CB-MNCs@ CS/HEC/GP promote wound healing in aged murine pressure ulcer model by Zhi-cheng Yang, He Lin, Guo-jun Liu, Hui Pan, Jun-lu Zhu, Xiao-hong Zhang, Feng Gao, Zhong Wang, Zhi-hao Wang

“…Results CB-MNCs@CS/HEC/GP therapy accelerated pressure ulcer wound healing, attenuated inflammatory responses, promoted cell proliferation, angiogenesis, and collagen synthesis. …”
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The effect of NLRP3 inflammasome on cardiovascular prognosis in patients with acute coronary syndrome by De-Gang Mo, Ming-Ting Liang, Li Xu, Tai Li, Qian-Feng Han, Chen Chen, Heng-Chen Yao

“…Abstract The NOD‑like receptor protein domain associated protein 3 (NLRP3) inflammasome is critical in inflammatory responses and may be a valuable prognostic biomarker in acute coronary syndrome (ACS). …”
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Blockade of 4-1BB and 4-1BBL Interaction Reduces Obesity-Induced Skeletal Muscle Inflammation by Ngoc Hoan Le, Chu-Sook Kim, Thai Hien Tu, Hye-Sun Choi, Byung-Sam Kim, Teruo Kawada, Tsuyoshi Goto, Taesun Park, Jung Han Yoon Park, Rina Yu

“…These findings indicate that 4-1BB mediates the inflammatory responses in obese skeletal muscle by interacting with its ligand 4-1BBL on macrophages. …”
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Sugemule-7 alleviates oxidative stress, neuroinflammation, and cell death, promoting synaptic plasticity recovery in mice with postpartum depression by Qiang Fu, Rui Qiu, Jiaquan Liang, Shuai Wu, Dezhi Huang, Yuxiang Qin, Qiaosheng Li, Xiaojie Shi, Xiyue Xiong, Zhongyong Jiang, Yuewen Chen, Yong Cheng

“…Furthermore, Sugemule-7 significantly improved oxidative stress levels in the serum, prefrontal cortex, and hippocampus of PPD-induced mice while also suppressing inflammatory responses and abnormal neuronal death in these brain regions. …”
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Cobalt Protoporphyrin Downregulates Hyperglycemia-Induced Inflammation and Enhances Mitochondrial Respiration in Retinal Pigment Epithelial Cells by Peng-Hsiang Fang, Tzu-Yu Lin, Chiu-Chen Huang, Yung-Chang Lin, Cheng-Hung Lai, Bill Cheng

“…Cobalt protoporphyrin (CoPP) is a compound that can reduce inflammatory responses by inducing high levels of HO-1. In the present study, the therapeutic effects of CoPP were examined in ARPE-19 cells under hyperglycemia. …”
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Acer palmatum thumb. Ethanol Extract Alleviates Interleukin-6-Induced Barrier Dysfunction and Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Re... by Kwang-Youn Kim, Tae-Woo Oh, Hyun Ju Do, Ju-Hye Yang, In Jun Yang, Yong Hyun Jeon, Young-Hoon Go, Soon-Cheol Ahn, Jin-Yeul Ma, Kwang-Il Park

“…Collectively, these data suggest that KIOM-2015E protects colitis principally by improving intestinal barrier function and promoting anti-inflammatory responses. In turn, these effects inhibit macrophage infiltration into the colon and thus may be a candidate treatment for IBD.…”
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Integrated analysis of dermatomyositis reveals heterogeneous immune infiltration and interstitial lung disease-associated endotype by Xinzhi Xu, Tianwen Qiu, Kexin Sun, Xue Han, Junxia Huang, Xiuyuan Wang, Jianchao Ge, Ji Yang

“…Transcriptomic analysis of skin samples indicated upregulated inflammatory responses and M1 macrophage infiltration in DM. …”
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Arctiin alleviates the progression of osteoarthritis by regulating the cholesterol metabolic pathway by Jiale Mai, Jiacong Xiao, Yanhuai Ma, Dawei Gong, Jianliang Li

“…ARC inhibits IL-1β-induced inflammatory responses and ECM degradation, suggesting its potential as a therapeutic agent for OA. …”
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The identification of a SARs-CoV2 S2 protein derived peptide with super-antigen-like stimulatory properties on T-cells by Thai Hien Tu, Fatima Ezzahra Bennani, Nasser Masroori, Chen Liu, Atena Nemati, Nicholas Rozza, Amichai Meir Grunbaum, Richard Kremer, Catalin Milhalcioiu, Denis-Claude Roy, Christopher E. Rudd

“…An outstanding question is whether SARS-CoV-2 protein sequences can directly induce inflammatory responses. In this study, we identify a region in the SARS-CoV-2 S2 spike protein with sequence homology to bacterial super-antigens (termed P3). …”
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Deep-Sea-Derived Isobisvertinol Targets TLR4 to Exhibit Neuroprotective Activity via Anti-Inflammatory and Ferroptosis-Inhibitory Effects by Zi-Han Xu, Ming-Min Xie, Chun-Lan Xie, Xian-Wen Yang, Jun-Song Wang

“…These diseases involve complex pathophysiological mechanisms, including inflammatory responses, oxidative stress, and ferroptosis. …”
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Predatory bacteria can intensify lung-injury in a multidrug-resistant Acinetobacter baumannii pneumonia model in rat by Zeinab Mohsenipour, Farzaneh Kianian, Behnaz Jahanbin, Hamid Reza Abtahi, Tooba Ghazanfari, Maryam Edalatifard, Saeid Amanpour, Mikael Skurnik, Parya Arazi, Mohammad Mehdi Feizabadi, Mohammad Mehdi Feizabadi

“…However, treatment with predatory bacteria not only failed to reduce the pathogen load in the lungs to the same extent as the antibiotic treatment group, but also induced acute pulmonary and systemic inflammatory responses. Therefore, the rats showed the highest septic score (21.4 at 48 h) and did not survive more than 48 h.DiscussionThis is the first report of systemic complications of using B. bacteriovorus HD100 for infection control. …”
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Improvement of Liver Transplantation Outcome by Heme Oxygenase-1-Transduced Bone Marrow Mesenchymal Stem Cells in Rats by Bin Wu, Hong-Li Song, Yang Yang, Ming-Li Yin, Bo-Ya Zhang, Yi Cao, Chong Dong, Zhong-Yang Shen

“…Summarily, we provide evidence that HO-1/MSCs improved allogeneic LTx outcomes by attenuating inflammatory responses and acute cellular rejection, as well as enhanced immunomodulatory effects compared with BMMSCs.…”
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Targeting natural antioxidant polyphenols to protect neuroinflammation and neurodegenerative diseases: a comprehensive review by Maroua Jalouli, Md Ataur Rahman, Partha Biswas, Hasanur Rahman, Abdel Halim Harrath, In-Seon Lee, In-Seon Lee, Sojin Kang, Jinwon Choi, Moon Nyeo Park, Bonglee Kim, Bonglee Kim

“…Polyphenols have been extensively studied for their ability to regulate inflammatory responses by modulating the activity of pro-inflammatory genes and influencing signal transduction pathways, thereby reducing neuroinflammation and neuronal death. …”
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Differences in metabolic characteristics between Metabolically Healthy Obesity (MHO) and Metabolically Unhealthy Obesity (MUO) in weight reduction therapy by Shiori Kawai, Hajime Yamakage, Kazuhiko Kotani, Mitsuhiko Noda, Noriko Satoh-Asahara, Koshi Hashimoto

“…Furthermore, a positive correlation was noted between changes in serum cystatin C levels and waist circumference in the MHO group, which indicated that despite the absence of metabolic disorders, the MHO group exhibited anti-inflammatory responses during weight reduction therapy. These results underscore the significance of weight reduction even for individuals with MHO.…”
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Nanostructured, Self-Assembling Peptide K5 Blocks TNF-α and PGE2 Production by Suppression of the AP-1/p38 Pathway by Woo Seok Yang, Yung Chul Park, Ji Hye Kim, Hye Ri Kim, Tao Yu, Se Eun Byeon, Larry D. Unsworth, Jaehwi Lee, Jae Youl Cho

“…First, we examined whether the K5 self-assembling peptide itself can modulate various cellular inflammatory responses. We found that peptide K5 significantly suppressed the release of tumor-necrosis-factor- (TNF-) α and prostaglandin E2 (PGE2) from RAW264.7 cells and peritoneal macrophages stimulated by lipopolysaccharide (LPS). …”
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The role of IFN-γ/CXCL10 axis in Mycoplasma pneumonia infection by Yanxia Zou, Feng Huang, Jiying Sun, Yidan Zheng, Ge Dai, Ting Wang, Canhong Zhu, Yongdong Yan, Renzheng Wang, Zhengrong Chen

“…In addition, IFN-γ-stimulated macrophages greatly promoted the trans-migration of Th1 cells. our data show that Th1 cells-derived IFN-γ augments CXCL10 production in macrophages via the JAK-STAT1 pathway, which subsequently recruits more immune cells like Th1 cells into the infection sites, thereby constituting a positive feedback loop and aggravating the type I inflammatory responses in MPP patients.…”
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Therapeutic Potential of Herbal Medicines in Combating Particulate Matter (PM)-Induced Health Effects: Insights from Recent Studies by Aekkhaluck Intharuksa, Warunya Arunotayanun, Mingkwan Na Takuathung, Yaowatat Boongla, Siripat Chaichit, Suthiwat Khamnuan, Anchalee Prasansuklab

“…Numerous herbal medicines and phytochemicals have shown efficacy in mitigating PM-induced cellular damage through their ability to counteract oxidative stress, suppress pro-inflammatory responses, and enhance cellular defense mechanisms. …”
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Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus by Zhongying Long, Longhui Liu, Huihui Qin, Sishun Zhou, Lumin Kong, Jianrong Ma, Hao Lin, Zhangfan Huang, Yi Lin, Zhongbao Li

“…EPP may have enormous potential for regulating immune and inflammatory responses. In conclusion, dietary EPP can significantly improve the intestinal health of spotted sea bass.…”
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Chronic Inflammation as a Link between Periodontitis and Carcinogenesis by Anilei Hoare, Cristopher Soto, Victoria Rojas-Celis, Denisse Bravo

“…In addition, it has been shown that several periodontitis-associated species induce the expression of genes related to cell proliferation, cell cycle, apoptosis, transport, and immune and inflammatory responses. Intriguingly, many of these pathways are linked to carcinogenesis. …”
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Construction of a potentially functional long noncoding RNA-microRNA-mRNA network in diabetic cardiomyopathy by Qiwen Cao, Zhihui Dong, Yangbo Xi, Jiana Zhong, Jianzhong Huang, Qunfeng Yang

“…Functional enrichment analysis showed that fatty acid metabolism pathway and inflammatory responses were significantly enriched in DCM. …”
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