The Protective Effect of Naringenin on Airway Remodeling after Mycoplasma Pneumoniae Infection by Inhibiting Autophagy-Mediated Lung Inflammation and Fibrosis by Yan Lin, Dan Tan, Qianna Kan, Zhen Xiao, Zhiyan Jiang

“…These results indicate that NRG treatment suppressed the inflammatory response and pulmonary fibrosis by inhibition of autophagy after MP infection.…”
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The Effect of High Levels Carbohydrate on Intestinal Microbiota, Metabolites, and Health of Common Carp (Cyprinus carpio L.) by Jinrui Xiong, Liping Yang, Luming Wang, Shaoyang Zhi, Mengjuan Zhao, Chunchu Xu, Leya Qu, Xiaorui Guo, Xiao Yan, Chaobin Qin, Guoxing Nie

“…In summary, dietary carbohydrates might mediate intestinal flora to regulate their metabolites and affect intestinal inflammatory response.…”
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The Efficacy of Fecal Microbiota Transplantation in Experimental Autoimmune Encephalomyelitis: Transcriptome and Gut Microbiota Profiling by Sanwang Wang, Hongliang Chen, Xin Wen, Jingjing Mu, Mingyue Sun, Xiaowen Song, Bin Liu, Jinbo Chen, Xueli Fan

“…The analysis of these genes showed that FMT mainly participated in the inflammatory response. Correlation analysis between gut microbes and transcriptome revealed that the relative abundance of Adlercreutzia was correlated with the expression of inflammation-related genes negatively, including Casp6, IL1RL2 (IL-36R), IL-17RA, TNF, CCL3, CCR5, and CCL8, and correlated with the expression of neuroprotection-related genes positively, including Snap25, Edil3, Nrn1, Cpeb3, and Gpr37. …”
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Platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio associated with disease activity in patients with Takayasu’s arteritis: a case-control study by Juan Du, Lili Pan, Taotao Li, Hua Liao

“…Background Platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR) have been reported to reflect the inflammatory response and disease activity in a variety of autoimmune diseases.Objectives This study aimed to evaluate the value of PLR and NLR as markers to monitor disease activity in Takayasu’s arteritis (TAK).Methods A retrospective case–control study involving 88 patients with TAK and 78 healthy controls was performed. …”
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Caffeoylquinic Acid Derivatives Extract of Erigeron multiradiatus Alleviated Acute Myocardial Ischemia Reperfusion Injury in Rats through Inhibiting NF-KappaB and JNK Activations by Zhifeng Zhang, Yuan Liu, Xuecong Ren, Hua Zhou, Kaishun Wang, Hao Zhang, Pei Luo

“…Our results suggested that cardioprotective effect of AE could be due to suppressing myocardial inflammatory response and blocking NF-κB and JNK activation pathway. …”
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Association of immunoglobulin G N-glycosylation with carotid atherosclerotic plaque phenotypes and actual clinical cardiovascular events: a study protocol for a longitudinal prospe... by Gehendra Mahara, Hongxia Zhang, Cuihong Tian, Xuerui Tan

“…Introduction Immune-inflammatory response plays a key role in the pathogenesis of atherosclerosis. …”
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Contrasting Effects of Systemic Monocyte/Macrophage and CD4+ T Cell Depletion in a Reversible Ureteral Obstruction Mouse Model of Chronic Kidney Disease by Lee D. Chaves, Liby Mathew, Mohammed Shakaib, Anthony Chang, Richard J. Quigg, Tipu S. Puri

“…Our results demonstrate that modulation of the inflammatory response during injury and repair altered the susceptibility of C57BL/6 mice to development of CKD in our rUUO model.…”
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Immune-Boosting and Antiviral Effects of Antioxidants in COVID-19 Pneumonia: A Therapeutic Perspective by Stefano Sanduzzi Zamparelli, Alessandro Sanduzzi Zamparelli, Marialuisa Bocchino

“…The pathogenesis of COVID-19 is marked by the overproduction of reactive oxygen species (ROS) and an excessive inflammatory response, resulting in oxidative stress and significant tissue damage, particularly in the respiratory system. …”
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Prealbumin/CRP Based Prognostic Score, a New Tool for Predicting Metastasis in Patients with Inoperable Gastric Cancer by Ali Esfahani, Nima Makhdami, Elnaz Faramarzi, Mohammad Asghari Jafarabadi, Alireza Ostadrahimi, Mousa Ghayour Nahand, Zohreh Ghoreishi

“…We aimed to assess the systemic inflammatory response (SIR) and nutritional status of these patients before the commencement of chemotherapy to find the appropriate prognostic factors and define a new score for predicting metastasis. …”
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Isolation, characterization and therapeutic efficacy of lytic bacteriophage ZK22 against Salmonella Typhimurium in mice by Yihong Sun, Qing Qu, Yanhua Huang, Shuo Zhou, Hua Xiang, Wei Wang

“…The results showed that phage ZK22 at a dose of 108 PFU/mL increased the survival rates of infected mice, effectively suppressed the dissemination and colonization of the host bacteria in the mice, and alleviated the inflammatory response caused by the infection. Conclusions In summary, bacteriophage ZK22 presents favorable application prospects as a potential biological agent for the control of Salmonella infections in livestock and poultry farming.…”
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Unveiling new perspectives about the onset of neurological and cognitive deficits in cerebral malaria: exploring cellular and neurochemical mechanisms by Renato M. S. de Lima, Luana K. R. Leão, Luana C. Martins, Adelaide da C. Fonseca Passos, Evander de J. Oliveira Batista, Anderson M. Herculano, Karen R. H. M. Oliveira

“…Various hypotheses have been proposed to explain the neurological syndrome associated to cerebral malaria condition, including vascular occlusion and sequestration, cytokine storm or inflammatory response, or a combination of these mechanisms and despite extensive research and a growing range of scientific information, the precise pathophysiological mechanism remains poorly understood. …”
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Assessment of Interleukin-1β in Saliva of Smoker and Non-smoker Patients with Chronic Periodontitis. by Solav Abdul-Qadir Mustafa, Haween T. Nanakaly, Hozan Wrya Azeez

“…The pathogenesis of periodontal disease may be affected by alterations of the inflammatory response by smoke. Interleukin-1 (IL-1β), an effective pro-inflammatory cytokine have been associated with the immunopathology of periodontitis. …”
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The Sequence of Prostaglandin-Endoperoxide Synthase 2 Gene in Women with Cervicitis by Maha A. Ahlial, Nazar Sh. Mohammed, Maysara S. Khalaf

“…Prostaglandin endo peroxide synthase2 (Cyclooxygenase-2) is a key enzyme in prostaglandin synthesis, which is coded by the PTGS2 gene, and recognized as the master switch that activates the inflammatory response; its induction leads to the biosynthesis of prostaglandins. …”
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Siglec-E augments adipose tissue inflammation by modulating TRAF3 signaling and monocytic myeloid-derived suppressor cells during obesity by Ahmed Rakib, Mousumi Mandal, Md Abdullah Al Mamun, Sonia Kiran, Nelufar Yasmen, Lexiao Li, Daniel M. Collier, Jianxiong Jiang, Frank Park, Udai P. Singh

“…We analyzed the changes in immune phenotypes, inflammatory response, adipogenesis, and levels of cytokines and chemokines after HFD and ND feeding.ResultsHFD consumption significantly increased the body weight and blood glucose levels in siglec-E KO mice relative to those of WT mice. …”
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Significance of Circulating and Crevicular Matrix Metalloproteinase-9 in Rheumatoid Arthritis-Chronic Periodontitis Association by Isabela Silosi, Manole Cojocaru, Lili Foia, Mihail Virgil Boldeanu, Florin Petrescu, Petra Surlin, Viorel Biciusca

“…Considering that RA-CP association is characterized by a disregulation of the inflammatory response, MMP-9 may play a role in the pathogenesis of RA-CP association. …”
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The role of MRO as an M2 macrophage-associated gene in non-small cell lung cancer: insights into immune infiltration, prognostic significance, and therapeutic implications by Yue Gu, Miaosen Zheng, Jing Xie

“…MRO correlated with key immune pathways, including TNFα signaling via NFκB, inflammatory response, and IL6 JAK STAT3 signaling. High MRO expression correlated with poorer overall survival (OS) and disease-specific survival (DSS). …”
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Porphyromonas gingivalis affects neutrophil pro-inflammatory activities by Agnieszka Zimny, Alicja Płonczyńska, Alicja Płonczyńska, Wiktor Jakubowski, Natalia Zubrzycka, Natalia Zubrzycka, Jan Potempa, Jan Potempa, Maja Sochalska

“…Additionally, although gingipains played a role in modulating the IL-8-dependent inflammatory response of human neutrophils, they did not affect the expression levels of pro-inflammatory cytokines TNF-α and IL-6.…”
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The Causative Pathogen Determines the Inflammatory Profile in Cerebrospinal Fluid and Outcome in Patients with Bacterial Meningitis by Denis Grandgirard, Rahel Gäumann, Boubacar Coulibaly, Jean-Pierre Dangy, Ali Sie, Thomas Junghanss, Hans Schudel, Gerd Pluschke, Stephen L. Leib

“…Background. The brain’s inflammatory response to the infecting pathogen determines the outcome of bacterial meningitis (BM), for example, the associated mortality and the extent of brain injury. …”
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New options for targeting TRPV1 receptors for cancer treatment: odorous Chinese herbal medicine by Minghui Zhang, Minghui Zhang, Zongao Wang, Zongao Wang, Shaojun Liu, Shaojun Liu, Yuxuan Li, Yuxuan Li, Yanting Gong, Yanting Gong, Min Liu, Min Liu

“…In this paper, we review the expression and significance of TRPV1 receptor in various cancer cell types, the role of TRPV1 in the apoptosis-proliferation balance, cancer cell invasion and metastasis, and tumor micro-environment, with emphasis on the mechanisms by which TRPV1 receptor mediates inflammatory response, immune system, and thus regulates cancer. …”
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Crosstalk between Macrophages and Mesenchymal Stem Cells Regulated by Biomaterials and Its Role in Bone Regeneration by Fan Gong, Thomas Groth, Chenlin Tu, Mingyan Zhao, Xinqia Huang, Jiaqi Chu

“…Moreover, the influence of biomaterials on the regulation of functions of MSCs and macrophages and the macrophage-related inflammatory response triggered by biomaterials and its specific role in osteogenesis are discussed.…”
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