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1121
Research Progress on the Correlation Between Microecological Flora and Endometriosis
Published 2024-05-01“…Existing studies have shown that imbalance of intestinal and reproductive tract flora can trigger local immune-inflammatory responses and cause systemic immune-inflammatory responses through cytokines and metabolic pathways, which in turn participate in the progression of EMs. …”
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1122
Roles of Inflammasomes in Inflammatory Kidney Diseases
Published 2019-01-01“…The immune system has a central role in eliminating detrimental factors, by frequently launching inflammatory responses towards pathogen infection and inner danger signal outbreak. …”
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1123
The unexpected role of the STING protein in lipid metabolism
Published 2023-04-01“…In the past decade, the stimulator of interferon genes (STING) adaptor protein has emerged as a central platform enabling the activation of inflammatory responses in the presence of cytosolic DNAs. …”
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1124
Histone demethylases in autophagy and inflammation
Published 2025-01-01“…Epigenetic changes, such as aberrant expression of histone demethylase, are actively associated not only with oncogenesis but also with inflammatory responses. Among post-translational modifications, histone lysine methylation holds significant importance. …”
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1125
Unphysiological lung strain promotes ventilation-induced lung injury via activation of the PECAM-1/Src/STAT3 signaling pathway
Published 2025-01-01“…The mechanism was validated with HUVECs exposed to overload mechanical cyclic stretch.ConclusionsThis study suggests that UPLS contributes to VILI by activating the PECAM-1/Src/STAT3 pathway and inducing inflammatory responses as well aspyroptosis.…”
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1126
Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment
Published 2014-01-01“…Moreover, chemokines have profound impacts on other types of cells associated with inflammatory responses, such as endothelial cells and fibroblasts. …”
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1127
Differential proinflammatory responses of colon epithelial cells to SARS-CoV-2 spike protein and Pseudomonas aeruginosa lipopolysaccharide
Published 2024-10-01“…Both agents are known to induce significant inflammatory responses, leading to severe clinical manifestations.…”
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1128
Possibility of alleviating dextran sulfate sodium-induced colitis in mice by modulate intestinal barrier function and gut microbiota with laminarin acetyl esters
Published 2025-03-01“…Treatment with LA significantly improved the organ index and modulated inflammatory responses by upregulating anti-inflammatory cytokines, such as IL-10 and TGF-β1. …”
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1129
Macrophage Migration Inhibitory Factor in Protozoan Infections
Published 2012-01-01“…Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. …”
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1130
Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens
Published 2025-02-01“…In previous work, we found that tissue damage caused by excessive inflammatory responses may be driven by endogenous reverse transcriptases. …”
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1131
Lysosomes finely control macrophage inflammatory function via regulating the release of lysosomal Fe2+ through TRPML1 channel
Published 2025-01-01“…Abstract Lysosomes are best known for their roles in inflammatory responses by engaging in autophagy to remove inflammasomes. …”
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1132
Sustainable Immunomodulatory via Macrophage P2Y12 Inhibition Mediated Bioactive Patche for Peritendinous Antiadhesion
Published 2025-01-01“…Abstract Persistent anti‐inflammatory responses are critical for the prevention of peritendinous adhesion. …”
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1133
Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice
Published 2015-01-01“…In this study we investigated the role of astragaloside IV (AS-IV), one of the major active constituents purified from the Chinese medicinal herb Astragalus membranaceus, in LPS-induced acute inflammatory responses in mice in vivo and examined possible underlying mechanisms. …”
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1134
Chemokine Expression in Human Astrocytes in Response to Shiga Toxin 2
Published 2012-01-01“…In the present study, we investigated the direct involvement of Stx in the inflammatory responses of human astrocytes (HASTs) treated with Stx. …”
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1135
A Subanesthetic Dose of Isoflurane during Postconditioning Ameliorates Zymosan-Induced Neutrophil Inflammation Lung Injury and Mortality in Mice
Published 2013-01-01“…In the present study, we investigated whether a subanesthetic dose of ISO (0.7%) protected against zymosan (ZY) induced inflammatory responses in the murine lung and isolated neutrophils. …”
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1136
Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block
Published 2025-02-01“…The hemodynamic indicators showed a slight reduction in intraoperative blood pressure and decreased numerical rating scale scores on the first postoperative day without significant differences in other indicators.ConclusionPreoperative SGB reduces early POCD in elderly patients who undergo laparoscopic GI surgery, possibly through the inhibition of oxidative stress and inflammatory responses.…”
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1137
Mesenchymal Stem Cells: An Excellent Candidate for the Treatment of Diabetes Mellitus
Published 2021-01-01“…Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged cells, exerting anti-inflammatory responses and producing immunoregulatory effects that can be significantly induced into insulin-producing cells (IPCs), providing an inexhaustible supply of functional β cells for cell replacement therapy and disease modeling for diabetes. …”
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1138
Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes
Published 2021-01-01“…The NLRP3 inflammasome was required for INH- and RIF-induced liver injuries that were produced by inflammatory responses, OS, the antioxidant defense system, and drug-metabolizing enzymes. …”
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1139
Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study
Published 2025-02-01“…Our study reveals elevated levels of terminal fucosylation at Asn207 and Asn211 of Hp in SP plasma, along with heightened inflammatory responses, compared to healthy controls (trial registration NCT05911711). …”
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1140
Radical Scavenging Activity-Based and AP-1-Targeted Anti-Inflammatory Effects of Lutein in Macrophage-Like and Skin Keratinocytic Cells
Published 2013-01-01“…Therefore, in the present study, we aimed to investigate the regulatory activity of lutein in the inflammatory responses of skin-derived keratinocytes or macrophages and to elucidate the mechanism of its inhibitory action. …”
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