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881
The Polymorphism of the ACE Gene Affects Left Ventricular Hypertrophy and Causes Disturbances in Left Ventricular Systolic/Diastolic Function in Patients with Autosomal Dominant Po...
Published 2014-01-01“…Autosomal dominant polycystic kidney disease (ADPKD) is one of the most frequently occurring autosomal diseases inherited in the dominant manner. Due to this, lesions in the cardiovascular system of ADPKD patients have caught the attention of clinical investigators worldwide. …”
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882
Hiroshima and Nagasaki at 65 – A Reflection
Published 2010-12-01“…And having fewer, or even none, of those surviving people will in no way diminish the significance of our actions, our shared memories, and our knowledge, to be inherited by future generations, so that never again will nuclear weapons be used, in combat or in experiments.…”
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883
An Emerging Role for IQGAP1 in Regulating Protein Traffic
Published 2010-01-01“…Membrane traffic mediates infections by intracellular pathogens and a range of degenerative human diseases arise from dysfunctions in intracellular traffic; thus, elucidating the mechanisms of cellular traffic will be important in order to understand the basis of a wide range of inherited and acquired human diseases. Recent evidence suggests that IQGAP1 plays its role in cell growth through regulating the conserved mTOR pathway. …”
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884
Primary Hyperoxaluria Type 1: Clinical, Paraclinical, and Evolutionary Aspects in Adults from One Nephrology Center
Published 2023-01-01“…Primary hyperoxaluria type 1 (PH1) is a rare and inherited condition of urolithiasis. The aim of our study was to analyze clinical, paraclinical, and evolutionary aspects of PH1 in adult patients in our Nephrology department. …”
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885
Cell-marking techniques for cell lineage tracing
Published 2017-02-01“…To trace the cell’s fate, novel methods were invented that introduce special tags into cells, the tags that would be inherited during cell divisions. Every descendent of a marked cell bears the same tag and can easily be distinguished from unrelated cellular neighbors. …”
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886
Timing of dietary effects on the epigenome and their potential protective effects against toxins
Published 2025-12-01“…Numerous studies in humans and animals suggest that diet has the potential to modify the epigenome and these modifications can be inherited transgenerationally, but few studies investigate how diet can protect against negative effects of toxins. …”
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887
Foreigner in contemporary Japanese state discourse: Constructing differences between the nation and the Other
Published 2024-10-01“…Previous research suggests that, in reality, Cool Japan is not so much in conflict with nihonjiron narratives, but rather inherits their rhetoric. However, little attention has been paid to how foreigners are represented within this program. …”
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888
Foreword
Published 2024-03-01“…Interventions to create equality of opportunities and mitigate inherited disadvantages have been considerable. Despite government and civil society efforts, the situation of children today remains dire. …”
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889
COMPARISON OF METHODS FOR OBTAINING GENETIC DIVERSITY FOR BREEDING WINTER-HARDY WHEAT IN SIBERIA
Published 2014-12-01“…Gibberellin stress in two consecutive generations induced a long deep rest in some survivors, comparable to the duration of wintering, which ensured high survival of their offspring. These changes were inherited. The harder was the selection for the duration of deep rest in «gibberellic» lines, the higher proportion of them was constituted by highly frost-resistant forms that survived under conditions of poor snow cover in the steppe. …”
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890
Germline-restricted chromosomes of the songbirds
Published 2023-11-01“…In males, it is almost always eliminated from spermatocytes. Thus, GRC is inherited almost exclusively through the maternal lineage. …”
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891
Optimization of Vehicle Paths considering Carbon Emissions in a Time-Varying Road Network
Published 2022-01-01“…The experimental results show that compared with the two classical algorithms, the simulated annealing-genetic hybrid algorithm (GA-SA) has better solution performance, inherits the robustness and potential parallelism of the genetic algorithm, and has a higher practical value. …”
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892
Lecture Transformation in Modern Higher Education
Published 2022-07-01“…The leading trend in the development of lectures in a modern university is a combination of scientific character, information value and high professionalism inherited from traditional lectures with dialogue and a variety of lecture types, an increase in interactivity to enhance the educational and communication activities of students. …”
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893
Non-coding parts of genomes as the basis of epigenetic heredity
Published 2017-11-01“…We proposed that transposons in the genome affect their inherited activation in each subsequent cell division, which causes a change in cell differentiation.…”
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894
Whole exome analysis of primary immunodeficiency
Published 2018-08-01“…The human primary immunodeficiency diseases (PIDs) refer to a rare heterogeneous group of single-gene inherited disorders causing malfunctions in the immune system, and thus the affected patients have a predisposition to severe life-threatening infections. …”
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895
The role of transposable elements in the ecological morphogenesis under the influence of stress
Published 2019-07-01“…These genes contain nucleotide sequences that interact with non-coding RNAs processed from transposons transcripts, and therefore they are under the control of epigenetic regulatory networks involving transposons. Therefore, inherited features of the location and composition of transposons, along with a change in the phenotype, play an important role in the characteristics of responding to a variety of environmental stressors. …”
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896
Targeted Regulation Of Cgrp Gene Expression
Published 2001-01-01“…This observation supports the importance of a finely tuned balance of calcium in the trigeminal neuron, which is intriguing in light of genetic evidence for calcium channel mutations in a rare form of inherited migraine. These studies suggest that modulation of MAP kinase control of the cell-specific CGRP gene enhancer may be a useful therapeutic strategy for neurovascular disorders.…”
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897
Spondylocostal Dysplasia in a 7-Year-Old Sri Lankan Girl Causing Restrictive Lung Disease: A Case Report and Review of the Literature
Published 2020-01-01“…It is a recessively inherited disorder, and commonly identified disease-causing mutations are in DLL3 gene. …”
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898
Investigating the Clinical Characteristics and PITX3Mutations of a Large Chinese Family with Anterior Segment Mesenchymal Dysgenesis and Congenital Posterior Polar Cataract
Published 2023-01-01“…The congenital posterior polar cataract with or without anterior interstitial dysplasia (ASMD) of this family was inherited in an autosomal dominant manner, and the frameshift mutation (c.640_656dup) in the PITX3 gene was the cause of ocular abnormalities observed in this family. …”
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899
BCL-2 inhibitors in hematological malignancies: biomarkers that predict response and management strategies
Published 2025-01-01“…We further analyze the tumor characteristics that result in the development of intrinsic or inherited resistance to BCL-2 inhibitors. Finally, we focus on the biomarkers that can be used to predict responses to treatment in the name of personalized medicine, with the goal of exploring alternative strategies to overcome resistance.…”
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900
UKRAINE’S ENERGY POLICY IN THE POST-SOVIET ERA
Published 2016-08-01“…However, owing to the inherited soviet infrastructure and strategic location, it has become a key transit state, capable of controlling the main flows of hydrocarbons from Russia to Europe. …”
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