RIPK1 in necroptosis and recent progress in related pharmaceutics by Kunhou Yao, Zhihao Shi, Fengya Zhao, Cong Tan, Yixin Zhang, Hao Fan, Yingzhe Wang, Xingwang Li, Jun Kong, Qun Wang, Dingxi Li

“…RIPK1-mediated necroptosis further promotes cell death and inflammation in the pathogenesis of liver injury, skin diseases, and neurodegenerative diseases. …”
Get full text

Myofibroblast-derived exosomes enhance macrophages to myofibroblasts transition and kidney fibrosis by Wenqiang Yu, Jinfang Song, Shuangquan Chen, Jiayi Nie, Chujun Zhou, Jiamin Huang, Hua Liang

“…Mice treatment with myofibroblast-derived exosomes (Myo-Exo) exhibited severe fibrotic lesion and more abundant MMT cells in kidneys with folic acid (FA) injury, which was negated by TANK-banding kinase-1 inhibitor. …”
Get full text

Effects of Late Evening Snack on Cirrhotic Patients: A Systematic Review and Meta-Analysis by Ying-jie Guo, Zi-bin Tian, Na Jiang, Xue-li Ding, Tao Mao, Xue Jing

“…However, it may have little effect on reducing liver parenchymal injury indexes such as serum aminotransferase.…”
Get full text

Management of COVID-19 in Kidney Transplant Recipients: A Single-Center Case Series by Maruhum Bonar H. Marbun, Riahdo J. Saragih, Tantika Andina

“…The mortality rate was 42.1%. Acute kidney injury (AKI) was present in six (31.6%) of KTRs, five (83.3%) of whom were nonsurvivors. …”
Get full text

Ischemia Elicits a Coordinated Expression of Pro-Survival Proteins in Mouse Myocardium by Deborah Lyn, Shaojia Bao, Nicole A. Bennett, Xiaowei Liu, Nerimiah L. Emmett

“…To gain an understanding of the factors involved with ischemic injury, we examined expression changes in pro-survival and opposing pro-apoptotic signals at early and chronic periods of ischemia using an in vivo murine model. …”
Get full text

Achilles Rupture Repair: Modified Gift-Box With a Proximal Myotendinous Backup Fixation Technique by Nicholas D. Cominos, B.S., Joseph S. Tramer, M.D., Andrew J. Peace, M.D., Matthew A. Zaborowicz, M.D., Erik B. Eller, M.D., Lafi S. Khalil, M.D.

“…Achilles tendon tears are not an uncommon injury, with a predominance in explosive athletes and weekend warriors in the third to fifth decade of life. …”
Get full text

COVID-19 and APOL-1 High-Risk Genotype-Associated Collapsing Glomerulonephritis by Sasmit Roy, Srikanth Kunaparaju, Narayana Murty Koduri, Vikram Sangani, Mytri Pokal, Venu Madhav Konala, Mamtha Balla, Sreedhar Adapa

“…Though primarily affecting the lungs, it has also affected the kidney in various ways including acute kidney injury (AKI), proteinuria, and hematuria. It has been increasingly shown that African American (AA) individuals affected with COVID-19 and presenting with AKI and nephrotic-range proteinuria are very susceptible to focal segmental glomerulosclerosis (FSGS). …”
Get full text

Damage Control Laparotomy in Trauma Patients: A Level I Trauma Center Experience by Anthony J. Duncan, Wade A. Hopper, Mentor Ahmeti

“…Introduction: The surgical management of traumatic injury is an evolving and controversial topic. We present outcomes of laparotomy performed for blunt and penetrating trauma at a level I trauma center over a nearly 10-year period. …”
Get full text

Age-related changes in the vestibulothalamic pathway: Association with balance ability and subjective visual vertical of vestibular function by Sang Seok Yeo, Seo Yoon Park, In Hee Cho

“…Therefore, the study could be helpful in providing the data for patients with thalamus or vestibular injury.…”
Get full text

Association between non-high-density lipoprotein cholesterol-to-high-density lipoprotein cholesterol ratio and macroalbuminuria: evidence from NHANES 1999-2018 by Dongli Huang, Yuan He

“…However, its relationship with kidney injury, particularly albuminuria, remains poorly understood. …”
Get full text

Novel delivery systems for phages and lysins in the topical management of wound infections: a narrative review by Pan Yang, Jing Li, Xiumei Ma, Nan Hu, Zhangyong Song, Bin Chen, Shizhu Li

“…The findings highlighted the positive effects of the five novel delivery systems for phages and lysins in WI management, significantly reducing wound bacterial populations, and accelerating healing at the injury site. However, the available literature on novel delivery systems for phages and lysins remains limited, particularly for lysins. …”
Get full text

Acute Interstitial Nephritis in a Patient with Non-Small Cell Lung Cancer under Immunotherapy with Nivolumab by Panagiotis I. Georgianos, Vasilios Vaios, Eleni Leontaridou, Georgia Karayannopoulou, Triantafyllia Koletsa, Athanasios Sioulis, Elias V. Balaskas, Pantelis E. Zebekakis

“…We present the case of a 60-year-old man with a history of non-small cell lung cancer, who developed acute kidney injury (AKI) approximately 3.5 months after initiation of immunotherapy with nivolumab. …”
Get full text

Simultaneous Bilateral Proximal Humerus Fractures Treated with Single-Stage Bilateral Reverse Shoulder Arthroplasty by Taiki Tokuhiro, Atsushi Urita, Yusuke Kameda, Makoto Motomiya, Naoya Watanabe, Norimasa Iwasaki

“…Single-stage bilateral RSA was performed 9 days after the injury. An abduction pillow was applied for 5 weeks postoperatively. …”
Get full text

Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Alveolar Type II Cell Proliferation and Attenuate Lung Inflammation in a Rat Model of Bronchopulmonar... by Ou Zhou, Jingyi You, Xiaochuan Xu, Jiang Liu, Huijun Qiu, Chang Hao, Wenjing Zou, Wenjie Wu, Zhou Fu, Daiyin Tian, Lin Zou

“…Although it is known that exosomes derived from human umbilical cord mesenchymal stem cells (hUCMSCs) alleviate hyperoxic lung injury of bronchopulmonary dysplasia (BPD) in animal models, the role of microvesicles (MVs) derived from hUCMSCs in BPD is poorly defined. …”
Get full text

An Analysis of the Effects of Crash Factors and Precrash Actions on Side Impact Crashes at Unsignalized Intersections by Emmanuel Kofi Adanu, Xiaobing Li, Jun Liu, Steven Jones

“…It was observed that side impact crashes that occurred under daylight conditions at four-way intersections, for instance, were less likely to involve running a stop sign but more likely to involve failure to yield at the stop sign and failure to yield right-of-way at a turn, but under dark and unlit roadway conditions, the at-fault drivers were more likely to run a stop sign or fail to yield at a stop sign but less likely to be involved in failure to yield right-of-way at a turn. This approach to injury severity analysis uncovers complex underlying relationships between precrash actions, other contributing factors, and crash outcomes.…”
Get full text

IL-6-mediated MHC class II induction on RIN-5AH insulinoma cells by IFN-γ occurs via the G-protein pathway by S. Vassiliadis, G. K. Papadopoulos

“…Other cytokines such as IL-1α and β, and TNF-α induce a smaller increase in MHC class II antigens on RIN cells, and appear to activate both the G-protein and the PKC signal transduction pathways to varying degrees. Therefore, injury of pancreatic β-cells and possible induction of autoimmune type 1 diabetes via various cytokines may be caused by IL-6 or IFN-γ, or by their ability to induce MHC class II antigen upregulation.…”
Get full text

STAT3 inhibition ameliorates renal interstitial inflammation in MRL/lpr mice with diffuse proliferative lupus nephritis by Jianfen Zhu, Yijing Chen, Yulan Chen, Yinqiu Lv, Tianxin Chen

“…Background and objectives Acute kidney injury (AKI) is one of the most common and severe clinical syndromes of diffuse proliferative lupus nephritis (DPLN), of which poor prognosis is indicated by aggravated renal function deterioration. …”
Get full text

Aetiologies and Management of Retropharyngeal Abscess in Paediatric Age Group by Prem Kumar, Abhilasha Somashekhar

“…One child had sustained injury to neck, and one had history of chicken bone ingestion. …”
Get full text

The Case for Musical Instrument Training in Cerebral Palsy for Neurorehabilitation by Ana Alves-Pinto, Varvara Turova, Tobias Blumenstein, Renée Lampe

“…Recent imaging studies in cerebral palsy (CP) have described several brain structural changes, functional alterations, and neuroplastic processes that take place after brain injury during early development. These changes affect motor pathways as well as sensorimotor networks. …”
Get full text

Hubungan Lama Terapi Antipsikotik dengan Kadar SGOT dan SGPT pada Pasien Skizofrenia di RSJ Prof. H.B Sa’anin, Padang Tahun 2013 by Cahyaningtyas Cahyaningtyas, Rahmatini Rahmatini, Kurniawan Sedjahtera

“…Beberapa antipsikotik, diantaranya klorpromazin, haloperidol, dan risperidon, telah diselidiki dapat menyebabkan drugs-induced liver injury, berupa kolestasis dan kerusakan hepatoselular. …”
Get full text