Protective Effect of Thalidomide on 2,4,6-Trinitrobenzenesulfonic Acid-Induced Experimental Colitis in Rats via the Inhibition of T Helper 17 Cells by Ying Xie, Dandan Li, Xiaoshuang Luan, Shuang Jin, Bo Yan, Feng Tian

“…The underlying mechanism may be a reduction in the expression levels of IL-6, IL-17, IL-23, and RORγt in colonic tissue and then subsequent inhibition of the differentiation and function of Th17 cells, thus further alleviating the intestinal inflammatory response.…”
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Hepatoprotective Role of 4-Octyl Itaconate in Concanavalin A-Induced Autoimmune Hepatitis by Wenchang Yang, Yaxin Wang, Peng Zhang, Tao Wang, Chengguo Li, Xin Tong, Xiangyu Zeng, Yuping Yin, Kaixiong Tao, Ruidong Li

“…In conclusion, our study indicated that OI alleviated Con A-induced hepatic damage by reducing inflammatory response, oxidative stress, and apoptosis.…”
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Molecular dynamics simulation of wild and mutant proteasome subunit beta type 8 (PSMB8) protein: Implications for restoration of inflammation in experimental autoimmune encephalomy... by Shamrat Kumar Paul, Md Saddam, Nisat Tabassum, Mahbub Hasan

“…In EAE-MS disease, the level of proteasome subunit beta type-8 (PSMB8), encoded by the PSMB8 gene, is increased and regulates the inflammatory response in this disease. In humans, the Nakajo-Nishimura Syndrome is caused by a mutation in the gene PSMB8, a part of the immunoproteasome subunit. …”
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Enterococcus faecium NCIMB 10415 Modulates Epithelial Integrity, Heat Shock Protein, and Proinflammatory Cytokine Response in Intestinal Cells by Shanti Klingspor, Angelika Bondzio, Holger Martens, Jörg R. Aschenbach, Katharina Bratz, Karsten Tedin, Ralf Einspanier, Ulrike Lodemann

“…Probiotics have shown positive effects on gastrointestinal diseases; they have barrier-modulating effects and change the inflammatory response towards pathogens in studies in vitro. …”
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Synthesis, Characterization, and In Vivo Cytokinome Profile of IL-12-Loaded PLGA Nanospheres by Ryan A. Lacinski, Justin E. Markel, Jabeen Noore, Hillary G. Pratt, Brock A. Lindsey

“…Similar trends were observed with IL-1β and CXCL-1, suggesting a decreased likelihood of progression to a systemic inflammatory response syndrome-like state. As IL-12-NS delivers logarithmically lower amounts of IL-12 than previously administered during human clinical trials, our data reflect the importance of IL-12-NS which safely create a systemic immunostimulatory environment.…”
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Azathioprine Hypersensitivity Syndrome during Treatment of Severe Interstitial Lung Disease with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis by Eri Nakano, Tomohiko Asakawa, Mea Asou, Eri Nohara, Tomoyuki Seki, Makoto Araki

“…Three exacerbations of the inflammatory response occurred during the subsequent 3 months. …”
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Effects of spray dried plasma on litter growth performance and oxidative stress and inflammation of sows kept in a hot environment by Hannah M. Bailey, Natalia S. Fanelli, Joy M. Campbell, Hans H. Stein

“…Abstract Background Feeding spray dried plasma (SDP) to weanling pigs improves growth, but there is a lack of research on how SDP impacts oxidative stress and inflammatory response in lactating sows, and performance of their piglets after weaning. …”
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C4d Deposition in Fetal Vessels of the Placenta in Neonatal Lupus Syndrome by Yuichiro Sato, Tomoko Yamaguchi, Jyunsuke Muraoka, Hajime Taniguchi, Atsushi Kisanuki, Kazunari Maekawa, Atushi Yamashita, Murasaki Aman, Yuki Kodama, Hiroshi Sameshima, Yujiro Asada

“…Our findings suggest that maternal autoantibodies affect the inflammatory response of the fetus through the placenta and that C4d deposition may be useful for diagnosing NLS.…”
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The Therapeutic Effects and Possible Mechanism of Pranoprofen in Mouse Model of Corneal Alkali Burns by Minting Chen, Abdirahman Abdinasir Gureeye, Yacouba Cissé, Lang Bai

“…Pranoprofen may alleviate inflammatory response by inhibiting the expression levels of NLRP3 and IL-1β at the early stage of corneal alkali injury, lowering the expression of MMP-13 and ultimately reducing corneal epithelial damage.…”
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Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice by Vinicius F. Carvalho, Emiliano O. Barreto, Ana Carolina S. Arantes, Magda F. Serra, Tatiana Paula T. Ferreira, Yago A. P. Jannini-Sá, Cory M. Hogaboam, Marco A. Martins, Patrícia M. R. Silva

“…Our findings show that alloxan diabetes caused attenuation of lung allergic inflammatory response in A/J mice, by a mechanism possibly associated with downregulation of IgE antibody production.…”
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Forskolin Inhibits Lipopolysaccharide-Induced Modulation of MCP-1 and GPR120 in 3T3-L1 Adipocytes through an Inhibition of NFκB by Jeanne Durendale Chiadak, Tatjana Arsenijevic, Kevin Verstrepen, Françoise Gregoire, Nargis Bolaky, Valérie Delforge, Véronique Flamand, Jason Perret, Christine Delporte

“…The aim of this study was to determine the signaling pathway by which Forskolin (FK), a cyclic adenosine monophosphate- (cAMP-) promoting agent causing positive changes in body composition in overweight and obese adult men, affects MCP-1 and GPR120 expression during an inflammatory response induced by lipopolysaccharide (LPS) in adipocytes, such as in an obese state. 3T3-L1 cells differentiated into adipocytes (DC) were stimulated with LPS in the absence or presence of FK and inhibitors of TLR-4 and inhibitor of kappa B (IκBα). …”
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Host cell responses to Candida albicans biofilm-derived extracellular vesicles by Kamila Kulig, Ewelina Wronowska, Magdalena Juszczak, Magdalena Juszczak, Marcin Zawrotniak, Justyna Karkowska-Kuleta, Maria Rapala-Kozik

“…In conclusion, for both types of EVs a predominantly pro-inflammatory effect on host was observed, highlighting their significant role in the inflammatory response during C. albicans infection.…”
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Effects of bronchoscopic alveolar lavage–assisted mechanical ventilation on postoperative pulmonary infection and inflammatory factors in patients undergoing lung cancer surgery by Hui Zhu, Haiyang Lu

“…Conclusions: BAL-assisted MV can achieve better results in treating postoperative PI than MV alone, effectively improving respiratory function and reducing systemic inflammatory response.…”
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Association of Baseline Neutrophil-to-Lymphocyte Ratio with Clinicopathological Characteristics of Papillary Thyroid Carcinoma by Dimitrios K. Manatakis, Sofia Tseleni-Balafouta, Dimitrios Balalis, Vasiliki N. Soulou, Dimitrios P. Korkolis, George H. Sakorafas, Georgios Plataniotis, Emmanouil Gontikakis

“…Whether this systemic inflammatory response, as expressed by the NLR, represents the inflammatory microenvironment leading to tumourigenesis, or is a tumour-associated phenomenon, remains to be elucidated and warrants further study.…”
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NLRP3 is a BMI-independent mediator of stable COPD by Yonca Gungor, Selin Ercan, Saliha Selin Özuygur Ermiş, Yiğit Kozalı, Gizem Kursunluoglu, Ceyda Sahan, Aylin Ozgen Alpaydin, Hulya Ayar Kayali

“…Abstract Purpose The inflammatory response in animal models of chronic obstructive pulmonary disease (COPD) is activated by the NLR-family-pyrin-domain-containing-3 (NLRP3) inflammasome pathway, which is also known to play a role in obesity-related inflammation. …”
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Clinical Effect of Emergency Dermabrasion Combined with Biological Dressing A on Wound Microcirculation and Preventing Sepsis in Deep Degree-II Burns by Huawei Shao, Ru Luo, Chuangang You, Qiong Li, Shulei Mao

“…Emergency dermabrasion combined with biological dressing A can effectively improve wound microcirculation in patients with deep degree-II burns, promote wound healing, shorten wound healing time, improve wound healing quality, effectively control inflammatory response, and prevent sepsis.…”
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Hematological profile of pulmonary tuberculosis patients before and after 1 month of taking anti-TB drugs by Ririh Jatmi Wikandari, Surati, Siti Nuryani, Sistoyono

“…The combined use of hematologic markers to assess inflammatory response before and after treatment still needs further investigation.This study was conducted in several Puskesmas in Semarang to determine the hematological profile of tuberculosis patients before and after 1 month of treatment. …”
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Rapamycin Improves Palmitate-Induced ER Stress/NF κ B Pathways Associated with Stimulating Autophagy in Adipocytes by Jiajing Yin, Liping Gu, Yufan Wang, Nengguang Fan, Yuhang Ma, Yongde Peng

“…Autophagy helps to adapt to cellular stress and involves in regulating innate inflammatory response. In present study, we examined the activity of rapamycin, a mTOR kinase inhibitor, against endoplasmic reticulum stress and inflammation in adipocytes. …”
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Effects of Placenta-Derived Mesenchymal Stem Cells on the Particulate Matter-Induced Damages in Human Middle Ear Epithelial Cells by So Young Kim, Seung Ha Oh, Jun Ho Lee, Myung-Whan Suh, Moo Kyun Park

“…The increased inflammatory response in PM-treated HMEECs was reversed using PL-MSCs. …”
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Preterm nutrition and brain development by Chiara Nava, Gianluca Lista, Enrica Lupo

“…In particular through the gut-brain axis it seems that they can regulate the inflammatory response and oxidative stress, mechanisms responsible for neurological damage of preterm infants. …”
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