Placental trophoblast aging in advanced maternal age is related to increased oxidative damage and decreased YAP by Song Guo, Song Guo, Qihao Pan, Qihao Pan, Baokang Chen, Baokang Chen, Yijuan Huang, Yijuan Huang, Si Li, Si Li, Chenyu Gou, Chenyu Gou, Yu Gao, Yu Gao

“…Therefore, this study explored the relationship between trophoblast cell aging and oxidative injury and YAP in AMA pregnancy, which not only provided an insight into the mechanisms of trophoblast cell aging, but also provide valuable directions for healthcare during AMA pregnancy.MethodsIn this study, human term placentas were collected from AMA and normal pregnancies for the analysis of aging, oxidative damage and YAP level. …”
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Promotion of microfracture-mediated cartilage repair by the intra-articular injection of Mg2+ by Zhian Chen, Tianhua Zhou, Zhengbo Yin, Peiya Duan, Ying Zhang, Yujiao Feng, Rongmao Shi, Yongqing Xu, Rongqing Pang, Hongbo Tan

“…The new cartilage coverage in the injury area was more complete, and the regeneration of hyaline cartilage was higher. …”
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An Ultrasound-Assisted Technique to Fix the Avulsion Fracture of the Posterior Tibial Spine by Gautam Kumar, Biju Jacob, Jefin Jose Edakalathur, Lazar J. Chandy, Rajesh Simon

“…Background: The fixation of posterior tibial avulsion fractures has been predominantly open reduction and internal fixation that leads to longer incision, severe scarring and higher risk to neurovascular injury while using the posterior approach. The arthroscopic methods have a steep learning curve, and fracture fixation is usually with fibre wire. …”
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Application the Risk-Based Maintenance for Optimizing the Overall Medical Devices Safety by Khelood A. Mkalaf, Peter Gibson

“…Which, can affect the reputation of hospitals following the exposure of patients' lives to various risks like death, injury, and misdiagnosis. Furthermore, a sudden failure will lead to increased economic losses as a result of increased maintenance costs.  …”
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High-Grade Leiomyosarcoma Arising in a Previously Replanted Limb by Tiffany J. Pan, Liron Pantanowitz, Kurt R. Weiss

“…Development of leiomyosarcoma in this case could be related to revascularization, scar formation, or chronic injury after replantation. The patient remains healthy without signs of recurrence at three-year follow-up.…”
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Flexor Digitorum Accessorius Longus: Importance of Posterior Ankle Endoscopy by Jorge Pablo Batista, Jorge Javier del Vecchio, Pau Golanó, Jordi Vega

“…We recommend this treatment on this type of injury although we admit this does not make a definite conclusion.…”
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Displacement MMG-based estimation of dynamic muscle viscoelasticity in the quadriceps during passive pedaling by Shinichi Fukuhara, Hisao Oka

“…These findings can enhance the evaluation of muscle performance, contracture, atrophy, and injury prevention in both rehabilitation and sports settings.…”
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Panic Disorder Induced by the Coronavirus Disease Pandemic in a Patient with Organic Mood Disorder Successfully Treated with Vortioxetine by Reiji Yoshimura, Naomichi Okamoto, Yuki Konishi, Atsuko Ikenouchi

“…The patient was a 62-year-old woman with mild mood swings and reduced motivation and volition caused by a traumatic brain injury after a traffic accident. She was maintained on carbamazepine (600 mg/day). …”
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X-Ray-Based 3D Histopathology of the Kidney Using Cryogenic Contrast-Enhanced MicroCT by Arne Maes, Onno Borgel, Clara Braconnier, Tim Balcaen, Martine Wevers, Rebecca Halbgebauer, Markus Huber-Lang, Greet Kerckhofs

“…This optimized protocol showed to be highly sensitive, allowing to detect small pathology-induced microstructural changes in a mouse model of mild trauma-related acute kidney injury after thorax trauma and hemorrhagic shock. …”
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Disturbance of Inorganic Phosphate Metabolism in Diabetes Mellitus: Its Relevance to the Pathogenesis of Diabetic Retinopathy by H. Vorum, J. Ditzel

“…Any interruption of optimal ATP production might lead to cell injury and possible cell death, and evidence will be provided herein that such cell death does occur in diabetic retinopathy. …”
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Evaluation of Finger Prints in Relation to Academic Performance of Students in Anatomy at Islam Medical and Dental College, Sialkot by Muhammad Junaid, Riaz Ahmad, Naureen Waseem, Aftab Ahmad, Aaqiba Rasheed, Rana Muhammad Zeeshan, Ayesha Riaz

“…A total of 300 healthy medical (1st and 2nd year MBBS) and dental (1st year BDS) students with no injury and deformity, voluntarily participated in this study. …”
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Adult Intestinal Malrotation Treated with Laparoscopic Ladd Procedure by Noritoshi Mizuta, Takuya Kikuchi, Yoshiyuki Fukuda

“…The reason for reoperation in one of the cases is considered to be pancreatic injury when the severe curve from the duodenum to the upper jejunum near the pancreatic head was straightened. …”
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Early Recurrence of Ovarian Cancer during Pregnancy after Primary Staging Surgery in the First Trimester by Munetoshi Akazawa, Kazunori Hashimoto

“…We performed emergent cesarean section, diagnosing acute kidney injury during pregnancy. On surgical finding, there were a number of 1 cm sized nodules in the small bowel wall and peritoneum. …”
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A New Challenging Strategy in the Prevention and Management of Tumor Lysis Syndrome in Patients with Chemo-Sensitive Hematological Malignancies by Ammar ELJack, Mohamad El Abdallah, Kadhim Al-Banaa, Kashif Chaudhry, Faisal Musa

“…After receiving one cycle therapy, he developed severe kidney injury from TLS. We initiated renal replacement therapy soon after his admission to the ICU, with marked response to therapy. …”
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Mechanical Ventilation during Extracorporeal Membrane Oxygenation in Patients with Acute Severe Respiratory Failure by Zhongheng Zhang, Wan-Jie Gu, Kun Chen, Hongying Ni

“…However, mechanical ventilation per se can cause lung injury, accelerating the disease progression. Extracorporeal membrane oxygenation (ECMO) provides an alternative to rescue patients with severe respiratory failure that conventional mechanical ventilation fails to maintain adequate gas exchange. …”
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Low-Energy Traumatic Obturator Hip Dislocation with Ipsilateral Femoral Shaft Fracture in a Patient with Omolateral Knee Arthroplasty by G. Gazzotti, L. Patrizio, S. Dall’Aglio, E. Sabetta

“…We report such a case in an older woman after a low-energy injury. She had a knee prostheses in the same limb. …”
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Disruption of the Serotonergic System after Neonatal Hypoxia-Ischemia in a Rodent Model by Kathryn M. Buller, Julie A. Wixey, Hanna E. Reinebrant

“…By understanding the fundamental mechanisms underpinning hypoxia-ischemia-induced serotonergic damage we will hopefully move closer to developing a successful clinical intervention to treat neonatal brain injury.…”
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Design of a Reconfigurable Robotic System for Flexoextension Fitted to Hand Fingers Size by J. Felipe Aguilar-Pereyra, Eduardo Castillo-Castaneda

“…Maximum trajectory tracking error is less than 3% in full range of movement and it can be compensated by the additional rotation of finger joints without injury to the user.…”
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PPARα Agonist WY-14643 Relieves Neuropathic Pain through SIRT1-Mediated Deacetylation of NF-κB by Wanshun Wen, Jinlin Wang, Biyu Zhang, Jun Wang

“…To explore the role of PPARα in NP, the effects of PPARα agonist WY-14643 on chronic constriction injury (CCI) rats were evaluated. The results showed that WY-14643 stimulation could decrease inflammation and relieve neuropathic pain, which was relative with the activation of PPARα. …”
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Acute Renal Replacement Therapy in Pediatrics by Rajit K. Basu, Derek S. Wheeler, Stuart Goldstein, Lesley Doughty

“…Acute kidney injury (AKI) independently increases morbidity and mortality in children admitted to the hospital. …”
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