Dipeptidyl-Peptidase 4 Inhibitor Sitagliptin Ameliorates Hepatic Insulin Resistance by Modulating Inflammation and Autophagy in ob/ob Mice by Wenbin Zheng, Jing Zhou, Shasha Song, Wen Kong, Wenfang Xia, Lulu Chen, Tianshu Zeng

“…Changes in glycolipid metabolism, inflammatory responses, and autophagy in the liver were evaluated. …”
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Research Progress on the Correlation Between Microecological Flora and Endometriosis by LI Maoping, CHANG Heng

“…Existing studies have shown that imbalance of intestinal and reproductive tract flora can trigger local immune-inflammatory responses and cause systemic immune-inflammatory responses through cytokines and metabolic pathways, which in turn participate in the progression of EMs. …”
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Roles of Inflammasomes in Inflammatory Kidney Diseases by Jinjin Fan, Kaifeng Xie, Liqin Wang, Nuoyan Zheng, Xueqing Yu

“…The immune system has a central role in eliminating detrimental factors, by frequently launching inflammatory responses towards pathogen infection and inner danger signal outbreak. …”
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The unexpected role of the STING protein in lipid metabolism by Vila, Isabelle K., Laguette, Nadine

“…In the past decade, the stimulator of interferon genes (STING) adaptor protein has emerged as a central platform enabling the activation of inflammatory responses in the presence of cytosolic DNAs. …”
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Histone demethylases in autophagy and inflammation by Yaoyao Ma, Wenting Lv, Yi Guo, Tong Yin, Yujie Bai, Ziqi Liu, Chao Chen, WenjuanYang, Jiayi Feng, Wenbin Qian, Ruiling Tang, Yanting Su, Shigang Shan, Huifen Dong, Yongfen Bao, Lihua Qu

“…Epigenetic changes, such as aberrant expression of histone demethylase, are actively associated not only with oncogenesis but also with inflammatory responses. Among post-translational modifications, histone lysine methylation holds significant importance. …”
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Chemokines in Cancer Development and Progression and Their Potential as Targeting Molecules for Cancer Treatment by Naofumi Mukaida, So-ichiro Sasaki, Tomohisa Baba

“…Moreover, chemokines have profound impacts on other types of cells associated with inflammatory responses, such as endothelial cells and fibroblasts. …”
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Possibility of alleviating dextran sulfate sodium-induced colitis in mice by modulate intestinal barrier function and gut microbiota with laminarin acetyl esters by Kit-Leong Cheong, Amanullah Sabir, Suresh Veeraperumal, Franck Quero, Rui Li, Qiaoli Zhao, Karsoon Tan, Saiyi Zhong, Udayakumar Veerabagu

“…Treatment with LA significantly improved the organ index and modulated inflammatory responses by upregulating anti-inflammatory cytokines, such as IL-10 and TGF-β1. …”
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Macrophage Migration Inhibitory Factor in Protozoan Infections by Marcelo T. Bozza, Yuri C. Martins, Letícia A. M. Carneiro, Claudia N. Paiva

“…Macrophage migration inhibitory factor (MIF) is a cytokine that plays a central role in immune and inflammatory responses. In the present paper, we discussed the participation of MIF in the immune response to protozoan parasite infections. …”
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Reverse transcriptase inhibitors diminish systemic proinflammatory responses to bacterial pathogens by Karthik Hullahalli, Katherine G. Dailey, Ryan Acbay, Masataka Suzuki, George I. Balazs, Matthew K. Waldor

“…In previous work, we found that tissue damage caused by excessive inflammatory responses may be driven by endogenous reverse transcriptases. …”
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Lysosomes finely control macrophage inflammatory function via regulating the release of lysosomal Fe2+ through TRPML1 channel by Yanhong Xing, Meng-meng Wang, Feifei Zhang, Tianli Xin, Xinyan Wang, Rong Chen, Zhongheng Sui, Yawei Dong, Dongxue Xu, Xingyu Qian, Qixia Lu, Qingqing Li, Weijie Cai, Meiqin Hu, Yuqing Wang, Jun-li Cao, Derong Cui, Jiansong Qi, Wuyang Wang

“…Abstract Lysosomes are best known for their roles in inflammatory responses by engaging in autophagy to remove inflammasomes. …”
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Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice by Wei-Jian Zhang, Balz Frei

“…In this study we investigated the role of astragaloside IV (AS-IV), one of the major active constituents purified from the Chinese medicinal herb Astragalus membranaceus, in LPS-induced acute inflammatory responses in mice in vivo and examined possible underlying mechanisms. …”
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Chemokine Expression in Human Astrocytes in Response to Shiga Toxin 2 by Naomi Kioka, Koichi Minami, Akira Tamura, Norishige Yoshikawa

“…In the present study, we investigated the direct involvement of Stx in the inflammatory responses of human astrocytes (HASTs) treated with Stx. …”
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Sustainable Immunomodulatory via Macrophage P2Y12 Inhibition Mediated Bioactive Patche for Peritendinous Antiadhesion by Zaijin Tao, Shuo Wang, Jingwen Liu, Tonghe Zhu, Jia Jiang, Shen Liu, Xin Ma

“…Abstract Persistent anti‐inflammatory responses are critical for the prevention of peritendinous adhesion. …”
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Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block by Ruyue Xue, Yuexian Li, Mei Zhan, Lin Yang, Defeng Sun

“…The hemodynamic indicators showed a slight reduction in intraoperative blood pressure and decreased numerical rating scale scores on the first postoperative day without significant differences in other indicators.ConclusionPreoperative SGB reduces early POCD in elderly patients who undergo laparoscopic GI surgery, possibly through the inhibition of oxidative stress and inflammatory responses.…”
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A Subanesthetic Dose of Isoflurane during Postconditioning Ameliorates Zymosan-Induced Neutrophil Inflammation Lung Injury and Mortality in Mice by Hui Wang, Jing Fan, Nan-lin Li, Jun-tang Li, Shi-fang Yuan, Jun Yi, Ling Wang, Jiang-hao Chen, Yong-gang Lv, Qing Yao, Ting Wang, Yu-cai Wang, Rui Ling

“…In the present study, we investigated whether a subanesthetic dose of ISO (0.7%) protected against zymosan (ZY) induced inflammatory responses in the murine lung and isolated neutrophils. …”
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Mesenchymal Stem Cells: An Excellent Candidate for the Treatment of Diabetes Mellitus by Qiulan Huang, Yanting Huang, Jianping Liu

“…Mesenchymal stem cells (MSCs) are adult stem cells (ASCs) known for repairing damaged cells, exerting anti-inflammatory responses and producing immunoregulatory effects that can be significantly induced into insulin-producing cells (IPCs), providing an inexhaustible supply of functional β cells for cell replacement therapy and disease modeling for diabetes. …”
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Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes by Qiang Su, Wei Kuang, Weiyi Hao, Jing Liang, Liang Wu, Chunmei Tang, Yali Wang, Tao Liu

“…The NLRP3 inflammasome was required for INH- and RIF-induced liver injuries that were produced by inflammatory responses, OS, the antioxidant defense system, and drug-metabolizing enzymes. …”
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Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study by Taylor Roh, Sungeun Ju, So Young Park, Yeonghwan Ahn, Jiyun Chung, Miyako Nakano, Gyoungah Ryu, Young Jae Kim, Geumseo Kim, Hyewon Choi, Sung-Gwon Lee, In Soo Kim, Song-I Lee, Chaeuk Chung, Takashi Shimizu, Eiji Miyoshi, Sung-Soo Jung, Chungoo Park, Sho Yamasaki, Seung-Yeol Park, Eun-Kyeong Jo

“…Our study reveals elevated levels of terminal fucosylation at Asn207 and Asn211 of Hp in SP plasma, along with heightened inflammatory responses, compared to healthy controls (trial registration NCT05911711). …”
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Ambient fine particulate matter provokes multiple modalities of cell death via perturbation of subcellular structures by Yán Wāng

“…Notably, PM2.5 activates the NLRP3 inflammasome, amplifying inflammatory responses and contributing to chronic diseases. …”
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Activation and Regulation of Cellular Eicosanoid Biosynthesis by Thomas G. Brock, Marc Peters-Golden

“…One particular group of lipid messengers, the eicosanoids, plays a central role in regulating immune and inflammatory responses in a receptor-mediated fashion. These mediators are related in that they are all derived from one polyunsaturated fatty acid, arachidonic acid. …”
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