Fertility differences between two wild-type <i>Drosophila melanogaster</i> lines correlate with differences in the expression of the <i>Jheh</i> gene, which codes for an enzyme deg... by O. V. Andreenkova, N. V. Adonyeva, V. M. Efimov, N.  E. Gruntenko

“…Another factor that can affect the insect reproduction is an infection with the maternally inherited symbiotic α-proteobacterium Wolbachia. The present study is devoted to the analysis of the expression of two juvenile hormone metabolism genes encoding enzymes of its synthesis and degradation, juvenile hormone acid O-methyltransferase ( jhamt) and juvenile hormone epoxide hydrase (Jheh1), respectively, in four wild-type D. melanogaster lines, two of them being infected with Wolbachia. …”
Get full text

Identification of Potential Clusters of Signs and Symptoms to Prioritize Patients’ Eligibility for AADCd Screening by 3-OMD Testing: An Italian Delphi Consensus by Carlotta Spagnoli, Roberta Battini, Filippo Manti, Duccio Maria Cordelli, Andrea Pession, Melissa Bellini, Andrea Bordugo, Gaetano Cantalupo, Antonella Riva, Pasquale Striano, Marco Spada, Francesco Porta, Carlo Fusco

Get full text

Study on Management of Blood Transfusion Therapy in Patients with Hereditary Spherocytosis by Shiyue Ma, Lingjian Tang, Chaoli Wu, Hui Tang, Xue Pu, Jinhong Niu

“…Hereditary spherocytosis (HS) is a chronic hemolytic disorder caused by inherited defects in the red blood cell membrane. This study discusses the treatment strategy for the decline in hemoglobin level in three HS probands with moderately severe or severe hemolysis and summarizes the appropriate laboratory tests that help improve clinical management of blood transfusion in HS patients. …”
Get full text

Need for judicious selection of runoff inputs in a global flood model by Jayesh Parmar, Mohit Prakash Mohanty, Subhankar Karmakar

“…These widely adopted GFMs, capable of producing flood characteristics, require runoff input typically derived from land surface models (LSMs) or global hydrological models (GHMs), which are prone to inherit cascading uncertainties. Moreover, the utilization of a single runoff input into a GFM can produce biased and misinterpreted flood hazards due to underestimation or overestimation of GFM outputs. …”
Get full text

Phenotypic diversity of bread wheat lines with introgressions from the diploid cereal Aegilops speltoides for technological properties of grain and f lour by L. V. Shchukina, I. F. Lapochkina, T. A. Pshenichnikova

“…These lines can be used for baking bread. Line 82/00i inherited from Ae. speltoides a soft-grain endosperm, which indicates the introgression of the Ha-Sp gene, homoeoallelic to the Ha gene of bread wheat, into ‘Rodina’. …”
Get full text

Pathogenetic therapeutic approaches for endocrine diseases based on antisense oligonucleotides and RNA-interference by Olga Golounina, Ildar Minniakhmetov, Ramil Salakhov, Rita Khusainova, Ekaterina Zakharova, Igor Bychkov, Natalia Mokrysheva

Get full text

NEGATION, INCLUDING, GRADUAL OBLIVION: STATE STRATEGIES ON SOVIET HERITAGE IN GEORGIA, ARMENIA AND AZERBAIJAN by A. A. Tokarev

“…The difference lies in the ratio between pro-Soviet and anti-Soviet elements.Azerbaijanseems to maintain a pro-Soviet narrative more than the others. It inherited the Soviet cult of personality and combined this practice with a completely non-Soviet (Eastern) tradition of political dynasties covered by the election system.The Armenian political tradition includes reference to Soviet Armenia as theSecondRepublic, which distinguishes the country from the neighbors who consider themselves to be the successors of the democratic republics that emerged during the Civil War inRussia. …”
Get full text

Prevalence and spectrum of haemoglobinopathies in females of reproductive age group- A first tertiary care center experience in Punjab, North India by Vikram Narang, Anshul Jain, Sumit Grover, Ankita Soni, Monika Narang, Ashima Taneja

“…Background: Thalassemia and hemoglobinopathies are a group of inherited conditions characterized by abnormalities in the synthesis or structure of hemoglobin (Hb). …”
Get full text

Przestrzenio-czas i czaso-kultura. Uwagi o komplementarności przestrzeni, kultury, czasu i krajobrazu by Jacek L. Łapiński

“…A cultural landscape is a manifestation of collective national remembrance which was inherited through generations, society, and ethnic groups. …”
Get full text

The status of women in the Ancient East: peculiarities of marriage and family relations in Mesopotamia by I. A. Lohvynenko, Ye. S. Lohvynenko

“…On the basis of the analysis of the legislation of the state institutions of the time, the purpose of marriage was determined, that is the birth and upbringing of children who were to inherit and multiply the family property and perform the necessary sacred rites, which were to help the dead in the afterlife. …”
Get full text

US Deterrence against Russia and China (based on strategic documents of J. Biden administration) by V. I. Batyuk

“…In addition to the alliances inherited from the Cold War, the Biden administration is seeking to develop new ‘bloc structures’ in the Indo-Pacific region, in particular the Quadrilateral Security Dialogue (QUAD). …”
Get full text

A Case of Status Epilepticus in a Patient Experiencing an Acute Attack of Hereditary Angioedema by Danielle Weinberg, Steven Gayda, Kyle Hultz, Hanan Atia, Brian Kohen, Eric Boccio

“…Hereditary angioedema is inherited in an autosomal dominant pattern and results in a quantitative deficiency (HAE type I) or dysfunction (HAE type II) of the C1-esterase inhibitor (C1-INH) protein. …”
Get full text

Successful management of refractory epilepsy in creatine transporter deficiency with cannabidiol and clobazam: A case report by Maria Borrell‐Pichot, Carmen Fons, Susana Boronat, Alba Sierra‐Marcos

“…Abstract Creatine transporter deficiency (CRTR‐D) is a rare X‐linked inherited disease belonging to the group of cerebral creatine deficiency disorders. …”
Get full text

Case Report of Gastrointestinal Bleeding in an Adult with Chronic Visceral Acid Sphingomyelinase Deficiency by David Cassiman, Louis Libbrecht, Wouter Meersseman, Alexander Wilmer

“…Acid sphingomyelinase deficiency (ASMD, also known as Niemann-Pick Type A and Type B disease) is a rare, inherited metabolic disorder. Liver-related issues, including cirrhosis and variceal haemorrhage, are a leading cause of early mortality in individuals with chronic forms of ASMD. …”
Get full text

A Tale of Two Conditions: Pediatric Brugada Syndrome Unveiled—Navigating the Challenges of Coexisting Arrhythmia and Fever‐Induced ECG Pattern by Hei‐To Leung, Sit‐Yee Kwok, Fong‐Ying Shih, Kin‐Shing Lun, Tak‐Cheung Yung, Sabrina Tsao

“…ABSTRACT Background Brugada syndrome (BrS) is an inherited channelopathy characterized by right precordial ST‐segment elevation. …”
Get full text

Phenotype characterization of interspecific hybrid abalone Haliotis asinina and Haliotis squamata seed by Dinar Tri Soelistyowati, Aldilla Kusumawardhani, Muhammad Zairin Junior

“…Interspesific hybridization between abalone Haliotis asinina and Haliotis squamata is required to produce hybrid seeds having a better phenotype inherited from their parents. Crossbreeding of abalone was done in the reciprocal procedure with a natural spawning technique on mass scale. …”
Get full text

Familial Hypercholesterolemia: Genetics, Symptoms, Diagnosis and Treatment - A Literature Overview by Maciej Rutkiewicz, Sabina Przygodzka, Katarzyna Gadżała, Karolina Garbino, Katarzyna Brudniak, Antoni Szuścik, Magdalena Czyczerska

“… Familial hypercholesterolemia is a genetic disorder of lipid management, especially LDL-C. It's inherited autosomal dominant in most cases. The illness is characterized by high, low-density lipoprotein cholesterol (LDL-C) levels. …”
Get full text

From bench to bedside: Developing CRISPR/Cas-based therapy for ocular diseases by Qing Zhao, Linxin Wei, Youxin Chen

“…To date, active trials include treatments for primary open angle glaucoma with MYOC mutations, refractory herpetic viral keratitis, CEP290-associated inherited retinal degenerations, neovascular age-related macular degeneration, and retinitis pigmentosa with RHO mutations. …”
Get full text

Cerebellar lipid dysregulation in SCA3: A comparative study in patients and mice by Alexandra F. Putka, Varshasnata Mohanty, Stephanie M. Cologna, Hayley S. McLoughlin

“…Spinocerebellar ataxia type 3 (SCA3) is the most common dominantly inherited ataxia and belongs to the family of nine diseases caused by a polyglutamine expansion in the disease-causing protein. …”
Get full text

Insights on the Permian tuff beds from the Saint-Affrique Basin (Massif Central, France): an integrated geochemical and geochronological study by Poujol, Marc, Mercuzot, Mathilde, Lopez, Michel, Bourquin, Sylvie, Bruguier, Olivier, Hallot, Erwan, Beccaletto, Laurent

“…The elemental geochemistry, the presence of inherited detrital zircons and the Hf signatures of the volcanic ones indicate the involvement of an old (Proterozoic and older) basement in the magma genesis; this crustal contribution becomes more prominent towards the top of the sedimentary succession.…”
Get full text