Anti-Inflammatory Property of the Ethanol Extract of the Root and Rhizome of Pogostemon cablin (Blanco) Benth by Chu-Wen Li, Xiao-Li Wu, Xiao-Ning Zhao, Zu-Qing Su, Hai-Ming Chen, Xiu-Fen Wang, Xiao-Jun Zhang, Hui-Fang Zeng, Jian-Nan Chen, Yu-Cui Li, Zi-Ren Su

“…Histopathologically, ERP (480 mg/kg) abated inflammatory response of the edema paw. Preliminary mechanism studies demonstrated that ERP decreased the level of MPO and MDA, increased the activities of anti-oxidant enzymes (SOD, GPx, and GRd), attenuated the productions of TNF-α, IL-1β, IL-6, PGE2 and NO, and suppressed the activities of COX-2 and iNOS. …”
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Dexmedetomidine alleviates acute kidney injury in a rat model of veno‐arterial extracorporeal membrane oxygenation by Min Yu, Shilin Wei, Xueyang Shen, Junjie Ying, Dezhi Mu, Xiangyang Wu, Yongnan Li

“…Conclusion This study demonstrated that dexmedetomidine could reduce inflammatory response and alleviate AKI during ECMO support.…”
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Role of periodontal ligament fibroblasts in periodontitis: pathological mechanisms and therapeutic potential by Yijie Huang, Ying Tang, Ruiqi Zhang, Xiao Wu, Li Yan, Xiling Chen, Qianqi Wu, Yiyan Chen, Yingtao Lv, Yuan Su

“…Additionally, this paper summarizes strategies for targeting PDLFs to treat periodontitis, involving blocking multiple stages of the inflammatory response induced by PDLFs and promoting the multidirectional transdifferentiation of PDLFs. …”
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Cybertoxicology, molecular docking, and experimental verification reveal the mechanism of action of chlorpyrifos on skin damage by Weibin Du, Wenxiang Zeng, Zhenwei Wang, Huahui Hu, Hongfeng Ruan, Gang Qu

“…In conclusion, our study suggests that CPF exposure primarily induces skin damage by disrupting tissue structure and function, mediated through apoptosis and proliferation processes in skin cells, alongside aberrant angiogenesis and heightened inflammatory response. These insights are expected to advance the development of preventive and therapeutic strategies aimed at mitigating the adverse effects of CPF exposure on the skin.…”
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Tryptophan metabolism-related gene CYP1B1 serves as a shared biomarker for both Parkinson’s disease and insomnia by Xin-Yu Li, Wen-Kai Yu, Jing-Hao Wu, Wen-Jun He, Yu-Nan Cheng, Kai Gao, Yi-Han Wei, Yu-Sheng Li

“…Subsequently, we employed CIBERSORT and single-sample gene set enrichment analysis (ssGSEA) to further investigate the association between hub genes and peripheral immune activation and inflammatory response. Additionally, gene interaction, Drug-mRNA, Transcription Factor (TF)-mRNA, and competing endogenous RNA (ceRNA) networks centered on these hub genes were constructed to explore regulatory mechanisms and potential drug interactions. …”
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Clinical Efficacy of Subhypothermia in the Treatment of Neonatal Hypoxic-Ischemic Encephalopathy Combined with Myocardial Damage by XiaoPing Dang, XiaoJian Hu, Xun Jiang, WeiGuo Chen, YuanCui Meng, Qi Pan, Fen Yang

“…Subhypothermia treatment of children with HIE combined with myocardial injury can further improve the hypoxic-ischemic state; reduce myocardial damage, oxidative stress, and inflammatory response; and has a good overall efficacy.…”
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Relationship Between Novel Inflammatory Indices and the Incidence of Postoperative Pneumonia After Endovascular Embolization for Aneurysmal Subarachnoid Hemorrhage by Li S, Li H, Qiu W, Wu B, Wang J, Li Y, Gao H

“…This study evaluated the relevance and utility of the Systemic Immuno-inflammatory Index (SII) and the Systemic Inflammatory Response Index (SIRI) in predicting pneumonia after aSAH.Methods: Two hundred and forty patients undergoing aSAH intervention were included. …”
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Effect of Total Saponins of Panax Notoginseng on Lipids Deposition of Apolipoprotein E-Knockout Mice by Changgeng FU, Ruina BAI, Yue LIU, Linzi LONG, Keji CHEN

“…CD₆₈⁺macrophage number and the macrophage aggregation were significantly reduced (all <italic>P</italic>&lt;0.05).Conclusion:PNS can regulate blood lipids, inhibit the immune inflammatory response, inhibit the lipid deposition of aortainhibiting and macrophage aggregation, which might be one of the anti-atherosclerosis mechanisms.…”
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The Effect and Mechanism of TLR9/KLF4 in FFA-Induced Adipocyte Inflammation by Cuizhe Wang, Meixiu Zhang, Jinxiu Wu, Wei Li, Xiaodan Ha, Yajuan Gu, Bo Han, Jianxin Xie, Jun Zhang

“…Thus, our research intended to observe the high FFA effects on TLR9/KLF4 expression and the downstream inflammatory factors, to explore the mechanism of inflammatory response suppressed by TLR9/KLF4. Methods. qRT-PCR and Western blot were used to detect the mRNA and protein expression levels of TLR9, KLF4, and key inflammation-related factors. …”
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A Novel Minimal Invasive Mouse Model of Extracorporeal Circulation by Shuhua Luo, Menglin Tang, Lei Du, Lina Gong, Jin Xu, Youwen Chen, Yabo Wang, Ke Lin, Qi An

“…Our results suggest that this novel, minimally invasive mouse model can recapitulate many of the clinical features of ECC-induced systemic inflammatory response and organ injury.…”
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Autoinflammatory Bone Diseases by Fatih Haşlak, Nergis Akay, Ümit Gül, Aybüke Günalp, Elif Kılıç Könte, Sezgin Şahin, Özgür Kasapçopur

“…These conditions are characterized by an exaggerated inflammatory response in the bones without any apparent etiology. …”
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Effect of Carboxymethyl chitosan-sodium alginate hydrogel loaded with Astragalus membranaceus-Panax notoginseng on wound healing in rats by Jing Li, Jing Li, Linai Li, Yue Yu, Ruixin Qin, Chaoyan Yu, Chen Chen, Youming Dong, Yadong Tan, Yunen Liu, Xuanli Liu

“…In vivo experiments of wound healing on SD rats showed that APCS hydrogels significantly accelerated skin wound healing, reduced inflammatory response, enhanced the formation of blood vessels, granulation tissues, and collagen fibers, and promoted re-epithelialization at the wound site. …”
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Taenia crassiceps-Excreted/Secreted Products Induce a Defined MicroRNA Profile that Modulates Inflammatory Properties of Macrophages by Diana Martínez-Saucedo, Juan de Dios Ruíz-Rosado, César Terrazas, Blanca E. Callejas, Abhay R. Satoskar, Santiago Partida-Sánchez, Luis I. Terrazas

“…Our previous studies indicate that Taenia crassiceps-excreted/secreted antigens (TcES) downregulate inflammatory responses in rodent models of autoimmune diseases, by promoting the generation of alternatively activated-like macrophages (M2) in vivo. …”
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Tumour Cell Lines HT-29 and FaDu Produce Proinflammatory Cytokines and Activate Neutrophils In Vitro: Possible Applications for Neutrophil-Based Antitumour Treatment by Antonio Brú, Juan-Carlos Souto, Sonia Alcolea, Rosa Antón, Angel Remacha, Mercedes Camacho, Marta Soler, Isabel Brú, Amelia Porres, Luis Vila

“…These results support the idea that tumour cells might normally induce a potent acute inflammatory response, leading to their own destruction.…”
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Comparative transcriptome analysis reveals a serotype-specific immune response in Nile tilapia (Oreochromis niloticus) infected with Streptococcus agalactiae by Renan José Casarotto Appel, Renan José Casarotto Appel, Karine Nicole Siqueira, Ioannis Konstantinidis, Maria Isabel Mello Martins, Rajesh Joshi, Lucienne Garcia Pretto-Giordano, Laurival Antônio Vilas-Boas, Jorge Manuel de Oliveira Fernandes, Jorge Manuel de Oliveira Fernandes

“…The serotype Ib strain seems promptly recognized by the host, triggering a potent inflammatory response, whereas the serotype III strain elicited a less immediate response, resulting in more pronounced central nervous system (CNS) symptoms and behavioral effects. …”
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Allogenic faecal microbiota transplantation for antibiotic-associated diarrhoea in critically ill patients (FEBATRICE)-Study protocol for a multi-centre randomised controlled trial... by Ivana Cibulkova, Veronika Rehorova, Hana Soukupova, Petr Waldauf, Monika Cahova, Jan Manak, Martin Matejovic, Frantisek Duska

“…Secondary outcomes include safety measures such as systemic inflammatory response, adverse events, and also diarrhoea recurrence within 28 days. …”
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Alteration of fecal microbiome and metabolome by mung bean coat improves diet-induced non-alcoholic fatty liver disease in mice by Dianzhi Hou, Jian Tang, Meili Huan, Fang Liu, Sumei Zhou, Qun Shen

“…Results showed that MBC could effectively alleviative the obese phenotype, reduce the lipid accumulation and insulin resistance, and improve the hepatic oxidative stress and inflammatory response. Furthermore, MBC significantly prevented the HFD-induced changes in the structure and composition of gut microbiota, characterized by promoting the bloom of Akkermansia, Lachnospiraceae_NK4A136_group, and norank_f_Muribaculaceae, and along with the elevated short-chain fatty acids concentrations. …”
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Ovario- protective effect of Moringa oleifera leaf extract against cyclophosphamide-induced oxidative ovarian damage and reproductive dysfunction in female rats by Seham Samir Soliman, Ahmed A. Suliman, Khaled Fathy, Ahmed A. Sedik

“…In addition, the antioxidant status and inflammatory response against CP were evaluated. Moreover, detailed histopathological and ultra- structural observations were conducted. …”
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PPARs in Regulation of Paraoxonases: Control of Oxidative Stress and Inflammation Pathways by Jordi Camps, Anabel García-Heredia, Anna Rull, Carlos Alonso-Villaverde, Gerard Aragonès, Raúl Beltrán-Debón, Esther Rodríguez-Gallego, Jorge Joven

“…Recent evidence suggests that PON1 and the monocyte chemoattractant protein-1 (MCP-1) are involved in coordinating the inflammatory response in damaged tissues; PPAR may be central in the regulation of these biochemical pathways. …”
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Matrine Attenuates COX-2 and ICAM-1 Expressions in Human Lung Epithelial Cells and Prevents Acute Lung Injury in LPS-Induced Mice by Chian-Jiun Liou, You-Rong Lai, Ya-Ling Chen, Yi-Hsien Chang, Zih-Ying Li, Wen-Chung Huang

“…Our findings suggest that matrine improved lung injury in mice and decreased the inflammatory response in human lung epithelial cells.…”
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