet (HFD) for 10 weeks. …”
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4448
The Localization Research of Brain Plasticity Changes after Brachial Plexus Pain: Sensory Regions or Cognitive Regions?
Published 2019-01-01“…Neuropathic pain after brachial plexus injury remains an increasingly prevalent and intractable disease due to inadequacy of satisfactory treatment strategies. …”
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4449
Comparison of 8 Weeks of Selected TRX Training and Weight Training on Improving Motor Function and Chronic Nonspecific Back Pain in Women Aged 35 to 55
Published 2024-08-01“…These exercises appear to lower the risk of injury and enhance performance by improving motor function. …”
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4450
Designing Microfluidic Devices to Sort Haematopoietic Stem Cells Based on Their Mechanical Properties
Published 2019-01-01“…Few haematopoietic stem cells (HSCs) injected systemically for therapeutic purposes actually reach sites of injury as the vast majority become entrapped within pulmonary capillaries. …”
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4451
Long-term copper exposure induced pyroptosis and inflammation of rat spleen through intestinal-splenic axis
Published 2025-01-01“…These findings offer a novel perspective on how copper may induce spleen injury through the intestine-spleen axis.…”
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4452
Anti-Inflammatory and Antioxidant Effects of Carpesium cernuum L. Methanolic Extract in LPS-Stimulated RAW 264.7 Macrophages
Published 2020-01-01“…Additionally, oxidative stress has been identified to induce severe tissue injury and inflammation. Carpesium cernuum L. (C. cernuum) is a Chinese folk medicine used for its anti-inflammatory, analgesic, and detoxifying properties. …”
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4453
Correlation between oxygen reserve index monitoring and blood gas oxygen values during anesthesia in robotic total prostatectomy surgery
Published 2025-01-01“…Abstract Introduction-objective Hyperoxia is associated with acute lung injury and atelectasis. Arterial blood gas measurement is an invasive method. …”
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4454
Disability weights for environmental noise-related health states: results of a disability weights measurement study in Europe
Published 2024-04-01“…Introduction Measurement of the burden of disease using disability-adjusted life years requires disability weights to quantify health losses for non-fatal consequences of disease and injury. We aimed to obtain a set of disability weights for environmental and non-environmental noise-related health states (NOISE) using a nationally representative sample survey among the general population of four European countries; and to compare the resulting NOISE disability weights with those estimated in the Global Burden of Disease 2010 (GBD 2010) and European (EURO) disability weights measurement studies.Methods We administered a web-based survey among a cohort of individuals from Hungary, Italy, Sweden and the Netherlands. …”
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4455
Factors associated with post-hospitalization dialysis dependence in ECMO patients who required continuous renal replacement therapy
Published 2024-12-01“…Objective This single center retrospective study aimed to describe the variables associated with outpatient dialysis dependence in extracorporeal membrane oxygenation (ECMO) patients who needed continuous renal replacement therapy (CRRT) for acute kidney injury (AKI) during their hospitalization.Methods Retrospective study of patients who required ECMO-CRRT.Results Between the years of 2016 and 2022, 202 patients required ECMO-CRRT. …”
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4456
The impaired response of nasal epithelial cells to microplastic stimulation in asthma and COPD
Published 2025-02-01“…Abstract Microplastic particles from the air are inhaled and accumulate in the lungs, potentially causing immunological reactions and airway tissue injury. This study aimed to evaluate the biological effects of polyamide fibres on nasal epithelium co-cultivated with macrophages in control, asthma, and COPD groups. …”
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4457
Effects of falls prevention interventions on falls outcomes for hospitalised adults: protocol for a systematic review with meta-analysis
Published 2017-11-01“…Introduction Falls are a major global public health problem and leading cause of accidental or unintentional injury and hospitalisation. Falls in hospital are associated with longer length of stay, readmissions and poor outcomes. …”
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4458
Tailored exercise and manual therapy versus standardised exercise for patients with shoulder subacromial pain: a feasibility randomised controlled trial (the Otago MASTER trial)
Published 2022-06-01“…Adverse events (n=2, only in the tailored group) were minor in nature and included skin injury or pain following taping.Conclusions Our feasibility trial showed that additional strategies are required for improving recruitment, enrolment and minimising drop-out of participants into the trial and making it feasible to conduct a full trial.Trial registration number ANZCTR: 12617001405303.…”
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4459
N-Cadherin Upregulation Promotes the Neurogenic Differentiation of Menstrual Blood-Derived Endometrial Stem Cells
Published 2018-01-01“…Peripheral nerve injuries are typically caused by either trauma or medical disorders, and recently, stem cell-based therapies have provided a promising treatment approach. …”
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4460
Design, synthesis and biological evaluation of buthutin derivatives as cardioprotective agents
Published 2025-02-01“…In this study, twenty-nine buthutin derivatives were designed, synthesized, and evaluated for their NHE-1 inhibition and protective effects on cardiomyocyte injury. The structure of the newly synthesized compounds had been confirmed by 1H-NMR, 13C-NMR, and HR-ESI-MS spectra. …”
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