Histological Consequences of Needle-Nerve Contact following Nerve Stimulation in a Pig Model by T. Steinfeldt, J. Graf, J. Schneider, W. Nimphius, E. Weihe, A. Borgeat, H. Wulf, T. Wiesmann

“…Conclusions. Inflammatory responses were directly related to needle-nerve contacts. …”
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Maternal Circulating Concentrations of Tumor Necrosis Factor-Alpha, Leptin, and Adiponectin in Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis by Jie Xu, Yan Hong Zhao, Yun Ping Chen, Xiao Lei Yuan, Jiao Wang, Hui Zhu, Chun Mei Lu

“…Our findings strengthen the clinical evidence that GDM is accompanied by exaggerated inflammatory responses.…”
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Safety and Efficacy of Insulin and Heparin in the Management of Hypertriglyceridemia-Induced Pancreatitis in a Patient without Diabetes: A Case Report by Luis Tolento Cortes, Jessica Trinh, Mimi Le, Philip Papayanis, Leah Tudtud-Hans, Lisa Hong

“…Acute pancreatitis (AP) leads to a variety of complications, such as local or systemic inflammatory responses as well as organ failure. While choledocholithiasis and alcohol abuse are two of the most common causes of AP, hypertriglyceridemia causes AP with an incidence rate between 2 and 5%. …”
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Unraveling the Molecular Mechanisms of Mosquito Salivary Proteins: New Frontiers in Disease Transmission and Control by Jiayin Guo, Xiaoe He, Jianli Tao, Hui Sun, Jing Yang

“…Mosquito saliva contains a variety of biologically active proteins that facilitate blood feeding by preventing blood clotting, promoting vasodilation, and modulating the host’s immune and inflammatory responses. These effects create an environment conducive to pathogen invasion and dissemination. …”
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OXIDATIVE STRESS AND ORAL HEALTH IN PEDIATRIC TYPE 1 DIABETES: A COMPARATIVE STUDY OF ANTIOXIDANT ENZYME ACTIVITY AND LIPID PEROXIDATION MARKERS by Amelia Surdu, Daniela Trifan, Irina-Georgeta Sufaru, Oana Cristina Cretu, Mihaela Monica Scutariu

“…T1DM in children is associated with elevated levels of oxidative stress, which exacerbates inflammatory responses and increases susceptibility to periodontal disease. …”
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PRRSV-2 nsp2 Ignites NLRP3 inflammasome through IKKβ-dependent dispersed trans-Golgi network translocation. by Lujie Zhang, Yanni Gao, Haoran Zhou, Xiao Liang, Xiaolin Jiang, Wenqin Gong, Yangyang Sun, Desheng Zhang, Xianwei Wang, Hans Nauwynck, Juan Bai, Ping Jiang

“…In addition, the IKKβ-dependent NLRP3 translocation to the dTGN is pivotal for pseudorabies virus (PRV) and encephalomyocarditis virus (EMCV)-induced inflammatory responses. Collectively, these results elucidate a novel mechanism of NLRP3 inflammasome activation during PRRSV-2 infection, providing valuable insights into PRRSV-2 pathogenesis.…”
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Pharmacologic Targets and Prototype Therapeutics in the Kallikrein-Kinin System: Bradykinin Receptor Agonists or Antagonists by J. N. Sharma, G.J. AL-Sherif

“…BK acts on two receptors, B1 and B2, which are linked physiologically through their natural stimuli and their common participation in a variety of inflammatory responses. Recently, numerous BK antagonists have been developed in order to treat several diseases that are due to excessive BK formation. …”
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Functional and Practical Insights Into the Genetic Basis of Takayasu Arteritis by Desiré Casares‐Marfil, Amr H. Sawalha

“…The analysis of transcription factor motifs within TAK‐associated loci revealed enrichment of the STAT and RUNX families, both characterized by their role in immune functions and inflammatory responses. The enrichment in biological processes in susceptibility loci confirmed the involvement of specific immune‐related pathways in TAK. …”
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OBTAINING AND TESTING OF MG-CA-SR BIODEGRADABLE MATERIALS USED IN MEDICINE by Kamel Earar, Ion Ciucă, Cornel Munteanu, Norin Forna, Anton Knieling, Alina Calin, Gabriela Leata

“…Despite their potential, the clinical implementation of Mg-Ca-Sr alloys faces several challenges, including precise control of degradation rates to match tissue healing, optimization of biocompatibility to prevent inflammatory responses, and addressing the complexities of industrial production for consistent quality and performance. …”
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Ghrelin Protects against the Detrimental Consequences of Porphyromonas gingivalis-Induced Akt Inactivation through S-Nitrosylation on Salivary Mucin Synthesis by Bronislaw L. Slomiany, Amalia Slomiany

“…Disturbances in nitric oxide synthase isozyme system and the impairment in salivary mucin synthesis are well-recognized features associated with oral mucosal inflammatory responses to periodontopathic bacterium, P. gingivalis. …”
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The Effect of Sleep Disruption on Cardiometabolic Health by SeokHyun Hong, Da-Been Lee, Dae-Wui Yoon, Seung-Lim Yoo, Jinkwan Kim

“…The latest evidence points to the role of sleep-induced changes in the composition and function of gut microbiota, which may contribute to metabolic dysfunction through modifications in the intestinal barrier and inflammatory responses. The NLRP3 inflammasome and NF-κB signaling pathways have been identified as crucial mediators linking sleep disruption to metabolic inflammation. …”
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Unraveling the Complex Relationship Triad between Lipids, Obesity, and Inflammation by Shahida A. Khan, Ashraf Ali, Sarah A. Khan, Solafa A. Zahran, Ghazi Damanhouri, Esam Azhar, Ishtiaq Qadri

“…The inflammatory cyclooxygenase pathway arising from arachidonic acid is a critical step in the progression of inflammatory responses. New oxygenated products of omega-3 metabolism, namely, resolvins and protectins, behave as endogenous mediators exhibiting powerful anti-inflammatory and immune-regulatory actions via the peroxisome proliferator-activated receptors (PPARs) and G protein coupled receptors (GPCRs). …”
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Metalloprotease Dependent Release of Placenta Derived Fractalkine by Monika Siwetz, Astrid Blaschitz, Julia Kremshofer, Jelena Bilic, Gernot Desoye, Berthold Huppertz, Martin Gauster

“…Increased expression and release of placental fractalkine may contribute to low grade systemic inflammatory responses in third trimester of normal pregnancy. …”
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Near-infrared light triggered in situ release of CO for enhanced therapy of glioblastoma by Juan Ge, Miaomiao Zuo, Qirong Wang, Zhen Li

“…The as-prepared nanocomposite possessed an elevated therapeutic efficiency with the assistance of CO through influencing mitochondrial respiration and depleting ATP, accompanying with the reduced inflammatory responses. By wrapping a homologous cell membrane, the nanocomposite can target GBM and accumulate in the tumor site, affording a powerful tool for precise and efficient treatment of GBM. …”
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Comparative multiomics analyses reveal the breed effect on the colonic host–microbe interactions in pig by Liang Huang, Shiqi Luo, Shuqi Liu, Mingliang Jin, Yizhen Wang, Xin Zong

“…Detailed analysis revealed that the differences in colon gene expression signatures between the JXB and DLY are mainly enriched in metabolic and inflammatory responses, with Lactobacillus and Lachnospiraceae enriched in DLY and JXB, respectively. …”
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The Toxoplasma rhoptry protein ROP55 is a major virulence factor that prevents lytic host cell death by Margarida T. Grilo Ruivo, Ji-hun Shin, Todd Lenz, Stephanie Y. Matsuno, Katherine Olivia Yanes, Arnault Graindorge, Maguy Hamie, Laurence Berry-Sterkers, Mathieu Gissot, Hiba El Hajj, Karine G. Le Roch, Melissa B. Lodoen, Maryse Lebrun, Diana Marcela Penarete-Vargas

“…RNA-Seq analysis revealed that ROP55 acts as a repressor of host pro-inflammatory responses. In THP-1 monocytes ΔROP55 infection increased NF-κB p65 nuclear translocation, IL-1β production, and GSDMD cleavage compared to wild type or complemented parasites. …”
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Dipropyl phthalate induces craniofacial chondrogenic defects in zebrafish embryos by Qinyuan Shen, Weitao Hu, Fasheng Liu, Si Dong, Xinya Peng, Yihang Zhong, Chao Chen, Yuhua Zuo, Chenkai Ge, Weirong Li, Wenwen Zha, Zhijun Ye, Zigang Cao, Lan Liao

“…In this process, DPRP induced elevated levels of oxidative stress in the craniofacial pharyngeal arch while promoting inflammatory responses. This ultimately led to craniofacial chondrogenic malformations in zebrafish. …”
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Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia by Jing Wang, Terry W. Wright, Francis Gigliotti

“…Immune-mediated inflammatory responses play an important role in the pathogenesis of Pcp, and may be even more significant in determining the outcome of Pcp than direct damage due to the organism itself. …”
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The effect of continuous positive airway pressure therapy on atrial fibrillation in patients with obstructive sleep apnea by Jiancheng Hu, Siyuan Zuo, Jiahui Qian, Fangfang Cheng, Dengji Wang, Yanyan Deng, Dasheng Lu, Dasheng Lu

“…The intricate pathophysiological pathways linking OSA to AF encompass chronic intermittent hypoxia, disruptions in the autonomic nervous system, inflammatory responses, and alterations in ion channel function. …”
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Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk by Hiroaki Konishi, Mikihiro Fujiya, Yutaka Kohgo

“…Virulent microorganisms, such as pathogenic bacteria and viruses, are recognized by pattern recognition receptors (PRRs), including toll-like receptors (TLRs) and nucleotide-binding oligomerization-domain proteins (NODs), and induce inflammatory responses in mammalian hosts. Conversely, commensal bacteria and probiotics, which symbiotically confer health benefits on the host organisms, can lodge in the host intestinal tract without inducing intestinal inflammation. …”
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