Nitric oxide synthase inhibition decreases tolerance to hyperoxia in newborn rats by M. R. Pierce, C. A. Voelker, I. R. S. Sosenko, S. Bustamante, S. M. Olister, X.-J. Zhang, D. A. Clark, M. J. S. Miller

“…We conclude that perinatal NOS inhibition results in pulmonary artery vasoconstriction and a decreased tolerance to hyperoxia induced lung injury in newborn rats.…”
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Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement by Qian Wang, Xuefei Tian, Yuyang Wang, Yan Wang, Jialin Li, Tingting Zhao, Ping Li

“…Podocyte injury is an important pathogenesis step causing proteinuric kidney diseases such as diabetic kidney disease (DKD). …”
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Cardiopulmonary Profile in Streptozotocin-Induced Type 1 Diabetic Rats during Systemic Endotoxemia by Ching-Hsia Hung, Che-Ning Chang, Yu-Wen Chen, Yu-Chung Chen, Jann-Inn Tzeng, Jhi-Joung Wang

“…Albumin content, wet/dry weight ratio of lung, and lung injury were indistinguishable between STZ and normal rats. …”
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Novel Tubular Biomarkers Predict Renal Progression in Type 2 Diabetes Mellitus: A Prospective Cohort Study by Bancha Satirapoj, Kasemsan Aramsaowapak, Theerasak Tangwonglert, Ouppatham Supasyndh

“…Background. Tubulointerstitial injury is both a key feature of diabetic nephropathy and an important predictor of renal dysfunction. …”
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Fluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis by Isabelle Linares, Kaihua Chen, Ava Saffren, Mehran Mansouri, Vinay V. Abhyankar, Benjamin L. Miller, Stefano Begolo, Hani A. Awad, James L. McGrath

“…Abstract The aberrant vascular response associated with tendon injury results in circulating immune cell infiltration and a chronic inflammatory feedback loop leading to poor healing outcomes. …”
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Sevoflurane Preconditioning plus Postconditioning Decreases Inflammatory Response with Hemodynamic Recovery in Experimental Liver Ischemia Reperfusion by Estela Regina Ramos Figueira, Joel Avancini Rocha-Filho, Cinthia Lanchotte, Ana Maria Mendonça Coelho, Mauro Nakatani, Eduardo Ryoiti Tatebe, Jonathan Augusto Venceslau Lima, Camilla Oliveira Mendes, Bruno Camargo Rocha Paim de Araujo, Emilio Elias Abdo, Luiz Carneiro D’Albuquerque, Flavio Henrique Ferreira Galvão

“…The inhalation anesthetic sevoflurane has presented numerous biological activities, including anti-inflammatory properties and protective effects against tissue ischemic injury. This study investigated the metabolic, hemodynamic, and inflammatory effects of sevoflurane pre- and postconditioning for short periods in the rescue of liver ischemia-reperfusion (IR) injury using a rat model. …”
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Apolipoprotein A-V Is a Novel Diagnostic and Prognostic Predictor in Pediatric Patients with Sepsis: A Prospective Pilot Study in PICU by Chunxia Wang, Yun Cui, Huijie Miao, Xi Xiong, Jiaying Dou, Lujing Shao, Xiaomeng Tang, Yucai Zhang

“…In subgroup analysis, serum levels of ApoA5 were significantly correlated with sepsis-associated multiple organ dysfunction syndrome (MODS) (P<0.001), shock (P=0.002), acute kidney injury (AKI) (P<0.001), acute liver injury (ALI) (P=0.002), and gastrointestinal (GI) dysfunction (P=0.012), but not respiratory failure, brain injury, and pathogenic species (all P>0.05). …”
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TDP43 augments astrocyte inflammatory activity through mtDNA-cGAS-STING axis in NMOSD by Zhuhe Liu, Yunmeng Bai, Bingtian Xu, Haixia Wen, Kechun Chen, Jingfang Lin, Yuanyuan Wang, Jiangping Xu, Haitao Wang, Fudong Shi, Jigang Wang, Honghao Wang

“…Specific silencing astrocytic TDP43 ameliorated NMOSD-induced injury in mice, and conversely, TDP43 overexpression intensified the injury. …”
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PLL-g-HPA Hydrogel Loaded Human Umbilical Cord Mesenchymal Stem Cells Promote Burn Wound Healing in Rat Model by Regulating Inflammation Response by Tian L, Wang Z, Lei T, Feng L, Li Y, Wang K, Zhang Y, Zhang C, Liu J, Xing H, Ren W

“…A full-thickness burn wound injury model in 12 SD rats was established, and the therapeutic effect of PLL-g-HPA hydrogel combined with hUC-MSCs was detected by healing time/Histology/inflammation factor expression level.Results: The findings from SEM, FTIR, and HFF analyses demonstrated the successful synthesis of PLL-g-HPA hydrogels. …”
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Assessing Prevention Protocols by a Brief Questionnaire in the Infectious Respiratory Diseases Pandemics: An Application in Pedestrian Population in COVID-19 Pandemic by Ali Jafari-Khounigh, Alireza Razzaghi, Hamid Sharifi, Shahram Habibzadeh, Seyed Taghi Heydari, Rasool Entezarmahdi, Mostafa Farahbakhsh, Alireza Ansari Moghaddam, Mahdi Rezaei, Mohammad Saadati, Ehsan Sarbazi, Morteza Haghighi, Mina Golestani, Homayoun Sadeghi-Bazargani

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Crystalloid resuscitation is associated with decreased treatment delays and improved systolic blood pressures in a blood-constrained setting by Melissa Carvalho, Alain Chichom-Mefire, Catherine Juillard, S Ariane Christie, Rasheedat Oke, Thompson Kinge, Jean-Gustave Tsiagadigui, Mbiarikai A Mbianyor, Mark T Yost, Matt Driban, Fanny Nadia Dissak Delon, Richard Njock, Daniel Nkusu

“…BL patients presented with greater injury severity (Highest Estimated Abbreviated Injury Scale (HEAIS) 4 BL vs 3 CB vs 1 NR, p&lt;0.001), and lower median hemoglobin (8.0 g/dL BL, 11.4 g/dL CB, 10.6 g/dL NR, p&lt;0.001). …”
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Goose astrovirus induces apoptosis and endoplasmic reticulum stress in gosling hepatocytes by Zhihua Lu, Haiqin Li, Xiaona Gao, Duanfeng Fu, Haoyu Huang, Cheng Huang, Meiqin Wu, Xiaoquan Guo

“…Correlation analysis further revealed a potential relationship among ERS gene expression, apoptotic gene expression, and liver injury. In summary, GoAstV infection can lead to liver injury by interfering with ER Ca2+ homeostasis, exacerbating ERS and inducing hepatocyte apoptosis.…”
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Ethyl Acetate Extract of <i>Cichorium glandulosum</i> Activates the P21/Nrf2/HO-1 Pathway to Alleviate Oxidative Stress in a Mouse Model of Alcoholic Liver Disease by Shuwen Qi, Chunzi Zhang, Junlin Yan, Xiaoyan Ma, Yewei Zhong, Wenhui Hou, Juan Zhang, Tuxia Pang, Xiaoli Ma

“…Conclusions: CGE mitigates oxidative stress and liver injury by activating the P21/Nrf2/HO-1 pathway and regulating antioxidant genes. …”
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Fall Prevention: How To Handle a Fall by Leigh Ann Martin

“… Follow the steps in this document to decrease the chance of further injury after a fall. This document is FCS2233, one in a series of the Department of Family, Youth and Community Sciences, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611. …”
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Protecting Your Pet from Pesticides by Frederick M. Fishel

“…Fishel, explains precautionary measures that can be used to protect pets from injury due to pesticides used in and around the home. …”
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Fall Prevention: How To Handle a Fall by Leigh Ann Martin

“… Follow the steps in this document to decrease the chance of further injury after a fall. This document is FCS2233, one in a series of the Department of Family, Youth and Community Sciences, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL 32611. …”
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Sensorineural Hearing Loss following Carbon Monoxide Poisoning by Joseph P. Pillion

“…A case study is presented of a 17-year-old male who sustained an anoxic brain injury and sensorineural hearing loss secondary to carbon monoxide poisoning. …”
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Validation and Psychometric Properties of the Spanish Version of King’s Parkinson’s Disease Pain Scale by Yeray González-Zamorano, Marcos Moreno-Verdú, Josué Fernández-Carnero, Jaime Herreros-Rodríguez, Juan Pablo Romero

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Inflammation in Liver Diseases by Dechun Feng, Partha Mukhopadhyay, Ju Qiu, Hua Wang

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Septicemia and Aortic Valve Endocarditis due to Erysipelothrix rhusiopathiae in a Homeless Man by Dean Campbell, Mark Cowan

“…His course was complicated by an allergic reaction to ampicillin, urinary bladder infection, respiratory failure, and acute kidney injury. He recovered completely after aortic valve replacement and a 6-week course of intravenous ceftriaxone.…”
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