Hypoxia-Induced GST1 Exerts Protective Effects on Trophoblasts via Inhibiting Reactive Oxygen Species (ROS) Accumulation by Lingjuan Chen, Gaoli Chen, Lixuan Guo, Yaping Wang, Chengjin Ai

“…Hypoxia-induced reactive oxygen species (ROS) accumulation causes chronic trophoblast injury and contributes to preeclampsia (PE). Glutathione-S-transferase P (GSTP1) is a main regulator of ROS. …”
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A clinical study of minimal blood flow clamping combined with 3D printing technology in laparoscopic nephron-sparing surgery by Lingbo Yang, Pengtao Wei, Xiaohui Li, Jiantao Sun

“…The operation time, renal artery branch clamping time, intraoperative blood loss, postoperative renal function injury, and complication rate were compared between the two groups.ResultsThe operation time, blood loss, renal function injury, and complication rate of Group A were shorter than those of Group B (p < 0.05). …”
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Novel Anthropometric Indices as Screening Tools for Obesity: A Study on Healthy Iranians by Toktam Alirezaei, Hamid Soori, Rana Irilouzadian, Hadis Najafimehr

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Blood-Brain Barrier Abnormalities Caused by HIV-1 gp120: Mechanistic and Therapeutic Implications by Jean-Pierre Louboutin, David S. Strayer

“…Using the NMDA receptor (NMDAR-1) inhibitor, memantine, we observed partial protection from gp120-induced BBB injury. Thus, (1) HIV-envelope gp120 disrupts the BBB; (2) this occurs via lesions in brain microvessels, MMP activation and degradation of vascular basement membrane and vascular tight junctions; (3) NMDAR-1 activation plays a role in this BBB injury; and (4) antioxidant gene delivery as well as NMDAR-1 antagonists may protect the BBB.…”
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Effect of Lycium barbarum Polysaccharide on Decreasing Serum Amyloid A3 Expression through Inhibiting NF-κB Activation in a Mouse Model of Diabetic Nephropathy by Fengqi Wan, Fulin Ma, Jiaxin Wu, Xinyu Qiao, Minxue Chen, Wenjian Li, Liang Ma

“…Importantly, LBP improves renal function by lowering the levels of sCr, BUN, and microalbumin in diabetic mice and relieves the injury in the renal glomeruli and tubules of the DN mice. …”
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Clinical and Pathological Characteristics of Autoimmune Hepatitis with Acute Presentation by Yi Shen, Changli Lu, Ruoting Men, Jianping Liu, Tinghong Ye, Li Yang

“…The acute group exhibited more severe injury upon histological evaluation, with lobular inflammation and bile duct injury, especially central necrosis of the lobule, more pronounced in this group (P<0.05). …”
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Dynamic Kine Magnetic Resonance Imaging in Whiplash Patients and in Age- and Sex-Matched Controls by Karl-August Lindgren, Jyrki A Kettunen, Markku Paatelma, Raija HM Mikkonen

“…The multitude of symptoms following a whiplash injury has given rise to much discussion because of the lack of objective radiological findings. …”
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The effects of combined training on tennis-specific performance in young tennis players by Gülşah Şahin, Osman Kurttekin

“…Tennis players engage in strength training to improve their tennis-specific skills and reduce the risk of injury during matches. However, this approach may not adequately develop tennis-specific skills and could potentially increase the risk of injury among young players. …”
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A Qualitative Study of Factors Perceived to Influence Physical Activity among Young Athletes after ACL Reconstruction by Christin Zwolski, Timothy Rethorn, Staci Thomas, Jacqueline Goodway, Mark Paterno, Catherine Quatman-Yates, Laura Schmitt

“…Three overarching themes were generated during thematic analysis: 1) navigation of barriers (common obstacles, injury-related limitations, unique adaptations), 2) movement motives (ingrained desire to move, external motivators, internal motivation), and 3) movement mindset (envisions for future physical activity, perceived impact of injury, belief in the power of sports)…”
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Cardiovascular manifestations in COVID-19 patients by Jyotsna Maddury, Mani Krishna, Achukatla Kumar

“…Elevated troponin without other laboratory markers elevation suggests aggressive COVID-19 disease than myocardial injury. Stress or takotsubo cardiomyopathy occurred primarily in women with COVID-19 and these women have more severe HF. …”
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Pivotal Cytoprotective Mediators and Promising Therapeutic Strategies for Endothelial Progenitor Cell-Based Cardiovascular Regeneration by Hyunyun Kim, Sujin Kim, Sang Hong Baek, Sang-Mo Kwon

“…In response to ischemic injury signals, EPCs located in a bone marrow niche migrate to injury sites and form new vessels by secreting various vasculogenic factors including VEGF, SDF-1, and FGF, as well as by directly differentiating into endothelial cells. …”
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Cytoprotective Effect of Morchella esculenta Protein Hydrolysate and Its Derivative Against H2O2-Induced Oxidative Stress by Qiang Zhang, Caie Wu, Yujun Sun, Tingting Li, Gongjian Fan

“…This study evaluated whether MPH and G-MPH protected Caco-2 cells from H2O2-induced oxidative injury and explored the potential mechanisms of protection. …”
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EPIDEMIOLOGICAL PROFILE OF PATIENTS WITH ANKLE FRACTURE TREATED IN A TERTIARY LEVEL HOSPITAL by Adriana Cano Buric da Silva, José Carlos Baldocchi Pontin, Ana Paula Cortes Damasceno, Lucas Simões Arrebola, Cairo dos Reis Souza, Marcos Vinicius Malheiros Luzo

“…The death rate was significant when related to associated injuries, in polyfractured patients. Level of Evidence II, Retrospective study.…”
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Successful Resuscitation of a Patient with Life-Threatening Metabolic Acidosis by Hemodialysis: A Case of Ethylene Glycol Intoxication by Ikuyo Narita, Michiko Shimada, Norio Nakamura, Reiichi Murakami, Takeshi Fujita, Wakako Fukuda, Hirofumi Tomita

“…Ethylene glycol intoxication causes severe metabolic acidosis and acute kidney injury. Fomepizole has become available as its antidote. …”
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Metformin Reduces Lipotoxicity-Induced Meta-Inflammation in β-Cells through the Activation of GPR40-PLC-IP3 Pathway by Ximei Shen, Beibei Fan, Xin Hu, Liufen Luo, Yuanli Yan, Liyong Yang

“…Metformin-reduced lipotoxicity-induced β-cell meta-inflammatory injury was associated with the expression of GPR40. …”
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MitoQ Modulates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction via Regulating Nrf2 Signaling by Shengfeng Zhang, Qingniao Zhou, Youcheng Li, Yunli Zhang, Yinmei Wu

“…The current study aimed at investigating the effect of MitoQ, a mitochondrial targeted antioxidant, in the treatment of intestinal injury and its potential mechanism during sepsis. …”
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Risk factors for ischemic osteonecrosis of the femoral head after internal fixation with multiple cannulated screws for Pauwels type III femoral neck fracture by Yang Shuo

“…The results of logistic regression analysis revealed that age (> 55 years), PWB time after surgery (≤ 3 months), BMI (≥ 24 kg/m2), time from injury to surgery (> 2 days), and preoperative DM were independent risk factors for postoperative ischemic ONFH (p < 0.05). …”
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Migration, Proliferation, and Differentiation of Cord Blood Mesenchymal Stromal Cells Treated with Histone Deacetylase Inhibitor Valproic Acid by Leah A. Marquez-Curtis, Yuanyuan Qiu, April Xu, Anna Janowska-Wieczorek

“…VPA at low concentrations may be used for ex vivo treatment of MSC to increase their recruitment to sites of injury without compromising their ability to proliferate or differentiate.…”
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Differential Impacts of Soybean and Fish Oils on Hepatocyte Lipid Droplet Accumulation and Endoplasmic Reticulum Stress in Primary Rabbit Hepatocytes by Xueping Zhu, Zhihui Xiao, Yumin Xu, Xingli Zhao, Ping Cheng, Ningxun Cui, Mingling Cui, Jie Li, Xiaoli Zhu

“…While these deleterious events induce hepatocyte injury, FOLE at high doses cause only minor ER and mitochondrial damage, which has no effect on hepatic function. …”
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Genetic Deletion of Soluble Epoxide Hydrolase Attenuates Inflammation and Fibrosis in Experimental Obstructive Nephropathy by Chin-Wei Chiang, Hsueh-Te Lee, Der-Cherng Tarng, Ko-Lin Kuo, Li-Ching Cheng, Tzong-Shyuan Lee

“…Additionally, UUO-induced hydronephrosis, renal tubular injury, inflammation, and fibrosis were ameliorated in sEH−/− mice with the exception of glomerulosclerosis. …”
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