Metasilicate-based alkaline mineral water improves the growth performance of weaned piglets by maintaining gut-liver axis homeostasis through microbiota-mediated secondary bile aci... by Jian Chen, Kanwar K. Malhi, Xiaowei Li, Xiangwen Xu, Jianxun Kang, Bichen Zhao, Yaru Xu, Xuenan Li, Jinlong Li

“…Our results indicated that metasilicate-based AMW effectively alleviated weaning-induced colonic or liver morphological injury and inflammatory response, as well as liver cholesterol metabolism disorders. …”
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Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions by Kyle D. Gromer, Shang-Yang Chen, Gaurav Gadhvi, Liang Feng, Colin Shearn, Swati Antala, Swati Antala, Joshua B. Wechsler, Carla M. Cuda, Cara L. Mack, Ronald J. Sokol, William J. Janssen, Richard M. Green, Harris Perlman, Deborah R. Winter, Sarah A. Taylor, Sarah A. Taylor

“…Among all subsets, the number of Ly6c+ macrophages exhibited the strongest correlation with severity of histologic liver injury by Ishak score.ConclusionsOur data identify specific pathways upregulated in Ly6c vs MHCII+ macrophage subsets in murine BA. …”
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Effects of Therapeutic Hypothermia and Minimal Enteral Nutrition on Short-Term Outcomes in Neonates with Hypoxic–Ischemic Encephalopathy: A 10-Year Experience from Oman by Manoj Malviya, Sathiya Murthi, Dhanya Jayaraj, Vidya Ramdas, Fadia Nazir Malik, Valsala Nair, Nusrabegam Marikkar, Mukesh Talreja, Tariq Sial, Prakash Manikoth, Renjan Varghese, Khalsa Ali Al Ramadhani, Salima Al Aisry, Said Al Kindi, Ahmed Al Habsi, Ranjit Torgalkar, Munawwar Ahmed, Mohammed Al Yahmadi

“…We aimed to examine TH’s effects on mortality and brain injury and evaluate the safety and effectiveness of minimal enteral feeding during TH. …”
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HMGB-1 as a predictor of major bleeding requiring activation of a massive transfusion protocol in severe trauma by Michal Frelich, Marek Bebej, Jan Pavlíček, Filip Burša, Vojtěch Vodička, Zdeněk Švagera, Adéla Kondé, Ondřej Jor, Markéta Bílená, Tereza Romanová, Peter Sklienka

“…Most patients die within 6 h of injury, which is preventable in at least 10% of cases. …”
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Pengaruh Terapi Oksigen Menggunakan Non-Rebreathing Mask Terhadap Tekanan Parsial CO2 Darah pada Pasien Cedera Kepala Sedang by Hendrizal ., Syaiful Saanin, Hafni Bachtiar

“…This study aimed to determine whether the increase in oxygen concentration in the non-rebreathing mask (NRM) will decrease the partial pressure of CO2, so that it can be used to decrease PaCO2 while PaO2 still higher to protect brain from higher of ICT (intra-cranial pressure) state in patients with head injuries. Method: This research is a Clinical Trial with one shoot pretest and posttest design in patients with moderate head injury with GCS 9-13 conducted conservative treatment at the hospital Dr. …”
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Comparison of search and rescue operations involving emergency physicians in devastating earthquakes in Turkey: a 24-year experience study by Mustafa Ferudun Celikmen, Gülbin Aydoğdu Umaç, Melih Imamoglu, Mümin Murat Yazici, Elif Çiğdem Keleş, Sarper Yilmaz

“…Identification of the injured was achieved in 54.8% (n = 23) of the Maraş group and 88.1% (n = 104) of the Marmara group, with an overall identification rate of 79.4% (n = 127) (p < 0.001). The most common injuries among the injured were lower extremity injuries (53.1%, n = 85) and upper extremity injuries (49.4%, n = 79), with the most frequent scenario being the extraction of two individuals from the same location (33.8%, n=54). …”
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Alpha-2-adrenergic receptor agonists for the prevention of delirium and cognitive decline after open heart surgery (ALPHA2PREVENT): protocol for a multicentre randomised controlled... by Eva Skovlund, Rune Haaverstad, Henrik Zetterberg, Jorunn L Helbostad, Rolf Busund, Johan Raeder, Theis Tønnessen, Torgeir Bruun Wyller, Melanie R Simpson, Nils Kristian Skjærvold, Bjørn Erik Neerland, Svein Aslak Landsverk, Ieva Martinaityte, Hilde Margrethe Norum, Geir Selbaek, Elisabeth Skaar, Arjen JC Slooter, Øyvind Sverre Svendsen, Alexander Wahba

“…We aim to study whether repurposing of clonidine can represent a novel treatment option for delirium, and the possible effects of dexmedetomidine and clonidine on long-term cognitive trajectories, motor activity patterns and biomarkers of neuronal injury, and whether these effects are associated with frailty status.Methods and analysis This five-centre, double-blind randomised controlled trial will include 900 cardiac surgery patients aged 70+ years. …”
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Laparoscopic excision of deep rectovaginal endometriosis in BSGE endometriosis centres: a multicentre prospective cohort study by Paul Smith, Lucky Saraswat, Sanjay Vyas, Thomas Ind, Ertan Saridogan, Elizabeth Ball, Edward Morris, James Clark, Tony Chalhoub, David Rowlands, Moiad Alazzam, Dominic Byrne, Tamara Curnow, Alfred Cutner, T Justin Clark, Iris Menninger, Yousri Afifi, Kevin Phillips, Saikat Banerjee, Robert Richardson, Jeremy Hawe, Barry Whitlow, Emmanuel Ofuasia, Ashwini Trehan, Tyrone Carpenter, Christian Becker, Stuart Jack, Kumar Kunde, Chris Barnick, Alan Farthing, Graham Phillips, John Bidmead, Mohamed Abdel-aty, George Botros, Marlin Mubarak, Christian Kremer, Stanley Okolo, Edmond Edi-osagi, Kamel Shehata-iskander, Gaity Ahmad, Jonathan Frappell, Brice Rodriguez, Yemi Coker, Gourab Misra, Adam Moors, Chris Guyer, Caroline Overton, Suku George, Oliver Chappatte, Richard Penketh, Funlayo Odejinmi, Keith Louden, Jon Hughes

“…Serious perioperative and postoperative complications including major haemorrhage, infection and visceral injury were recorded.Results At 6 months postsurgery, there were significant reductions in premenstrual, menstrual and non-cyclical pelvic pain, deep dyspareunia, dyschezia, low back pain and bladder pain. …”
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Multiple action sites of ultrasound on Escherichia coli and Staphylococcus aureus by Xinyu Liao, Jiao Li, Yuanjie Suo, Shiguo Chen, Xingqian Ye, Donghong Liu, Tian Ding

“…From colony results, ultrasound acted as an irreversible effect on both Eshcerichia coli and Staphylococcus aureus without sublethal injury. The result in this study also showed that a proportion of bacteria subpopulation suffered from serious damage of intracellular components (e.g. …”
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Comparative Effects of Glenzocimab and Eptifibatide on Bleeding Severity in 2 Mouse Models of Intracranial Hemorrhage by Sébastien Dupont, Héloïse Lebas, Sabrina Mavouna, Eloïse Pascal, Astride Perrot, Adrien Cogo, Marie‐Charlotte Bourrienne, Carine Farkh, Mialitiana Solo Nomenjanahary, Véronique Ollivier, Fatima Zemali, Bernhard Nieswandt, Stéphane Loyau, Martine Jandrot‐Perrus, Eric Camerer, Jean‐Philippe Desilles, Mikael Mazighi, Yacine Boulaftali, Benoît Ho‐Tin‐Noé

“…Conversely, eptifibatide caused a significant increase in intracranial bleeding in both models, and a drastic increase in death after hyperglycemia‐induced hemorrhagic transformation of cerebral ischemia–reperfusion injury. Conclusions Unlike eptifibatide, glenzocimab is safe in the setting of ICH. …”
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Open Posterolateral Ligament Plication and Lateral Ulnar Collateral Ligament Repair in Posterolateral Rotatory Instability of the Elbow Using an All-Suture Construct by Michell Ruiz Suarez, M.D., Ph.D., José Eduardo Torres Rangel, M.D., Rafael Gamba Galeazzi, M.D., Andrés Felipe Cobaleda Aristizabal, M.D.

“…Posterolateral rotatory instability of the elbow is the most common form of lateral-sided instability; it is often the result of an injury to the lateral collateral ligament complex involving the lateral ulnar collateral ligament. …”
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An idiopathic left internal iliac artery aneurysm in an 11-year-old boy: a case report by Meghdad Ghasemi Gorji, Amirhossein Baratinezhad, Rojan Abdollahzadeh Mirali

“…Abstract Background Idiopathic isolated aneurysms in pediatric patients are rare and present significant diagnostic and therapeutic challenges owing to their low incidence, small anatomical size, and the associated risks of injury to surrounding structures. Timely diagnosis and the selection of the most appropriate intervention require careful consideration. …”
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Boerhaave syndrome in a paediatric patient with diabetic ketoacidosis: A case report by Alkhalifah Yasir S.

“…Imaging studies revealed the presence of pneumomediastinum, which raised concerns about oesophageal injury and a diagnosis of Boerhaave syndrome was made. …”
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Complete and Partial Lesions of the Pyramidal Tract in the Rat Affect Qualitative Measures of Skilled Movements: Impairment in Fixations as a Model for Clumsy Behavior by Ian Q. Whishaw, Dionne M. Piecharka, Felicia R. Drever

“…Little is known about prenatal and perinatal brain injury resulting in subsequent clumsy behavior in children. …”
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Intravenous amino acids for kidney protection in patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized controlled trials by Malik Waleed Zeb Khan, Aizaz Ali, Amna Hussain, Aban Masaud Mian, Abdul Moeez, Waqas Inayat, Bushra Noor, Izhar Ali Shah, Muhammad Osama, Bushra Khan, Muhammad Sajid, Touba Azeem, Mohammad Ebad Ur Rehman, Ashraf Ali, Ubaid Khan Afridi

“…Objective To evaluate the efficacy of intravenous (IV) amino acids in preventing acute kidney injury (AKI) in patients undergoing cardiac surgery. …”
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Imaging surprise: Incidentally detected duplication of gall bladders in a case of ruptured liver abscess: A rare case report by Kaustubh Gupta, MD, Priya Das, MBBS, Gaurav Raj, MD, Vikas Singh, MS

“…Information about such rare variant anatomy must be communicated to the surgeon beforehand due to the risk of common bile duct (CBD) and hepatic artery injury during surgery. Duplication of the gall bladder is a rare malformation and may be asymptomatic or symptomatic, with symptoms being difficult to differentiate from single gall bladder pathology. …”
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Presumed Glenoid SLAP Tear in an Adolescent Football Player Belied the Presence of a Coracoid Growth Plate Fracture: A Diagnostic Conundrum by John G. Skedros, J. Hunter Marshall, John T. Cronin

“…We report the case of a 13-year-old male who sustained a right shoulder injury while playing quarterback in an American football game. …”
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Control of Cross Talk between Angiogenesis and Inflammation by Mesenchymal Stem Cells for the Treatment of Ocular Surface Diseases by Fei Li, Shao-zhen Zhao

“…Although great progress has been achieved, healing of severe ocular surface injury and immunosuppression of corneal transplantation are the most difficult and challenging step in the treatment of ocular surface disorders. …”
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Using the Woolley Motivation Typology to Heal Infidelity With Emotionally Focused Therapy by Scott R. Woolley, Réka Koren

“…Areas covered: This paper offers a practical framework for addressing infidelity by integrating Woolley’s (2011) motivation-based typology of affairs into the practice of Emotionally Focused Therapy (EFT) and the Attachment Injury Repair Model (AIRM). The typology categorizes infidelity into three broad categories, and seven specific types based on motivations, offering a lens through which couple therapists can focus their approach. …”
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Efficacy of Electroconvulsive Therapy for Neuropathic Pain Comorbid with Major Depression by Masashi Ueda, Yuki Konishi, Kohei Sakurai, Atsuko Ikenouchi, Reiji Yoshimura

“…This case indicates that ECT might be an alternative treatment for major depression associated with chronic neuropathic pain after traumatic injury.…”
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